Motif ID: T.p2

Z-value: 0.739


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Tchr6_-_1665021190.759.2e-04Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_123339662 0.882 NM_181709
FAM101A
family with sequence similarity 101, member A
chr12_-_51360439 0.777 NM_006121
KRT1
keratin 1
chr17_+_18320822 0.765 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chrX_-_106033202 0.732 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr12_-_51153788 0.725 NM_173086
KRT6C
keratin 6C
chrX_+_128741562 0.637 NM_018990
SASH3
SAM and SH3 domain containing 3
chr11_+_117452936 0.583 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr1_-_199259133 0.573 KIF21B
kinesin family member 21B
chr11_-_55815113 0.569 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr1_+_208008517 0.551 TRAF3IP3
TRAF3 interacting protein 3
chr2_+_176680251 0.549 NM_021192
HOXD11
homeobox D11
chr7_-_123460722 0.510 NM_001136002
TMEM229A
transmembrane protein 229A
chrX_+_128741578 0.463 SASH3
SAM and SH3 domain containing 3
chr1_+_34997928 0.457 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr2_-_100088760 0.451 AFF3
AF4/FMR2 family, member 3
chr17_+_3065661 0.439 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr7_+_142723340 0.430 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr15_-_88095363 0.417 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr17_-_20311411 0.406 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr17_-_40858775 0.377 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr11_+_93394025 0.377 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_151296611 0.353 NM_005988
SPRR2A
small proline-rich protein 2A
chr10_+_44726635 0.342 NM_001123376
TMEM72
transmembrane protein 72
chr1_+_100777044 0.342 GPR88
G protein-coupled receptor 88
chr2_-_218739891 0.330 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr12_-_51132129 0.329 NM_005555
KRT6B
keratin 6B
chr3_-_52419056 0.326 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr9_-_37024358 0.326 NM_016734
PAX5
paired box 5
chr11_-_7804094 0.323 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr2_-_215711313 0.320 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr16_+_56211150 0.309 GPR56
G protein-coupled receptor 56
chr4_+_154083584 0.306 NM_033393
FHDC1
FH2 domain containing 1
chr19_-_13808101 0.278 LOC284454
hypothetical LOC284454
chr3_-_52419086 0.278 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr17_-_59304729 0.277 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr22_-_49363209 0.276 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr3_+_47004457 0.271 NBEAL2
neurobeachin-like 2
chr17_+_31455332 0.271 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr1_+_15935395 0.267 NM_207348
SLC25A34
solute carrier family 25, member 34
chr3_-_52418933 0.262 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr20_+_42776888 0.258 WISP2
WNT1 inducible signaling pathway protein 2
chr21_-_30791298 0.257 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr6_-_130578110 0.250 NM_152552
SAMD3
sterile alpha motif domain containing 3
chrX_+_152423277 0.249 BGN
biglycan
chr8_-_145132582 0.248 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr1_+_246718487 0.243 NM_001004697
OR2T5
olfactory receptor, family 2, subfamily T, member 5
chr11_-_119514058 0.242 NM_012101
TRIM29
tripartite motif containing 29
chr17_+_22982372 0.242 LGALS9
lectin, galactoside-binding, soluble, 9
chr4_+_74937876 0.241 NM_002620
PF4V1
platelet factor 4 variant 1
chr2_+_234265059 0.240 NM_205862
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chrX_-_18600108 0.238 NM_000330
RS1
retinoschisin 1
chr10_-_98935369 0.237 SLIT1
slit homolog 1 (Drosophila)
chr17_-_37560541 0.232 NM_004583
NM_201434
RAB5C

RAB5C, member RAS oncogene family

chr11_-_110755112 0.223 POU2AF1
POU class 2 associating factor 1
chr17_+_22982278 0.220 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr2_-_151854619 0.216 NM_004688
NMI
N-myc (and STAT) interactor
chr1_-_246804680 0.215 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr12_-_7739591 0.208 NM_020634
GDF3
growth differentiation factor 3
chr17_-_37560461 0.207 RAB5C
RAB5C, member RAS oncogene family
chr17_+_22982319 0.205 LGALS9
lectin, galactoside-binding, soluble, 9
chr7_+_72913424 0.204 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr17_+_41278035 0.203 NM_175882
IMP5
intramembrane protease 5
chr12_+_112107747 0.203 NM_032848
C12orf52
chromosome 12 open reading frame 52
chr14_-_23878871 0.202 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr17_+_22982383 0.201 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_+_55896844 0.199 NM_007224
NXPH4
neurexophilin 4
chr1_-_117011824 0.199 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr21_+_42364494 0.197 NM_001004416
NM_173568
UMODL1

uromodulin-like 1

chr17_+_22982344 0.194 LGALS9
lectin, galactoside-binding, soluble, 9
chr1_-_203557379 0.193 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr5_+_176717553 0.192


chr12_-_54646061 0.188 NM_006928
PMEL
premelanosome protein
chr1_-_246789396 0.184 NM_001004694
OR2T29
OR2T5
olfactory receptor, family 2, subfamily T, member 29
olfactory receptor, family 2, subfamily T, member 5
chr5_-_14706486 0.184


chr17_-_59349867 0.184 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr1_-_37272295 0.180 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr19_-_19245177 0.177


chr17_+_7474177 0.177 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr13_-_29067795 0.175 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_-_18455207 0.174 NM_001131010
SATB1
SATB homeobox 1
chr7_-_87687302 0.170 NM_003130
SRI
sorcin
chr7_+_121300394 0.169 NM_002851
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr19_+_60279032 0.167 NM_133180
EPS8L1
EPS8-like 1
chr2_+_222871109 0.165 NM_153038
CCDC140
coiled-coil domain containing 140
chr7_-_16471817 0.164 NM_015464
SOSTDC1
sclerostin domain containing 1
chr19_+_7734034 0.162 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr7_-_36730525 0.162 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr2_-_68952006 0.161 NM_014482
BMP10
bone morphogenetic protein 10
chr7_+_121300446 0.156 PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr6_-_33787479 0.156 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr11_-_65869113 0.153 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr15_-_38417564 0.151 C15orf52
chromosome 15 open reading frame 52
chr12_-_1791146 0.149 CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr22_+_48870434 0.148 NM_001164104
NM_018995
MOV10L1

Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)

chr7_-_44195405 0.148 NM_000162
GCK
glucokinase (hexokinase 4)
chr19_+_54776398 0.148 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr1_-_114215768 0.148 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr19_+_59973074 0.148 NM_014218
KIR2DS2
KIR2DL1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr1_+_66570363 0.146 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_-_14717703 0.146 LOC728178
hypothetical protein LOC728178
chr3_+_10832867 0.146 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr19_-_17236522 0.146 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr12_-_51383513 0.145 NM_175078
KRT77
keratin 77
chr9_-_14712669 0.144 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chrX_+_90976314 0.144 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr17_+_8154864 0.143 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr1_-_154536051 0.137 NM_001004319
VHLL
von Hippel-Lindau tumor suppressor-like
chr7_-_5536704 0.134 NM_001101
ACTB
actin, beta
chr21_+_24722913 0.132 FLJ42200
FLJ42200 protein
chr5_-_177031780 0.128 LOC202181
hypothetical LOC202181
chr6_+_132915522 0.127 NM_053278
TAAR8
trace amine associated receptor 8
chr1_+_559618 0.126


chr11_+_89032112 0.126 NM_153696
FOLH1B
folate hydrolase 1B
chr17_-_59342319 0.125 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr14_-_73095396 0.125 NM_203309
HEATR4
HEAT repeat containing 4
chr15_+_58083798 0.125 FOXB1
forkhead box B1
chr6_+_49575629 0.124 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr4_-_5762175 0.124 NM_001166136
EVC2
Ellis van Creveld syndrome 2
chr11_+_55700669 0.123 NM_001005492
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chrX_-_84250629 0.123 NM_001012980
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr1_-_13546097 0.123 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr2_-_31491057 0.122 XDH
xanthine dehydrogenase
chr1_+_17404206 0.122 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr14_+_66725862 0.121 NM_173526
FAM71D
family with sequence similarity 71, member D
chr15_-_38387266 0.121 PLCB2
phospholipase C, beta 2
chr7_-_5536783 0.121 ACTB
actin, beta
chr6_-_109869066 0.120 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr3_-_62836052 0.119 NM_003716
NM_183393
NM_183394
CADPS


Ca++-dependent secretion activator


chr10_-_76538859 0.117 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr1_+_12958129 0.117 NM_001100631
PRAMEF22
PRAME family member 22
chr3_-_57653634 0.116 NM_152678
FAM116A
family with sequence similarity 116, member A
chr18_-_27594696 0.114 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr1_+_173111306 0.113 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr10_+_118295417 0.112 NM_000936
PNLIP
pancreatic lipase
chrX_-_62564934 0.111 LOC92249
hypothetical LOC92249
chr11_+_122214415 0.111 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr15_+_58083712 0.110 NM_012182
FOXB1
forkhead box B1
chr7_-_99365178 0.109 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr8_+_22518477 0.108 NM_021174
KIAA1967
KIAA1967
chr11_-_62445587 0.108 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr19_+_17723285 0.102 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr15_-_38387317 0.102 PLCB2
phospholipase C, beta 2
chrX_+_106048245 0.101 NM_001171095
CLDN2
claudin 2
chr3_-_48573556 0.099 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr6_+_83129641 0.098 NM_006670
TPBG
trophoblast glycoprotein
chr21_-_33107813 0.097 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr17_-_58877276 0.097 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr17_+_45706786 0.096 NM_153229
TMEM92
transmembrane protein 92
chr1_+_246591505 0.096 NM_001004696
OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr19_-_14121728 0.094 LPHN1
latrophilin 1
chr11_-_7775064 0.094 NM_153444
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chrX_+_17303727 0.093 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr17_+_3047559 0.093 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr7_-_149101227 0.093 NM_207336
ZNF467
zinc finger protein 467
chr12_-_51065629 0.092 NM_033045
KRT84
keratin 84
chr4_-_145281237 0.092 NM_002099
GYPA
glycophorin A (MNS blood group)
chr10_-_105228986 0.091 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr6_-_49862858 0.091 NM_138733
PGK2
phosphoglycerate kinase 2
chr5_+_1278469 0.089 NM_182632
SLC6A18
solute carrier family 6, member 18
chr3_+_38282301 0.089 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr7_+_30758269 0.088 NM_006774
INMT-FAM188B
INMT
INMT-FAM188B read-through transcript
indolethylamine N-methyltransferase
chr12_-_52827275 0.088


chr2_+_233029076 0.088 NM_001631
ALPI
alkaline phosphatase, intestinal
chr17_+_8154280 0.086 NM_173728
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr7_+_99865340 0.086 MEPCE
methylphosphate capping enzyme
chr20_+_35406497 0.086 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chrX_-_8729377 0.085 NM_001171186
NM_174951
FAM9A

family with sequence similarity 9, member A

chr20_-_54013418 0.085 NM_080617
CBLN4
cerebellin 4 precursor
chr7_-_80386258 0.084 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr19_-_60458915 0.083 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr10_-_123346148 0.083 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr1_+_32992131 0.082


chr16_+_11966464 0.082 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chrX_-_102234606 0.081 NM_022052
NXF3
nuclear RNA export factor 3
chr18_-_72857951 0.081 MBP
myelin basic protein
chrX_+_102749489 0.081 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr11_-_110917632 0.079


chr17_-_59327602 0.079 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr11_-_93223315 0.079 NM_001144871
C11orf90
chromosome 11 open reading frame 90
chr12_-_84754289 0.077 NM_005447
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr12_+_21417068 0.077 NM_000415
IAPP
islet amyloid polypeptide
chr1_+_154389945 0.077 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr1_-_110949867 0.077 NM_004974
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr13_-_24644304 0.076 FAM123A
family with sequence similarity 123A
chr20_+_42777298 0.076 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr7_-_87687276 0.076 SRI
sorcin
chr11_+_59612712 0.075 NM_000139
MS4A2
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
chr11_+_26972244 0.075 FIBIN
fin bud initiation factor homolog (zebrafish)
chrX_+_74410774 0.074


chr19_-_48976852 0.074 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr5_-_146415782 0.074 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr19_-_17819773 0.074 JAK3
Janus kinase 3
chr19_-_63556632 0.073 NM_130786
A1BG
alpha-1-B glycoprotein
chr15_+_38648801 0.073 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr18_-_72858037 0.073 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr2_+_33514896 0.072 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_+_2240996 0.072


chr5_-_34020445 0.071 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr17_-_37560514 0.070 RAB5C
RAB5C, member RAS oncogene family
chr11_+_123945102 0.070 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 7.32e-03 GO:0032501 multicellular organismal process
1.84 1.00e-02 GO:0003008 system process
1.95 1.26e-02 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 4.69e-04 GO:0016021 integral to membrane
1.38 1.39e-03 GO:0031224 intrinsic to membrane
1.45 3.22e-03 GO:0005886 plasma membrane
1.70 3.98e-03 GO:0005576 extracellular region
1.43 6.05e-03 GO:0071944 cell periphery
1.30 1.27e-02 GO:0044425 membrane part
1.25 1.91e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.80 3.66e-04 GO:0004871 signal transducer activity
1.80 3.66e-04 GO:0060089 molecular transducer activity
1.83 2.20e-03 GO:0004872 receptor activity
1.85 2.46e-02 GO:0004888 transmembrane receptor activity
2.05 4.03e-02 GO:0004930 G-protein coupled receptor activity