Motif ID: ESR1.p2

Z-value: 1.658


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESR1chr6_+_1521703780.185.0e-01Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_24068759 2.433 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr19_+_15079141 2.255 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_36436316 2.013 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr16_+_54072969 1.712 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr22_+_36632242 1.682 NM_033386
MICALL1
MICAL-like 1
chr2_-_233501069 1.675 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr6_+_148705646 1.659 SASH1
SAM and SH3 domain containing 1
chr17_-_7238546 1.630 NM_020360
PLSCR3
phospholipid scramblase 3
chr6_+_148705421 1.434 NM_015278
SASH1
SAM and SH3 domain containing 1
chr1_+_15955719 1.337 FBLIM1
filamin binding LIM protein 1
chr16_-_1341766 1.307 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr9_+_136673464 1.303 NM_000093
COL5A1
collagen, type V, alpha 1
chr7_+_2638156 1.293 TTYH3
tweety homolog 3 (Drosophila)
chr10_+_115428924 1.278 NM_033340
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr7_+_99919485 1.267 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr9_-_139202855 1.264 NM_013366
ANAPC2
anaphase promoting complex subunit 2
chr19_+_47521600 1.219 NM_001410
MEGF8
multiple EGF-like-domains 8
chr19_-_60802663 1.215 NM_032836
FIZ1
FLT3-interacting zinc finger 1
chr17_-_3518568 1.208 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr22_-_18309312 1.208 TXNRD2
thioredoxin reductase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
5.68 4.78e-02 GO:0060411 cardiac septum morphogenesis
1.89 8.04e-03 GO:0001944 vasculature development
1.89 1.95e-02 GO:0001568 blood vessel development
1.71 3.68e-03 GO:0072358 cardiovascular system development
1.71 3.68e-03 GO:0072359 circulatory system development
1.47 2.11e-05 GO:0009966 regulation of signal transduction
1.41 1.71e-04 GO:0023051 regulation of signaling
1.34 3.23e-02 GO:0009653 anatomical structure morphogenesis
1.22 3.50e-03 GO:0023052 signaling
1.21 2.55e-02 GO:0007165 signal transduction
1.13 2.74e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.49 2.99e-02 GO:0030054 cell junction
1.10 2.29e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.69 3.72e-02 GO:0003779 actin binding
1.56 4.79e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.17 1.09e-06 GO:0005515 protein binding
1.07 7.77e-03 GO:0005488 binding