Motif ID: EBF1.p2

Z-value: 0.725


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EBF1chr5_-_1584590060.562.3e-02Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_56884560 2.006 TBX4
T-box 4
chr17_+_71095733 1.720 MYO15B
myosin XVB pseudogene
chr17_-_8034217 1.255 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr17_-_8034071 1.198 C17orf59
chromosome 17 open reading frame 59
chr6_-_43586401 1.197 NM_001012974
C6orf154
chromosome 6 open reading frame 154
chr1_-_1041321 1.150 C1orf159
chromosome 1 open reading frame 159
chr4_+_41057600 1.017


chr22_+_35586950 0.981 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr12_-_123617962 0.969 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr22_-_35875890 0.955 NM_000878
IL2RB
interleukin 2 receptor, beta
chr19_+_55627971 0.949 NM_004533
MYBPC2
myosin binding protein C, fast type
chr20_-_60228665 0.913 NM_007232
HRH3
histamine receptor H3
chr19_-_2259155 0.873 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr16_+_85101734 0.841 FOXF1
forkhead box F1
chr19_-_56018815 0.841 NM_002257
KLK1
kallikrein 1
chr10_-_21825879 0.836 C10orf114
chromosome 10 open reading frame 114
chr9_+_138341752 0.830 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr19_+_53559468 0.827 NM_012451
SYNGR4
synaptogyrin 4
chr7_+_288051 0.821 NM_020223
FAM20C
family with sequence similarity 20, member C
chr8_+_8597075 0.817 NM_194284
CLDN23
claudin 23
chr16_+_85101605 0.807 NM_001451
FOXF1
forkhead box F1
chr14_+_23937766 0.799 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr1_-_149385556 0.799 NM_001178061
NM_001178062
NM_030913
SEMA6C


sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C


chr4_+_2764609 0.795 SH3BP2
SH3-domain binding protein 2
chr17_+_75808685 0.759 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr1_-_16217871 0.754 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr17_+_44642587 0.750 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr15_-_73792234 0.743 NM_001897
CSPG4
chondroitin sulfate proteoglycan 4
chr2_+_219432789 0.738 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr9_-_135334003 0.738 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr1_-_20931719 0.727 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr8_-_22145795 0.726 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr6_+_169844128 0.713 C6orf120
chromosome 6 open reading frame 120
chr8_-_144726064 0.703 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr1_-_201420927 0.701 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr17_-_34635446 0.697 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr11_+_61491793 0.693 LOC399900
hypothetical LOC399900
chr5_-_904100 0.691 NM_024786
ZDHHC11
zinc finger, DHHC-type containing 11
chr1_+_891739 0.688 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr19_+_60283571 0.676 NM_017729
EPS8L1
EPS8-like 1
chr16_+_3036682 0.675 NM_022468
MMP25
matrix metallopeptidase 25
chr19_-_2187648 0.671 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr6_+_1335067 0.669 NM_001452
FOXF2
forkhead box F2
chr8_-_11361594 0.669 NM_053279
FAM167A
family with sequence similarity 167, member A
chr10_-_135021502 0.668 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr11_+_46256161 0.664 CREB3L1
cAMP responsive element binding protein 3-like 1
chr2_+_222871109 0.661 NM_153038
CCDC140
coiled-coil domain containing 140
chr8_-_145552919 0.660 NM_012162
NM_024555
FBXL6

F-box and leucine-rich repeat protein 6

chr19_+_60688349 0.655 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr19_-_60369731 0.654 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr8_+_142207866 0.647 NM_014957
DENND3
DENN/MADD domain containing 3
chr1_-_33420213 0.635 NM_018207
TRIM62
tripartite motif containing 62
chr1_-_27871306 0.634 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr19_+_54669629 0.630 FLT3LG
fms-related tyrosine kinase 3 ligand
chr4_+_46728051 0.629 NM_000812
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr16_+_66236559 0.625 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_-_24973940 0.623 CORO6
coronin 6
chrX_+_48906124 0.623 NM_001099681
NM_001099682
NM_024859
MAGIX


MAGI family member, X-linked


chr6_-_2580296 0.622 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr6_-_132764257 0.622 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr4_-_85638410 0.616 NM_006168
NKX6-1
NK6 homeobox 1
chr8_-_22022757 0.606 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr16_+_658081 0.606 NM_138769
RHOT2
ras homolog gene family, member T2
chr19_-_1836485 0.605 NM_001130111
NM_031213
FAM108A1

family with sequence similarity 108, member A1

chr9_-_138762725 0.604 NM_198946
LCN6
lipocalin 6
chr3_+_67787810 0.602


chr6_-_32742265 0.602 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr11_+_124240491 0.600 NM_022370
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr7_-_142293382 0.596 NM_018646
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr11_+_69602055 0.595 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr12_-_46439127 0.593 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_-_203592538 0.590 NM_018203
KLHDC8A
kelch domain containing 8A
chr19_-_18912112 0.590 NM_001145722
NM_001145721
HOMER3

homer homolog 3 (Drosophila)

chr2_-_27215781 0.583 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr10_+_73393998 0.581 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr16_+_22733307 0.580 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr3_-_151904408 0.580 NM_152394
FAM194A
family with sequence similarity 194, member A
chr17_-_76064842 0.576 NM_002522
NPTX1
neuronal pentraxin I
chr19_+_11510578 0.575 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr1_+_110000220 0.573 NM_000850
NM_147148
GSTM4

glutathione S-transferase mu 4

chr17_-_43862480 0.565 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr19_+_17723285 0.565 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr7_-_98305419 0.565 TMEM130
transmembrane protein 130
chr19_-_14467939 0.557 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr15_+_43209422 0.555 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr19_+_60851207 0.554 CCDC106
coiled-coil domain containing 106
chr4_-_7487514 0.550 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr20_+_62181878 0.549 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr17_-_35975227 0.546 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr22_-_16127520 0.546 CECR3
cat eye syndrome chromosome region, candidate 3
chr19_+_54669283 0.545 NM_001459
FLT3LG
fms-related tyrosine kinase 3 ligand
chr19_+_2187815 0.544 NM_007165
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr1_+_1540657 0.543 NM_001170686
NM_001170687
NM_001170688
NM_080875
MIB2



mindbomb homolog 2 (Drosophila)



chr11_-_117252541 0.540 FXYD6
FXYD domain containing ion transport regulator 6
chr2_+_238712101 0.539 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr1_+_1541067 0.538 NM_001170689
MIB2
mindbomb homolog 2 (Drosophila)
chr17_-_1874927 0.537 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr10_+_99322187 0.536 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr6_-_167195987 0.536 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr22_+_36008369 0.535 NM_013385
CYTH4
cytohesin 4
chr8_+_145674247 0.532 PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr1_+_43508251 0.530 NM_144626
TMEM125
transmembrane protein 125
chr1_-_155336223 0.530 NM_001004341
ETV3L
ets variant 3-like
chr19_-_61874934 0.530 ZNF835
zinc finger protein 835
chr16_-_29373785 0.528 NM_001031827
NM_001039182
BOLA2
BOLA2B
bolA homolog 2 (E. coli)
bolA homolog 2B (E. coli)
chr19_-_14467890 0.525 GIPC1
GIPC PDZ domain containing family, member 1
chr14_+_104523660 0.521 NM_174891
C14orf79
chromosome 14 open reading frame 79
chr17_-_28644118 0.521 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr1_-_201411533 0.520 NM_004997
MYBPH
myosin binding protein H
chr16_-_56562512 0.520 NM_001135639
NM_001297
CNGB1

cyclic nucleotide gated channel beta 1

chr11_+_1200894 0.519 MUC5B
mucin 5B, oligomeric mucus/gel-forming
chr15_-_76890626 0.518 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr6_-_167195647 0.518 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr5_-_177355848 0.518 NM_006261
PROP1
PROP paired-like homeobox 1
chr19_+_40824486 0.516 NM_014209
ETV2
ets variant 2
chr19_+_60679510 0.514 NM_033113
ZNF628
zinc finger protein 628
chr3_-_144090427 0.513 NM_013363
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr2_-_110231431 0.513 NM_005434
MALL
mal, T-cell differentiation protein-like
chr22_-_41446740 0.512 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chr22_-_49413326 0.510 NM_000487
NM_001085425
NM_001085426
NM_001085427
NM_001085428
ARSA




arylsulfatase A




chr8_+_134272463 0.508 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr10_-_88720908 0.507 LOC100133190
hypothetical LOC100133190
chr14_-_104602784 0.507 NM_013345
GPR132
G protein-coupled receptor 132
chr19_-_4016467 0.507 ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_149200937 0.507 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr1_-_1300416 0.506 NM_001127230
NM_001127229
AURKAIP1

aurora kinase A interacting protein 1

chr3_+_133861425 0.505 UBA5
ubiquitin-like modifier activating enzyme 5
chr22_-_19122107 0.504 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr11_+_60391590 0.501 NM_207341
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr15_-_76210611 0.501 NM_006383
CIB2
calcium and integrin binding family member 2
chr1_+_110000247 0.500 GSTM4
glutathione S-transferase mu 4
chr9_-_139010805 0.498 NM_004669
CLIC3
chloride intracellular channel 3
chr10_-_134605978 0.497 NM_173572
C10orf93
chromosome 10 open reading frame 93
chr9_-_132804243 0.497 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr5_+_10617431 0.495 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr9_+_126579203 0.493 NM_182487
OLFML2A
olfactomedin-like 2A
chr9_-_139214962 0.493 NM_001128228
TPRN
taperin
chr10_-_725522 0.491 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr8_-_22145462 0.490 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr6_-_43585958 0.489 C6orf154
chromosome 6 open reading frame 154
chr17_+_74531820 0.483 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr1_-_27871245 0.482 IFI6
interferon, alpha-inducible protein 6
chr19_+_3136860 0.481 NM_020170
NCLN
nicalin
chr17_+_77219703 0.479 NM_031945
TSPAN10
tetraspanin 10
chr1_-_153107084 0.477


chr1_-_32600430 0.476 NM_001167676
LOC100128071
hypothetical LOC100128071
chr15_-_69194854 0.475 NM_001102658
CT62
cancer/testis antigen 62
chrX_+_117841761 0.475 NM_173798
ZCCHC12
zinc finger, CCHC domain containing 12
chr2_+_12775336 0.474 TRIB2
tribbles homolog 2 (Drosophila)
chr7_-_138818948 0.474 NM_198508
KLRG2
killer cell lectin-like receptor subfamily G, member 2
chr5_+_148186348 0.473 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr4_-_6253152 0.468 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr10_+_46503539 0.467 NM_005972
PPYR1
pancreatic polypeptide receptor 1
chr10_+_71908535 0.465 NM_014431
KIAA1274
KIAA1274
chr4_+_42094612 0.464 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr5_+_193372 0.463 NM_052909
PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr9_-_25668230 0.463 TUSC1
tumor suppressor candidate 1
chr2_+_233029076 0.463 NM_001631
ALPI
alkaline phosphatase, intestinal
chr8_+_145553016 0.462 NM_024531
GPR172A
G protein-coupled receptor 172A
chr12_+_5023345 0.461 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr17_+_24919787 0.460 TP53I13
tumor protein p53 inducible protein 13
chr1_-_225989703 0.460 NM_001161465
NM_023007
JMJD4

jumonji domain containing 4

chr6_-_34632061 0.460 NM_012391
SPDEF
SAM pointed domain containing ets transcription factor
chr15_-_66511488 0.458 NM_001004439
ITGA11
integrin, alpha 11
chr11_-_72182291 0.457 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr5_+_148941228 0.457 NM_001001669
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr17_+_24919864 0.457 NM_138349
TP53I13
tumor protein p53 inducible protein 13
chr19_+_18655487 0.453 CRTC1
CREB regulated transcription coactivator 1
chr15_-_73792150 0.452 CSPG4
chondroitin sulfate proteoglycan 4
chr3_+_127743868 0.451 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_5631910 0.450 NM_205767
C19orf70
chromosome 19 open reading frame 70
chr2_-_70042900 0.447 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chr3_-_45813116 0.446 SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_224803123 0.445 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr9_-_138560058 0.445 NM_017617
NOTCH1
notch 1
chr4_+_2783764 0.445 SH3BP2
SH3-domain binding protein 2
chr19_-_1352474 0.444 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr14_+_104117100 0.444 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr5_+_176786279 0.443 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr19_+_3136927 0.439 NCLN
nicalin
chr17_+_25910709 0.439 NM_015594
TBC1D29
TBC1 domain family, member 29
chr2_+_27154938 0.438 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr19_+_48549664 0.437 NM_020406
CD177
CD177 molecule
chr6_-_170441493 0.437 NM_005618
DLL1
delta-like 1 (Drosophila)
chr19_+_18655391 0.436 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr19_+_46507872 0.435 NM_052848
CCDC97
coiled-coil domain containing 97
chr5_-_1498510 0.434 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr1_+_32489426 0.433 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_8306976 0.432 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr9_+_4480193 0.431 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr16_-_31390926 0.429


chr7_+_49783774 0.429 NM_198570
VWC2
von Willebrand factor C domain containing 2
chr4_-_41579325 0.429


chr17_-_77244034 0.428 C17orf90
chromosome 17 open reading frame 90
chr5_+_57914658 0.428 NM_138453
RAB3C
RAB3C, member RAS oncogene family
chr9_-_135140425 0.427 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr15_-_73036179 0.427 RPP25
ribonuclease P/MRP 25kDa subunit
chr10_-_91451102 0.426 NBAS
neuroblastoma amplified sequence
chr19_-_1993022 0.426 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_+_232107170 0.425 NM_173508
SLC35F3
solute carrier family 35, member F3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 1.04e-03 GO:0023052 signaling
2.28 6.64e-03 GO:0035023 regulation of Rho protein signal transduction
1.30 7.08e-03 GO:0023051 regulation of signaling
1.28 8.89e-03 GO:0048583 regulation of response to stimulus
1.32 1.19e-02 GO:0009966 regulation of signal transduction
1.79 2.04e-02 GO:0046578 regulation of Ras protein signal transduction
1.18 4.90e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 2.85e-04 GO:0044459 plasma membrane part
1.11 3.84e-04 GO:0016020 membrane
1.17 5.50e-04 GO:0005886 plasma membrane
1.17 9.37e-04 GO:0071944 cell periphery
1.11 1.49e-02 GO:0044425 membrane part
2.14 2.06e-02 GO:0005925 focal adhesion

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.47 2.40e-04 GO:0003823 antigen binding
2.50 6.12e-03 GO:0005089 Rho guanyl-nucleotide exchange factor activity
1.93 1.35e-02 GO:0005085 guanyl-nucleotide exchange factor activity
2.25 1.78e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity