Motif ID: ZNF423.p2

Z-value: 2.084


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_484184180.302.6e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_35017691 2.126 NM_006160
NEUROD2
neurogenic differentiation 2
chr19_+_14405100 1.765 NM_002741
PKN1
protein kinase N1
chr19_-_4054200 1.709 MAP2K2
mitogen-activated protein kinase kinase 2
chr3_-_129024665 1.693 NM_001003794
MGLL
monoglyceride lipase
chr19_-_4017739 1.650 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr9_+_135880363 1.590 NCRNA00094
non-protein coding RNA 94
chr11_-_68537243 1.550 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr19_+_50663089 1.503 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr7_+_99919485 1.402 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr22_+_44828338 1.372


chr19_+_49943773 1.349 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr11_+_72696963 1.349 ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr2_+_121271336 1.334 NM_005270
GLI2
GLI family zinc finger 2
chr17_-_35017650 1.278 NEUROD2
neurogenic differentiation 2
chr5_+_170668892 1.274 NM_021025
TLX3
T-cell leukemia homeobox 3
chr19_-_11406900 1.263 NM_145045
CCDC151
coiled-coil domain containing 151
chr19_-_11550765 1.263 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr17_+_74531873 1.235 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_+_18391423 1.205


chr9_-_130526192 1.201 NM_032799
ZDHHC12
zinc finger, DHHC-type containing 12
chr20_+_762355 1.194 NM_001042353
FAM110A
family with sequence similarity 110, member A
chr11_-_67028415 1.179 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr11_+_1925162 1.172 MRPL23
mitochondrial ribosomal protein L23
chr19_+_4423149 1.169 NM_001001520
NM_032631
HDGFRP2

hepatoma-derived growth factor-related protein 2

chr11_+_65792603 1.168 NM_030981
RAB1B
RAB1B, member RAS oncogene family
chr2_+_100087812 1.166


chr10_-_134940315 1.140 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr19_+_7506632 1.126 PNPLA6
patatin-like phospholipase domain containing 6
chr19_-_1993022 1.122 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_+_176717449 1.118 NM_006480
RGS14
regulator of G-protein signaling 14
chr19_-_1992862 1.106 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr14_+_23907065 1.102 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr9_+_134027154 1.090 NM_032536
NTNG2
netrin G2
chr17_+_2187545 1.066 NM_014853
NM_001098509
SGSM2

small G protein signaling modulator 2

chr11_-_44928803 1.048 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr19_-_4351357 1.023 SH3GL1
SH3-domain GRB2-like 1
chr5_-_1498510 1.013 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr11_+_834111 0.991 TSPAN4
tetraspanin 4
chr17_+_74531820 0.979 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr9_-_90983195 0.972 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr16_+_639278 0.971 NM_145294
WDR90
WD repeat domain 90
chr11_+_72697310 0.964 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr5_+_86599575 0.961


chr12_-_119038941 0.954 RAB35
RAB35, member RAS oncogene family
chr16_-_3131348 0.952


chr19_+_43089720 0.949 SIPA1L3
signal-induced proliferation-associated 1 like 3
chr8_-_80842452 0.947 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr11_+_60448487 0.946 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr16_+_66236512 0.936 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr19_-_18409971 0.931 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr19_-_54005916 0.925 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr19_-_10281220 0.921 NM_001103167
ZGLP1
zinc finger, GATA-like protein 1
chr2_+_218833982 0.920 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr19_+_43089681 0.919 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr19_+_18391211 0.916 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr11_+_61352209 0.916 NM_004265
FADS2
fatty acid desaturase 2
chr12_+_48303607 0.902 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_+_14405216 0.902 PKN1
protein kinase N1
chr19_-_18409788 0.896 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr9_-_16860664 0.887 BNC2
basonuclin 2
chr17_-_8711701 0.883 NM_001010855
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr19_-_4351470 0.883 NM_003025
SH3GL1
SH3-domain GRB2-like 1
chr19_-_41083288 0.882 NM_139239
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr12_-_119038995 0.880 NM_001167606
NM_006861
RAB35

RAB35, member RAS oncogene family

chr11_+_61352348 0.872 FADS2
fatty acid desaturase 2
chr19_-_56303434 0.864 NM_145232
CTU1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr7_-_5536783 0.854 ACTB
actin, beta
chr20_+_61838479 0.854 LIME1
Lck interacting transmembrane adaptor 1
chr1_-_226530350 0.851


chr8_+_22479115 0.846 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr10_+_134823925 0.845 NM_152643
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr8_-_133561738 0.844 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr7_-_5536704 0.842 NM_001101
ACTB
actin, beta
chr6_+_39868126 0.835 DAAM2
dishevelled associated activator of morphogenesis 2
chrX_+_152413646 0.823 BGN
biglycan
chr8_+_145231386 0.816 MAF1
MAF1 homolog (S. cerevisiae)
chr14_+_101097440 0.816 NM_001362
DIO3
deiodinase, iodothyronine, type III
chrX_+_152413540 0.816 NM_001711
BGN
biglycan
chr20_+_61838389 0.813 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr19_-_1814546 0.809 NM_031918
KLF16
Kruppel-like factor 16
chr1_+_226261374 0.806 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr3_+_14835472 0.804 NM_152536
FGD5
FYVE, RhoGEF and PH domain containing 5
chr18_-_5533967 0.803 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chrX_+_49013424 0.802 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr11_+_65792680 0.800 RAB1B
RAB1B, member RAS oncogene family
chr6_-_36915195 0.799 NM_020939
CPNE5
copine V
chr12_-_119038940 0.795 RAB35
RAB35, member RAS oncogene family
chr19_-_60802663 0.790 NM_032836
FIZ1
FLT3-interacting zinc finger 1
chr7_+_149733309 0.786


chr21_-_45786709 0.785 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr22_-_49062461 0.783 PLXNB2
plexin B2
chr12_-_119038836 0.779 RAB35
RAB35, member RAS oncogene family
chr16_-_87297525 0.775 NM_001171816
RNF166
ring finger protein 166
chr8_+_145231292 0.772 NM_032272
MAF1
MAF1 homolog (S. cerevisiae)
chr22_-_42589543 0.772 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chrX_+_153339814 0.771 NM_017514
PLXNA3
plexin A3
chr20_+_41978195 0.769 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr17_+_73738985 0.766 NM_001145529
TMEM235
transmembrane protein 235
chr7_+_75928907 0.757 NM_001102594
NM_001102595
NM_020892
DTX2


deltex homolog 2 (Drosophila)


chr9_+_130589330 0.744 NM_018201
TBC1D13
TBC1 domain family, member 13
chr17_-_18848713 0.743 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr3_+_52504410 0.736 STAB1
stabilin 1
chr8_+_121892719 0.734


chr19_-_61874934 0.731 ZNF835
zinc finger protein 835
chr19_-_1814425 0.730 KLF16
Kruppel-like factor 16
chr19_-_13978096 0.730 NM_002918
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr20_+_43896178 0.727 SNX21
sorting nexin family member 21
chr12_+_6907646 0.723 NM_001940
ATN1
atrophin 1
chr22_+_36928972 0.723 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr19_+_59333232 0.722 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr19_-_16514232 0.722 CHERP
calcium homeostasis endoplasmic reticulum protein
chr20_-_42872295 0.716 NM_182970
RIMS4
regulating synaptic membrane exocytosis 4
chrX_-_152592958 0.715 NM_001039582
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr8_-_133561933 0.708 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr10_-_121286034 0.708 NM_002925
RGS10
regulator of G-protein signaling 10
chr3_+_138965844 0.705 SOX14
SRY (sex determining region Y)-box 14
chr19_-_51081147 0.705 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr11_+_1925075 0.702 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr16_+_66236559 0.696 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr19_+_40716153 0.695 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_-_2333800 0.693 PEX10
peroxisomal biogenesis factor 10
chr3_-_58538110 0.691 FAM107A
family with sequence similarity 107, member A
chr7_-_139987044 0.691 DENND2A
DENN/MADD domain containing 2A
chr14_+_92049396 0.691 NM_024832
RIN3
Ras and Rab interactor 3
chr12_+_111829121 0.688 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr4_-_154929657 0.688 NM_003013
SFRP2
secreted frizzled-related protein 2
chr17_+_7252225 0.687 NM_020795
NLGN2
neuroligin 2
chr19_+_13111072 0.686 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr7_+_53070842 0.676 NM_182595
POM121L12
POM121 membrane glycoprotein-like 12
chr7_-_19151509 0.675 NM_152898
FERD3L
Fer3-like (Drosophila)
chr16_-_30453646 0.671 NM_023931
ZNF747
zinc finger protein 747
chr9_+_130589382 0.667 TBC1D13
TBC1 domain family, member 13
chr11_-_61415429 0.662 NM_021727
FADS3
fatty acid desaturase 3
chr19_+_49866563 0.661 NM_001127893
NM_020219
CEACAM19

carcinoembryonic antigen-related cell adhesion molecule 19

chr19_-_15172773 0.659 NM_000435
NOTCH3
notch 3
chr17_-_45582872 0.659 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr1_+_1437358 0.659 NM_001170535
NM_018188
ATAD3A

ATPase family, AAA domain containing 3A

chr1_-_16272523 0.658 NM_182623
FAM131C
family with sequence similarity 131, member C
chr22_+_35639564 0.654 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr16_-_87300233 0.651 NM_001171815
RNF166
ring finger protein 166
chr9_+_95378492 0.650 NM_005392
PHF2
PHD finger protein 2
chr1_-_9052253 0.649 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr12_+_109956210 0.647 NM_015267
CUX2
cut-like homeobox 2
chr15_+_38973893 0.646 NM_020857
VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr19_-_16514202 0.643 CHERP
calcium homeostasis endoplasmic reticulum protein
chr9_-_16860719 0.643 NM_017637
BNC2
basonuclin 2
chr1_+_99502655 0.642 LPPR4
lipid phosphate phosphatase-related protein type 4
chr19_-_16514256 0.641 NM_006387
CHERP
calcium homeostasis endoplasmic reticulum protein
chr3_-_16530132 0.639 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr8_+_120497732 0.639 NM_002514
NOV
nephroblastoma overexpressed gene
chr3_+_52504391 0.634 NM_015136
STAB1
stabilin 1
chr10_+_99069007 0.633 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr6_+_33352886 0.632 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr7_-_1510533 0.628 NM_001080453
INTS1
integrator complex subunit 1
chr8_-_70908130 0.627 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr19_-_16514247 0.627 CHERP
calcium homeostasis endoplasmic reticulum protein
chr16_-_1783653 0.626 NM_001146006
NM_004970
IGFALS

insulin-like growth factor binding protein, acid labile subunit

chr19_-_52426055 0.626 NM_014417
BBC3
BCL2 binding component 3
chr1_-_27825178 0.625 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_44593526 0.624 ERI3
ERI1 exoribonuclease family member 3
chr19_-_5573794 0.621 NM_014649
SAFB2
scaffold attachment factor B2
chr5_+_175241449 0.620 CPLX2
complexin 2
chr7_-_150129295 0.616 NM_014020
TMEM176B
transmembrane protein 176B
chr19_+_53589943 0.616 NM_000836
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr6_-_109868400 0.615 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr12_-_131415854 0.613 NM_001122636
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr1_-_2333863 0.612 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr16_-_87300308 0.610 NM_178841
RNF166
ring finger protein 166
chr19_-_44214972 0.608 NM_178820
FBXO27
F-box protein 27
chr8_-_65873658 0.607 NM_004820
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr3_+_13496714 0.603 NM_024827
NM_001136041
HDAC11

histone deacetylase 11

chr22_+_35586950 0.601 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr17_+_7549138 0.600 NM_001406
EFNB3
ephrin-B3
chr16_+_53915971 0.599 NM_024335
IRX6
iroquois homeobox 6
chrX_+_70899864 0.597 NM_001145140
NM_001145139
CXorf49
CXorf49B
chromosome X open reading frame 49
chromosome X open reading frame 49B
chr19_+_14108974 0.597


chrX_+_152608159 0.595 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr8_+_145137354 0.592 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr10_-_120345148 0.591 NM_004248
PRLHR
prolactin releasing hormone receptor
chr20_-_43972982 0.590 PLTP
phospholipid transfer protein
chr1_+_1437400 0.590 ATAD3A
ATAD3B
ATPase family, AAA domain containing 3A
ATPase family, AAA domain containing 3B
chr19_+_43502360 0.589 KCNK6
potassium channel, subfamily K, member 6
chr19_-_1518875 0.585 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr20_+_29526751 0.585 NM_014012
REM1
RAS (RAD and GEM)-like GTP-binding 1
chr19_-_5291700 0.584 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr3_-_129023850 0.581 NM_007283
MGLL
monoglyceride lipase
chr22_+_48740432 0.580 PIM3
pim-3 oncogene
chr12_+_131577229 0.577 NM_001142641
FBRSL1
fibrosin-like 1
chr8_+_144711619 0.574 NM_024736
GSDMD
gasdermin D
chr16_-_30453499 0.572 ZNF747
zinc finger protein 747
chr14_-_67051773 0.570 NM_182526
TMEM229B
transmembrane protein 229B
chr19_+_52940604 0.569 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr8_+_142207866 0.569 NM_014957
DENND3
DENN/MADD domain containing 3
chr10_+_3099708 0.568 NM_002627
PFKP
phosphofructokinase, platelet
chr8_-_22022757 0.555 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr3_-_16529996 0.551 RFTN1
raftlin, lipid raft linker 1
chr5_+_131774478 0.551 NM_001013717
C5orf56
chromosome 5 open reading frame 56
chrX_+_136475979 0.550 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr5_+_68823874 0.550 NM_002538
OCLN
occludin
chr7_-_1144347 0.546 NM_001134395
NM_001134396
NM_032350
C7orf50


chromosome 7 open reading frame 50



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.58 6.71e-07 GO:0007399 nervous system development
1.31 1.31e-03 GO:0048731 system development
1.39 1.59e-03 GO:0048583 regulation of response to stimulus
1.25 4.08e-03 GO:0032502 developmental process
1.14 4.26e-03 GO:0065007 biological regulation
1.44 4.88e-03 GO:0009966 regulation of signal transduction
1.43 5.14e-03 GO:0009653 anatomical structure morphogenesis
2.50 6.95e-03 GO:0045926 negative regulation of growth
1.25 1.01e-02 GO:0007275 multicellular organismal development
1.26 1.52e-02 GO:0048856 anatomical structure development
1.31 1.61e-02 GO:0048519 negative regulation of biological process
1.22 1.86e-02 GO:0051716 cellular response to stimulus
1.83 1.91e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.32 2.79e-02 GO:0048523 negative regulation of cellular process
1.51 2.84e-02 GO:0022008 neurogenesis
1.37 3.15e-02 GO:0023051 regulation of signaling
1.14 3.87e-02 GO:0050789 regulation of biological process
1.22 4.37e-02 GO:0023052 signaling
1.24 4.61e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 6.62e-04 GO:0005737 cytoplasm
1.31 2.77e-03 GO:0044459 plasma membrane part
1.20 1.23e-02 GO:0005886 plasma membrane
1.19 1.69e-02 GO:0071944 cell periphery
1.72 2.73e-02 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 1.87e-03 GO:0005515 protein binding