Motif ID: TEAD1.p2

Z-value: 4.430


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_129173690.911.2e-06Click!
TEAD4chr12_+_29387030.853.3e-05Click!
TEAD2chr19_-_545574500.165.6e-01Click!
TEAD3chr6_-_355726940.078.0e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_132314004 9.323 NM_001901
 CTGF
connective tissue growth factor
chr19_+_39664706 8.956 NM_001080436
 WTIP
Wilms tumor 1 interacting protein
chr1_-_212791597 8.621 NM_005401
 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr3_-_135575925 8.551 NM_016201
 AMOTL2
angiomotin like 2
chr1_-_212791467 7.842 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr15_+_37660568 6.117 NM_003246
 THBS1
thrombospondin 1
chr4_+_184257337 5.285 NM_024949
 WWC2
WW and C2 domain containing 2
chr6_-_75972286 4.878 NM_004370
NM_080645
 COL12A1

collagen, type XII, alpha 1

chr10_-_125843092 4.519 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_-_39460687 4.481 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_-_1283770 4.148 NM_032348
 MXRA8
matrix-remodelling associated 8
chr15_+_73728402 3.950 NM_153271
 SNX33
sorting nexin 33
chr3_-_113841967 3.812 CCDC80
coiled-coil domain containing 80
chr14_-_88090641 3.721 NM_007039
 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_16355013 3.698 NM_004431
 EPHA2
EPH receptor A2
chr14_-_22516271 3.633 NM_198086
 JUB
jub, ajuba homolog (Xenopus laevis)
chr2_-_189752575 3.585 NM_000393
 COL5A2
collagen, type V, alpha 2
chr14_-_22515725 3.572 JUB
jub, ajuba homolog (Xenopus laevis)
chr11_-_6298284 3.496 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr1_+_85819004 3.461 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
3.07 2.65e-02 GO:0014706 striated muscle tissue development
2.52 2.01e-02 GO:0048514 blood vessel morphogenesis
2.37 1.61e-02 GO:0001568 blood vessel development
2.35 1.05e-02 GO:0001944 vasculature development
2.28 3.57e-02 GO:0061061 muscle structure development
2.25 3.46e-02 GO:0030029 actin filament-based process
2.21 3.85e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.03 8.62e-03 GO:0072358 cardiovascular system development
2.03 8.62e-03 GO:0072359 circulatory system development
1.97 6.53e-05 GO:0007155 cell adhesion
1.97 6.53e-05 GO:0022610 biological adhesion
1.77 1.63e-03 GO:0048468 cell development
1.55 5.61e-03 GO:0009653 anatomical structure morphogenesis
1.45 1.83e-02 GO:0048513 organ development
1.38 4.84e-03 GO:0048731 system development
1.35 5.65e-03 GO:0048856 anatomical structure development
1.34 2.79e-03 GO:0007275 multicellular organismal development
1.31 4.05e-03 GO:0032502 developmental process
1.24 1.20e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
12.70 3.45e-02 GO:0001527 microfibril
5.44 2.25e-02 GO:0001725 stress fiber
5.08 3.86e-02 GO:0032432 actin filament bundle
4.08 8.98e-04 GO:0005604 basement membrane
3.71 2.78e-05 GO:0044420 extracellular matrix part
2.45 2.17e-02 GO:0031252 cell leading edge
2.40 3.46e-04 GO:0015629 actin cytoskeleton
2.32 5.66e-05 GO:0031012 extracellular matrix
2.31 6.04e-04 GO:0005578 proteinaceous extracellular matrix
1.68 4.64e-04 GO:0044421 extracellular region part
1.54 5.52e-06 GO:0005576 extracellular region
1.46 1.27e-04 GO:0044459 plasma membrane part
1.31 1.02e-04 GO:0071944 cell periphery
1.30 3.04e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
7.62 3.50e-02 GO:0043236 laminin binding
6.10 1.39e-02 GO:0050840 extracellular matrix binding
4.43 3.05e-02 GO:0008307 structural constituent of muscle
3.81 1.70e-03 GO:0005201 extracellular matrix structural constituent
3.38 1.39e-03 GO:0019838 growth factor binding
2.89 3.74e-02 GO:0008201 heparin binding
2.83 4.87e-03 GO:0005539 glycosaminoglycan binding
2.74 5.42e-03 GO:0001871 pattern binding
2.74 5.42e-03 GO:0030247 polysaccharide binding
2.41 1.17e-04 GO:0003779 actin binding
1.88 5.68e-03 GO:0008092 cytoskeletal protein binding
1.76 9.92e-03 GO:0005509 calcium ion binding