Motif ID: NR3C1.p2

Z-value: 0.713


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_142763393-0.495.3e-02Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_20098929 1.030 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
 RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_-_122126422 0.910 NM_139175
 RNF133
ring finger protein 133
chr6_-_32299757 0.696 NM_004557
 NOTCH4
notch 4
chr22_+_39404940 0.629 NM_005297
 MCHR1
melanin-concentrating hormone receptor 1
chr20_-_44612619 0.625 NM_080721
 C20orf123
chromosome 20 open reading frame 123
chr9_-_70780574 0.621


chr3_+_2117246 0.607 NM_175607
 CNTN4
contactin 4
chr11_+_110631916 0.578 NM_198498
 C11orf53
chromosome 11 open reading frame 53
chr1_+_103961476 0.575 NM_000699
 AMY2A
amylase, alpha 2A (pancreatic)
chr8_-_31010772 0.575 NM_001015508
 PURG
purine-rich element binding protein G
chr6_+_134251940 0.535 NM_198392
NM_003206
 TCF21

transcription factor 21

chr6_+_134251957 0.532 TCF21
transcription factor 21
chr11_+_4799126 0.514 NM_001004753
 OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr22_+_21042091 0.512 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr20_+_42776888 0.504 WISP2
WNT1 inducible signaling pathway protein 2
chr4_+_71713324 0.503 NM_031889
 ENAM
enamelin
chr11_+_73036241 0.501 NM_001130034
NM_001130035
 PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr17_+_42641426 0.489 NM_001002841
 MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr4_+_91035025 0.480 NM_007351
 MMRN1
multimerin 1
chr2_+_107969410 0.470 NM_021815
 SLC5A7
solute carrier family 5 (choline transporter), member 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.37 1.90e-10 GO:0007608 sensory perception of smell
3.01 1.15e-08 GO:0007606 sensory perception of chemical stimulus
2.35 1.53e-07 GO:0007600 sensory perception
1.88 1.27e-05 GO:0050877 neurological system process
1.72 8.98e-05 GO:0003008 system process
1.66 3.51e-02 GO:0002376 immune system process
1.31 6.89e-05 GO:0050896 response to stimulus
1.30 2.45e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.89 1.76e-03 GO:0005615 extracellular space
1.69 1.17e-02 GO:0044421 extracellular region part
1.65 6.60e-06 GO:0005576 extracellular region
1.63 4.20e-14 GO:0005886 plasma membrane
1.61 1.16e-13 GO:0071944 cell periphery
1.42 1.43e-09 GO:0031224 intrinsic to membrane
1.40 2.63e-08 GO:0016021 integral to membrane
1.35 1.67e-08 GO:0044425 membrane part
1.29 4.70e-08 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
10.55 2.41e-02 GO:0004522 pancreatic ribonuclease activity
7.83 2.93e-02 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
5.48 3.06e-02 GO:0003823 antigen binding
3.46 3.51e-11 GO:0004984 olfactory receptor activity
2.58 1.73e-11 GO:0004930 G-protein coupled receptor activity
2.05 1.90e-08 GO:0004888 transmembrane receptor activity
2.02 1.96e-11 GO:0004872 receptor activity
1.81 3.10e-09 GO:0004871 signal transducer activity
1.81 3.10e-09 GO:0060089 molecular transducer activity