Motif ID: NFE2.p2

Z-value: 0.934


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2chr12_-_52980984-0.341.9e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_141041982 1.337 NM_022481
 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_+_76749199 1.317 NM_014903
 NAV3
neuron navigator 3
chr5_+_150000394 1.218 NM_001109974
NM_007286
 SYNPO

synaptopodin

chr5_-_141041933 1.107 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_6298284 0.937 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr5_+_35892747 0.883 NM_002185
 IL7R
interleukin 7 receptor
chr14_+_62740878 0.841 NM_020663
 RHOJ
ras homolog gene family, member J
chrX_+_99786044 0.809 SRPX2
sushi-repeat containing protein, X-linked 2
chr2_-_85494639 0.778 CAPG
capping protein (actin filament), gelsolin-like
chr11_-_102174102 0.775 NM_001145938
NM_002421
 MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr9_-_116920232 0.775 NM_002160
 TNC
tenascin C
chr18_+_59405513 0.754 NM_012397
 SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr10_-_102780840 0.752 PDZD7
PDZ domain containing 7
chr11_-_102174032 0.726 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr7_-_42243142 0.716 NM_000168
 GLI3
GLI family zinc finger 3
chr10_-_30064600 0.708 NM_003174
 SVIL
supervillin
chrX_-_15593074 0.706 NM_020665
 TMEM27
transmembrane protein 27
chr7_-_42243318 0.696 GLI3
GLI family zinc finger 3
chrX_+_12903145 0.693 NM_021109
NM_183049
 TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr11_-_65860450 0.693 NM_004292
 RIN1
Ras and Rab interactor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
3.44 9.50e-03 GO:0009612 response to mechanical stimulus
3.05 1.90e-02 GO:0031960 response to corticosteroid stimulus
2.05 2.07e-02 GO:0043086 negative regulation of catalytic activity
1.99 3.57e-02 GO:0051094 positive regulation of developmental process
1.92 4.43e-02 GO:0007599 hemostasis
1.85 1.69e-02 GO:0001932 regulation of protein phosphorylation
1.80 2.80e-02 GO:0042325 regulation of phosphorylation
1.78 3.37e-02 GO:0019220 regulation of phosphate metabolic process
1.78 3.37e-02 GO:0051174 regulation of phosphorus metabolic process
1.76 2.19e-04 GO:0051246 regulation of protein metabolic process
1.74 2.24e-02 GO:0031399 regulation of protein modification process
1.73 4.03e-02 GO:0006955 immune response
1.73 4.69e-02 GO:2000026 regulation of multicellular organismal development
1.72 9.88e-03 GO:0009611 response to wounding
1.71 2.26e-02 GO:0009888 tissue development
1.63 3.34e-02 GO:0032268 regulation of cellular protein metabolic process
1.62 3.35e-02 GO:0042981 regulation of apoptosis
1.61 4.54e-02 GO:0043067 regulation of programmed cell death
1.60 1.63e-02 GO:0050790 regulation of catalytic activity
1.58 4.42e-03 GO:0009966 regulation of signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
3.51 2.36e-02 GO:0005604 basement membrane
3.35 6.37e-04 GO:0044420 extracellular matrix part
2.68 2.90e-02 GO:0043235 receptor complex
2.54 1.39e-05 GO:0005578 proteinaceous extracellular matrix
2.25 2.05e-04 GO:0031012 extracellular matrix
1.86 2.11e-03 GO:0030054 cell junction
1.75 5.94e-05 GO:0044421 extracellular region part
1.63 2.03e-02 GO:0005626 insoluble fraction
1.49 3.97e-03 GO:0005856 cytoskeleton
1.45 2.63e-04 GO:0044459 plasma membrane part
1.36 3.33e-02 GO:0005576 extracellular region
1.30 4.30e-04 GO:0071944 cell periphery
1.29 5.71e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.97 7.47e-05 GO:0005126 cytokine receptor binding