Motif ID: BACH2.p2

Z-value: 1.097


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BACH2chr6_-_91063181-0.029.5e-01Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_37022465 1.542 NM_005557
KRT16
keratin 16
chr11_-_117640196 1.450 MPZL2
myelin protein zero-like 2
chr11_+_384238 1.356 PKP3
plakophilin 3
chr11_+_384199 1.147 NM_007183
PKP3
plakophilin 3
chr11_-_117640407 1.073 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr3_-_48576204 1.016 NM_033199
UCN2
urocortin 2
chr17_-_36996611 0.982 NM_000526
KRT14
keratin 14
chr11_-_117640078 0.964


chr11_-_117640166 0.960 MPZL2
myelin protein zero-like 2
chr2_+_113591940 0.897 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr19_-_48661563 0.876 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr9_-_106705780 0.820 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr3_-_152517204 0.791 NM_023915
GPR87
G protein-coupled receptor 87
chr11_-_119499188 0.786 TRIM29
tripartite motif containing 29
chr11_+_12265022 0.778 NM_032867
MICALCL
MICAL C-terminal like
chr16_+_56219802 0.761 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr16_+_55199978 0.741 NM_005953
MT2A
metallothionein 2A
chr12_+_54760153 0.717 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr19_+_7859380 0.690 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr12_-_51629874 0.682 KRT8
keratin 8
chr3_-_48607596 0.674 NM_000094
COL7A1
collagen, type VII, alpha 1
chr8_-_144887876 0.667 NM_198488
FAM83H
family with sequence similarity 83, member H
chr17_+_71229151 0.665 ITGB4
integrin, beta 4
chr18_+_19706979 0.653 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr17_+_71229110 0.651 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr8_+_120289735 0.624 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_-_188936941 0.618 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr1_+_221955876 0.604 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr3_-_12775718 0.597 NM_018306
TMEM40
transmembrane protein 40
chr1_+_181421984 0.594 LAMC2
laminin, gamma 2
chr3_+_11153778 0.592 NM_001098213
HRH1
histamine receptor H1
chr20_-_1257782 0.581 SDCBP2
syndecan binding protein (syntenin) 2
chr6_+_32229278 0.571 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr6_+_31190505 0.543 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_+_71229191 0.536 ITGB4
integrin, beta 4
chr19_-_56215084 0.535 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr1_-_156923111 0.528 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_116099648 0.525 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr1_+_3378030 0.522 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr2_+_47449790 0.521 NM_002354
EPCAM
epithelial cell adhesion molecule
chr12_-_56445653 0.514 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr2_+_47449951 0.503 EPCAM
epithelial cell adhesion molecule
chr9_-_129381086 0.503 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr7_-_1465487 0.493 MICALL2
MICAL-like 2
chr12_+_54760211 0.489 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr3_-_197549640 0.484 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr19_+_55398680 0.471 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr1_-_207891264 0.464 NM_001017402
LAMB3
laminin, beta 3
chr7_-_96177010 0.452 SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr15_+_57691272 0.443 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_891739 0.436 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr7_-_107430566 0.428 NM_002291
LAMB1
laminin, beta 1
chr9_+_131291224 0.426 LOC100506190
hypothetical LOC100506190
chr19_-_43955984 0.424 NM_002307
LGALS7
LGALS7B
lectin, galactoside-binding, soluble, 7
lectin, galactoside-binding, soluble, 7B
chrX_+_30143595 0.415 NM_002364
MAGEB2
melanoma antigen family B, 2
chr1_-_151788341 0.414 NM_002960
S100A3
S100 calcium binding protein A3
chrX_+_133198742 0.413 NM_001101357
CCDC160
coiled-coil domain containing 160
chr2_-_73170290 0.409 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr18_+_59295123 0.404 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr8_-_27528215 0.398 NM_001831
CLU
clusterin
chr20_+_42463387 0.397 HNF4A
hepatocyte nuclear factor 4, alpha
chr13_+_96592051 0.395 MBNL2
muscleblind-like 2 (Drosophila)
chr16_+_88515917 0.387 NM_001197181
TUBB3
tubulin, beta 3
chr1_+_181422016 0.377 LAMC2
laminin, gamma 2
chr2_+_87536106 0.377 NCRNA00152
non-protein coding RNA 152
chr5_+_145297490 0.371 SH3RF2
SH3 domain containing ring finger 2
chr1_+_15128882 0.367 NM_001018001
KAZN
kazrin, periplakin interacting protein
chr1_-_6474346 0.356 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_-_40696393 0.355 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr19_+_43486640 0.352 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr7_+_30927439 0.348 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr22_+_21340757 0.346


chr4_+_74825138 0.345 NM_000584
IL8
interleukin 8
chr15_+_57691382 0.343 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr21_-_35343065 0.340 RUNX1
runt-related transcription factor 1
chr9_-_34652629 0.339 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr6_+_41712907 0.333 MDFI
MyoD family inhibitor
chr7_-_7724762 0.333 NM_002947
RPA3
replication protein A3, 14kDa
chr6_-_31812251 0.332 CLIC1
chloride intracellular channel 1
chr1_-_6585485 0.331 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr19_-_40673185 0.330 NM_207392
KRTDAP
keratinocyte differentiation-associated protein
chr4_-_191143017 0.328 NM_020040
TUBB4Q
tubulin, beta polypeptide 4, member Q
chr3_+_185386664 0.327 ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr6_-_31812266 0.327 CLIC1
chloride intracellular channel 1
chr2_+_87536174 0.324 NCRNA00152
non-protein coding RNA 152
chr6_-_31812283 0.320 CLIC1
chloride intracellular channel 1
chr6_-_31812072 0.317 CLIC1
chloride intracellular channel 1
chr12_-_49689255 0.317 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_+_181421796 0.314 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr16_-_28515195 0.312 NM_177528
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr9_+_131291144 0.312


chr4_-_658035 0.312 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr1_+_148747208 0.312 ECM1
extracellular matrix protein 1
chr1_-_108032645 0.310 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr18_+_54039818 0.307 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_244647333 0.306 NM_022743
SMYD3
SET and MYND domain containing 3
chr11_-_47164001 0.305 NM_001184975
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr4_+_152549776 0.305 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr6_+_32021687 0.303 NM_001710
CFB
complement factor B
chr3_+_185386556 0.303 NM_018358
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr6_-_31812049 0.300 CLIC1
chloride intracellular channel 1
chr6_-_134538526 0.297 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_31812214 0.297 CLIC1
chloride intracellular channel 1
chr20_-_51633042 0.296 NM_006526
ZNF217
zinc finger protein 217
chr20_-_1257809 0.296 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr8_-_17797127 0.294 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr7_-_150352484 0.294 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr4_-_89299034 0.292 NM_004827
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr21_-_35343331 0.291 RUNX1
runt-related transcription factor 1
chr12_+_50631704 0.291 NM_004302
NM_020328
ACVR1B

activin A receptor, type IB

chr21_-_35343448 0.290 RUNX1
runt-related transcription factor 1
chr17_+_7063873 0.288 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr11_-_102219450 0.288 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr13_+_112746908 0.287 MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_-_411995 0.287 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr16_-_2848106 0.283 NM_022119
PRSS22
protease, serine, 22
chr1_+_151270301 0.282 NM_003125
SPRR1B
small proline-rich protein 1B
chr9_+_102231616 0.277 NM_001198806
C9orf30
chromosome 9 open reading frame 30
chr17_+_69941430 0.276 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_-_31853027 0.276 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr6_+_47774247 0.274 NM_153838
GPR115
G protein-coupled receptor 115
chr10_+_121401076 0.272 BAG3
BCL2-associated athanogene 3
chr2_-_65447267 0.272 SPRED2
sprouty-related, EVH1 domain containing 2
chr10_+_85889164 0.271 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr12_-_7935010 0.270 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr8_-_27528105 0.270 CLU
clusterin
chr20_+_43468617 0.270 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr1_-_202387532 0.269 ETNK2
ethanolamine kinase 2
chr6_+_30983941 0.266 NM_001517
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
chr22_+_21053972 0.263


chr17_-_36165050 0.262 NM_181534
KRT25
keratin 25
chr3_-_197549588 0.261 TM4SF19
transmembrane 4 L six family member 19
chr10_+_121400926 0.261 BAG3
BCL2-associated athanogene 3
chr18_+_258147 0.260


chr12_+_50631734 0.257 ACVR1B
activin A receptor, type IB
chr3_+_57069508 0.254 NM_181727
SPATA12
spermatogenesis associated 12
chr1_-_6585268 0.254 KLHL21
kelch-like 21 (Drosophila)
chr3_-_195571748 0.254 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr6_-_31812260 0.252 CLIC1
chloride intracellular channel 1
chr18_+_59593591 0.251 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr17_+_71892538 0.251 SPHK1
sphingosine kinase 1
chr11_-_65860450 0.250 NM_004292
RIN1
Ras and Rab interactor 1
chr7_-_158304062 0.248 ESYT2
extended synaptotagmin-like protein 2
chr17_-_53335748 0.247 NM_017949
CUEDC1
CUE domain containing 1
chr12_-_46438447 0.246 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr6_+_32021742 0.245 CFB
complement factor B
chr16_+_29984647 0.245 ALDOA
aldolase A, fructose-bisphosphate
chr11_-_65424434 0.244 FOSL1
FOS-like antigen 1
chr18_+_54039779 0.241 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_84197463 0.241 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr9_-_106705867 0.240 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_65447370 0.240 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr10_+_121400881 0.240 BAG3
BCL2-associated athanogene 3
chr7_+_150319076 0.237 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr18_+_54039730 0.237 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_35996794 0.236 SRPK1
SRSF protein kinase 1
chr22_+_21393107 0.236 IGLJ3
immunoglobulin lambda joining 3
chr7_+_99485352 0.235 NM_145914
ZSCAN21
zinc finger and SCAN domain containing 21
chr11_-_102250876 0.233 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr3_+_189413414 0.233 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_38355949 0.231


chr10_-_95350949 0.230 NM_006744
RBP4
retinol binding protein 4, plasma
chr22_+_19191884 0.229 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr12_-_38123027 0.228 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chr17_+_71893014 0.227 SPHK1
sphingosine kinase 1
chr19_+_54068300 0.225 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr10_+_121400741 0.223 NM_004281
BAG3
BCL2-associated athanogene 3
chr19_+_61039755 0.222 NM_134444
NLRP4
NLR family, pyrin domain containing 4
chr1_+_221966684 0.222 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr14_-_93924663 0.222 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr12_+_121180439 0.222 MLXIP
MLX interacting protein
chr22_+_19699441 0.221 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr20_+_41621119 0.220 SGK2
serum/glucocorticoid regulated kinase 2
chr8_-_59734801 0.219 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr6_+_43705254 0.217 NM_001003690
MAD2L1BP
MAD2L1 binding protein
chr6_-_138470160 0.215 NM_022121
PERP
PERP, TP53 apoptosis effector
chr1_+_221966835 0.213 CAPN2
calpain 2, (m/II) large subunit
chr9_-_124030770 0.211 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr9_-_90983195 0.210 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr21_-_35343500 0.209 RUNX1
runt-related transcription factor 1
chr20_+_4614796 0.209 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr20_+_42463279 0.208 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr7_+_48094750 0.207 NM_181597
UPP1
uridine phosphorylase 1
chr19_+_43971689 0.207 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr14_-_24173205 0.207 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr16_-_46823682 0.206 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr6_-_31812297 0.205 NM_001288
CLIC1
chloride intracellular channel 1
chr17_+_72827227 0.203 SEPT9
septin 9
chr10_+_24795465 0.203 KIAA1217
KIAA1217
chr14_-_60260211 0.203 NM_017420
SIX4
SIX homeobox 4
chr10_-_85154 0.199 NM_177987
TUBB8
tubulin, beta 8
chr1_+_27591738 0.199 NM_005281
GPR3
G protein-coupled receptor 3
chr10_+_24795446 0.197 KIAA1217
KIAA1217
chr14_-_20642214 0.195


chr1_-_115682374 0.194 NM_002506
NGF
nerve growth factor (beta polypeptide)
chr8_-_59734474 0.193 NM_001144772
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr2_+_36777336 0.193 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr17_+_71892781 0.192 NM_001142602
SPHK1
sphingosine kinase 1
chrX_+_41078787 0.191 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr7_+_128219307 0.191 NM_022742
CCDC136
coiled-coil domain containing 136

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
6.66 3.06e-02 GO:0007044 cell-substrate junction assembly

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 6.37e-03 GO:0005737 cytoplasm
4.07 2.13e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 2.51e-03 GO:0005515 protein binding