Motif ID: FOXP3.p2

Z-value: 0.614


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_49008115-0.039.2e-01Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_17563186 1.950 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr9_-_70780574 1.549


chrX_-_100527799 1.271 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr5_+_137447479 0.891 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr14_+_19655405 0.821 NM_001004715
OR4K17
olfactory receptor, family 4, subfamily K, member 17
chr6_-_6632197 0.771


chr1_+_183970093 0.763 NM_031935
HMCN1
hemicentin 1
chr12_+_10054492 0.757 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chrX_+_92815667 0.734 NM_001171109
NM_001171110
NM_001171111
NM_173698
FAM133A



family with sequence similarity 133, member A



chr12_-_10479810 0.720 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr6_-_154719560 0.683 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr3_-_19950675 0.656 NM_144715
EFHB
EF-hand domain family, member B
chr11_+_55343658 0.617 NM_001001952
OR5D18
olfactory receptor, family 5, subfamily D, member 18
chr7_+_29840865 0.581 NM_001080529
WIPF3
WAS/WASL interacting protein family, member 3
chr17_-_3283884 0.576 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr2_-_158008763 0.574 NM_004288
CYTIP
cytohesin 1 interacting protein
chr21_-_33107813 0.565 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_109201228 0.513 NM_152763
AKNAD1
AKNA domain containing 1
chr4_+_70180805 0.511 NM_053039
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr3_+_133518900 0.509 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
7.42 4.58e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
7.07 1.82e-02 GO:0006956 complement activation
5.47 4.54e-02 GO:0072376 protein activation cascade
5.10 1.22e-02 GO:0006959 humoral immune response
4.80 6.49e-04 GO:0042742 defense response to bacterium
4.41 2.21e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.27 1.52e-13 GO:0007608 sensory perception of smell
4.24 3.29e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.82 9.92e-12 GO:0007606 sensory perception of chemical stimulus
3.70 6.13e-06 GO:0050778 positive regulation of immune response
3.63 4.14e-02 GO:0002252 immune effector process
3.48 1.64e-03 GO:0002253 activation of immune response
3.06 8.72e-06 GO:0050776 regulation of immune response
2.95 3.35e-02 GO:0009617 response to bacterium
2.82 2.55e-04 GO:0002684 positive regulation of immune system process
2.70 2.84e-08 GO:0006952 defense response
2.57 2.92e-02 GO:0045087 innate immune response
2.45 4.87e-06 GO:0007600 sensory perception
2.32 2.99e-04 GO:0006955 immune response
2.11 2.40e-02 GO:0002682 regulation of immune system process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.98 4.93e-10 GO:0005576 extracellular region
1.97 5.39e-03 GO:0005615 extracellular space
1.71 4.78e-02 GO:0044421 extracellular region part
1.62 3.70e-10 GO:0005886 plasma membrane
1.61 3.09e-10 GO:0071944 cell periphery
1.46 3.09e-08 GO:0016021 integral to membrane
1.45 2.87e-08 GO:0031224 intrinsic to membrane
1.34 4.95e-06 GO:0044425 membrane part
1.25 2.09e-04 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
6.49 2.57e-02 GO:0003823 antigen binding
4.38 3.06e-14 GO:0004984 olfactory receptor activity
2.83 5.52e-11 GO:0004930 G-protein coupled receptor activity
2.65 1.15e-14 GO:0004888 transmembrane receptor activity
2.29 3.87e-13 GO:0004872 receptor activity
1.99 4.36e-10 GO:0004871 signal transducer activity
1.99 4.36e-10 GO:0060089 molecular transducer activity