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Motif ID: NFE2.p2

Z-value: 0.934

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_141041982	1.337	NM_022481	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_+_76749199	1.317	NM_014903	NAV3	neuron navigator 3
chr5_+_150000394	1.218	NM_001109974 NM_007286	SYNPO	synaptopodin
chr5_-_141041933	1.107		ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr11_-_6298284	0.937	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr5_+_35892747	0.883	NM_002185	IL7R	interleukin 7 receptor
chr14_+_62740878	0.841	NM_020663	RHOJ	ras homolog gene family, member J
chrX_+_99786044	0.809		SRPX2	sushi-repeat containing protein, X-linked 2
chr2_-_85494639	0.778		CAPG	capping protein (actin filament), gelsolin-like
chr11_-_102174102	0.775	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr9_-_116920232	0.775	NM_002160	TNC	tenascin C
chr18_+_59405513	0.754	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr10_-_102780840	0.752		PDZD7	PDZ domain containing 7
chr11_-_102174032	0.726		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr7_-_42243142	0.716	NM_000168	GLI3	GLI family zinc finger 3
chr10_-_30064600	0.708	NM_003174	SVIL	supervillin
chrX_-_15593074	0.706	NM_020665	TMEM27	transmembrane protein 27
chr7_-_42243318	0.696		GLI3	GLI family zinc finger 3
chrX_+_12903145	0.693	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr11_-_65860450	0.693	NM_004292	RIN1	Ras and Rab interactor 1
chr11_-_66898223	0.674	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr10_-_88720908	0.665		LOC100133190	hypothetical LOC100133190
chrX_-_10761729	0.662	NM_033290	MID1	midline 1 (Opitz/BBB syndrome)
chr19_+_43502380	0.659		KCNK6	potassium channel, subfamily K, member 6
chr19_+_43572679	0.656	NM_001039616 NM_001042522	SPRED3	sprouty-related, EVH1 domain containing 3
chr11_-_6633427	0.644	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr3_-_48607596	0.629	NM_000094	COL7A1	collagen, type VII, alpha 1
chr16_+_2023279	0.618		SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_-_85494664	0.604		CAPG	capping protein (actin filament), gelsolin-like
chr1_-_45045543	0.601	NM_001013632	TCTEX1D4	Tctex1 domain containing 4
chrX_+_99785818	0.599	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr18_+_19706979	0.598	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr18_+_59788242	0.596	NM_001031848 NM_002640 NM_198833	SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr1_+_17507276	0.593	NM_012387	PADI4	peptidyl arginine deiminase, type IV
chr14_-_95011790	0.587	NM_152592	C14orf49	chromosome 14 open reading frame 49
chr11_+_67107641	0.586	NM_000852	GSTP1	glutathione S-transferase pi 1
chr15_-_38417564	0.574		C15orf52	chromosome 15 open reading frame 52
chr16_-_3025542	0.555	NM_001103175	CCDC64B	coiled-coil domain containing 64B
chr20_-_1257782	0.549		SDCBP2	syndecan binding protein (syntenin) 2
chr1_-_89261021	0.547	NM_018284	GBP3	guanylate binding protein 3
chr17_+_21131940	0.534	NM_002756	MAP2K3	mitogen-activated protein kinase kinase 3
chrX_+_149282097	0.530	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr9_-_129381086	0.528	NM_001035534	FAM129B	family with sequence similarity 129, member B
chr2_+_132890616	0.526	NM_001508	GPR39	G protein-coupled receptor 39
chr7_+_22733290	0.521	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr5_-_149515613	0.519	NM_002609	PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr5_+_148501178	0.517	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr16_+_82544327	0.516	NM_182981	OSGIN1	oxidative stress induced growth inhibitor 1
chr10_+_134751398	0.512	NM_001083909	GPR123	G protein-coupled receptor 123
chr9_-_139042526	0.511	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr5_-_149515502	0.501		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr12_-_54646061	0.500	NM_006928	PMEL	premelanosome protein
chr1_-_6474346	0.493	NM_020631	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_-_53935648	0.485	NM_017805	RASIP1	Ras interacting protein 1
chr18_+_59593591	0.475	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr15_+_84021271	0.472	NM_144767	AKAP13	A kinase (PRKA) anchor protein 13
chr2_+_28469275	0.472	NM_005253	FOSL2	FOS-like antigen 2
chr5_+_176807931	0.471	NM_001174102	PRR7	proline rich 7 (synaptic)
chr11_+_67107852	0.463		GSTP1	glutathione S-transferase pi 1
chr1_-_115682374	0.463	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr12_-_51153788	0.463	NM_173086	KRT6C	keratin 6C
chr11_-_128399218	0.460	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr8_-_145097031	0.455	NM_201380	PLEC	plectin
chr1_+_152644471	0.448		IL6R	interleukin 6 receptor
chr19_-_40939756	0.442	NM_144617	HSPB6	heat shock protein, alpha-crystallin-related, B6
chr3_+_106568334	0.442	NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr1_+_81544432	0.442		LPHN2	latrophilin 2
chr1_+_151147646	0.441	NM_005547	IVL	involucrin
chr3_+_30622905	0.441	NM_001024847 NM_003242	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr5_-_149515331	0.441		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr12_-_15005761	0.436	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr3_+_120799411	0.435	NM_015900	PLA1A	phospholipase A1 member A
chr17_-_36928604	0.434	NM_002275	KRT15	keratin 15
chr1_+_148747208	0.432		ECM1	extracellular matrix protein 1
chr19_+_43486640	0.431	NM_033520	C19orf33	chromosome 19 open reading frame 33
chr7_-_128330615	0.430		KCP	kielin/chordin-like protein
chrX_-_53327473	0.428	NM_015075	IQSEC2	IQ motif and Sec7 domain 2
chr1_-_84237316	0.428	NM_024686	TTLL7	tubulin tyrosine ligase-like family, member 7
chr8_-_145088679	0.426	NM_201383	PLEC	plectin
chr22_-_43040063	0.425	NM_001099294	KIAA1644	KIAA1644
chr12_-_49897743	0.424		POU6F1	POU class 6 homeobox 1
chr4_-_87500398	0.423	NM_138980 NM_138982	MAPK10	mitogen-activated protein kinase 10
chr19_+_41322841	0.422		CAPNS1	calpain, small subunit 1
chr6_+_1556543	0.421		FOXC1	forkhead box C1
chr16_+_55199978	0.416	NM_005953	MT2A	metallothionein 2A
chr6_+_74462630	0.416		CD109	CD109 molecule
chr11_+_35117226	0.416		CD44	CD44 molecule (Indian blood group)
chr15_+_78520634	0.413		ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr11_-_65424434	0.412		FOSL1	FOS-like antigen 1
chr10_-_6059460	0.410	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chr8_-_122722674	0.405	NM_005328	HAS2	hyaluronan synthase 2
chr4_+_40953698	0.404		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr11_+_47386621	0.403	NM_001128225 NM_152264	SLC39A13	solute carrier family 39 (zinc transporter), member 13
chr9_+_35528890	0.401		RUSC2	RUN and SH3 domain containing 2
chr17_-_18848713	0.400	NM_001039999	FAM83G	family with sequence similarity 83, member G
chr2_+_28469172	0.399		FOSL2	FOS-like antigen 2
chr12_-_54522881	0.397	NM_002429	MMP19	matrix metallopeptidase 19
chr3_+_11153778	0.395	NM_001098213	HRH1	histamine receptor H1
chr12_-_90097384	0.394	NM_133503	DCN	decorin
chr16_+_56219802	0.391	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr9_-_139042416	0.391		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr3_+_49002285	0.389	NM_177938 NM_177939	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr19_+_41119861	0.389	NM_024509	LRFN3	leucine rich repeat and fibronectin type III domain containing 3
chr11_+_128068982	0.388	NM_002017	FLI1	Friend leukemia virus integration 1
chr11_-_65424436	0.388	NM_005438	FOSL1	FOS-like antigen 1
chr1_-_151788341	0.387	NM_002960	S100A3	S100 calcium binding protein A3
chr8_-_26780665	0.387		ADRA1A	adrenergic, alpha-1A-, receptor
chr11_+_48303047	0.387	NM_001004702	OR4C3	olfactory receptor, family 4, subfamily C, member 3
chr16_+_88515917	0.386	NM_001197181	TUBB3	tubulin, beta 3
chr7_+_100557098	0.386	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr1_+_148747110	0.385	NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr3_-_58175437	0.383	NM_004944	DNASE1L3	deoxyribonuclease I-like 3
chr11_-_65424385	0.383		FOSL1	FOS-like antigen 1
chr21_-_35181956	0.382		RUNX1	runt-related transcription factor 1
chr6_+_106653429	0.381	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr17_+_58058479	0.379	NM_006039	MRC2	mannose receptor, C type 2
chr15_+_72315719	0.379	NM_025055	CCDC33	coiled-coil domain containing 33
chr7_+_1543644	0.379		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr15_+_99276982	0.378	NM_024652	LRRK1	leucine-rich repeat kinase 1
chr22_-_43986896	0.377		KIAA0930	KIAA0930
chr21_-_35343331	0.376		RUNX1	runt-related transcription factor 1
chr16_-_73830480	0.375	NM_001170721	BCAR1	breast cancer anti-estrogen resistance 1
chr6_+_74462654	0.370		CD109	CD109 molecule
chr15_-_68971665	0.369	NM_020147	THAP10	THAP domain containing 10
chr6_+_41712907	0.366		MDFI	MyoD family inhibitor
chr17_-_7064092	0.365	NM_001365	DLG4	discs, large homolog 4 (Drosophila)
chr12_-_46439127	0.364	NM_001098531	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_7063625	0.363		DLG4	discs, large homolog 4 (Drosophila)
chr7_+_90177082	0.362		CDK14	cyclin-dependent kinase 14
chr6_+_74462226	0.361	NM_001159587 NM_001159588 NM_133493	CD109	CD109 molecule
chr1_-_161105174	0.359	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr11_+_62136788	0.358	NM_000327	ROM1	retinal outer segment membrane protein 1
chr3_-_48576204	0.357	NM_033199	UCN2	urocortin 2
chr9_+_35528628	0.356	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr7_+_1536847	0.353	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr11_+_101488380	0.352	NM_001195045	YAP1	Yes-associated protein 1
chr11_+_19328846	0.352	NM_001111018	NAV2	neuron navigator 2
chr16_+_4370879	0.352		VASN	vasorin
chr2_-_219566364	0.352	NM_005209 NM_057093 NM_057094	CRYBA2	crystallin, beta A2
chr1_-_17180659	0.351	NM_001135247 NM_017459	MFAP2	microfibrillar-associated protein 2
chr16_+_15503623	0.351	NM_001142469	C16orf45	chromosome 16 open reading frame 45
chr11_+_128069203	0.351		FLI1	Friend leukemia virus integration 1
chr2_+_28469199	0.350		FOSL2	FOS-like antigen 2
chr16_+_55684031	0.346		CPNE2	copine II
chr20_-_1257809	0.346	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr9_+_130942029	0.345		PPP2R4	protein phosphatase 2A activator, regulatory subunit 4
chr22_-_28972683	0.345	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr11_-_89248832	0.338	NM_001164397	TRIM64B	tripartite motif containing 64B
chr16_+_31274030	0.337		ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chrX_-_19727828	0.337	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr9_-_101621964	0.337
chr19_-_3920736	0.336	NM_001348	DAPK3	death-associated protein kinase 3
chr14_-_104507862	0.335		AHNAK2	AHNAK nucleoprotein 2
chr3_-_115826481	0.335	NM_001164346	ZBTB20	zinc finger and BTB domain containing 20
chr17_+_77261401	0.333	NM_004712	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr19_+_12996368	0.330		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_176205672	0.329	NM_033127	SEC16B	SEC16 homolog B (S. cerevisiae)
chr1_+_152644292	0.328	NM_000565 NM_181359	IL6R	interleukin 6 receptor
chr18_+_41560915	0.327	NM_001146037	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr1_+_36394338	0.324	NM_018067	MAP7D1	MAP7 domain containing 1
chr18_+_59705918	0.323	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr3_+_106568243	0.323		ALCAM	activated leukocyte cell adhesion molecule
chr16_-_2848106	0.322	NM_022119	PRSS22	protease, serine, 22
chr17_-_35975227	0.321	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr11_+_47386707	0.320		SLC39A13	solute carrier family 39 (zinc transporter), member 13
chr21_-_35343448	0.320		RUNX1	runt-related transcription factor 1
chr9_-_34652629	0.319	NM_006664	CCL27	chemokine (C-C motif) ligand 27
chr14_+_22422270	0.318	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr13_+_52500830	0.317	NM_006418	OLFM4	olfactomedin 4
chr4_-_68678181	0.317	NM_207407	TMPRSS11F	transmembrane protease, serine 11F
chr9_-_35101534	0.316		KIAA1539	KIAA1539
chr10_+_115302767	0.315	NM_004132	HABP2	hyaluronan binding protein 2
chr10_-_99521701	0.314	NM_003015	SFRP5	secreted frizzled-related protein 5
chr17_-_35911340	0.311	NM_032865	TNS4	tensin 4
chrX_-_110400406	0.311	NM_014289	CAPN6	calpain 6
chr19_+_12996830	0.310		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr6_+_74462577	0.309		CD109	CD109 molecule
chr14_+_78815406	0.309	NM_001105250 NM_138970	NRXN3	neurexin 3
chr17_-_36877002	0.308	NM_002278	KRT32	keratin 32
chr1_+_27541086	0.308		SYTL1	synaptotagmin-like 1
chr17_+_18566060	0.307	NM_001037330	TRIM16L	tripartite motif containing 16-like
chr2_-_73170290	0.306		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr10_-_29963906	0.306	NM_021738	SVIL	supervillin
chr3_-_115825742	0.304	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr1_+_168381811	0.303	NM_001136107	METTL11B	methyltransferase like 11B
chr12_+_54611212	0.301	NM_001345	DGKA	diacylglycerol kinase, alpha 80kDa
chr1_+_152644668	0.298		IL6R	interleukin 6 receptor
chr1_+_109827975	0.297	NM_153340	ATXN7L2	ataxin 7-like 2
chrX_+_47326594	0.295	NM_003254	TIMP1	TIMP metallopeptidase inhibitor 1
chr11_+_35154775	0.293		CD44	CD44 molecule (Indian blood group)
chr7_-_1465487	0.291		MICALL2	MICAL-like 2
chr17_+_58058774	0.291		MRC2	mannose receptor, C type 2
chr16_+_66128843	0.290	NM_001193524	FAM65A	family with sequence similarity 65, member A
chr17_-_31231421	0.290	NM_002985	CCL5	chemokine (C-C motif) ligand 5
chr11_+_5916033	0.288
chr21_-_35343065	0.287		RUNX1	runt-related transcription factor 1
chr7_-_98305599	0.284	NM_001134450 NM_001134451 NM_152913	TMEM130	transmembrane protein 130
chr21_+_46367216	0.284		COL6A2	collagen, type VI, alpha 2
chr12_-_53099269	0.283		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_187744808	0.282	NM_017541	CRYGS	crystallin, gamma S

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.76	2.19e-04	GO:0051246	regulation of protein metabolic process
1.46	5.20e-04	GO:0048522	positive regulation of cellular process
1.42	1.22e-03	GO:0048518	positive regulation of biological process
1.54	3.17e-03	GO:0023051	regulation of signaling
1.49	3.92e-03	GO:0048583	regulation of response to stimulus
1.58	4.42e-03	GO:0009966	regulation of signal transduction
1.34	6.45e-03	GO:0007165	signal transduction
1.22	8.68e-03	GO:0050896	response to stimulus
3.44	9.50e-03	GO:0009612	response to mechanical stimulus
1.72	9.88e-03	GO:0009611	response to wounding
1.60	1.63e-02	GO:0050790	regulation of catalytic activity
1.85	1.69e-02	GO:0001932	regulation of protein phosphorylation
3.05	1.90e-02	GO:0031960	response to corticosteroid stimulus
2.05	2.07e-02	GO:0043086	negative regulation of catalytic activity
1.74	2.24e-02	GO:0031399	regulation of protein modification process
1.71	2.26e-02	GO:0009888	tissue development
1.80	2.80e-02	GO:0042325	regulation of phosphorylation
1.63	3.34e-02	GO:0032268	regulation of cellular protein metabolic process
1.62	3.35e-02	GO:0042981	regulation of apoptosis
1.78	3.37e-02	GO:0019220	regulation of phosphate metabolic process
1.78	3.37e-02	GO:0051174	regulation of phosphorus metabolic process
1.99	3.57e-02	GO:0051094	positive regulation of developmental process
1.29	3.59e-02	GO:0023052	signaling
1.73	4.03e-02	GO:0006955	immune response
1.92	4.43e-02	GO:0007599	hemostasis
1.61	4.54e-02	GO:0043067	regulation of programmed cell death
1.73	4.69e-02	GO:2000026	regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.54	1.39e-05	GO:0005578	proteinaceous extracellular matrix
1.75	5.94e-05	GO:0044421	extracellular region part
2.25	2.05e-04	GO:0031012	extracellular matrix
1.45	2.63e-04	GO:0044459	plasma membrane part
1.30	4.30e-04	GO:0071944	cell periphery
1.29	5.71e-04	GO:0005886	plasma membrane
3.35	6.37e-04	GO:0044420	extracellular matrix part
1.86	2.11e-03	GO:0030054	cell junction
1.49	3.97e-03	GO:0005856	cytoskeleton
1.63	2.03e-02	GO:0005626	insoluble fraction
3.51	2.36e-02	GO:0005604	basement membrane
2.68	2.90e-02	GO:0043235	receptor complex
1.36	3.33e-02	GO:0005576	extracellular region

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.97	7.47e-05	GO:0005126	cytokine receptor binding