Motif ID: ZBTB16.p2

Z-value: 1.589


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB16chr11_+_1134356400.292.8e-01Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_14554895 2.554 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr1_+_196874759 2.459 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_196874839 1.943 PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_-_38460983 1.899 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr9_-_124949033 1.874 STRBP
spermatid perinuclear RNA binding protein
chr4_+_74825138 1.762 NM_000584
IL8
interleukin 8
chr9_+_263025 1.723 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr12_-_51887266 1.596 NM_000889
ITGB7
integrin, beta 7
chr8_-_81155564 1.544 NM_001025252
TPD52
tumor protein D52
chr6_+_28032997 1.529 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr13_-_45654292 1.505 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_23955223 1.376 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr9_+_104797413 1.329 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr4_-_69852090 1.327 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr18_+_606671 1.325 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr11_+_89403921 1.315 NM_001195234
TRIM49
TRIM49L2
tripartite motif containing 49
tripartite motif containing 49-like 2
chr4_+_74566325 1.307 NM_001133
AFM
afamin
chr1_+_196874867 1.287 PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_+_35959638 1.283 NM_001136536
DTHD1
death domain containing 1
chr1_+_173111306 1.283 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_165643064 1.267 NM_144980
C6orf118
chromosome 6 open reading frame 118
chr7_+_7573074 1.242 NM_019005
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chrX_+_79562601 1.213 NM_152630
FAM46D
family with sequence similarity 46, member D
chr9_-_94284455 1.204 ASPN
asporin
chr7_+_7573159 1.197 MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chrX_-_153903963 1.197 NM_000132
F8
coagulation factor VIII, procoagulant component
chr11_-_6746763 1.190 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr9_-_94284571 1.167 NM_001193335
NM_017680
ASPN

asporin

chr19_-_20636152 1.162 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr16_+_20682812 1.146 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr6_-_74284522 1.134 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr21_-_14840506 1.113 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr9_-_70780574 1.110


chr7_+_106293112 1.085 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr10_-_98315090 1.080 TM9SF3
transmembrane 9 superfamily member 3
chr2_-_136590210 1.059 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr2_-_17563186 1.042 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr3_+_99733432 1.032 NM_005290
GPR15
G protein-coupled receptor 15
chr12_-_10953427 1.024 NM_023920
TAS2R13
taste receptor, type 2, member 13
chrX_+_134803450 1.008 NM_018666
SAGE1
sarcoma antigen 1
chr2_-_95514205 1.007 NM_001164464
TRIM43
TRIM43B
tripartite motif containing 43
tripartite motif containing 43B
chr10_+_62208094 0.993 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr1_+_100099353 0.990 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr5_-_88235624 0.983 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr6_+_12825818 0.977 NM_030948
PHACTR1
phosphatase and actin regulator 1
chrX_-_153698930 0.976 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr2_-_135498716 0.975 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr22_-_15682555 0.968 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr7_-_33047042 0.964 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr21_-_14501114 0.957 NM_198996
LIPI
lipase, member I
chr19_-_58016696 0.944 NM_006969
ZNF28
zinc finger protein 28
chr10_-_64698831 0.943 NM_004241
JMJD1C
jumonji domain containing 1C
chr19_-_20399601 0.940 ZNF826P
zinc finger protein 826, pseudogene
chr10_+_15125900 0.935 NM_001039702
NM_018324
OLAH

oleoyl-ACP hydrolase

chr11_-_5756472 0.928 NM_001001922
OR52N5
olfactory receptor, family 52, subfamily N, member 5
chr10_+_70517823 0.927 NM_002727
SRGN
serglycin
chr3_-_186752952 0.919 NM_139248
LIPH
lipase, member H
chr10_+_90511142 0.916 NM_001102469
LIPN
lipase, family member N
chr6_-_33149244 0.901 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr1_-_13546097 0.894 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chr12_-_88573949 0.887 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr2_+_161701711 0.886 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chrX_-_23765377 0.875 RPL9
ribosomal protein L9
chr1_-_149004916 0.866 NM_004079
CTSS
cathepsin S
chr3_-_95230143 0.865 NM_001001850
STX19
syntaxin 19
chrX_-_100015783 0.864 NM_007052
NM_013955
NOX1

NADPH oxidase 1

chr18_-_68683913 0.858 NM_138999
NM_153181
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1

chr13_-_98757634 0.857 NM_004951
GPR183
G protein-coupled receptor 183
chr2_-_87102453 0.853 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_+_28406990 0.853 NM_001040432
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr10_+_70517863 0.828 SRGN
serglycin
chrX_+_35847771 0.825 NM_152632
CXorf22
chromosome X open reading frame 22
chr12_-_10453409 0.823 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chrX_+_12795111 0.814 NM_016562
TLR7
toll-like receptor 7
chr4_-_64957595 0.808 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_73397929 0.804 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr10_-_93992982 0.803 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr8_-_16094591 0.798 NM_002445
NM_138715
NM_138716
MSR1


macrophage scavenger receptor 1


chr6_-_33085329 0.797 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr1_-_115039614 0.788 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr3_+_46370228 0.787 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr12_+_63510481 0.785


chr5_+_85949518 0.775 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr2_-_178681311 0.775 NM_001077197
PDE11A
phosphodiesterase 11A
chr3_+_39346200 0.766 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr14_-_74669864 0.762 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr1_-_156923111 0.757 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_+_142175329 0.756 SLC25A36
solute carrier family 25, member 36
chr19_-_21438525 0.752


chr12_-_53975282 0.747 NM_001005493
OR6C6
olfactory receptor, family 6, subfamily C, member 6
chr1_-_20318578 0.746 NM_012400
PLA2G2D
phospholipase A2, group IID
chr2_+_204509698 0.745 NM_012092
ICOS
inducible T-cell co-stimulator
chr2_+_173940179 0.741 CDCA7
cell division cycle associated 7
chr19_-_45141473 0.734 LOC440525
PRR13
proline rich 13 pseudogene
proline rich 13
chr10_-_42183441 0.734 LOC283027
hypothetical protein LOC283027
chr1_-_111771877 0.730 NM_002557
OVGP1
oviductal glycoprotein 1, 120kDa
chr4_-_38710376 0.728 NM_024943
TMEM156
transmembrane protein 156
chr8_-_37847095 0.725 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr14_+_87541220 0.725 NM_003608
GPR65
G protein-coupled receptor 65
chr9_+_6710862 0.724 NM_001146696
KDM4C
lysine (K)-specific demethylase 4C
chr16_+_80370400 0.723 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr14_-_20098929 0.718 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr7_+_37689903 0.717


chr19_+_42409205 0.705 NM_152604
ZNF383
zinc finger protein 383
chr15_+_39839866 0.703 MGA
MAX gene associated
chr12_-_69434650 0.703 PTPRR
protein tyrosine phosphatase, receptor type, R
chr7_+_129634935 0.699 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr3_-_15357878 0.698 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr7_-_92615593 0.688 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr12_+_111375382 0.682 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr12_-_93991235 0.681 NM_001032287
NM_001127362
NM_003297
NR2C1


nuclear receptor subfamily 2, group C, member 1


chr9_-_14912419 0.678


chr18_+_27925859 0.677 RNF138
ring finger protein 138
chr12_+_53178834 0.670 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr1_-_204455269 0.665 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr2_+_172252194 0.664 NM_001378
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr6_+_116956868 0.663 NM_153036
FAM26D
family with sequence similarity 26, member D
chr7_+_99263571 0.663 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr6_+_10629550 0.661 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_9777126 0.661 NM_172004
CLECL1
C-type lectin-like 1
chr1_+_111571803 0.661 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr11_-_55757236 0.658 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr12_+_94200306 0.651 VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_108588186 0.648 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr5_-_88155360 0.648 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr13_+_77213295 0.647 NM_144595
SLAIN1
SLAIN motif family, member 1
chr21_+_42697058 0.643 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr12_-_55432348 0.640 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr15_-_91078307 0.639 FAM174B
family with sequence similarity 174, member B
chr8_-_108579270 0.637 NM_001146
ANGPT1
angiopoietin 1
chr6_+_27885692 0.632 NM_003536
HIST1H3H
histone cluster 1, H3h
chr3_-_184756101 0.631 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_+_76024466 0.626 NM_004582
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr1_+_154120170 0.626 SYT11
synaptotagmin XI
chr1_+_51340487 0.619 NM_001136508
C1orf185
chromosome 1 open reading frame 185
chr1_+_245779018 0.614 NM_145278
C1orf150
chromosome 1 open reading frame 150
chr6_+_71192862 0.614 NM_001162529
FAM135A
family with sequence similarity 135, member A
chr11_+_55319607 0.613 NM_001004735
OR5D14
olfactory receptor, family 5, subfamily D, member 14
chr6_+_79633907 0.611 NM_001010844
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr11_-_59369501 0.609 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr1_+_67404756 0.609 NM_144701
IL23R
interleukin 23 receptor
chr2_+_170370290 0.608 SSB
Sjogren syndrome antigen B (autoantigen La)
chr7_-_38279757 0.606 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr5_+_161427225 0.600 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr18_-_62422195 0.599 NM_021153
CDH19
cadherin 19, type 2
chr15_-_53349775 0.593 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr5_+_68549380 0.592 MRPS36
mitochondrial ribosomal protein S36
chr11_+_59027624 0.591 NM_001004706
OR4D11
olfactory receptor, family 4, subfamily D, member 11
chr3_+_188197029 0.590


chr13_-_45654296 0.588 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_119550402 0.586 CUL4B
cullin 4B
chr1_+_239762179 0.586 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_-_78831821 0.583 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr15_-_74963246 0.581 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr12_-_120591938 0.580 NM_173855
MORN3
MORN repeat containing 3
chr11_+_55554470 0.574 NM_001001921
OR5AS1
olfactory receptor, family 5, subfamily AS, member 1
chr3_-_147745111 0.573 NM_021105
PLSCR1
phospholipid scramblase 1
chr6_-_100123238 0.569 NM_001013399
NM_005190
CCNC

cyclin C

chr19_-_22171592 0.568 NM_001001411
ZNF676
zinc finger protein 676
chr1_-_181189127 0.566 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr6_+_12825022 0.563 PHACTR1
phosphatase and actin regulator 1
chrX_+_47114925 0.559 NM_003446
ZNF157
zinc finger protein 157
chr4_-_80548378 0.558 NM_033214
GK2
glycerol kinase 2
chr8_+_101232014 0.555 NM_005034
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr8_-_66863841 0.554 NM_002603
PDE7A
phosphodiesterase 7A
chr7_-_63660766 0.553 ZNF680
zinc finger protein 680
chr3_-_157755559 0.553 SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr1_+_160002746 0.553 ATF6
activating transcription factor 6
chr11_-_55994548 0.550 NM_001004742
OR5M3
olfactory receptor, family 5, subfamily M, member 3
chr21_-_39739528 0.547 LCA5L
Leber congenital amaurosis 5-like
chr7_+_71937980 0.547 SBDSP1
Shwachman-Bodian-Diamond syndrome pseudogene 1
chr3_+_173954940 0.547 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr12_+_32723539 0.544 DNM1L
dynamin 1-like
chr18_+_27152049 0.544 NM_001942
DSG1
desmoglein 1
chr2_-_197165495 0.542 NM_020760
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chrX_+_41433169 0.542 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr6_-_44341296 0.539 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_95298706 0.536 NM_001144663
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr13_-_45654327 0.535 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_26310253 0.532 NM_031418
ANO3
anoctamin 3
chr8_-_7710547 0.532 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chr12_-_51887318 0.532 ITGB7
integrin, beta 7
chr12_-_11230809 0.528 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr8_+_24207524 0.528 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr2_-_202192141 0.527 NM_001168216
NM_001168217
NM_001168221
NM_152525
ALS2CR11



amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11



chr15_+_70477707 0.526 NM_001080462
TMEM202
transmembrane protein 202
chr18_+_27925815 0.525 NM_016271
RNF138
ring finger protein 138
chr6_+_32713160 0.525 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_-_68511738 0.524 NM_001114387
NM_182606
TMPRSS11A

transmembrane protease, serine 11A

chr2_+_24660849 0.523 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr7_-_91632525 0.523 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chrX_-_111809929 0.522 NM_178175
LHFPL1
lipoma HMGIC fusion partner-like 1
chr12_-_10464308 0.522 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr5_+_179065282 0.517 CANX
calnexin
chr2_+_33514896 0.517 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_142369534 0.516 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr3_+_123779122 0.515 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr4_+_39874921 0.512 NM_004310
RHOH
ras homolog gene family, member H
chr12_+_21481804 0.511 NM_024854
PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr7_-_124357272 0.511 NM_001042594
NM_015450
POT1

protection of telomeres 1 homolog (S. pombe)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.14 3.27e-07 GO:0007606 sensory perception of chemical stimulus
2.18 1.23e-06 GO:0007608 sensory perception of smell
1.69 1.47e-04 GO:0007600 sensory perception
1.68 7.95e-04 GO:0006955 immune response
1.45 1.83e-02 GO:0002376 immune system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.22 2.49e-07 GO:0004984 olfactory receptor activity
1.72 4.92e-06 GO:0004930 G-protein coupled receptor activity
1.45 4.66e-05 GO:0004872 receptor activity
1.49 3.03e-04 GO:0004888 transmembrane receptor activity
1.32 4.95e-03 GO:0004871 signal transducer activity
1.32 4.95e-03 GO:0060089 molecular transducer activity