Motif ID: RORA.p2

Z-value: 0.584


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RORAchr15_-_586719290.485.7e-02Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_15999154 0.448 MYCNOS
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
chr7_+_101715137 0.346 SH2B2
SH2B adaptor protein 2
chr7_+_101715110 0.339 NM_020979
SH2B2
SH2B adaptor protein 2
chr3_-_126215069 0.318 HEG1
HEG homolog 1 (zebrafish)
chr15_+_38296920 0.307 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr6_-_112033752 0.303 TRAF3IP2
TRAF3 interacting protein 2
chr11_-_70350509 0.279 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr18_-_54447168 0.259 NM_052947
ALPK2
alpha-kinase 2
chr11_+_13255913 0.232 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255905 0.230 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255952 0.219 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255925 0.216 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr19_-_53832381 0.214 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_+_13255948 0.214 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255836 0.199 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr11_-_47572478 0.194 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr6_-_112033775 0.192 TRAF3IP2
TRAF3 interacting protein 2
chr3_+_9919295 0.188 NM_153483
IL17RE
interleukin 17 receptor E
chr6_+_43846735 0.183 VEGFA
vascular endothelial growth factor A
chr11_-_119514011 0.177 TRIM29
tripartite motif containing 29
chr1_-_233879617 0.174 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr5_-_154210341 0.174 C5orf4
chromosome 5 open reading frame 4
chr6_-_152664906 0.169 SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_-_52315390 0.167 A1CF
APOBEC1 complementation factor
chr6_+_15353681 0.166 JARID2
jumonji, AT rich interactive domain 2
chr2_+_219180821 0.157 PLCD4
phospholipase C, delta 4
chr3_-_127382051 0.156 ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr17_+_23394062 0.154 NLK
nemo-like kinase
chr1_-_41259973 0.146 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr6_+_4781330 0.142 NM_001143970
CDYL
chromodomain protein, Y-like
chr15_-_50051239 0.136 NM_138792
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr2_-_30883775 0.132 NM_144575
CAPN13
calpain 13
chr2_+_219180875 0.132 NM_032726
PLCD4
phospholipase C, delta 4
chr11_+_13255967 0.126 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr2_+_119416214 0.123 NM_006770
MARCO
macrophage receptor with collagenous structure
chr3_-_24511456 0.121 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr7_+_151792052 0.120 LOC100128822
hypothetical LOC100128822
chr14_-_90780604 0.119 NM_001177676
GPR68
G protein-coupled receptor 68
chr17_-_70554674 0.114 ATP5H
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
chr12_+_11694172 0.113 ETV6
ets variant 6
chr17_+_68672705 0.112 NM_001050
SSTR2
somatostatin receptor 2
chr16_-_1772572 0.110 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr17_-_36113502 0.110 NM_019016
KRT24
keratin 24
chr6_+_158654464 0.105 TULP4
tubby like protein 4
chr19_-_7604569 0.105 NM_174895
PCP2
Purkinje cell protein 2
chr2_-_154043403 0.099 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_+_37360144 0.099 TBC1D22B
TBC1 domain family, member 22B
chr10_+_102285690 0.099 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chrX_-_102661072 0.098 NM_080879
RAB40A
RAB40A, member RAS oncogene family
chr19_+_7607976 0.098 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr15_-_54322767 0.097 NM_022841
RFX7
regulatory factor X, 7
chr17_-_23721430 0.095 VTN
vitronectin
chr14_-_22825148 0.094 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr1_+_40635058 0.091 NM_001198980
SMAP2
small ArfGAP2
chr6_+_32229599 0.090 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr2_-_215711313 0.088 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr6_-_24491498 0.088 NM_001195610
DCDC2
doublecortin domain containing 2
chr10_-_71811353 0.086 NM_207119
LRRC20
leucine rich repeat containing 20
chr1_-_35692668 0.085 KIAA0319L
KIAA0319-like
chr9_-_115877104 0.084 AMBP
alpha-1-microglobulin/bikunin precursor
chr7_+_120756325 0.083 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr11_+_106967165 0.082 ELMOD1
ELMO/CED-12 domain containing 1
chrX_+_56772391 0.081 LOC550643
hypothetical LOC550643
chr8_+_120289735 0.081 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr4_+_155707089 0.080 FGB
fibrinogen beta chain
chr1_-_246869181 0.080 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr6_+_43845915 0.078 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376
VEGFA















vascular endothelial growth factor A















chr1_+_150749943 0.077 NM_178438
LCE5A
late cornified envelope 5A
chrX_+_150635162 0.076 NM_033085
FATE1
fetal and adult testis expressed 1
chr17_+_63346625 0.076 BPTF
bromodomain PHD finger transcription factor
chr22_-_31732648 0.075 NM_003490
NM_133633
SYN3

synapsin III

chr3_-_127382093 0.072 NM_012190
ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr1_+_46151845 0.072 MAST2
microtubule associated serine/threonine kinase 2
chr17_-_2250967 0.071 NM_020310
MNT
MAX binding protein
chr6_-_136889436 0.069 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr14_-_34661156 0.069 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr17_-_30414789 0.069 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr17_+_23393744 0.068 NM_016231
NLK
nemo-like kinase
chr17_-_3445873 0.066 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chrX_-_102418329 0.066 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr11_-_2116048 0.066 IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_+_102285562 0.063 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr10_-_100164877 0.062 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr12_-_51887266 0.061 NM_000889
ITGB7
integrin, beta 7
chr11_+_106967283 0.060 ELMOD1
ELMO/CED-12 domain containing 1
chr7_+_97574054 0.060 NM_014916
LMTK2
lemur tyrosine kinase 2
chr3_+_160473784 0.059 SCHIP1
schwannomin interacting protein 1
chrX_-_108611940 0.058 NM_001522
GUCY2F
guanylate cyclase 2F, retinal
chr11_+_33306652 0.057 HIPK3
homeodomain interacting protein kinase 3
chr14_-_89868006 0.057 NM_017970
NM_199043
C14orf102

chromosome 14 open reading frame 102

chr18_+_30327341 0.057 DTNA
dystrobrevin, alpha
chr16_-_15095590 0.057 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr15_-_41000100 0.055 NM_173500
TTBK2
tau tubulin kinase 2
chr7_+_134567270 0.054 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr2_+_170742900 0.054 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr6_+_43846372 0.053 VEGFA
vascular endothelial growth factor A
chr4_+_85723080 0.052 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr5_+_81636921 0.052 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr17_-_70554635 0.052 NM_001003785
NM_006356
ATP5H

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d

chr7_-_100124805 0.051 NM_022574
GIGYF1
GRB10 interacting GYF protein 1
chr16_+_16233979 0.050 NOMO2
NODAL modulator 2
chr16_-_21739231 0.050 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chrX_-_2892288 0.048 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr2_+_138975946 0.048


chr16_+_24174374 0.047 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr11_-_2116775 0.047 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_+_110968594 0.046 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr22_+_40286957 0.046 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr10_-_52315436 0.046 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr10_+_80735881 0.046


chr19_+_55013315 0.045 NM_030973
MED25
mediator complex subunit 25
chr4_-_151990061 0.043 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr1_+_17719405 0.043 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_55617328 0.042 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2
chr14_+_93562500 0.042 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr17_-_32730804 0.042 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr3_+_185520744 0.042 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr16_+_16233972 0.041 NOMO2
NODAL modulator 2
chr6_+_43845875 0.040 VEGFA
vascular endothelial growth factor A
chrX_-_57164575 0.040 NM_001006681
NM_001006682
NM_001006683
SPIN2B


spindlin family, member 2B


chr4_+_155703581 0.040 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr19_-_10352172 0.039 TYK2
tyrosine kinase 2
chr16_+_16233996 0.038 NOMO1
NODAL modulator 1
chr7_+_18501876 0.038 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr17_+_23747422 0.038 SARM1
sterile alpha and TIR motif containing 1
chr16_+_16233989 0.038 NOMO2
NODAL modulator 2
chr11_-_119104463 0.037 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr15_-_43209348 0.037 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr19_-_44518516 0.036 NM_004877
GMFG
glia maturation factor, gamma
chr13_-_26232777 0.036 NM_005288
GPR12
G protein-coupled receptor 12
chr16_+_1773004 0.036 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr4_-_120462705 0.036 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr12_+_54672766 0.036 RAB5B
RAB5B, member RAS oncogene family
chr16_+_16234008 0.036 NOMO1
NODAL modulator 1
chr6_+_37429776 0.035 RNF8
ring finger protein 8
chr3_-_123716454 0.034 KPNA1
karyopherin alpha 1 (importin alpha 5)
chr12_-_51887318 0.034 ITGB7
integrin, beta 7
chr2_+_38005875 0.033 NM_001170791
FAM82A1
family with sequence similarity 82, member A1
chr11_-_72057755 0.032 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr17_+_38250122 0.032 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr12_+_54910086 0.032 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr11_+_109468734 0.032 ZC3H12C
zinc finger CCCH-type containing 12C
chr12_+_25096472 0.032 NM_006152
LRMP
lymphoid-restricted membrane protein
chr16_+_16233955 0.031 NOMO2
NODAL modulator 2
chr19_-_16111695 0.031


chr6_+_43846155 0.030 VEGFA
vascular endothelial growth factor A
chrX_-_32083506 0.030 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr11_-_2116360 0.029 IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_51837608 0.029 NM_001085479
IQCF3
IQ motif containing F3
chr12_+_48765300 0.028 SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_+_28637247 0.028 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr15_-_50270856 0.028 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr17_+_7474128 0.028 SHBG
sex hormone-binding globulin
chr11_-_128567302 0.027 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr1_-_176205970 0.027 SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_+_37429800 0.027 RNF8
ring finger protein 8
chr8_-_72436832 0.026 EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_53534565 0.026 NM_058173
MUCL1
mucin-like 1
chr4_+_52612197 0.025 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr5_+_137716169 0.025 NM_016604
KDM3B
lysine (K)-specific demethylase 3B
chr2_-_138762909 0.025


chr14_-_19252330 0.025 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr12_+_54700955 0.025 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr13_-_102517196 0.024 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr8_-_120720200 0.022 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr14_-_22825072 0.022 HOMEZ
homeobox and leucine zipper encoding
chr11_+_55554470 0.022 NM_001001921
OR5AS1
olfactory receptor, family 5, subfamily AS, member 1
chr1_-_176205672 0.021 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr12_-_54497751 0.021 SARNP
SAP domain containing ribonucleoprotein
chr17_-_17426469 0.020 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chrX_-_33139349 0.019 NM_004006
DMD
dystrophin
chr10_-_21475493 0.019 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr6_-_155677254 0.018 TFB1M
transcription factor B1, mitochondrial
chr15_-_63457378 0.018 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr15_-_88095363 0.017 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr17_+_70554914 0.017 KCTD2
potassium channel tetramerisation domain containing 2
chr8_-_6407882 0.017 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr4_-_186969202 0.017 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr6_-_155677303 0.016 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr4_+_39084867 0.016 NM_175737
KLB
klotho beta
chr12_+_119617060 0.016


chr11_-_56067308 0.015 NM_001005245
OR5M11
olfactory receptor, family 5, subfamily M, member 11
chr1_-_157551072 0.015 NM_001004467
OR10J3
olfactory receptor, family 10, subfamily J, member 3
chr3_-_17716515 0.015 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr10_-_121286034 0.015 NM_002925
RGS10
regulator of G-protein signaling 10
chr9_-_35093189 0.014 STOML2
stomatin (EPB72)-like 2
chr1_+_227506751 0.014 NM_006542
SPHAR
S-phase response (cyclin related)
chr19_+_8814268 0.014 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr17_+_7495436 0.014 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr13_+_108046500 0.014 NM_015011
MYO16
myosin XVI
chr1_+_20269239 0.013 NM_000929
PLA2G5
phospholipase A2, group V
chr3_-_117647053 0.013 NM_002338
LSAMP
limbic system-associated membrane protein
chr15_+_100319349 0.013 LOC100134445
WASH1
WASH3P
hypothetical LOC100134445
WAS protein family homolog 1
WAS protein family homolog 3 pseudogene
chr17_+_29670171 0.013 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr15_-_74963246 0.013 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr11_+_2116486 0.013


chr17_+_37941790 0.012 NAGLU
N-acetylglucosaminidase, alpha
chr17_-_31332568 0.012 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr19_+_47073029 0.012 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr19_+_62483606 0.012 NM_006635
ZNF460
zinc finger protein 460

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
70.55 3.29e-03 GO:0034314 Arp2/3 complex-mediated actin nucleation
47.04 1.62e-02 GO:0045010 actin nucleation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
25.66 2.72e-02 GO:0071203 WASH complex

Nothing significant found in function category.