Motif ID: ONECUT1,2.p2

Z-value: 1.431


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT2chr18_+_532537750.458.4e-02Click!
ONECUT1chr15_-_50869379-0.155.7e-01Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_74478405 2.798 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr6_+_28032997 2.713 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr5_+_180726874 2.164 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr1_-_611896 2.089 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr6_+_30238961 1.822 NM_033229
TRIM15
tripartite motif containing 15
chr1_+_357502 1.683 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr8_-_107023 1.656 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr7_+_151284396 1.225 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr15_-_100280784 1.124 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chrX_+_134803450 1.118 NM_018666
SAGE1
sarcoma antigen 1
chr5_+_159368733 1.078 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr7_-_112513379 1.074 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr7_-_100077072 1.043 NM_003227
TFR2
transferrin receptor 2
chr10_+_97749837 1.039 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr3_+_2528272 1.030 CNTN4
contactin 4
chr2_-_95514205 1.014 NM_001164464
TRIM43
TRIM43B
tripartite motif containing 43
tripartite motif containing 43B
chr19_+_61624 1.004 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr5_+_159368721 0.996 TTC1
tetratricopeptide repeat domain 1
chr22_+_22435207 0.982 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr1_+_196874867 0.967 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_+_120490054 0.943 C7orf58
chromosome 7 open reading frame 58
chr5_+_159368690 0.942 TTC1
tetratricopeptide repeat domain 1
chr11_-_5302157 0.919 NM_033180
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr4_+_187424111 0.912 NM_000128
F11
coagulation factor XI
chr17_-_64462976 0.908 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr7_-_86433139 0.891 NM_152748
KIAA1324L
KIAA1324-like
chr1_-_149611768 0.882 NM_003944
SELENBP1
selenium binding protein 1
chr18_-_28606839 0.874 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr16_-_20610078 0.831 NM_052956
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr8_-_108579270 0.831 NM_001146
ANGPT1
angiopoietin 1
chr1_-_51660328 0.823 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr11_+_123639909 0.811 NM_001005198
OR8G5
olfactory receptor, family 8, subfamily G, member 5
chr7_-_135263737 0.811 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr1_+_196874839 0.803 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_+_113280727 0.801 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chrX_+_30171768 0.801 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr22_+_21384862 0.794 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr13_-_45654292 0.763 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_111215343 0.753 NM_001040033
CD53
CD53 molecule
chr13_-_45654296 0.749 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr20_+_186376 0.741 NM_207469
DEFB132
defensin, beta 132
chr14_-_20098929 0.724 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr21_-_46849413 0.722 NM_006272
S100B
S100 calcium binding protein B
chr4_-_44348414 0.718 NM_182592
YIPF7
Yip1 domain family, member 7
chr6_-_138581319 0.711 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr6_+_132000134 0.700 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chrX_+_47114925 0.693 NM_003446
ZNF157
zinc finger protein 157
chr3_+_171022403 0.692 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr1_+_195213289 0.685 NM_030787
CFHR5
complement factor H-related 5
chr1_-_100003936 0.678 NM_001013660
FRRS1
ferric-chelate reductase 1
chr16_+_65868913 0.674 NM_015432
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr14_-_23117268 0.669 JPH4
junctophilin 4
chr3_-_168854395 0.669 WDR49
WD repeat domain 49
chr13_-_45654327 0.664 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_105511615 0.664 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr7_+_143423073 0.662 NM_001004135
OR2A12
olfactory receptor, family 2, subfamily A, member 12
chr19_-_55539769 0.660 NAPSB
napsin B aspartic peptidase pseudogene
chrX_-_142632181 0.646 NM_001009615
SPANXN2
SPANX family, member N2
chr1_+_196874759 0.644 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr4_-_100431093 0.640 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr17_+_38178999 0.637 VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr2_+_130703384 0.633


chr17_+_25292748 0.631 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr6_+_32003180 0.625 NM_000063
NM_001145903
C2

complement component 2

chr3_-_180452096 0.621 NM_014407
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr5_+_159546951 0.612 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chrX_-_133620103 0.604 NM_021796
PLAC1
placenta-specific 1
chr14_+_19513442 0.603 NM_001005486
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr6_-_137536412 0.596 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr12_-_52975777 0.588 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr4_-_145159889 0.581 NM_002100
GYPB
glycophorin B (MNS blood group)
chr1_-_151390050 0.580 NM_001014291
SPRR2G
small proline-rich protein 2G
chr6_+_32021831 0.579 CFB
complement factor B
chr2_+_172530120 0.578 HAT1
histone acetyltransferase 1
chr2_+_168383427 0.562 NM_020981
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_+_129693938 0.562 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr12_+_21417068 0.557 NM_000415
IAPP
islet amyloid polypeptide
chr14_+_87560646 0.552 LOC283587
hypothetical protein LOC283587
chr14_-_23117614 0.551 JPH4
junctophilin 4
chr11_+_59038961 0.546 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chr12_-_11230809 0.543 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr16_+_54782802 0.541 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr11_+_123625632 0.537 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr14_-_37133927 0.536 FOXA1
forkhead box A1
chr1_-_156923111 0.535 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_-_24827265 0.530 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr1_+_45250503 0.529 UROD
uroporphyrinogen decarboxylase
chr8_-_86477585 0.528 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr11_+_62893836 0.525 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr7_+_128795280 0.521 AHCYL2
adenosylhomocysteinase-like 2
chrX_-_123925343 0.519 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr7_-_23476497 0.511 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr6_+_64344307 0.509 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr9_-_124949033 0.498 STRBP
spermatid perinuclear RNA binding protein
chr11_-_55438633 0.494 NM_001001960
OR5W2
olfactory receptor, family 5, subfamily W, member 2
chr19_-_53187151 0.493 NM_001128326
BSPH1
binder of sperm protein homolog 1
chr11_+_5431213 0.484 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr6_+_69401660 0.482 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr1_+_45250388 0.478 NM_000374
UROD
uroporphyrinogen decarboxylase
chr11_+_125208420 0.477 NM_001144874
PATE4
prostate and testis expressed 4
chr7_-_13992351 0.471 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr17_-_6924227 0.471 NM_006344
NM_182906
CLEC10A

C-type lectin domain family 10, member A

chr19_+_9157269 0.468 NM_175883
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr15_-_62460622 0.461 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr18_+_27425727 0.460 NM_000371
TTR
transthyretin
chr19_+_40632456 0.459 NM_005306
FFAR2
free fatty acid receptor 2
chr11_-_40272239 0.458 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr7_-_121731721 0.457 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr20_-_33705244 0.456 NM_003915
CPNE1
copine I
chr4_+_157044296 0.453 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr6_+_29187565 0.450 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr13_+_27264779 0.447 NM_145657
GSX1
GS homeobox 1
chr5_+_42792676 0.444 NM_001134848
CCDC152
coiled-coil domain containing 152
chr6_+_57062974 0.444 ZNF451
zinc finger protein 451
chrX_-_131401319 0.443 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr3_+_144165470 0.442 U2SURP
U2 snRNP-associated SURP domain containing
chr11_-_55994548 0.442 NM_001004742
OR5M3
olfactory receptor, family 5, subfamily M, member 3
chr10_+_7785290 0.438 ITIH2
inter-alpha (globulin) inhibitor H2
chr14_-_37134050 0.438 FOXA1
forkhead box A1
chr7_+_104539548 0.437 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr15_-_70838703 0.436


chr1_+_246150942 0.435 NM_001005522
OR2T8
olfactory receptor, family 2, subfamily T, member 8
chr5_-_145503190 0.434 LARS
leucyl-tRNA synthetase
chr1_-_76170563 0.431 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr4_+_37638450 0.422 NM_006607
PTTG2
pituitary tumor-transforming 2
chr8_+_98772537 0.420 MTDH
metadherin
chr12_+_53178834 0.420 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr1_+_198263352 0.419 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr17_+_38178969 0.419 NM_032353
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr6_+_57062944 0.418 ZNF451
zinc finger protein 451
chr10_-_72215116 0.418 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr3_-_143230124 0.417 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr2_+_170074457 0.414 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr10_+_7785347 0.413 ITIH2
inter-alpha (globulin) inhibitor H2
chr3_-_172227461 0.411 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chrX_+_30143595 0.410 NM_002364
MAGEB2
melanoma antigen family B, 2
chr21_-_14501114 0.409 NM_198996
LIPI
lipase, member I
chr9_+_263025 0.409 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr14_+_57964148 0.401


chr2_-_88208650 0.398 NM_001443
FABP1
fatty acid binding protein 1, liver
chr6_+_34312906 0.396 HMGA1
high mobility group AT-hook 1
chr11_-_123799976 0.396 NM_001005196
OR8B4
olfactory receptor, family 8, subfamily B, member 4
chr6_+_20642665 0.395 NM_017774
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr7_+_86111155 0.395 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr12_-_52975823 0.395 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr8_-_15140162 0.392 NM_139167
SGCZ
sarcoglycan, zeta
chr17_-_64568641 0.392 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_-_198643885 0.392 ZNF281
zinc finger protein 281
chr9_+_101717278 0.392 STX17
syntaxin 17
chr2_+_95621492 0.390 NM_138800
TRIM43
tripartite motif containing 43
chr4_-_155731288 0.389 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chrX_+_46825179 0.383 RGN
regucalcin (senescence marker protein-30)
chr22_+_21053972 0.381


chr7_+_99263571 0.380 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr1_+_45250475 0.379 UROD
uroporphyrinogen decarboxylase
chr7_-_25234582 0.376 NM_022150
NPVF
neuropeptide VF precursor
chr6_-_161614962 0.375 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_+_34312979 0.375 HMGA1
high mobility group AT-hook 1
chr15_+_64787983 0.368 NM_001142861
SMAD6
SMAD family member 6
chr6_+_57062918 0.368 ZNF451
zinc finger protein 451
chr4_+_69716298 0.367 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr10_+_68355797 0.367 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr5_+_57823017 0.367 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr6_+_71192862 0.366 NM_001162529
FAM135A
family with sequence similarity 135, member A
chr17_-_53849929 0.361 NM_017763
RNF43
ring finger protein 43
chr14_+_18447521 0.359 NM_001013354
OR11H12
olfactory receptor, family 11, subfamily H, member 12
chr7_+_123353144 0.356 NM_001174045
NM_001174046
SPAM1

sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)

chr4_-_46421360 0.355 RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr6_+_57062848 0.355 ZNF451
zinc finger protein 451
chrX_+_110252960 0.353 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr10_-_64698831 0.352 NM_004241
JMJD1C
jumonji domain containing 1C
chr10_+_70152216 0.349 CCAR1
cell division cycle and apoptosis regulator 1
chr1_-_246912227 0.348 NM_001004734
OR14I1
olfactory receptor, family 14, subfamily I, member 1
chr1_+_246635918 0.347 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr1_-_77457664 0.346 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr2_-_21081694 0.344 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_236120844 0.341 NM_021186
ZP4
zona pellucida glycoprotein 4
chr4_-_151990061 0.338 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_+_21434818 0.337


chr11_+_55297489 0.336 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chr15_-_41300316 0.335 EPB42
erythrocyte membrane protein band 4.2
chr10_+_7785235 0.334 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr9_+_124172644 0.333 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_+_7785331 0.328 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785360 0.328 ITIH2
inter-alpha (globulin) inhibitor H2
chr19_-_44518516 0.325 NM_004877
GMFG
glia maturation factor, gamma
chr1_+_51855343 0.324 OSBPL9
oxysterol binding protein-like 9
chr5_+_139856688 0.324 ANKHD1
ankyrin repeat and KH domain containing 1
chr13_+_51334117 0.323 NM_031290
CCDC70
coiled-coil domain containing 70
chr11_+_22652894 0.323 NM_005256
GAS2
growth arrest-specific 2
chr16_+_29971971 0.321 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr7_+_23252926 0.317 GPNMB
glycoprotein (transmembrane) nmb
chr19_-_14646626 0.317 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr3_-_168580764 0.316 NM_024687
ZBBX
zinc finger, B-box domain containing
chr1_+_12325632 0.316 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr5_+_60969392 0.316 NM_173667
FLJ37543
hypothetical protein FLJ37543
chr1_-_198644111 0.315 ZNF281
zinc finger protein 281
chr1_+_40635058 0.314 NM_001198980
SMAP2
small ArfGAP2
chr2_+_161980865 0.312 NM_006593
TBR1
T-box, brain, 1
chr3_-_25654659 0.312 TOP2B
topoisomerase (DNA) II beta 180kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.04 3.65e-12 GO:0007608 sensory perception of smell
2.85 1.96e-11 GO:0007606 sensory perception of chemical stimulus
2.04 9.95e-07 GO:0007600 sensory perception
1.60 6.89e-05 GO:0003008 system process
1.65 3.14e-04 GO:0050877 neurological system process
1.26 1.54e-03 GO:0032501 multicellular organismal process
2.90 1.25e-02 GO:0002252 immune effector process
4.02 2.92e-02 GO:0072376 protein activation cascade

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.14 3.40e-13 GO:0004984 olfactory receptor activity
2.21 2.32e-10 GO:0004930 G-protein coupled receptor activity
1.87 8.78e-09 GO:0004888 transmembrane receptor activity
1.70 4.72e-08 GO:0004872 receptor activity
1.52 2.01e-05 GO:0004871 signal transducer activity
1.52 2.01e-05 GO:0060089 molecular transducer activity
4.72 6.62e-03 GO:0043498 cell surface binding