Motif ID: CREB1.p2

Z-value: 1.020


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081029370.292.7e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_171558188 2.377 SKIL
SKI-like oncogene
chr3_+_171558215 2.301 SKIL
SKI-like oncogene
chr15_-_53487748 2.184 NM_004748
NM_020739
 CCPG1

cell cycle progression 1

chr17_+_54997667 2.113 NM_001166301
NM_024612
 DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr3_+_171558143 1.839 NM_001145098
NM_005414
 SKIL

SKI-like oncogene

chr11_+_113776582 1.781 NM_016090
 RBM7
RNA binding motif protein 7
chr17_+_15843832 1.741 TTC19
tetratricopeptide repeat domain 19
chr4_+_153676857 1.667 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr4_-_186584031 1.652 NM_018359
 UFSP2
UFM1-specific peptidase 2
chr1_+_110328830 1.570 NM_006621
 AHCYL1
adenosylhomocysteinase-like 1
chr11_-_28086263 1.478 KIF18A
kinesin family member 18A
chr8_-_17148474 1.441 CNOT7
CCR4-NOT transcription complex, subunit 7
chr1_+_110328955 1.406 AHCYL1
adenosylhomocysteinase-like 1
chr9_-_124066901 1.360 NM_033117
 RBM18
RNA binding motif protein 18
chr17_-_8092078 1.359 CTC1
CTS telomere maintenance complex component 1
chr19_+_58750305 1.342 NM_001079907
 ZNF331
zinc finger protein 331
chr8_-_17148637 1.321 NM_013354
NM_054026
 CNOT7

CCR4-NOT transcription complex, subunit 7

chr7_-_158314963 1.307 NM_020728
 ESYT2
extended synaptotagmin-like protein 2
chr7_+_151353707 1.306 NM_022087
 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr10_+_85889164 1.306 NM_014394
 GHITM
growth hormone inducible transmembrane protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 82 entries
enrichment   p-value GO term description
6.15 3.27e-02 GO:0051310 metaphase plate congression
3.53 7.10e-07 GO:0051028 mRNA transport
3.44 4.08e-07 GO:0050657 nucleic acid transport
3.44 4.08e-07 GO:0050658 RNA transport
3.44 4.08e-07 GO:0051236 establishment of RNA localization
3.33 1.06e-06 GO:0006403 RNA localization
3.11 5.09e-03 GO:0051656 establishment of organelle localization
3.05 6.84e-06 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.71 1.39e-02 GO:0000086 G2/M transition of mitotic cell cycle
2.60 1.28e-02 GO:0051789 response to protein stimulus
2.57 3.65e-02 GO:0051640 organelle localization
2.52 1.63e-02 GO:0048193 Golgi vesicle transport
2.50 1.96e-04 GO:0000375 RNA splicing, via transesterification reactions
2.50 2.83e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.50 2.83e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
2.30 1.93e-05 GO:0000087 M phase of mitotic cell cycle
2.30 1.93e-05 GO:0008380 RNA splicing
2.28 5.15e-05 GO:0000280 nuclear division
2.28 5.15e-05 GO:0007067 mitosis
2.24 1.15e-07 GO:0000279 M phase

Gene overrepresentation in compartment category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
3.03 1.26e-02 GO:0005643 nuclear pore
2.96 6.28e-03 GO:0071013 catalytic step 2 spliceosome
2.68 3.53e-04 GO:0005681 spliceosomal complex
2.67 4.53e-02 GO:0046930 pore complex
2.62 3.68e-02 GO:0000776 kinetochore
2.58 5.44e-04 GO:0000775 chromosome, centromeric region
2.28 2.57e-02 GO:0000793 condensed chromosome
2.18 1.36e-03 GO:0016604 nuclear body
2.05 2.88e-08 GO:0005694 chromosome
2.05 1.97e-07 GO:0005730 nucleolus
2.03 2.91e-21 GO:0005654 nucleoplasm
1.97 1.10e-05 GO:0044427 chromosomal part
1.95 1.13e-03 GO:0005815 microtubule organizing center
1.95 4.84e-02 GO:0005813 centrosome
1.94 1.48e-25 GO:0031981 nuclear lumen
1.89 5.52e-08 GO:0044451 nucleoplasm part
1.88 6.77e-28 GO:0044428 nuclear part
1.83 1.41e-04 GO:0030529 ribonucleoprotein complex
1.77 3.05e-22 GO:0070013 intracellular organelle lumen
1.74 3.91e-21 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
2.69 6.34e-03 GO:0008026 ATP-dependent helicase activity
2.69 6.34e-03 GO:0070035 purine NTP-dependent helicase activity
2.49 3.49e-03 GO:0004386 helicase activity
1.97 7.18e-11 GO:0003723 RNA binding
1.87 7.18e-03 GO:0016887 ATPase activity
1.58 2.66e-03 GO:0016462 pyrophosphatase activity
1.58 3.16e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.58 5.32e-03 GO:0017111 nucleoside-triphosphatase activity
1.57 3.74e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.48 3.64e-05 GO:0005524 ATP binding
1.46 1.04e-04 GO:0032559 adenyl ribonucleotide binding
1.45 1.04e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.45 1.50e-04 GO:0030554 adenyl nucleotide binding
1.44 2.78e-07 GO:0000166 nucleotide binding
1.42 3.80e-05 GO:0032553 ribonucleotide binding
1.42 3.80e-05 GO:0032555 purine ribonucleotide binding
1.42 5.86e-05 GO:0017076 purine nucleotide binding
1.39 3.66e-09 GO:0003676 nucleic acid binding
1.34 1.33e-02 GO:0016740 transferase activity
1.26 8.31e-08 GO:0003824 catalytic activity