Motif ID: AR.p2

Z-value: 0.908


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARchrX_+_667054070.332.2e-01Click!


Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_149778869 1.331 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr7_+_149778815 1.109 GIMAP8
GTPase, IMAP family member 8
chr14_-_106084519 0.906 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_58538110 0.736 FAM107A
family with sequence similarity 107, member A
chr1_+_22852268 0.707 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr18_-_46600295 0.642 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr14_-_105763152 0.641 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr12_+_111900650 0.601 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr14_-_105997732 0.571 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105796665 0.569 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106202262 0.503 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr9_-_106401514 0.417 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr1_-_149004852 0.414 CTSS
cathepsin S
chr14_-_105657378 0.412 IGHV4-31
immunoglobulin heavy variable 4-31
chr1_-_149004879 0.401 CTSS
cathepsin S
chr2_-_56266408 0.389 LOC100129434
hypothetical LOC100129434
chr8_-_7427584 0.376 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr4_+_71713324 0.372 NM_031889
ENAM
enamelin
chr16_+_88207457 0.359 DPEP1
dipeptidase 1 (renal)
chr14_-_105862080 0.358 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr11_+_55362802 0.357 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr8_+_11877238 0.352 NM_001033017
DEFB135
defensin, beta 135
chr1_+_12108542 0.344 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr8_+_7656261 0.338 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr5_+_140605330 0.331 NM_018935
PCDHB15
protocadherin beta 15
chr14_-_106270497 0.323 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr8_-_7404643 0.316 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr14_-_106289751 0.316 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_-_155053124 0.309 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr1_-_20122638 0.295 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr7_-_131483925 0.294 PLXNA4
plexin A4
chr8_+_7610374 0.290 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr1_-_149004916 0.290 NM_004079
CTSS
cathepsin S
chr3_-_58538530 0.278 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr14_-_105644300 0.262 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106184988 0.262 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_8099307 0.255 NM_016378
VCX2
variable charge, X-linked 2
chr19_+_17499064 0.253 FAM129C
family with sequence similarity 129, member C
chr1_+_179269766 0.247 MR1
major histocompatibility complex, class I-related
chr8_+_7139945 0.246 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chrX_+_151833641 0.246 NM_001178106
NM_001178107
NM_001178108
NM_001178109
NM_001178110
NM_007150
ZNF185





zinc finger protein 185 (LIM domain)





chrX_-_6463158 0.245 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr3_+_52254782 0.241 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr11_+_74539679 0.241 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr8_+_7663908 0.237 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr11_-_7804094 0.223 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr2_-_108972048 0.219 EDAR
ectodysplasin A receptor
chr8_+_7648613 0.216 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr1_+_13367840 0.212 NM_001045480
PRAMEF17
PRAMEF16
PRAME family member 17
PRAME family member 16
chr3_+_185537969 0.200 NM_144635
FAM131A
family with sequence similarity 131, member A
chr4_-_41849333 0.187 BEND4
BEN domain containing 4
chr14_-_106064887 0.184 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr4_-_164614335 0.183 NM_032136
TKTL2
transketolase-like 2
chr2_-_231498184 0.182 NM_005683
GPR55
G protein-coupled receptor 55
chr21_-_34806373 0.182 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr19_+_60109319 0.180 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr9_+_94776538 0.162 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr1_-_27825633 0.158 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr12_+_21417068 0.155 NM_000415
IAPP
islet amyloid polypeptide
chr2_+_11190629 0.151 NM_182500
C2orf50
chromosome 2 open reading frame 50
chr1_-_200396354 0.144 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr9_-_116196505 0.137 NM_030767
AKNA
AT-hook transcription factor
chr16_-_66528235 0.136 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_10054492 0.136 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chrX_+_152682772 0.133 NM_001163257
NM_005393
PLXNB3

plexin B3

chr11_-_64284762 0.126 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr14_-_105623358 0.118 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_29187565 0.115 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr17_+_36599664 0.114 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr7_-_150576957 0.109 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr7_-_150576660 0.108 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_49789204 0.103 NM_001142407
NM_001142408
NM_001142417
NM_001142435
NM_003296
CRISP2




cysteine-rich secretory protein 2




chr19_-_59568483 0.103 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr4_+_8493396 0.102 NM_152544
METTL19
methyltransferase like 19
chr19_+_4742727 0.098 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr5_+_23543480 0.094 NM_020227
PRDM9
PR domain containing 9
chr4_+_1923629 0.090 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr8_+_7618022 0.090 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr9_+_126253243 0.089 NM_001161808
GPR144
G protein-coupled receptor 144
chr8_+_7633318 0.088 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chr1_-_200396328 0.087 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr15_+_83092525 0.086 ZNF592
zinc finger protein 592
chr22_-_37858871 0.078 CBX7
chromobox homolog 7
chrX_+_8392870 0.077 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr12_+_124115877 0.077 NM_023928
AACS
acetoacetyl-CoA synthetase
chr8_+_7132323 0.077 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr6_-_6265896 0.076 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr1_-_154727014 0.075 MEF2D
myocyte enhancer factor 2D
chr1_+_149395728 0.073 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr16_-_66535457 0.072 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr19_-_15252261 0.072 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr22_-_37480898 0.072 SUN2
Sad1 and UNC84 domain containing 2
chr20_-_36191623 0.071 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr19_+_6981593 0.071 NM_001136507
MBD3L5
methyl-CpG-binding domain protein 3-like 5-like
chr11_+_63730720 0.070 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr22_+_22363047 0.069 NM_153615
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr2_+_134728299 0.065 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr14_-_64416307 0.064 SPTB
spectrin, beta, erythrocytic
chr14_-_105589467 0.063 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr1_+_103999663 0.061 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr17_+_11726943 0.061 NM_004662
DNAH9
dynein, axonemal, heavy chain 9
chr17_-_77638264 0.060 FASN
fatty acid synthase
chr21_+_30886629 0.060 NM_181605
KRTAP6-3
keratin associated protein 6-3
chr1_+_20227480 0.058 PLA2G5
phospholipase A2, group V
chr12_+_13240868 0.057 NM_001423
EMP1
epithelial membrane protein 1
chr9_-_132759045 0.056 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr18_+_70317548 0.056 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chrX_-_117003310 0.055 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr6_-_6265874 0.054 F13A1
coagulation factor XIII, A1 polypeptide
chr9_-_124370576 0.053 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chr2_+_241193492 0.051 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr2_+_28572441 0.050 NM_001170585
NM_153021
PLB1

phospholipase B1

chr1_+_151655623 0.049 NM_176823
S100A7A
S100 calcium binding protein A7A
chr11_+_113165134 0.049 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr9_+_138966588 0.048 NM_178536
LCN12
lipocalin 12
chr16_-_727889 0.048 NARFL
nuclear prelamin A recognition factor-like
chr2_-_108972100 0.046 NM_022336
EDAR
ectodysplasin A receptor
chr1_+_1374931 0.045 NM_001039211
ATAD3C
ATPase family, AAA domain containing 3C
chr19_-_46626474 0.044 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr9_-_76692829 0.042 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr17_+_35425139 0.041 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr10_-_48426868 0.041 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr6_-_31007905 0.039 NM_205854
SFTA2
surfactant associated 2
chr1_-_155052562 0.039 NM_001161443
SH2D2A
SH2 domain containing 2A
chr10_+_102748062 0.038 LZTS2
leucine zipper, putative tumor suppressor 2
chr19_+_42033564 0.035 ZNF345
zinc finger protein 345
chr11_-_65395248 0.035 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr8_+_100094710 0.034 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr16_+_70117523 0.034 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr3_+_185515108 0.032 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr14_+_85069217 0.030


chr3_+_46423682 0.029 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr3_+_160269734 0.027 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr1_-_148249152 0.025 NM_020205
OTUD7B
OTU domain containing 7B
chr14_+_20537253 0.025 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr9_-_21340885 0.025 NM_021002
IFNA6
interferon, alpha 6
chr8_+_7124701 0.024 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr15_-_38185578 0.023 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr2_+_230989150 0.023 SP100
SP100 nuclear antigen
chr8_+_22909305 0.023 NM_001160037
RHOBTB2
Rho-related BTB domain containing 2
chr17_+_7264366 0.022 NM_199339
SPEM1
spermatid maturation 1
chr19_+_53189719 0.021 NM_022142
ELSPBP1
epididymal sperm binding protein 1
chr14_+_20226762 0.021 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chrX_+_37735013 0.020 NM_012274
CXorf27
chromosome X open reading frame 27
chr2_+_242225771 0.019 ATG4B
ATG4 autophagy related 4 homolog B (S. cerevisiae)
chr6_+_38798529 0.017 NM_001371
DNAH8
dynein, axonemal, heavy chain 8
chr14_-_73095396 0.015 NM_203309
HEATR4
HEAT repeat containing 4
chr4_+_41678469 0.015 NM_001029955
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr19_+_55164668 0.015 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr15_+_63701322 0.014 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr1_+_103999824 0.010 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr20_-_23679558 0.010 NM_001898
CST1
cystatin SN
chr5_-_176869943 0.010 NM_001144875
NM_001144876
DOK3

docking protein 3

chr7_-_94791670 0.008 PON1
paraoxonase 1
chr16_-_20246309 0.007 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr1_-_104040308 0.007 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr3_-_110517929 0.006 NM_138815
DPPA2
developmental pluripotency associated 2
chr22_-_41353575 0.006 CYB5R3
cytochrome b5 reductase 3
chr21_+_43024936 0.005 PDE9A
phosphodiesterase 9A
chr5_-_149446287 0.002 CSF1R
colony stimulating factor 1 receptor
chr1_-_171441234 0.002 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
22.24 2.76e-06 GO:0003823 antigen binding
18.83 7.08e-03 GO:0004623 phospholipase A2 activity