Motif ID: LHX3,4.p2

Z-value: 1.230


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LHX3chr9_-_1382347070.467.2e-02Click!
LHX4chr1_+_1784660640.116.7e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_57209319 1.696 NM_003865
 HESX1
HESX homeobox 1
chr13_-_83354425 1.164 SLITRK1
SLIT and NTRK-like family, member 1
chr13_+_112349358 1.156 NM_207440
 C13orf35
chromosome 13 open reading frame 35
chr9_-_137671206 1.120 NM_182974
 GLT6D1
glycosyltransferase 6 domain containing 1
chr7_-_25234582 1.048 NM_022150
 NPVF
neuropeptide VF precursor
chr22_+_38627031 1.007 NM_004810
 GRAP2
GRB2-related adaptor protein 2
chr19_-_56612653 0.957 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
 SIGLEC10






sialic acid binding Ig-like lectin 10






chr11_-_30910074 0.940 NM_020869
 DCDC5
doublecortin domain containing 5
chr4_+_68995761 0.887 NM_014058
 TMPRSS11E
transmembrane protease, serine 11E
chr4_-_189263395 0.859 NM_173553
 TRIML2
tripartite motif family-like 2
chr7_-_36991189 0.851 NM_001039459
 ELMO1
engulfment and cell motility 1
chr4_+_119174947 0.836 NM_004784
 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_-_1935764 0.827 NM_016358
 IRX4
iroquois homeobox 4
chr18_-_13905534 0.811 NM_000529
 MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr1_+_196874839 0.810 PTPRC
protein tyrosine phosphatase, receptor type, C
chr16_+_11966464 0.795 NM_001192
 TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr18_+_59767567 0.779 NM_001123366
 HMSD
histocompatibility (minor) serpin domain containing
chr2_-_99238001 0.718 NM_175735
 LYG2
lysozyme G-like 2
chr6_+_132915522 0.716 NM_053278
 TAAR8
trace amine associated receptor 8
chr11_-_102081654 0.713 NM_022122
 MMP27
matrix metallopeptidase 27

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.77 1.80e-08 GO:0007608 sensory perception of smell
2.57 1.46e-07 GO:0007606 sensory perception of chemical stimulus
2.01 8.36e-06 GO:0007600 sensory perception
1.78 6.75e-03 GO:0006952 defense response
1.72 4.48e-05 GO:0050877 neurological system process
1.66 9.68e-06 GO:0003008 system process
1.34 1.33e-06 GO:0032501 multicellular organismal process
1.23 1.69e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.52 3.61e-05 GO:0005576 extracellular region
1.42 1.35e-08 GO:0005886 plasma membrane
1.41 2.42e-08 GO:0071944 cell periphery
1.35 6.70e-09 GO:0016021 integral to membrane
1.34 2.05e-08 GO:0031224 intrinsic to membrane
1.25 1.99e-05 GO:0044425 membrane part
1.16 9.16e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
7.22 8.76e-04 GO:0001608 nucleotide receptor activity, G-protein coupled
7.22 8.76e-04 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
5.64 8.78e-03 GO:0001614 purinergic nucleotide receptor activity
5.64 8.78e-03 GO:0016502 nucleotide receptor activity
5.01 2.46e-02 GO:0035586 purinergic receptor activity
2.90 6.98e-10 GO:0004984 olfactory receptor activity
2.37 2.19e-12 GO:0004930 G-protein coupled receptor activity
1.97 3.19e-10 GO:0004888 transmembrane receptor activity
1.81 4.63e-10 GO:0004872 receptor activity
1.59 8.59e-07 GO:0004871 signal transducer activity
1.59 8.59e-07 GO:0060089 molecular transducer activity