Motif ID: TBX4,5.p2

Z-value: 0.882


Transcription factors associated with TBX4,5.p2:

Gene SymbolEntrez IDGene Name
TBX4 9496 T-box 4
TBX5 6910 T-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBX4chr17_+_568845600.273.1e-01Click!
TBX5chr12_-_113330574-0.116.8e-01Click!


Activity profile for motif TBX4,5.p2.

activity profile for motif TBX4,5.p2


Sorted Z-values histogram for motif TBX4,5.p2

Sorted Z-values for motif TBX4,5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX4,5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_61204392 1.046 NM_006133
 DAGLA
diacylglycerol lipase, alpha
chr17_+_4621924 0.889 NM_003963
 TM4SF5
transmembrane 4 L six family member 5
chr12_+_130004404 0.717 NM_198827
 GPR133
G protein-coupled receptor 133
chr14_+_94148466 0.681 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr20_-_24987615 0.656 NM_032501
 ACSS1
acyl-CoA synthetase short-chain family member 1
chr15_+_88120592 0.605 NM_001039958
 MESP2
mesoderm posterior 2 homolog (mouse)
chr3_+_187813553 0.579 AHSG
alpha-2-HS-glycoprotein
chr17_-_6958282 0.522 NM_080914
 ASGR2
asialoglycoprotein receptor 2
chr12_+_56435042 0.518 NM_138396
 MARCH9
membrane-associated ring finger (C3HC4) 9
chr12_-_26877189 0.506 NM_002223
 ITPR2
inositol 1,4,5-triphosphate receptor, type 2
chr6_+_26476384 0.486 NM_001197246
 BTN3A2
butyrophilin, subfamily 3, member A2
chr22_-_49363711 0.483 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
 CPT1B





carnitine palmitoyltransferase 1B (muscle)





chr14_+_92188546 0.482 RIN3
Ras and Rab interactor 3
chr17_-_16816113 0.476 NM_012452
 TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr2_+_219453487 0.468 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A
chr20_+_61963009 0.451 NM_080622
 ABHD16B
abhydrolase domain containing 16B
chr17_+_64922420 0.450 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_168936125 0.442 NM_001122752
NM_005025
 SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr6_+_31651319 0.439 NM_000594
 TNF
tumor necrosis factor
chr2_+_171280046 0.438 NM_001003845
 SP5
Sp5 transcription factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
3.36 1.73e-02 GO:0001708 cell fate specification
2.02 3.78e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
2.00 7.17e-03 GO:0032582 negative regulation of gene-specific transcription
1.70 1.47e-03 GO:0032583 regulation of gene-specific transcription
1.61 3.76e-03 GO:0006935 chemotaxis
1.61 3.76e-03 GO:0042330 taxis
1.52 2.18e-04 GO:0040011 locomotion
1.51 4.36e-05 GO:0009605 response to external stimulus
1.38 1.58e-03 GO:0051239 regulation of multicellular organismal process
1.30 5.08e-03 GO:0048583 regulation of response to stimulus
1.25 4.08e-02 GO:0065008 regulation of biological quality
1.24 1.68e-05 GO:0023052 signaling
1.21 4.01e-03 GO:0007165 signal transduction
1.20 9.06e-04 GO:0051716 cellular response to stimulus
1.17 6.93e-06 GO:0050896 response to stimulus
1.15 1.80e-02 GO:0032501 multicellular organismal process
1.13 2.50e-04 GO:0065007 biological regulation
1.12 4.03e-03 GO:0050789 regulation of biological process
1.12 6.27e-03 GO:0050794 regulation of cellular process
1.07 4.24e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.43 4.63e-02 GO:0030426 growth cone
1.93 2.41e-02 GO:0005912 adherens junction
1.21 3.32e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.30 2.83e-03 GO:0003823 antigen binding
1.60 1.70e-05 GO:0043565 sequence-specific DNA binding
1.40 2.68e-03 GO:0001071 nucleic acid binding transcription factor activity
1.40 2.68e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 4.17e-02 GO:0005102 receptor binding
1.11 5.87e-03 GO:0005515 protein binding