Motif ID: MAZ.p2

Z-value: 0.989


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297261950.811.5e-04Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_809879 3.501 NM_006651
CPLX1
complexin 1
chr7_+_5289079 2.699 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr10_+_102495327 1.911 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr16_+_29724926 1.901 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_-_242168 1.767 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chrX_-_1291526 1.757 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr19_-_242335 1.681 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr21_+_46226072 1.662 NM_001848
COL6A1
collagen, type VI, alpha 1
chr17_-_39632845 1.660 ATXN7L3
ataxin 7-like 3
chr19_+_47480445 1.500 NM_015125
CIC
capicua homolog (Drosophila)
chr19_-_4016467 1.468 ZBTB7A
zinc finger and BTB domain containing 7A
chr1_-_36562341 1.401 NM_018166
FAM176B
family with sequence similarity 176, member B
chr19_+_54786723 1.375 NM_020719
PRR12
proline rich 12
chr19_-_1966628 1.356 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr17_+_62391216 1.332 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr9_+_139619969 1.310 ARRDC1
arrestin domain containing 1
chr18_+_75256954 1.308 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr6_+_37245860 1.298 NM_002648
PIM1
pim-1 oncogene
chr16_-_29949637 1.283 NM_031478
FAM57B
family with sequence similarity 57, member B
chr14_+_23907065 1.257 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr1_-_1465602 1.256 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr2_+_26768894 1.254 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr12_-_6668680 1.238 ZNF384
zinc finger protein 384
chr20_-_62181231 1.217 NM_005873
RGS19
regulator of G-protein signaling 19
chr21_-_44583505 1.207 C21orf2
chromosome 21 open reading frame 2
chr12_-_21818881 1.204 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr16_+_29725311 1.198 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr19_+_61344501 1.190 ZNF444
zinc finger protein 444
chr7_-_51351825 1.183 COBL
cordon-bleu homolog (mouse)
chr12_+_56435042 1.165 NM_138396
MARCH9
membrane-associated ring finger (C3HC4) 9
chr19_+_11327061 1.158 NM_001170635
NM_022737
LPPR2

lipid phosphate phosphatase-related protein type 2

chr11_-_6633427 1.155 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr8_-_41624030 1.133 NM_152568
NKX6-3
NK6 homeobox 3
chr19_-_14062230 1.129 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr20_-_21442663 1.126 NM_002509
NKX2-2
NK2 homeobox 2
chrX_+_152643516 1.110 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr20_-_62181588 1.100 NM_001039467
RGS19
regulator of G-protein signaling 19
chr19_+_8180179 1.099 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr19_-_772913 1.093 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr4_+_191245840 1.081 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr3_-_47595190 1.070 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr9_-_139564656 1.060 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chr17_+_7151984 1.053 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr11_+_65443303 1.046 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_61344341 1.036 NM_018337
ZNF444
zinc finger protein 444
chr22_+_49459935 1.036 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr11_-_133786935 1.035 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr18_+_44319365 1.032 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr1_-_40903897 1.030 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr2_+_100087812 1.029


chr19_-_55524445 1.027 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_-_4408789 1.020 NM_025241
UBXN6
UBX domain protein 6
chr17_-_2250967 1.020 NM_020310
MNT
MAX binding protein
chr9_-_129557373 1.018 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr8_-_143855438 1.002 NM_177476
NM_177477
LYNX1

Ly6/neurotoxin 1

chr12_-_6668787 0.997 NM_001039918
NM_133476
ZNF384

zinc finger protein 384

chr8_+_144706699 0.992 NM_001166237
GSDMD
gasdermin D
chr19_+_1200882 0.991 MIDN
midnolin
chr16_+_1143241 0.982 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr19_+_11327173 0.981 LPPR2
lipid phosphate phosphatase-related protein type 2
chr17_-_7061641 0.978 NM_001128827
DLG4
discs, large homolog 4 (Drosophila)
chr16_-_265868 0.973 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr17_+_7151653 0.972 EIF5A
eukaryotic translation initiation factor 5A
chr18_+_75256915 0.949 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_772966 0.948 LPPR3
lipid phosphate phosphatase-related protein type 3
chr20_-_61574259 0.944 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr9_+_139619957 0.941 ARRDC1
arrestin domain containing 1
chr1_+_35104120 0.937


chr21_+_42946719 0.934 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr12_-_6668880 0.932 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr19_+_45728270 0.926 SPTBN4
spectrin, beta, non-erythrocytic 4
chrX_+_138060 0.924 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr9_+_134447795 0.923 NM_020064
BARHL1
BarH-like homeobox 1
chr7_+_44110527 0.915 AEBP1
AE binding protein 1
chr16_+_85101734 0.897 FOXF1
forkhead box F1
chr17_+_78630793 0.889 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr19_+_45728207 0.880 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr19_+_59333232 0.878 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr17_-_77422463 0.875 ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr19_+_40958206 0.869 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr8_+_37672427 0.866 NM_025069
ZNF703
zinc finger protein 703
chr1_+_945472 0.865 AGRN
agrin
chr15_-_86600658 0.865 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr7_-_158073121 0.856 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_-_51168396 0.854 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr19_-_55763091 0.852 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr7_-_102044374 0.851 RASA4
RAS p21 protein activator 4
chr22_+_35777561 0.850 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr7_+_100111689 0.841 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_945331 0.834 NM_198576
AGRN
agrin
chr19_+_40213431 0.833 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr18_+_75256702 0.833 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr1_+_18306823 0.830 NM_032880
IGSF21
immunoglobin superfamily, member 21
chr1_-_16272523 0.825 NM_182623
FAM131C
family with sequence similarity 131, member C
chr16_-_30041767 0.823 MAPK3
mitogen-activated protein kinase 3
chr17_-_44047299 0.822 NM_024016
HOXB8
homeobox B8
chr8_-_80842452 0.816 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr16_+_85101605 0.814 NM_001451
FOXF1
forkhead box F1
chr1_-_1041321 0.813 C1orf159
chromosome 1 open reading frame 159
chr19_-_1518875 0.811 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr11_+_65443452 0.810 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr20_+_61374628 0.808 ARFGAP1
ADP-ribosylation factor GTPase activating protein 1
chr19_+_540849 0.806 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr16_-_70475381 0.803 ZNF821
zinc finger protein 821
chr7_+_100111712 0.800 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_13924287 0.800 DCAF15
DDB1 and CUL4 associated factor 15
chr9_+_139619875 0.799 NM_152285
ARRDC1
arrestin domain containing 1
chr19_+_7874774 0.798 MAP2K7
mitogen-activated protein kinase kinase 7
chr20_+_62181878 0.794 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr8_-_144750987 0.794 NM_001130053
NM_001130055
NM_001130056
NM_001195203
NM_001960
NM_032378
EEF1D





eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)





chr19_-_6230797 0.786


chr1_-_158335241 0.784 IGSF8
immunoglobulin superfamily, member 8
chr22_-_44015248 0.784 NM_001009880
KIAA0930
KIAA0930
chr9_+_139619977 0.782 ARRDC1
arrestin domain containing 1
chr11_-_2863536 0.779 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr4_+_191232653 0.777 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr14_+_103621768 0.772 NM_001080464
ASPG
asparaginase homolog (S. cerevisiae)
chr1_+_154318954 0.771 LMNA
lamin A/C
chr20_-_30534848 0.766 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr19_-_60783996 0.766 NM_152600
ZNF579
zinc finger protein 579
chr11_-_62145952 0.765 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr14_-_22891865 0.763 NM_016609
SLC22A17
solute carrier family 22, member 17
chr2_-_241408296 0.760 NM_004321
KIF1A
kinesin family member 1A
chr11_-_62146144 0.760 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr10_+_135343649 0.753 NM_012147
DUX2
double homeobox 2
chr20_+_34523231 0.753 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr11_-_69343128 0.750 NM_005247
FGF3
fibroblast growth factor 3
chr20_+_32610161 0.749 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr11_-_61441536 0.746 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr17_-_39556535 0.746 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr19_-_1188840 0.746 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr19_-_6230927 0.744 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_-_153429257 0.743 NM_001018016
NM_001018017
NM_001044390
NM_001044391
NM_001044392
NM_001044393
NM_002456
MUC1






mucin 1, cell surface associated






chr14_-_37134050 0.743 FOXA1
forkhead box A1
chr5_+_122452739 0.742 NM_001136239
PRDM6
PR domain containing 6
chr17_-_77422526 0.742 ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr11_+_64608307 0.738 ZFPL1
zinc finger protein-like 1
chr19_-_1814425 0.732 KLF16
Kruppel-like factor 16
chr11_-_64247230 0.730 NM_015080
NM_138732
NRXN2

neurexin 2

chr12_+_50686990 0.729 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr16_-_2186465 0.729 NM_020764
CASKIN1
CASK interacting protein 1
chr11_+_63337607 0.728 C11orf84
chromosome 11 open reading frame 84
chr11_-_66897584 0.728 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr2_+_24152799 0.728


chr7_-_100595552 0.727 NM_003378
VGF
VGF nerve growth factor inducible
chr7_+_28415495 0.726 LOC401317
hypothetical LOC401317
chr6_+_1335067 0.724 NM_001452
FOXF2
forkhead box F2
chr15_+_88345612 0.723 NM_198526
ZNF710
zinc finger protein 710
chr19_-_52667056 0.723 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_-_49897743 0.723 POU6F1
POU class 6 homeobox 1
chr10_+_101282679 0.722 NM_145285
NKX2-3
NK2 transcription factor related, locus 3 (Drosophila)
chr1_+_945399 0.722


chr14_-_20636337 0.719 ZNF219
zinc finger protein 219
chr19_+_1226510 0.712 NM_017914
C19orf24
chromosome 19 open reading frame 24
chr16_+_3036682 0.712 NM_022468
MMP25
matrix metallopeptidase 25
chr11_+_279113 0.711 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr22_-_29052863 0.710 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr1_+_153241665 0.707 NM_015872
ZBTB7B
zinc finger and BTB domain containing 7B
chr19_+_60803412 0.707 NM_153219
ZNF524
zinc finger protein 524
chr15_+_72209795 0.705 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_13924318 0.705 NM_138353
DCAF15
DDB1 and CUL4 associated factor 15
chr4_+_3264509 0.705 RGS12
regulator of G-protein signaling 12
chr7_-_149101227 0.704 NM_207336
ZNF467
zinc finger protein 467
chr5_-_179166378 0.704 NM_014275
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr1_-_27802688 0.703 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr22_-_19122047 0.702 SCARF2
scavenger receptor class F, member 2
chr9_+_131467837 0.701 PRRX2
paired related homeobox 2
chr12_+_93066370 0.700 NM_005761
PLXNC1
plexin C1
chr20_+_34523555 0.699 NM_183006
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr8_-_144722141 0.697 C8orf73
chromosome 8 open reading frame 73
chr22_-_19122107 0.697 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr12_+_47658502 0.695 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr17_-_39556483 0.695 HDAC5
histone deacetylase 5
chr5_+_139155569 0.692 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr15_-_38953628 0.691 NM_133639
RHOV
ras homolog gene family, member V
chr19_+_748390 0.688 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr17_+_58954418 0.686 NM_030779
NM_173092
KCNH6

potassium voltage-gated channel, subfamily H (eag-related), member 6

chr12_+_55896844 0.685 NM_007224
NXPH4
neurexophilin 4
chr4_-_1232742 0.684 CTBP1
C-terminal binding protein 1
chr14_-_20636568 0.682 NM_016423
ZNF219
zinc finger protein 219
chr19_+_52451642 0.682 CCDC9
coiled-coil domain containing 9
chr12_-_47651812 0.680 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr18_+_75256931 0.680 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr5_-_1165106 0.680 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr5_+_109052984 0.680


chr12_-_53268538 0.679 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr20_-_604822 0.676 NM_033129
SCRT2
scratch homolog 2, zinc finger protein (Drosophila)
chr1_-_15723363 0.674 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr16_+_19087035 0.672 NM_016524
SYT17
synaptotagmin XVII
chr19_-_16998449 0.671 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr9_+_139619917 0.671 ARRDC1
arrestin domain containing 1
chr12_+_6800950 0.670 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr3_-_52419086 0.670 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr19_+_45996881 0.669 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr19_+_39664706 0.668 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr17_-_77602938 0.667 NM_002917
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_11477395 0.666 ZNF653
zinc finger protein 653
chr11_+_65049152 0.666 SCYL1
SCY1-like 1 (S. cerevisiae)
chr1_-_175400441 0.665 ASTN1
astrotactin 1
chr2_+_936534 0.665 NM_018968
SNTG2
syntrophin, gamma 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 1.02e-20 GO:0065007 biological regulation
1.12 6.63e-20 GO:0050794 regulation of cellular process
1.11 4.31e-19 GO:0050789 regulation of biological process
1.06 1.39e-16 GO:0009987 cellular process
1.16 6.96e-14 GO:0080090 regulation of primary metabolic process
1.15 1.99e-13 GO:0031323 regulation of cellular metabolic process
1.16 2.51e-13 GO:0060255 regulation of macromolecule metabolic process
1.21 2.65e-13 GO:0048523 negative regulation of cellular process
1.14 8.09e-13 GO:0019222 regulation of metabolic process
1.19 9.22e-13 GO:0048519 negative regulation of biological process
1.20 4.59e-11 GO:0030154 cell differentiation
1.19 7.72e-11 GO:0048869 cellular developmental process
1.17 3.07e-10 GO:0010468 regulation of gene expression
1.16 5.25e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 6.78e-10 GO:0006351 transcription, DNA-dependent
1.18 7.78e-10 GO:0051252 regulation of RNA metabolic process
1.16 8.87e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.16 1.06e-09 GO:0048731 system development
1.29 1.31e-09 GO:0022008 neurogenesis
1.22 3.57e-09 GO:0007399 nervous system development
1.29 6.23e-09 GO:0048699 generation of neurons
1.12 1.28e-08 GO:0032502 developmental process
1.26 1.88e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.14 1.88e-08 GO:0048856 anatomical structure development
1.20 1.96e-08 GO:0023051 regulation of signaling
1.13 2.27e-08 GO:0007275 multicellular organismal development
1.17 3.11e-08 GO:0006355 regulation of transcription, DNA-dependent
1.27 3.68e-08 GO:0010605 negative regulation of macromolecule metabolic process
1.09 6.15e-08 GO:0044237 cellular metabolic process
1.25 1.20e-07 GO:0009892 negative regulation of metabolic process
1.11 1.22e-07 GO:0044260 cellular macromolecule metabolic process
1.30 1.72e-07 GO:0030182 neuron differentiation
1.15 1.94e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.32 2.10e-07 GO:0010629 negative regulation of gene expression
1.26 2.76e-07 GO:0031324 negative regulation of cellular metabolic process
1.14 2.96e-07 GO:0009889 regulation of biosynthetic process
1.20 4.18e-07 GO:0009653 anatomical structure morphogenesis
1.33 5.17e-07 GO:0045892 negative regulation of transcription, DNA-dependent
1.30 5.89e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.31 6.37e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.14 6.38e-07 GO:0031326 regulation of cellular biosynthetic process
1.43 7.50e-07 GO:0060284 regulation of cell development
1.18 1.02e-06 GO:0009059 macromolecule biosynthetic process
1.24 1.02e-06 GO:0032774 RNA biosynthetic process
1.14 1.04e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.18 1.25e-06 GO:0034645 cellular macromolecule biosynthetic process
1.14 2.06e-06 GO:0048518 positive regulation of biological process
1.08 2.10e-06 GO:0044238 primary metabolic process
1.32 3.02e-06 GO:0051253 negative regulation of RNA metabolic process
1.14 4.04e-06 GO:0048522 positive regulation of cellular process
1.28 4.07e-06 GO:0009890 negative regulation of biosynthetic process
1.07 4.78e-06 GO:0008152 metabolic process
1.28 5.64e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.36 6.32e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.29 9.66e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.14 1.20e-05 GO:0044249 cellular biosynthetic process
1.09 1.28e-05 GO:0043170 macromolecule metabolic process
1.29 1.30e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 1.69e-05 GO:0009058 biosynthetic process
1.18 1.95e-05 GO:0009966 regulation of signal transduction
1.27 1.95e-05 GO:0045595 regulation of cell differentiation
1.11 3.14e-05 GO:0016043 cellular component organization
1.12 3.69e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 3.69e-05 GO:0009790 embryo development
1.41 5.83e-05 GO:0051960 regulation of nervous system development
1.42 1.18e-04 GO:0050767 regulation of neurogenesis
1.26 1.42e-04 GO:0051254 positive regulation of RNA metabolic process
1.10 1.55e-04 GO:0071840 cellular component organization or biogenesis
1.25 2.15e-04 GO:0010628 positive regulation of gene expression
1.15 2.34e-04 GO:0048513 organ development
1.21 2.45e-04 GO:0048468 cell development
1.21 2.65e-04 GO:0050793 regulation of developmental process
1.45 2.67e-04 GO:0045664 regulation of neuron differentiation
1.17 4.57e-04 GO:0051239 regulation of multicellular organismal process
1.19 5.19e-04 GO:0010646 regulation of cell communication
1.26 5.23e-04 GO:0048666 neuron development
1.23 5.31e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 8.62e-04 GO:0090304 nucleic acid metabolic process
1.25 9.68e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 1.22e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.11 1.29e-03 GO:0071842 cellular component organization at cellular level
1.25 1.43e-03 GO:0009887 organ morphogenesis
1.10 1.57e-03 GO:0051234 establishment of localization
1.21 1.90e-03 GO:0051128 regulation of cellular component organization
1.14 2.13e-03 GO:0016070 RNA metabolic process
1.17 2.66e-03 GO:0031325 positive regulation of cellular metabolic process
1.11 2.71e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.10 2.74e-03 GO:0006810 transport
1.10 3.20e-03 GO:0034641 cellular nitrogen compound metabolic process
1.13 3.29e-03 GO:0010467 gene expression
1.30 3.46e-03 GO:0009792 embryo development ending in birth or egg hatching
1.12 3.58e-03 GO:0065008 regulation of biological quality
1.19 3.99e-03 GO:0032879 regulation of localization
1.26 4.48e-03 GO:0031175 neuron projection development
1.21 5.27e-03 GO:2000026 regulation of multicellular organismal development
1.09 6.34e-03 GO:0006807 nitrogen compound metabolic process
1.16 7.32e-03 GO:0009893 positive regulation of metabolic process
1.16 8.28e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.37 1.00e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.29 1.02e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.29 1.03e-02 GO:0043009 chordate embryonic development
1.19 1.26e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.88 1.50e-02 GO:0001708 cell fate specification
1.26 1.62e-02 GO:0007268 synaptic transmission
1.19 1.86e-02 GO:0009891 positive regulation of biosynthetic process
1.09 2.03e-02 GO:0051179 localization
1.20 2.09e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.24 3.01e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.25 3.47e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.24 3.56e-02 GO:0019226 transmission of nerve impulse
1.24 3.56e-02 GO:0035637 multicellular organismal signaling
1.12 3.57e-02 GO:0048583 regulation of response to stimulus
1.14 3.72e-02 GO:0035556 intracellular signal transduction
1.19 4.69e-02 GO:0016192 vesicle-mediated transport
1.98 4.75e-02 GO:0048709 oligodendrocyte differentiation
1.27 4.78e-02 GO:0048598 embryonic morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 6.08e-37 GO:0005622 intracellular
1.09 4.64e-36 GO:0044424 intracellular part
1.09 6.01e-25 GO:0043226 organelle
1.10 1.10e-24 GO:0043227 membrane-bounded organelle
1.09 2.48e-24 GO:0043229 intracellular organelle
1.10 3.15e-24 GO:0043231 intracellular membrane-bounded organelle
1.10 2.47e-22 GO:0005737 cytoplasm
1.12 1.25e-17 GO:0005634 nucleus
1.09 5.20e-11 GO:0044444 cytoplasmic part
1.03 5.79e-11 GO:0005623 cell
1.03 7.11e-11 GO:0044464 cell part
1.15 1.39e-07 GO:0044428 nuclear part
1.08 5.17e-07 GO:0044422 organelle part
1.08 1.15e-06 GO:0044446 intracellular organelle part
1.16 1.41e-06 GO:0031981 nuclear lumen
1.13 1.70e-05 GO:0070013 intracellular organelle lumen
1.13 1.76e-05 GO:0043233 organelle lumen
1.13 2.25e-05 GO:0031974 membrane-enclosed lumen
1.13 4.79e-05 GO:0005829 cytosol
1.31 6.73e-05 GO:0043005 neuron projection
1.29 4.44e-04 GO:0045202 synapse
1.17 1.93e-03 GO:0005794 Golgi apparatus
1.41 2.04e-03 GO:0043025 neuronal cell body
1.15 2.80e-03 GO:0005654 nucleoplasm
1.13 3.10e-03 GO:0012505 endomembrane system
1.40 3.11e-03 GO:0044297 cell body
1.38 8.92e-03 GO:0030424 axon
1.10 1.16e-02 GO:0031090 organelle membrane
1.20 1.87e-02 GO:0030054 cell junction
1.18 1.94e-02 GO:0031988 membrane-bounded vesicle
1.18 2.63e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.48 2.69e-02 GO:0005925 focal adhesion
1.16 3.91e-02 GO:0031982 vesicle
1.27 4.31e-02 GO:0044456 synapse part
1.16 4.62e-02 GO:0042995 cell projection
1.53 4.86e-02 GO:0033267 axon part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.07 1.06e-25 GO:0005488 binding
1.12 1.31e-25 GO:0005515 protein binding
1.38 2.34e-21 GO:0001071 nucleic acid binding transcription factor activity
1.38 2.34e-21 GO:0003700 sequence-specific DNA binding transcription factor activity
1.44 5.22e-20 GO:0043565 sequence-specific DNA binding
1.29 9.18e-13 GO:0030528 transcription regulator activity
1.18 3.40e-12 GO:0003677 DNA binding
1.13 5.91e-09 GO:0003676 nucleic acid binding
1.41 5.97e-06 GO:0005261 cation channel activity
1.10 1.21e-05 GO:0046872 metal ion binding
1.14 1.99e-05 GO:0008270 zinc ion binding
1.10 1.99e-05 GO:0043169 cation binding
1.09 2.47e-05 GO:0043167 ion binding
1.46 4.78e-05 GO:0005244 voltage-gated ion channel activity
1.46 4.78e-05 GO:0022832 voltage-gated channel activity
1.30 8.93e-05 GO:0019904 protein domain specific binding
1.22 2.81e-04 GO:0019899 enzyme binding
1.42 4.02e-04 GO:0010843 promoter binding
1.33 4.41e-04 GO:0016563 transcription activator activity
1.33 5.91e-04 GO:0022836 gated channel activity
1.49 6.44e-04 GO:0022843 voltage-gated cation channel activity
1.28 8.15e-04 GO:0015267 channel activity
1.29 8.83e-04 GO:0005216 ion channel activity
1.28 1.05e-03 GO:0022803 passive transmembrane transporter activity
1.28 1.44e-03 GO:0022838 substrate-specific channel activity
1.39 1.91e-03 GO:0000975 regulatory region DNA binding
1.39 1.91e-03 GO:0001067 regulatory region nucleic acid binding
1.39 1.91e-03 GO:0044212 transcription regulatory region DNA binding
1.26 2.14e-03 GO:0030695 GTPase regulator activity
1.24 2.41e-03 GO:0008092 cytoskeletal protein binding
1.25 3.13e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.11 3.21e-03 GO:0046914 transition metal ion binding
1.63 5.06e-03 GO:0008017 microtubule binding
1.30 1.05e-02 GO:0008134 transcription factor binding
1.10 2.10e-02 GO:0000166 nucleotide binding
1.46 2.16e-02 GO:0015631 tubulin binding
1.18 3.00e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor