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• Activity deltas table
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.484

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_163754903	1.680		LOC100526820	hypothetical LOC100526820
chr2_+_203208064	1.359	NM_173511	FAM117B	family with sequence similarity 117, member B
chr12_+_53229625	1.246		PDE1B	phosphodiesterase 1B, calmodulin-dependent
chr12_+_101875581	1.197	NM_004316	ASCL1	achaete-scute complex homolog 1 (Drosophila)
chr1_+_6767968	1.146	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr9_-_133141726	1.066	NM_033387	FAM78A	family with sequence similarity 78, member A
chr20_+_20296744	1.050	NM_002196	INSM1	insulinoma-associated 1
chr14_-_22840249	1.040
chr15_+_81906983	1.028	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr8_+_85258056	1.007	NM_173848	RALYL	RALY RNA binding protein-like
chr18_+_53253775	0.994	NM_004852	ONECUT2	one cut homeobox 2
chr8_+_85258007	0.971	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chrX_+_37429927	0.944	NM_021083	XK	X-linked Kx blood group (McLeod syndrome)
chr1_+_30964199	0.916		LOC100129196	hypothetical LOC100129196
chr20_-_30636535	0.867		LOC284804	hypothetical protein LOC284804
chrX_-_132947141	0.840		GPC3	glypican 3
chr17_-_24253821	0.840	NM_144683	DHRS13	dehydrogenase/reductase (SDR family) member 13
chr14_+_32478209	0.834	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr3_+_39826032	0.819	NM_015460	MYRIP	myosin VIIA and Rab interacting protein
chr3_+_6877797	0.819	NM_000844 NM_181874	GRM7	glutamate receptor, metabotropic 7
chr18_+_22060383	0.808	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_61320213	0.800	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr10_+_94439658	0.727	NM_002729	HHEX	hematopoietically expressed homeobox
chr6_-_10520592	0.722	NM_001032280	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_-_44370537	0.718		CDH22	cadherin 22, type 2
chr5_-_81082699	0.693	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr6_+_126112506	0.689		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr18_+_53170718	0.683	NM_015879	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr9_-_100510657	0.681	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr17_-_71747867	0.678	NM_052916	RNF157	ring finger protein 157
chr1_-_203916160	0.674		SLC45A3	solute carrier family 45, member 3
chr15_+_74416129	0.662		ISL2	ISL LIM homeobox 2
chr17_-_70690525	0.649		SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr15_+_39739933	0.642		MGA	MAX gene associated
chrX_+_38305634	0.635	NM_004615	TSPAN7	tetraspanin 7
chrX_-_132947290	0.632	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr15_+_74416156	0.629	NM_145805	ISL2	ISL LIM homeobox 2
chr3_-_13436802	0.628	NM_024923	NUP210	nucleoporin 210kDa
chr2_-_213111525	0.610	NM_001042599 NM_005235	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr17_-_70690625	0.610		SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr22_+_40702709	0.607	NM_019106 NM_145733	SEPT3	septin 3
chr20_+_51022352	0.606	NM_173485	TSHZ2	teashirt zinc finger homeobox 2
chr6_+_43846735	0.606		VEGFA	vascular endothelial growth factor A
chr21_+_34367747	0.603		MRPS6	mitochondrial ribosomal protein S6
chr17_-_70690664	0.601		SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr17_+_69939130	0.601	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr17_+_52026058	0.589	NM_005450	NOG	noggin
chr6_-_136652625	0.582	NM_001077440 NM_001077441 NM_014739	BCLAF1	BCL2-associated transcription factor 1
chr13_+_27392136	0.577	NM_000209	PDX1	pancreatic and duodenal homeobox 1
chr12_+_123023521	0.569	NM_152437	ZNF664	zinc finger protein 664
chr7_+_139523623	0.568		LOC100134229	hypothetical LOC100134229
chr4_-_113656762	0.563	NM_024019	NEUROG2	neurogenin 2
chr6_-_40663089	0.561	NM_020737	LRFN2	leucine rich repeat and fibronectin type III domain containing 2
chr7_-_105712646	0.556	NM_005746	NAMPT	nicotinamide phosphoribosyltransferase
chr8_+_85258257	0.553		RALYL	RALY RNA binding protein-like
chr15_+_81907176	0.552		SH3GL3	SH3-domain GRB2-like 3
chr15_+_24799174	0.552	NM_033223	GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr16_-_76026431	0.551	NM_199355	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr2_+_169021039	0.541	NM_203463	LASS6	LAG1 homolog, ceramide synthase 6
chr3_+_135996734	0.535	NM_004441	EPHB1	EPH receptor B1
chr12_-_22378833	0.530	NM_003034	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr5_+_151131655	0.529	NM_005754 NM_198395	G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr3_-_172660545	0.525	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr16_+_54782751	0.525	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_23850494	0.519	NM_001143919	LTB4R	leukotriene B4 receptor
chr13_-_20374895	0.516	NM_022459	XPO4	exportin 4
chr5_+_151131709	0.515		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr6_-_136652587	0.515		BCLAF1	BCL2-associated transcription factor 1
chr6_+_126112417	0.513	NM_012259	HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr15_+_39739864	0.510	NM_001080541 NM_001164273	MGA	MAX gene associated
chr1_+_60053050	0.510	NM_015888	HOOK1	hook homolog 1 (Drosophila)
chr8_-_105548323	0.508	NM_001385	DPYS	dihydropyrimidinase
chr1_-_50262203	0.508	NM_032785	AGBL4	ATP/GTP binding protein-like 4
chr7_+_138695537	0.502		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr9_+_86473273	0.502	NM_001018064 NM_006180	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr6_+_137285071	0.499	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr5_+_176170041	0.499	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr1_-_38285033	0.498	NM_002699	POU3F1	POU class 3 homeobox 1
chr7_+_113513828	0.494		FOXP2	forkhead box P2
chr6_+_34312667	0.494		HMGA1	high mobility group AT-hook 1
chrX_-_18282698	0.493	NM_006089	SCML2	sex comb on midleg-like 2 (Drosophila)
chr6_+_108593907	0.492	NM_003269	NR2E1	nuclear receptor subfamily 2, group E, member 1
chr1_+_226937732	0.491		RHOU	ras homolog gene family, member U
chr14_+_34413157	0.484
chr1_-_37991160	0.481		EPHA10	EPH receptor A10
chr6_-_10520264	0.481		TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_+_185171682	0.479		ZNF804A	zinc finger protein 804A
chr16_+_22733307	0.478	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr17_+_59429442	0.476	NM_001164257 NM_001191029 NM_001191030 NM_001191031	C17orf72	chromosome 17 open reading frame 72
chr17_-_70690688	0.473	NM_001005849 NM_006937	SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr9_-_101621964	0.471
chr5_+_138920893	0.469	NM_003339 NM_181838	UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr4_-_129428414	0.468		PGRMC2	progesterone receptor membrane component 2
chr7_+_24579239	0.466	NM_016447	MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr6_-_119712596	0.466	NM_005907	MAN1A1	mannosidase, alpha, class 1A, member 1
chr4_-_129428378	0.465		PGRMC2	progesterone receptor membrane component 2
chr8_+_126079929	0.464		SQLE	squalene epoxidase
chr17_-_37586716	0.463	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr22_-_17891777	0.456		CLDN5	claudin 5
chr1_-_203916239	0.449	NM_033102	SLC45A3	solute carrier family 45, member 3
chr15_-_66900309	0.444	NM_006305	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr3_+_135996990	0.441		EPHB1	EPH receptor B1
chr1_-_54076695	0.438	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr20_+_13924014	0.438	NM_080676	MACROD2	MACRO domain containing 2
chr16_+_22732982	0.437		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_+_151131707	0.436		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr3_+_6877812	0.435		GRM7	glutamate receptor, metabotropic 7
chr11_+_799985	0.433		RPLP2	ribosomal protein, large, P2
chr21_+_34367678	0.430	NM_032476 NM_006933	MRPS6 SLC5A3	mitochondrial ribosomal protein S6 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr3_+_4510160	0.428		ITPR1	inositol 1,4,5-triphosphate receptor, type 1
chr2_-_182253457	0.427	NM_002500	NEUROD1	neurogenic differentiation 1
chr8_+_126079900	0.426	NM_003129	SQLE	squalene epoxidase
chr2_+_32435800	0.425		BIRC6	baculoviral IAP repeat containing 6
chr2_+_32435550	0.423	NM_016252	BIRC6	baculoviral IAP repeat containing 6
chr2_-_219141199	0.422	NM_020935	USP37	ubiquitin specific peptidase 37
chr5_-_130528871	0.420		HINT1	histidine triad nucleotide binding protein 1
chr10_-_35970363	0.420	NM_031866	FZD8	frizzled homolog 8 (Drosophila)
chr10_+_23521464	0.418	NM_178161	PTF1A	pancreas specific transcription factor, 1a
chr13_+_99432258	0.415	NM_007129	ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)
chr2_+_181554048	0.415		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr17_+_6495694	0.414	NM_001105520	C17orf100	chromosome 17 open reading frame 100
chr4_-_152156314	0.414	NM_006726	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr9_+_4975243	0.411	NM_004972	JAK2	Janus kinase 2
chr16_-_65422365	0.407	NM_001018159 NM_001018160 NM_003905	NAE1	NEDD8 activating enzyme E1 subunit 1
chr15_+_38923914	0.406	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr2_+_30523586	0.406	NM_182551 NM_001002257	LCLAT1	lysocardiolipin acyltransferase 1
chr2_-_68332985	0.405	NM_000945	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha
chr15_+_38923470	0.405	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr12_-_55368323	0.405	NM_006601	PTGES3	prostaglandin E synthase 3 (cytosolic)
chr4_+_94969064	0.403	NM_005172	ATOH1	atonal homolog 1 (Drosophila)
chr3_+_214668	0.402
chr11_+_14621844	0.402	NM_000922	PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr20_-_1321744	0.401	NM_000801 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr22_-_17892001	0.400		CLDN5	claudin 5
chr4_-_83569572	0.399		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr5_-_81082614	0.397		SSBP2	single-stranded DNA binding protein 2
chr4_-_83569476	0.394		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr4_-_83569853	0.390		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr19_-_43089073	0.390	NM_031951	WDR87	WD repeat domain 87
chr2_+_185171480	0.389		ZNF804A	zinc finger protein 804A
chr1_-_12599934	0.388	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr20_+_13924263	0.387		MACROD2	MACRO domain containing 2
chr16_+_55684030	0.385		CPNE2	copine II
chr4_-_103968104	0.385	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr21_-_39642808	0.384		HMGN1	high-mobility group nucleosome binding domain 1
chr1_-_24179326	0.383		SRSF10	serine/arginine-rich splicing factor 10
chr2_+_26110232	0.382	NM_016131	RAB10	RAB10, member RAS oncogene family
chr9_-_139316523	0.380	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr8_+_69026895	0.378		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr9_+_99214190	0.377		TDRD7	tudor domain containing 7
chr2_+_198073257	0.375		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr6_+_99389300	0.373	NM_005604	POU3F2	POU class 3 homeobox 2
chr8_-_144887876	0.372	NM_198488	FAM83H	family with sequence similarity 83, member H
chr21_-_38954433	0.372		ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr17_+_50697319	0.372	NM_002126	HLF	hepatic leukemia factor
chr13_-_20374849	0.371		XPO4	exportin 4
chr9_+_99214000	0.370	NM_014290	TDRD7	tudor domain containing 7
chrX_+_70232362	0.370	NM_001170931 NM_005938	FOXO4	forkhead box O4
chr21_-_39642712	0.369		HMGN1	high-mobility group nucleosome binding domain 1
chr7_+_107171514	0.369	NM_024814	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr12_-_55368190	0.368		PTGES3	prostaglandin E synthase 3 (cytosolic)
chr21_-_39642935	0.365		HMGN1	high-mobility group nucleosome binding domain 1
chr1_-_54076521	0.364		TMEM48	transmembrane protein 48
chr2_-_99472843	0.362		REV1	REV1 homolog (S. cerevisiae)
chr17_+_25280999	0.362	NM_001145053	EFCAB5	EF-hand calcium binding domain 5
chr4_-_24641404	0.361	NM_018176	LGI2	leucine-rich repeat LGI family, member 2
chr8_+_110621485	0.360	NM_004215	EBAG9	estrogen receptor binding site associated, antigen, 9
chr7_+_138695144	0.356	NM_016019	LUC7L2	LUC7-like 2 (S. cerevisiae)
chr3_-_137953876	0.356	NM_005862	STAG1	stromal antigen 1
chr5_-_130998806	0.354	NM_001164386 NM_001164387 NM_001164388 NM_001164389 NM_001164390 NM_016340	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr5_+_169863601	0.352	NM_001034837 NM_014592	KCNIP1	Kv channel interacting protein 1
chr1_+_153366559	0.351		EFNA1	ephrin-A1
chr4_-_168392151	0.351		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr7_-_91601613	0.350		CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chr8_+_69027277	0.349		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr20_+_60130866	0.348	NM_144703	LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr4_-_105635499	0.345		CXXC4	CXXC finger protein 4
chr18_-_5533967	0.343	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr6_+_34312641	0.341		HMGA1	high mobility group AT-hook 1
chr6_+_126112431	0.340		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr7_-_72735665	0.340	NM_032317	DNAJC30	DnaJ (Hsp40) homolog, subfamily C, member 30
chr1_-_6182203	0.338	NM_000983	RPL22	ribosomal protein L22
chr4_+_82171142	0.336	NM_001201	BMP3	bone morphogenetic protein 3
chr9_-_124030770	0.335	NM_014368 NM_199160	LHX6	LIM homeobox 6
chr1_-_114855281	0.334	NM_015906 NM_033020	TRIM33	tripartite motif containing 33
chrX_-_54401161	0.334	NM_001002838 NM_020922	WNK3	WNK lysine deficient protein kinase 3
chrX_+_109132994	0.334	NM_032227	TMEM164	transmembrane protein 164
chr16_-_65422304	0.333		NAE1	NEDD8 activating enzyme E1 subunit 1
chr6_+_99389318	0.333		POU3F2	POU class 3 homeobox 2
chr5_-_139761182	0.333
chr2_-_171725150	0.332		TLK1	tousled-like kinase 1
chr3_+_14419066	0.331		SLC6A6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr16_+_23754772	0.331	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr4_-_152155827	0.331		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr17_-_70430839	0.331	NM_173477	USH1G	Usher syndrome 1G (autosomal recessive)
chr3_+_31998269	0.328	NM_001137674	ZNF860	zinc finger protein 860
chr7_-_50485515	0.328	NM_001042762 NM_022116	FIGNL1	fidgetin-like 1
chr1_+_111963920	0.327	NM_001010935 NM_002884	RAP1A	RAP1A, member of RAS oncogene family
chr9_+_86474393	0.327	NM_001018065 NM_001018066	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr8_+_110621092	0.326	NM_198120	EBAG9	estrogen receptor binding site associated, antigen, 9

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.29	2.46e-23	GO:0044237	cellular metabolic process
1.37	5.57e-22	GO:0044260	cellular macromolecule metabolic process
1.48	4.06e-20	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	1.17e-17	GO:0044238	primary metabolic process
1.40	2.63e-16	GO:0034641	cellular nitrogen compound metabolic process
1.38	1.99e-15	GO:0006807	nitrogen compound metabolic process
1.21	2.28e-15	GO:0008152	metabolic process
1.53	3.31e-15	GO:0010467	gene expression
1.13	1.15e-14	GO:0009987	cellular process
1.27	5.19e-14	GO:0043170	macromolecule metabolic process
1.45	3.60e-13	GO:0090304	nucleic acid metabolic process
1.48	5.09e-11	GO:0016070	RNA metabolic process
1.38	5.99e-11	GO:0044267	cellular protein metabolic process
1.36	2.29e-09	GO:0009058	biosynthetic process
1.36	2.49e-09	GO:0044249	cellular biosynthetic process
1.45	4.96e-09	GO:0034645	cellular macromolecule biosynthetic process
1.44	5.09e-09	GO:0009059	macromolecule biosynthetic process
1.27	2.56e-08	GO:0031323	regulation of cellular metabolic process
1.27	9.94e-08	GO:0060255	regulation of macromolecule metabolic process
1.95	2.15e-07	GO:0007420	brain development
1.32	2.24e-07	GO:0010468	regulation of gene expression
1.79	2.70e-07	GO:0007417	central nervous system development
1.24	6.60e-07	GO:0019222	regulation of metabolic process
1.66	1.73e-06	GO:0006396	RNA processing
1.42	1.83e-06	GO:0007399	nervous system development
1.25	1.84e-06	GO:0080090	regulation of primary metabolic process
1.32	1.95e-06	GO:0051252	regulation of RNA metabolic process
1.31	2.13e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.51	4.54e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.29	4.92e-06	GO:0031326	regulation of cellular biosynthetic process
1.30	5.07e-06	GO:0010556	regulation of macromolecule biosynthetic process
1.28	5.45e-06	GO:0009889	regulation of biosynthetic process
1.35	1.16e-05	GO:0006464	protein modification process
2.25	1.48e-05	GO:0030900	forebrain development
1.28	1.93e-05	GO:0071842	cellular component organization at cellular level
1.27	4.10e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	6.89e-05	GO:0043412	macromolecule modification
1.14	8.98e-05	GO:0050794	regulation of cellular process
1.26	9.76e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.59	1.10e-04	GO:0051276	chromosome organization
1.46	1.13e-04	GO:0032774	RNA biosynthetic process
1.24	1.24e-04	GO:0019538	protein metabolic process
1.12	1.64e-04	GO:0065007	biological regulation
1.29	2.36e-04	GO:0006355	regulation of transcription, DNA-dependent
1.67	2.39e-04	GO:0006325	chromatin organization
2.57	3.80e-04	GO:0021537	telencephalon development
1.33	4.23e-04	GO:0006996	organelle organization
1.72	4.63e-04	GO:0006397	mRNA processing
1.24	4.81e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.38	6.45e-04	GO:0009893	positive regulation of metabolic process
1.20	7.98e-04	GO:0032502	developmental process
1.80	8.37e-04	GO:0006412	translation
1.21	1.11e-03	GO:0016043	cellular component organization
1.57	1.42e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.12	1.43e-03	GO:0050789	regulation of biological process
1.45	1.51e-03	GO:0006351	transcription, DNA-dependent
1.59	1.96e-03	GO:0006753	nucleoside phosphate metabolic process
1.59	1.96e-03	GO:0009117	nucleotide metabolic process
1.64	2.54e-03	GO:0072521	purine-containing compound metabolic process
1.69	2.85e-03	GO:0016568	chromatin modification
1.21	3.44e-03	GO:0048856	anatomical structure development
1.19	4.82e-03	GO:0071840	cellular component organization or biogenesis
1.22	5.93e-03	GO:0048731	system development
1.36	6.22e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.70	6.44e-03	GO:0009259	ribonucleotide metabolic process
1.48	6.65e-03	GO:0010628	positive regulation of gene expression
1.64	8.79e-03	GO:0006163	purine nucleotide metabolic process
1.72	8.99e-03	GO:0009141	nucleoside triphosphate metabolic process
1.54	9.17e-03	GO:0016071	mRNA metabolic process
1.50	9.66e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	9.75e-03	GO:0031325	positive regulation of cellular metabolic process
1.27	1.17e-02	GO:0044281	small molecule metabolic process
1.55	1.37e-02	GO:0019226	transmission of nerve impulse
1.55	1.37e-02	GO:0035637	multicellular organismal signaling
1.92	1.43e-02	GO:0016569	covalent chromatin modification
1.71	1.45e-02	GO:0009144	purine nucleoside triphosphate metabolic process
1.48	1.71e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.46	1.79e-02	GO:0051254	positive regulation of RNA metabolic process
1.48	1.83e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.92	2.00e-02	GO:0016570	histone modification
1.24	2.36e-02	GO:0048523	negative regulation of cellular process
1.67	2.41e-02	GO:0009150	purine ribonucleotide metabolic process
1.53	2.50e-02	GO:0034621	cellular macromolecular complex subunit organization
1.51	2.57e-02	GO:0051253	negative regulation of RNA metabolic process
1.18	2.59e-02	GO:0007275	multicellular organismal development
1.43	2.66e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.77	2.71e-02	GO:0050767	regulation of neurogenesis
1.57	2.80e-02	GO:0007268	synaptic transmission
1.19	3.14e-02	GO:0051234	establishment of localization
1.39	3.17e-02	GO:0009891	positive regulation of biosynthetic process
1.62	3.41e-02	GO:0051301	cell division
1.19	3.77e-02	GO:0006810	transport
1.68	3.90e-02	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.39	4.24e-02	GO:0048699	generation of neurons
1.38	4.27e-02	GO:0031324	negative regulation of cellular metabolic process
1.68	4.42e-02	GO:0009199	ribonucleoside triphosphate metabolic process
1.17	4.43e-02	GO:0051179	localization
1.70	4.45e-02	GO:0010608	posttranscriptional regulation of gene expression
1.39	4.52e-02	GO:0031328	positive regulation of cellular biosynthetic process
1.31	4.60e-02	GO:0051641	cellular localization
1.22	4.68e-02	GO:0048519	negative regulation of biological process
2.37	4.75e-02	GO:0021953	central nervous system neuron differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.15	4.42e-27	GO:0005622	intracellular
1.15	4.52e-26	GO:0044424	intracellular part
1.19	7.10e-21	GO:0043231	intracellular membrane-bounded organelle
1.19	8.03e-21	GO:0043227	membrane-bounded organelle
1.29	1.06e-20	GO:0005634	nucleus
1.16	2.61e-19	GO:0043226	organelle
1.16	3.66e-19	GO:0043229	intracellular organelle
1.15	2.18e-10	GO:0005737	cytoplasm
1.38	2.58e-10	GO:0044428	nuclear part
1.37	5.06e-10	GO:0070013	intracellular organelle lumen
1.36	6.58e-10	GO:0031974	membrane-enclosed lumen
1.40	3.78e-09	GO:0031981	nuclear lumen
1.35	4.21e-09	GO:0043233	organelle lumen
1.48	5.43e-09	GO:0005654	nucleoplasm
1.05	2.68e-08	GO:0044464	cell part
1.05	2.83e-08	GO:0005623	cell
1.63	5.07e-08	GO:0044451	nucleoplasm part
1.18	7.03e-08	GO:0044446	intracellular organelle part
1.17	3.26e-07	GO:0044422	organelle part
1.22	7.01e-06	GO:0032991	macromolecular complex
1.65	1.32e-05	GO:0030529	ribonucleoprotein complex
1.13	3.23e-04	GO:0044444	cytoplasmic part
4.43	7.03e-04	GO:0031519	PcG protein complex
1.72	1.22e-02	GO:0000785	chromatin
2.60	1.48e-02	GO:0034708	methyltransferase complex
2.60	1.48e-02	GO:0035097	histone methyltransferase complex
5.45	1.76e-02	GO:0035098	ESC/E(Z) complex
3.89	2.67e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.18	2.73e-02	GO:0043228	non-membrane-bounded organelle
1.18	2.73e-02	GO:0043232	intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.37	2.13e-16	GO:0003676	nucleic acid binding
1.41	8.45e-13	GO:0000166	nucleotide binding
1.72	3.96e-12	GO:0003723	RNA binding
1.10	8.96e-11	GO:0005488	binding
1.16	4.72e-09	GO:0005515	protein binding
1.53	5.75e-08	GO:0030528	transcription regulator activity
1.33	5.64e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.33	6.41e-06	GO:0017076	purine nucleotide binding
1.32	1.10e-05	GO:0032553	ribonucleotide binding
1.32	1.10e-05	GO:0032555	purine ribonucleotide binding
1.27	6.80e-05	GO:0003677	DNA binding
1.33	2.04e-04	GO:0030554	adenyl nucleotide binding
1.30	2.16e-04	GO:0016740	transferase activity
1.32	3.13e-04	GO:0005524	ATP binding
1.32	3.89e-04	GO:0032559	adenyl ribonucleotide binding
1.39	3.20e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.36	4.24e-03	GO:0001071	nucleic acid binding transcription factor activity
1.36	4.24e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.41	6.98e-03	GO:0019899	enzyme binding
1.40	8.36e-03	GO:0016301	kinase activity