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• Activity deltas table
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Motif ID: ZBTB6.p2

Z-value: 1.390

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_149662640	1.581	NM_001012301	ARSI	arylsulfatase family, member I
chr12_-_51200347	1.430	NM_000424	KRT5	keratin 5
chr11_-_78829342	1.379	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr2_+_220017617	1.239		SPEG	SPEG complex locus
chr11_-_11987414	0.992		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr1_+_43769065	0.972	NM_002840 NM_130440	PTPRF	protein tyrosine phosphatase, receptor type, F
chr19_-_40693176	0.944	NM_001126059	DMKN	dermokine
chr3_-_62835601	0.927
chr22_-_37569962	0.918	NM_014293	NPTXR	neuronal pentraxin receptor
chr12_-_51132129	0.856	NM_005555	KRT6B	keratin 6B
chr11_-_11987458	0.852	NM_013253	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr6_+_43151922	0.846	NM_002821 NM_152880 NM_152881 NM_152882	PTK7	PTK7 protein tyrosine kinase 7
chr7_-_1465487	0.827		MICALL2	MICAL-like 2
chr19_+_2115119	0.766	NM_032482	DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr7_+_143683365	0.721	NM_005435	ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5
chr15_+_43209422	0.720	NM_017434 NM_175940	DUOX1	dual oxidase 1
chr4_+_30331289	0.708		PCDH7	protocadherin 7
chr1_+_116181927	0.669		NHLH2	nescient helix loop helix 2
chr1_-_226530350	0.664
chr4_+_30331543	0.658		PCDH7	protocadherin 7
chr19_+_59077241	0.657	NM_002739	PRKCG	protein kinase C, gamma
chr2_-_233060774	0.649	NM_004826	ECEL1	endothelin converting enzyme-like 1
chr16_-_66007650	0.638	NM_013304	ZDHHC1	zinc finger, DHHC-type containing 1
chr11_-_11987115	0.634		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr10_-_99780574	0.632	NM_018058	CRTAC1	cartilage acidic protein 1
chr12_-_51173238	0.632	NM_005554	KRT6A	keratin 6A
chr8_-_144694722	0.627		ZC3H3	zinc finger CCCH-type containing 3
chr10_+_101078784	0.625	NM_020348	CNNM1	cyclin M1
chr11_-_11987333	0.624		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr22_+_31527744	0.620		TIMP3	TIMP metallopeptidase inhibitor 3
chr2_-_217267742	0.614		IGFBP5	insulin-like growth factor binding protein 5
chr22_+_31527678	0.608		TIMP3	TIMP metallopeptidase inhibitor 3
chr1_+_182622850	0.607		C1orf21	chromosome 1 open reading frame 21
chr10_-_105604942	0.605	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr3_-_48445719	0.605	NM_002673	PLXNB1	plexin B1
chr11_+_75056343	0.599
chr11_-_11987198	0.592	NM_015881	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr2_-_235070431	0.591	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr17_-_7323667	0.587	NM_001128833	ZBTB4	zinc finger and BTB domain containing 4
chr16_-_4105703	0.587		ADCY9	adenylate cyclase 9
chrX_-_50230329	0.581	NM_001013742	DGKK	diacylglycerol kinase, kappa
chr1_-_32002222	0.578	NM_001703	BAI2	brain-specific angiogenesis inhibitor 2
chr11_+_46256161	0.577		CREB3L1	cAMP responsive element binding protein 3-like 1
chr22_-_19122047	0.572		SCARF2	scavenger receptor class F, member 2
chr6_-_33276416	0.570		RXRB	retinoid X receptor, beta
chr16_-_4106022	0.568		ADCY9	adenylate cyclase 9
chr11_+_46255737	0.566	NM_052854	CREB3L1	cAMP responsive element binding protein 3-like 1
chr1_-_1283770	0.557	NM_032348	MXRA8	matrix-remodelling associated 8
chr16_-_4604895	0.555	NM_145253	FAM100A	family with sequence similarity 100, member A
chr14_+_58174489	0.551	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr8_-_48813256	0.550	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr2_-_96899396	0.541	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr11_-_605998	0.536	NM_001572 NM_004029	IRF7	interferon regulatory factor 7
chr7_+_72720093	0.530	NM_001077621	VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr11_-_605920	0.525		IRF7	interferon regulatory factor 7
chr11_+_65414450	0.521	NM_006848	CCDC85B	coiled-coil domain containing 85B
chr10_+_99069007	0.517	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr11_-_35503720	0.517	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr9_-_130980359	0.513	NM_203434	IER5L	immediate early response 5-like
chr2_-_220116508	0.511	NM_024536	CHPF	chondroitin polymerizing factor
chr2_-_230287442	0.507	NM_139072	DNER	delta/notch-like EGF repeat containing
chr16_+_30952382	0.505	NM_004604	STX4	syntaxin 4
chrX_+_49531209	0.505	NM_001145073	USP27X	ubiquitin specific peptidase 27, X-linked
chrX_+_17303798	0.501		NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_+_1335067	0.499	NM_001452	FOXF2	forkhead box F2
chr11_-_65841077	0.498	NM_020404	CD248	CD248 molecule, endosialin
chr11_-_605649	0.497	NM_004031	IRF7	interferon regulatory factor 7
chr8_-_38444982	0.491		FGFR1	fibroblast growth factor receptor 1
chr9_-_90983195	0.490		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr1_+_156417302	0.489		CD1D	CD1d molecule
chr10_+_22580992	0.487
chr9_-_130980302	0.487		IER5L	immediate early response 5-like
chr11_+_65414677	0.480		CCDC85B	coiled-coil domain containing 85B
chr11_+_46256130	0.479		CREB3L1	cAMP responsive element binding protein 3-like 1
chr1_-_203557379	0.479	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chr11_+_63815348	0.478	NM_033310	KCNK4	potassium channel, subfamily K, member 4
chr11_-_6633427	0.478	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr7_-_5429702	0.475	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr19_+_45811316	0.471		LTBP4	latent transforming growth factor beta binding protein 4
chr22_-_45311730	0.467	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr3_+_52254782	0.463		PPM1M	protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr22_+_29819343	0.463		SMTN	smoothelin
chr19_+_63599268	0.463	NM_001195135	LOC646862	hypothetical protein LOC646862
chr12_+_6907646	0.462	NM_001940	ATN1	atrophin 1
chr17_-_45620911	0.461		COL1A1	collagen, type I, alpha 1
chr1_+_182622987	0.460		C1orf21	chromosome 1 open reading frame 21
chr2_+_223244606	0.459	NM_058165	MOGAT1	monoacylglycerol O-acyltransferase 1
chr20_-_61649259	0.455	NM_080823	SRMS	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
chr17_-_7323528	0.454		ZBTB4	zinc finger and BTB domain containing 4
chr17_-_39265705	0.454		MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr11_-_65139277	0.453		MAP3K11	mitogen-activated protein kinase kinase kinase 11
chr1_-_212791188	0.451		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr2_-_220144254	0.450		OBSL1	obscurin-like 1
chrX_+_17303727	0.449		NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr8_-_145187553	0.447	NM_017570	OPLAH	5-oxoprolinase (ATP-hydrolysing)
chr2_-_220116062	0.445	NM_001195731	CHPF	chondroitin polymerizing factor
chr7_+_74017015	0.441	NM_001145063	GATSL1 GATSL2	GATS protein-like 1 GATS protein-like 2
chr17_-_45633986	0.439	NM_000088	COL1A1	collagen, type I, alpha 1
chr16_-_4604781	0.438		FAM100A	family with sequence similarity 100, member A
chr18_+_40513889	0.437	NM_001130110	SETBP1	SET binding protein 1
chr19_-_4853878	0.437	NM_001080523	ARRDC5	arrestin domain containing 5
chr16_+_3036682	0.436	NM_022468	MMP25	matrix metallopeptidase 25
chr19_-_4351470	0.435	NM_003025	SH3GL1	SH3-domain GRB2-like 1
chrX_-_54538591	0.434		FGD1	FYVE, RhoGEF and PH domain containing 1
chr13_-_76358370	0.433		KCTD12	potassium channel tetramerisation domain containing 12
chr3_-_159306532	0.432	NM_001163678 NM_003030 NM_006884	SHOX2	short stature homeobox 2
chr16_-_71650034	0.431	NM_001164766	ZFHX3	zinc finger homeobox 3
chr8_-_133561738	0.431		KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr10_-_99084254	0.428		FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr1_+_27521308	0.427		TMEM222	transmembrane protein 222
chr19_-_54231884	0.426	NM_033377	CGB1 CGB2	chorionic gonadotropin, beta polypeptide 1 chorionic gonadotropin, beta polypeptide 2
chr14_-_102045849	0.425	NM_152326	ANKRD9	ankyrin repeat domain 9
chr17_+_7549138	0.424	NM_001406	EFNB3	ephrin-B3
chr7_+_72720256	0.423		VPS37D	vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr8_-_38444675	0.419		FGFR1	fibroblast growth factor receptor 1
chr16_-_4605003	0.417		FAM100A	family with sequence similarity 100, member A
chr16_+_65754788	0.417	NM_001040667 NM_001538	HSF4	heat shock transcription factor 4
chr5_+_140154627	0.411	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr19_+_45915122	0.404		ITPKC	inositol 1,4,5-trisphosphate 3-kinase C
chr11_-_62753574	0.404	NM_199352	SLC22A25	solute carrier family 22, member 25
chr19_+_59333232	0.402	NM_014516	CNOT3	CCR4-NOT transcription complex, subunit 3
chr11_+_129823667	0.401	NM_139055	ADAMTS15	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr1_+_224803123	0.399	NM_001003665	C1orf95	chromosome 1 open reading frame 95
chr6_-_37773609	0.397	NM_153487	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1
chr20_+_33750645	0.397	NM_080748	ROMO1	reactive oxygen species modulator 1
chr11_+_110916442	0.395	NM_178834	LAYN	layilin
chr11_+_63510478	0.395		OTUB1	OTU domain, ubiquitin aldehyde binding 1
chr10_-_103869923	0.395	NM_001113407	LDB1	LIM domain binding 1
chr17_-_45633873	0.394		COL1A1	collagen, type I, alpha 1
chr3_-_75566781	0.391		FAM86DP	family with sequence similarity 86, member D, pseudogene
chr2_-_128138435	0.389	NM_017980	LIMS2	LIM and senescent cell antigen-like domains 2
chr11_+_63510403	0.388		OTUB1	OTU domain, ubiquitin aldehyde binding 1
chr16_-_65838813	0.384		FHOD1	formin homology 2 domain containing 1
chr11_-_11986704	0.383	NM_001018057	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr8_-_144731646	0.383	NM_145201	NAPRT1	nicotinate phosphoribosyltransferase domain containing 1
chr5_+_135392482	0.382	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr2_+_26768894	0.381	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr8_+_68418622	0.381
chr19_-_11477395	0.380		ZNF653	zinc finger protein 653
chr14_+_73073570	0.379	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr16_-_65838894	0.379		FHOD1	formin homology 2 domain containing 1
chr12_-_51253875	0.378	NM_175053	KRT74	keratin 74
chr10_-_76829857	0.375		ZNF503	zinc finger protein 503
chr12_+_46133	0.374	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr11_-_3104413	0.374		OSBPL5	oxysterol binding protein-like 5
chr8_+_104582151	0.373	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr14_+_93710401	0.372	NM_020958 NM_058237	PPP4R4	protein phosphatase 4, regulatory subunit 4
chr12_+_48737753	0.371	NM_001095 NM_020039	ACCN2	amiloride-sensitive cation channel 2, neuronal
chr7_-_143622188	0.371		ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5
chr17_+_37942034	0.371
chr11_+_63808858	0.370	NM_001177358 NM_001170881	GPR137	G protein-coupled receptor 137
chr19_+_7801110	0.369	NM_145245	EVI5L	ecotropic viral integration site 5-like
chrX_+_12066505	0.368	NM_014728	FRMPD4	FERM and PDZ domain containing 4
chr4_-_916101	0.366		GAK	cyclin G associated kinase
chr1_+_182622751	0.365	NM_030806	C1orf21	chromosome 1 open reading frame 21
chr13_-_20533703	0.365	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr16_+_54782751	0.365	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr1_-_59020875	0.364		JUN	jun proto-oncogene
chr6_-_2916980	0.362		SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr14_+_104852225	0.362		PACS2	phosphofurin acidic cluster sorting protein 2
chr19_-_4351357	0.361		SH3GL1	SH3-domain GRB2-like 1
chr16_+_1696162	0.360	NM_001040439 NM_015133	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3
chr5_+_17270781	0.359		BASP1	brain abundant, membrane attached signal protein 1
chr17_+_37941715	0.357		NAGLU	N-acetylglucosaminidase, alpha
chr19_+_60816770	0.356	NM_001195605	ZNF865	zinc finger protein 865
chr19_-_14447163	0.355	NM_000955	PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa
chr18_-_43821491	0.354	NM_001039360	ZBTB7C	zinc finger and BTB domain containing 7C
chr9_-_129679760	0.353	NM_000476	AK1	adenylate kinase 1
chr16_+_31619415	0.353		KIAA0664L3	KIAA0664-like 3
chr11_-_64133908	0.353
chr11_-_64368616	0.352	NM_017525	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)
chr7_+_75928907	0.346	NM_001102594 NM_001102595 NM_020892	DTX2	deltex homolog 2 (Drosophila)
chr16_-_30929217	0.346	NM_052874	STX1B	syntaxin 1B
chr10_+_75343352	0.345		PLAU	plasminogen activator, urokinase
chr12_-_51153788	0.344	NM_173086	KRT6C	keratin 6C
chr17_-_39796649	0.344	NM_198475	FAM171A2	family with sequence similarity 171, member A2
chr19_+_1055614	0.343	NM_001039848	GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr19_+_63747638	0.343	NM_005762	TRIM28	tripartite motif containing 28
chr9_-_34448477	0.341	NM_001184940 NM_001184941 NM_001184942 NM_001184943 NM_001184944 NM_001184945 NM_147202	C9orf25	chromosome 9 open reading frame 25
chr9_-_21549696	0.341		LOC554202	hypothetical LOC554202
chr19_+_53559468	0.341	NM_012451	SYNGR4	synaptogyrin 4
chr17_+_45965044	0.340	NM_017957	EPN3	epsin 3
chr4_+_30330963	0.339	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr17_-_39437362	0.338	NM_004160	PYY	peptide YY
chr10_-_73203202	0.337	NM_022153	C10orf54	chromosome 10 open reading frame 54
chr19_+_45799060	0.336	NM_001042545	LTBP4	latent transforming growth factor beta binding protein 4
chr19_-_17306538	0.335	NM_020959	ANO8	anoctamin 8
chr17_+_3993166	0.332	NM_144611	CYB5D2	cytochrome b5 domain containing 2
chr10_+_72642274	0.331	NM_170744	UNC5B	unc-5 homolog B (C. elegans)
chr15_+_39573363	0.331	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr8_-_144731498	0.330		NAPRT1	nicotinate phosphoribosyltransferase domain containing 1
chr18_-_33399601	0.329		CELF4	CUGBP, Elav-like family member 4
chr6_-_33276426	0.328		RXRB	retinoid X receptor, beta
chr19_+_63747829	0.326		TRIM28	tripartite motif containing 28
chr5_+_135392624	0.326		TGFBI	transforming growth factor, beta-induced, 68kDa
chr17_+_37941790	0.326		NAGLU	N-acetylglucosaminidase, alpha
chr16_-_85146181	0.326	NM_001159380 NM_001159377 NM_001159378 NM_001159379 NM_022764	MTHFSD	methenyltetrahydrofolate synthetase domain containing
chr3_-_45162901	0.325	NM_022842 NM_178181	CDCP1	CUB domain containing protein 1
chr16_+_30952350	0.324		STX4	syntaxin 4
chr6_-_39398293	0.324	NM_001135105 NM_001135106 NM_001135107 NM_032115	KCNK16	potassium channel, subfamily K, member 16

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	1.51e-08	GO:0009987	cellular process
1.45	2.53e-07	GO:0007399	nervous system development
1.20	8.89e-04	GO:0023052	signaling
1.21	1.05e-03	GO:0007275	multicellular organismal development
1.20	1.37e-03	GO:0032502	developmental process
1.22	2.50e-03	GO:0048856	anatomical structure development
1.22	4.27e-03	GO:0048731	system development
1.26	6.56e-03	GO:0048869	cellular developmental process
1.42	1.10e-02	GO:0048699	generation of neurons
1.56	1.48e-02	GO:0019226	transmission of nerve impulse
1.56	1.48e-02	GO:0035637	multicellular organismal signaling
1.25	2.30e-02	GO:0030154	cell differentiation
1.39	2.38e-02	GO:0022008	neurogenesis
1.37	2.94e-02	GO:0006793	phosphorus metabolic process
1.37	2.94e-02	GO:0006796	phosphate metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.61	1.38e-05	GO:0030054	cell junction
1.27	1.12e-04	GO:0044459	plasma membrane part
1.64	8.31e-04	GO:0045202	synapse
1.61	2.07e-03	GO:0043005	neuron projection
1.38	8.21e-03	GO:0042995	cell projection
1.80	1.27e-02	GO:0030135	coated vesicle
1.15	1.66e-02	GO:0005886	plasma membrane
1.63	2.06e-02	GO:0044456	synapse part
1.84	3.10e-02	GO:0030136	clathrin-coated vesicle
2.17	3.72e-02	GO:0008021	synaptic vesicle
1.14	4.03e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.62	8.90e-04	GO:0004674	protein serine/threonine kinase activity
1.44	4.36e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.48	4.72e-03	GO:0004672	protein kinase activity
1.88	5.82e-03	GO:0005244	voltage-gated ion channel activity
1.88	5.82e-03	GO:0022832	voltage-gated channel activity
1.42	5.85e-03	GO:0016301	kinase activity
2.05	1.25e-02	GO:0005267	potassium channel activity