Motif ID: ATF6.p2

Z-value: 1.354


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002693,
chr1_+_160002733		0.126.6e-01Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_44043361 1.776 NM_004502
 HOXB7
homeobox B7
chrX_-_100801472 1.631 NM_014782
NM_177949
 ARMCX2

armadillo repeat containing, X-linked 2

chr7_+_128257698 1.596 NM_001127487
NM_001458
 FLNC

filamin C, gamma

chr1_+_26368969 1.342 NM_015871
 ZNF593
zinc finger protein 593
chr2_+_28469172 1.144 FOSL2
FOS-like antigen 2
chr14_+_100362204 1.067 MEG3
maternally expressed 3 (non-protein coding)
chr17_-_44042924 1.061 HOXB7
homeobox B7
chr7_+_27191534 0.897 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr15_-_80125403 0.883 NM_032246
 MEX3B
mex-3 homolog B (C. elegans)
chr4_-_186693574 0.865 NM_001114107
NM_014476
 PDLIM3

PDZ and LIM domain 3

chr12_+_110935612 0.840


chr2_+_28469275 0.814 NM_005253
 FOSL2
FOS-like antigen 2
chr19_+_54723044 0.784 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr15_-_80125514 0.783 MEX3B
mex-3 homolog B (C. elegans)
chr9_-_78710698 0.777 NM_015225
 PRUNE2
prune homolog 2 (Drosophila)
chr7_-_27191287 0.777 NM_005523
 HOXA11
homeobox A11
chr7_+_93861808 0.754 NM_000089
 COL1A2
collagen, type I, alpha 2
chr17_-_44043278 0.727 HOXB7
homeobox B7
chr10_-_62373828 0.720 NM_014836
 RHOBTB1
Rho-related BTB domain containing 1
chr5_+_170221584 0.701 NM_022897
 RANBP17
RAN binding protein 17

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
8.23 2.72e-05 GO:0048199 vesicle targeting, to, from or within Golgi
6.23 3.51e-03 GO:0006901 vesicle coating
5.99 5.49e-03 GO:0006900 membrane budding
5.49 4.73e-03 GO:0006903 vesicle targeting
3.06 3.89e-04 GO:0048193 Golgi vesicle transport
2.09 2.47e-05 GO:0034613 cellular protein localization
2.08 3.18e-05 GO:0070727 cellular macromolecule localization
2.01 5.95e-03 GO:0006886 intracellular protein transport
1.89 3.94e-03 GO:0010942 positive regulation of cell death
1.88 1.60e-08 GO:0008104 protein localization
1.87 8.16e-03 GO:0043065 positive regulation of apoptosis
1.86 7.28e-06 GO:0015031 protein transport
1.86 9.98e-03 GO:0043068 positive regulation of programmed cell death
1.84 1.01e-04 GO:0016192 vesicle-mediated transport
1.84 3.87e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.82 1.83e-05 GO:0045184 establishment of protein localization
1.80 1.91e-04 GO:0046907 intracellular transport
1.76 1.66e-04 GO:0006351 transcription, DNA-dependent
1.75 1.04e-07 GO:0033036 macromolecule localization
1.71 1.88e-06 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
7.48 2.32e-02 GO:0030126 COPI vesicle coat
4.60 2.26e-03 GO:0030120 vesicle coat
3.85 4.42e-04 GO:0030117 membrane coat
3.85 4.42e-04 GO:0048475 coated membrane
3.60 1.75e-02 GO:0005798 Golgi-associated vesicle
1.90 8.41e-04 GO:0000139 Golgi membrane
1.83 4.65e-04 GO:0044431 Golgi apparatus part
1.57 4.16e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.56 3.16e-03 GO:0005794 Golgi apparatus
1.56 3.35e-02 GO:0031410 cytoplasmic vesicle
1.56 4.36e-02 GO:0031988 membrane-bounded vesicle
1.55 3.34e-02 GO:0031982 vesicle
1.49 1.61e-02 GO:0005783 endoplasmic reticulum
1.48 3.73e-04 GO:0012505 endomembrane system
1.37 2.74e-03 GO:0031090 organelle membrane
1.23 1.14e-04 GO:0005634 nucleus
1.22 1.40e-04 GO:0044422 organelle part
1.22 1.75e-04 GO:0044446 intracellular organelle part
1.21 9.33e-10 GO:0043227 membrane-bounded organelle
1.21 1.11e-09 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.73 1.39e-03 GO:0043565 sequence-specific DNA binding
1.68 5.95e-05 GO:0001071 nucleic acid binding transcription factor activity
1.68 5.95e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.62 4.96e-04 GO:0030528 transcription regulator activity
1.22 7.70e-07 GO:0005515 protein binding
1.10 1.50e-03 GO:0005488 binding