Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.484


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78520634-0.712.0e-03Click!
ARNTchr1_-_149115686-0.467.4e-02Click!
AHRchr7_+_17304707-0.332.1e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_163754903 1.680 LOC100526820
hypothetical LOC100526820
chr2_+_203208064 1.359 NM_173511
 FAM117B
family with sequence similarity 117, member B
chr12_+_53229625 1.246 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr12_+_101875581 1.197 NM_004316
 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr1_+_6767968 1.146 NM_001195563
NM_015215
 CAMTA1

calmodulin binding transcription activator 1

chr9_-_133141726 1.066 NM_033387
 FAM78A
family with sequence similarity 78, member A
chr20_+_20296744 1.050 NM_002196
 INSM1
insulinoma-associated 1
chr14_-_22840249 1.040


chr15_+_81906983 1.028 NM_003027
 SH3GL3
SH3-domain GRB2-like 3
chr8_+_85258056 1.007 NM_173848
 RALYL
RALY RNA binding protein-like
chr18_+_53253775 0.994 NM_004852
 ONECUT2
one cut homeobox 2
chr8_+_85258007 0.971 NM_001100392
NM_001100393
 RALYL

RALY RNA binding protein-like

chrX_+_37429927 0.944 NM_021083
 XK
X-linked Kx blood group (McLeod syndrome)
chr1_+_30964199 0.916 LOC100129196
hypothetical LOC100129196
chr20_-_30636535 0.867 LOC284804
hypothetical protein LOC284804
chrX_-_132947141 0.840 GPC3
glypican 3
chr17_-_24253821 0.840 NM_144683
 DHRS13
dehydrogenase/reductase (SDR family) member 13
chr14_+_32478209 0.834 NM_001164749
NM_001165893
NM_022123
NM_173159
 NPAS3



neuronal PAS domain protein 3



chr3_+_39826032 0.819 NM_015460
 MYRIP
myosin VIIA and Rab interacting protein
chr3_+_6877797 0.819 NM_000844
NM_181874
 GRM7

glutamate receptor, metabotropic 7


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 102 entries
enrichment   p-value GO term description
2.57 3.80e-04 GO:0021537 telencephalon development
2.37 4.75e-02 GO:0021953 central nervous system neuron differentiation
2.25 1.48e-05 GO:0030900 forebrain development
1.95 2.15e-07 GO:0007420 brain development
1.92 1.43e-02 GO:0016569 covalent chromatin modification
1.92 2.00e-02 GO:0016570 histone modification
1.80 8.37e-04 GO:0006412 translation
1.79 2.70e-07 GO:0007417 central nervous system development
1.77 2.71e-02 GO:0050767 regulation of neurogenesis
1.72 4.63e-04 GO:0006397 mRNA processing
1.72 8.99e-03 GO:0009141 nucleoside triphosphate metabolic process
1.71 1.45e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.70 6.44e-03 GO:0009259 ribonucleotide metabolic process
1.70 4.45e-02 GO:0010608 posttranscriptional regulation of gene expression
1.69 2.85e-03 GO:0016568 chromatin modification
1.68 3.90e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.68 4.42e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.67 2.39e-04 GO:0006325 chromatin organization
1.67 2.41e-02 GO:0009150 purine ribonucleotide metabolic process
1.66 1.73e-06 GO:0006396 RNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
5.45 1.76e-02 GO:0035098 ESC/E(Z) complex
4.43 7.03e-04 GO:0031519 PcG protein complex
3.89 2.67e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.60 1.48e-02 GO:0034708 methyltransferase complex
2.60 1.48e-02 GO:0035097 histone methyltransferase complex
1.72 1.22e-02 GO:0000785 chromatin
1.65 1.32e-05 GO:0030529 ribonucleoprotein complex
1.63 5.07e-08 GO:0044451 nucleoplasm part
1.48 5.43e-09 GO:0005654 nucleoplasm
1.40 3.78e-09 GO:0031981 nuclear lumen
1.38 2.58e-10 GO:0044428 nuclear part
1.37 5.06e-10 GO:0070013 intracellular organelle lumen
1.36 6.58e-10 GO:0031974 membrane-enclosed lumen
1.35 4.21e-09 GO:0043233 organelle lumen
1.29 1.06e-20 GO:0005634 nucleus
1.22 7.01e-06 GO:0032991 macromolecular complex
1.19 7.10e-21 GO:0043231 intracellular membrane-bounded organelle
1.19 8.03e-21 GO:0043227 membrane-bounded organelle
1.18 7.03e-08 GO:0044446 intracellular organelle part
1.18 2.73e-02 GO:0043228 non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.72 3.96e-12 GO:0003723 RNA binding
1.53 5.75e-08 GO:0030528 transcription regulator activity
1.41 8.45e-13 GO:0000166 nucleotide binding
1.41 6.98e-03 GO:0019899 enzyme binding
1.40 8.36e-03 GO:0016301 kinase activity
1.39 3.20e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.37 2.13e-16 GO:0003676 nucleic acid binding
1.36 4.24e-03 GO:0001071 nucleic acid binding transcription factor activity
1.36 4.24e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 5.64e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.33 6.41e-06 GO:0017076 purine nucleotide binding
1.33 2.04e-04 GO:0030554 adenyl nucleotide binding
1.32 1.10e-05 GO:0032553 ribonucleotide binding
1.32 1.10e-05 GO:0032555 purine ribonucleotide binding
1.32 3.13e-04 GO:0005524 ATP binding
1.32 3.89e-04 GO:0032559 adenyl ribonucleotide binding
1.30 2.16e-04 GO:0016740 transferase activity
1.27 6.80e-05 GO:0003677 DNA binding
1.16 4.72e-09 GO:0005515 protein binding
1.10 8.96e-11 GO:0005488 binding