Motif ID: PBX1.p2

Z-value: 0.894


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_1627953280.485.8e-02Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_189752575 0.969 NM_000393
 COL5A2
collagen, type V, alpha 2
chr17_+_70495318 0.966 NM_014603
 CDR2L
cerebellar degeneration-related protein 2-like
chr6_-_166960690 0.805 NM_021135
 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr22_-_28972683 0.786 NM_002309
 LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr2_+_20510312 0.758 NM_004040
 RHOB
ras homolog gene family, member B
chr10_+_124310170 0.634 NM_004406
NM_007329
NM_017579
 DMBT1


deleted in malignant brain tumors 1


chr3_+_112934016 0.630 NM_001134437
 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr13_-_109236897 0.556 NM_003749
 IRS2
insulin receptor substrate 2
chr12_+_77782719 0.525 SYT1
synaptotagmin I
chr5_-_171814026 0.523 NM_001017995
 SH3PXD2B
SH3 and PX domains 2B
chr6_-_166960649 0.516 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr5_-_149515613 0.495 NM_002609
 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr4_+_86968069 0.459 ARHGAP24
Rho GTPase activating protein 24
chr5_+_54434230 0.444 NM_006144
 GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr5_+_15553288 0.432 NM_012304
 FBXL7
F-box and leucine-rich repeat protein 7
chrX_-_10605726 0.423 NM_001098624
 MID1
midline 1 (Opitz/BBB syndrome)
chr14_+_54104383 0.421 NM_001161576
NM_015589
 SAMD4A

sterile alpha motif domain containing 4A

chrX_-_92815222 0.419 NM_004538
 NAP1L3
nucleosome assembly protein 1-like 3
chr9_+_112470871 0.408 NM_001166280
NM_001166281
NM_005592
 MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_+_161040343 0.406 NM_001197109
 SCHIP1
schwannomin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
5.34 6.06e-05 GO:0006334 nucleosome assembly
5.22 1.24e-05 GO:0065004 protein-DNA complex assembly
5.06 1.30e-04 GO:0031497 chromatin assembly
4.94 3.01e-05 GO:0071824 protein-DNA complex subunit organization
4.82 2.66e-04 GO:0034728 nucleosome organization
4.12 1.11e-03 GO:0006323 DNA packaging
3.85 2.90e-03 GO:0006333 chromatin assembly or disassembly
3.54 9.26e-03 GO:0071103 DNA conformation change
2.82 2.96e-04 GO:0034622 cellular macromolecular complex assembly
2.40 2.35e-03 GO:0034621 cellular macromolecular complex subunit organization
2.14 9.97e-04 GO:0071844 cellular component assembly at cellular level
1.99 2.95e-02 GO:0065003 macromolecular complex assembly
1.88 4.28e-02 GO:0043933 macromolecular complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
6.50 1.63e-05 GO:0000786 nucleosome
5.12 1.81e-05 GO:0032993 protein-DNA complex
2.53 4.84e-02 GO:0000785 chromatin
1.14 2.98e-02 GO:0043229 intracellular organelle
1.13 3.54e-02 GO:0043226 organelle

Nothing significant found in function category.