Motif ID: SP1.p2

Z-value: 1.224


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SP1chr12_+_520601910.048.7e-01Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_+_46226072 4.825 NM_001848
COL6A1
collagen, type VI, alpha 1
chr4_+_3264509 4.411 RGS12
regulator of G-protein signaling 12
chr7_+_5289079 4.319 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr13_-_113066366 3.776 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr2_+_42128521 3.489 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr2_+_235525355 3.337 NM_014521
SH3BP4
SH3-domain binding protein 4
chr17_-_829655 3.265 NM_022463
NXN
nucleoredoxin
chr19_+_59064795 3.250 MYADM
myeloid-associated differentiation marker
chr1_-_158335241 3.125 IGSF8
immunoglobulin superfamily, member 8
chr14_-_20636337 3.041 ZNF219
zinc finger protein 219
chr14_-_20636568 3.012 NM_016423
ZNF219
zinc finger protein 219
chr2_-_227372574 2.944 IRS1
insulin receptor substrate 1
chr19_+_59064471 2.906 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr15_+_78232194 2.868 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr1_-_158334983 2.756 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr15_+_97009194 2.702 IGF1R
insulin-like growth factor 1 receptor
chr3_-_125085834 2.679 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr7_+_55054152 2.536 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr18_+_11971421 2.474 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr15_+_71131877 2.470 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr16_-_2125825 2.469 NM_000296
NM_001009944
PKD1

polycystic kidney disease 1 (autosomal dominant)

chr17_-_63965156 2.444 NM_017983
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr2_-_219960725 2.442 DNPEP
aspartyl aminopeptidase
chr15_+_78232160 2.439 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr1_-_158334885 2.437 IGSF8
immunoglobulin superfamily, member 8
chr4_+_995609 2.433 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr9_+_123501186 2.384 DAB2IP
DAB2 interacting protein
chr22_+_49293520 2.379 NCAPH2
non-SMC condensin II complex, subunit H2
chr17_+_77582774 2.358 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr15_+_78232395 2.309 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr15_+_78232232 2.305 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr19_+_59062962 2.289 MYADM
myeloid-associated differentiation marker
chr17_-_78199384 2.270 NM_019613
WDR45L
WDR45-like
chr17_+_78630793 2.234 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr1_-_23683214 2.200 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr7_+_55054416 2.196 EGFR
epidermal growth factor receptor
chr18_+_11971443 2.196 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr2_-_220116508 2.182 NM_024536
CHPF
chondroitin polymerizing factor
chr1_+_9275518 2.172 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr12_-_123023052 2.166 NM_025140
CCDC92
coiled-coil domain containing 92
chr19_+_50041232 2.157 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr7_-_51351825 2.148 COBL
cordon-bleu homolog (mouse)
chr17_+_76623553 2.134 BAIAP2
BAI1-associated protein 2
chr9_-_129370954 2.122 FAM129B
family with sequence similarity 129, member B
chr11_+_65990869 2.103 NM_001098510
NM_145065
PELI3

pellino homolog 3 (Drosophila)

chr8_-_144722141 2.091 C8orf73
chromosome 8 open reading frame 73
chr2_-_219960813 2.083 DNPEP
aspartyl aminopeptidase
chr19_+_54786723 2.083 NM_020719
PRR12
proline rich 12
chr12_-_47468985 2.078 NM_020983
ADCY6
adenylate cyclase 6
chr20_+_32045214 2.061 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr20_-_62071584 2.048 NM_020713
ZNF512B
zinc finger protein 512B
chr16_-_960796 2.023 LMF1
lipase maturation factor 1
chr2_-_219960871 2.010 NM_012100
DNPEP
aspartyl aminopeptidase
chr19_+_59062982 2.010 MYADM
myeloid-associated differentiation marker
chr4_-_5941043 1.984 CRMP1
collapsin response mediator protein 1
chr20_+_32045087 1.975 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr7_+_36159300 1.968 NM_030636
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr3_-_52419086 1.956 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr20_+_32045386 1.931 NM_007367
NM_016732
RALY

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))

chr7_-_158073121 1.930 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr16_-_8870343 1.895 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr8_-_144995007 1.890 NM_178564
NRBP2
nuclear receptor binding protein 2
chr2_-_239987629 1.888 HDAC4
histone deacetylase 4
chr1_+_181259317 1.866


chr17_+_34114924 1.859 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr7_+_36159369 1.848 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr20_+_32045203 1.845 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr22_+_40107878 1.844 NM_003216
TEF
thyrotrophic embryonic factor
chr8_-_38444675 1.841 FGFR1
fibroblast growth factor receptor 1
chr1_+_31658549 1.838 NM_178865
SERINC2
serine incorporator 2
chr22_-_19122107 1.829 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr22_+_27798887 1.828 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr19_+_40213431 1.783 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr19_+_50041400 1.780 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr20_+_34357604 1.779 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr12_-_123023312 1.774 CCDC92
coiled-coil domain containing 92
chr20_-_17610704 1.768 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr1_-_23683308 1.763 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr4_+_996251 1.758 NM_021923
FGFRL1
fibroblast growth factor receptor-like 1
chr22_+_27609889 1.758 NM_032173
ZNRF3
zinc and ring finger 3
chr20_+_32045347 1.755 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr14_+_20608179 1.747 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr5_+_176446425 1.744 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr20_+_35407872 1.738 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr20_+_61996934 1.730 DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr18_+_11971552 1.720 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr20_+_34523231 1.713 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr4_+_3046034 1.709 NM_002111
HTT
huntingtin
chr20_+_32045319 1.704 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr3_-_187025501 1.701 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr6_-_44203131 1.676 MRPL14
mitochondrial ribosomal protein L14
chr22_-_19122047 1.672 SCARF2
scavenger receptor class F, member 2
chr18_-_28304392 1.667 NM_022751
FAM59A
family with sequence similarity 59, member A
chr19_-_50691999 1.651 NM_005619
NM_206900
RTN2

reticulon 2

chr17_-_77824529 1.646 CSNK1D
casein kinase 1, delta
chr17_-_77824560 1.631 CSNK1D
casein kinase 1, delta
chr17_+_56832255 1.623 TBX2
T-box 2
chr14_-_37134050 1.619 FOXA1
forkhead box A1
chr19_-_14062230 1.604 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr19_+_50041387 1.602 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr19_+_59062937 1.599 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr17_-_75624048 1.593 NM_019020
TBC1D16
TBC1 domain family, member 16
chr5_+_172193826 1.590 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr10_-_80875097 1.589 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr20_+_32928065 1.585 ACSS2
acyl-CoA synthetase short-chain family member 2
chr20_+_56900116 1.582 NM_001077488
GNAS
GNAS complex locus
chr3_+_185580554 1.581 NM_003741
CHRD
chordin
chr20_+_32927988 1.574 NM_001076552
NM_018677
ACSS2

acyl-CoA synthetase short-chain family member 2

chr6_+_44203335 1.572 NM_018426
TMEM63B
transmembrane protein 63B
chr12_+_3056781 1.572 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr13_+_97593469 1.567 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_960982 1.550 NM_022773
LMF1
lipase maturation factor 1
chr10_+_114699953 1.545 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr13_+_51056648 1.544 WDFY2
WD repeat and FYVE domain containing 2
chr5_+_92946348 1.540 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr17_+_78303202 1.536 NM_005993
TBCD
tubulin folding cofactor D
chr16_+_88467518 1.526 TCF25
transcription factor 25 (basic helix-loop-helix)
chrX_+_138060 1.523 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr14_-_20636909 1.521 NM_001101672
ZNF219
zinc finger protein 219
chr7_-_1465487 1.520 MICALL2
MICAL-like 2
chr10_-_35143900 1.518 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr19_+_3045528 1.516 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr2_+_24126140 1.506 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr8_+_144400480 1.504 NM_173832
ZFP41
zinc finger protein 41 homolog (mouse)
chr8_+_22513043 1.490 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr13_+_51056593 1.490 WDFY2
WD repeat and FYVE domain containing 2
chr9_+_139619969 1.489 ARRDC1
arrestin domain containing 1
chr14_+_104244998 1.485 INF2
inverted formin, FH2 and WH2 domain containing
chr1_-_22136263 1.482 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr19_+_38979502 1.481 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr1_+_9275542 1.474 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr12_+_130945215 1.470 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr9_-_130912603 1.459 CRAT
carnitine O-acetyltransferase
chr20_+_61996954 1.458 NM_025219
DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr6_+_37895570 1.458 ZFAND3
zinc finger, AN1-type domain 3
chr18_+_11971457 1.457 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr20_+_61841553 1.453 NM_020062
SLC2A4RG
SLC2A4 regulator
chr9_+_136358145 1.452 RXRA
retinoid X receptor, alpha
chr20_-_51644187 1.452 ZNF217
zinc finger protein 217
chr11_+_125730760 1.452 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr22_-_40315722 1.451 NM_002676
PMM1
phosphomannomutase 1
chr19_+_50041424 1.446 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr22_-_35113876 1.444 MYH9
myosin, heavy chain 9, non-muscle
chr15_-_27901628 1.441 TJP1
tight junction protein 1 (zona occludens 1)
chr17_-_76622967 1.441 FLJ90757
hypothetical LOC440465
chr2_-_64734294 1.436 SERTAD2
SERTA domain containing 2
chrX_+_153318452 1.431 NM_001493
GDI1
GDP dissociation inhibitor 1
chr10_+_134201262 1.428 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr15_+_71763742 1.426 CD276
CD276 molecule
chr9_+_115958051 1.424 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr2_+_28469199 1.419 FOSL2
FOS-like antigen 2
chr19_+_39664706 1.418 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr20_+_30410447 1.401 ASXL1
additional sex combs like 1 (Drosophila)
chr17_-_78249750 1.400 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chrX_-_106129854 1.396 MORC4
MORC family CW-type zinc finger 4
chr3_-_48445719 1.393 NM_002673
PLXNB1
plexin B1
chr19_-_17275083 1.391 NM_024527
ABHD8
abhydrolase domain containing 8
chr20_+_25176698 1.390 NM_002862
PYGB
phosphorylase, glycogen; brain
chr9_-_135923373 1.385 BRD3
bromodomain containing 3
chr15_+_78232184 1.380 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr17_+_56832492 1.380 TBX2
T-box 2
chr19_-_60827746 1.377 NM_203374
ZNF784
zinc finger protein 784
chr17_+_4657352 1.370 NM_002663
PLD2
phospholipase D2
chr5_-_1165106 1.370 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr5_-_2804768 1.370 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr19_+_47480445 1.369 NM_015125
CIC
capicua homolog (Drosophila)
chr3_+_37878647 1.368 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr17_-_60988077 1.367 NM_004655
AXIN2
axin 2
chr9_+_131974506 1.360 NM_014286
NCS1
neuronal calcium sensor 1
chr14_-_68515525 1.355 ACTN1
actinin, alpha 1
chr17_-_74432800 1.355 TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_945331 1.353 NM_198576
AGRN
agrin
chr4_-_2727816 1.353 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr22_-_35113947 1.352 MYH9
myosin, heavy chain 9, non-muscle
chr11_+_12652427 1.352 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr16_-_11257539 1.349 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr6_+_2945025 1.348 NM_000904
NQO2
NAD(P)H dehydrogenase, quinone 2
chr16_-_342399 1.348 NM_003502
NM_181050
AXIN1

axin 1

chr17_+_76623540 1.345 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr17_-_34157962 1.341 NM_007144
PCGF2
polycomb group ring finger 2
chr10_-_62431203 1.341 RHOBTB1
Rho-related BTB domain containing 1
chr21_+_42946719 1.336 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr20_-_60375695 1.336 NM_005560
LAMA5
laminin, alpha 5
chr16_+_88467493 1.335 NM_014972
TCF25
transcription factor 25 (basic helix-loop-helix)
chr5_+_167651063 1.331 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr15_+_71763773 1.331 CD276
CD276 molecule
chr10_-_134972540 1.328 NM_006659
TUBGCP2
tubulin, gamma complex associated protein 2
chrX_+_152643516 1.326 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr2_-_109728958 1.323 NM_144710
NM_178584
SEPT10

septin 10

chr17_+_4683280 1.316 NM_001024937
NM_015716
NM_153827
NM_170663
MINK1



misshapen-like kinase 1



chr21_+_46342440 1.315 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr19_+_18608827 1.313 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr17_-_3518568 1.313 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr3_-_187025438 1.302 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr20_+_4077409 1.294 NM_175839
NM_175840
NM_175841
NM_175842
SMOX



spermine oxidase



chr3_+_112273464 1.294 NM_015480
PVRL3
poliovirus receptor-related 3
chr17_+_78303317 1.293 TBCD
tubulin folding cofactor D
chr22_-_29052863 1.290 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr20_+_48240772 1.289 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr17_+_56831951 1.289 NM_005994
TBX2
T-box 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 4.09e-27 GO:0009987 cellular process
1.12 1.71e-21 GO:0044237 cellular metabolic process
1.14 1.99e-19 GO:0044260 cellular macromolecule metabolic process
1.09 1.10e-16 GO:0065007 biological regulation
1.10 9.07e-16 GO:0050794 regulation of cellular process
1.09 5.55e-15 GO:0008152 metabolic process
1.10 1.99e-14 GO:0044238 primary metabolic process
1.09 2.88e-14 GO:0050789 regulation of biological process
1.17 3.35e-13 GO:0044267 cellular protein metabolic process
1.11 3.59e-13 GO:0043170 macromolecule metabolic process
1.20 1.07e-12 GO:0006464 protein modification process
1.13 1.71e-10 GO:0031323 regulation of cellular metabolic process
1.18 2.50e-10 GO:0043412 macromolecule modification
1.13 3.97e-10 GO:0080090 regulation of primary metabolic process
1.12 5.23e-10 GO:0019222 regulation of metabolic process
1.17 9.87e-10 GO:0048523 negative regulation of cellular process
1.13 1.69e-09 GO:0016043 cellular component organization
1.12 3.45e-09 GO:0060255 regulation of macromolecule metabolic process
1.12 1.84e-08 GO:0071840 cellular component organization or biogenesis
1.17 1.18e-07 GO:0006996 organelle organization
1.14 2.28e-07 GO:0048519 negative regulation of biological process
1.12 5.88e-07 GO:0019538 protein metabolic process
1.13 7.68e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.13 8.52e-07 GO:0071842 cellular component organization at cellular level
1.21 9.31e-07 GO:0007049 cell cycle
1.13 1.93e-06 GO:0048522 positive regulation of cellular process
1.12 2.35e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.13 3.16e-06 GO:0010468 regulation of gene expression
1.12 5.56e-06 GO:0031326 regulation of cellular biosynthetic process
1.12 5.90e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.12 6.61e-06 GO:0048518 positive regulation of biological process
1.11 7.94e-06 GO:0034641 cellular nitrogen compound metabolic process
1.12 8.59e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.17 9.28e-06 GO:0009966 regulation of signal transduction
1.12 1.03e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.08e-05 GO:0031324 negative regulation of cellular metabolic process
1.21 1.22e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.18 1.88e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.12 1.90e-05 GO:0009889 regulation of biosynthetic process
1.10 1.92e-05 GO:0006807 nitrogen compound metabolic process
1.20 1.99e-05 GO:0032268 regulation of cellular protein metabolic process
1.12 2.11e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 2.14e-05 GO:0009892 negative regulation of metabolic process
1.19 2.33e-05 GO:0051246 regulation of protein metabolic process
1.21 4.74e-05 GO:0006351 transcription, DNA-dependent
1.12 5.58e-05 GO:0051252 regulation of RNA metabolic process
1.15 6.69e-05 GO:0023051 regulation of signaling
1.12 6.87e-05 GO:0044249 cellular biosynthetic process
1.17 7.86e-05 GO:0009893 positive regulation of metabolic process
1.12 8.77e-05 GO:0009058 biosynthetic process
1.14 9.57e-05 GO:0009059 macromolecule biosynthetic process
1.18 1.04e-04 GO:0044248 cellular catabolic process
1.24 1.04e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.17 1.26e-04 GO:0031325 positive regulation of cellular metabolic process
1.19 1.50e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 1.67e-04 GO:0022402 cell cycle process
1.31 1.76e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.30 2.17e-04 GO:0016568 chromatin modification
1.14 2.24e-04 GO:0034645 cellular macromolecule biosynthetic process
1.23 2.60e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.08 3.42e-04 GO:0051716 cellular response to stimulus
1.18 3.77e-04 GO:0032774 RNA biosynthetic process
1.09 4.14e-04 GO:0032502 developmental process
1.09 4.18e-04 GO:0007165 signal transduction
1.13 4.77e-04 GO:0016070 RNA metabolic process
1.09 5.27e-04 GO:0023052 signaling
1.35 9.00e-04 GO:0051248 negative regulation of protein metabolic process
1.12 9.14e-04 GO:0006355 regulation of transcription, DNA-dependent
1.24 9.98e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.19 1.02e-03 GO:0033554 cellular response to stress
1.11 1.06e-03 GO:0090304 nucleic acid metabolic process
1.23 1.08e-03 GO:0000278 mitotic cell cycle
1.21 1.09e-03 GO:0009890 negative regulation of biosynthetic process
1.21 1.14e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.14 1.19e-03 GO:0007399 nervous system development
1.24 1.19e-03 GO:0051253 negative regulation of RNA metabolic process
1.35 1.40e-03 GO:0046578 regulation of Ras protein signal transduction
1.14 1.42e-03 GO:0009056 catabolic process
1.22 1.64e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.15 1.72e-03 GO:0035556 intracellular signal transduction
1.19 1.77e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.22 1.86e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 2.11e-03 GO:0010629 negative regulation of gene expression
1.34 2.36e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.18 2.45e-03 GO:0008219 cell death
1.21 2.93e-03 GO:0051726 regulation of cell cycle
1.20 3.10e-03 GO:0022403 cell cycle phase
1.19 3.88e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 5.14e-03 GO:0007010 cytoskeleton organization
1.18 5.30e-03 GO:0016265 death
1.08 9.73e-03 GO:0007275 multicellular organismal development
1.20 1.03e-02 GO:0051254 positive regulation of RNA metabolic process
1.17 1.04e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.09 1.06e-02 GO:0048856 anatomical structure development
1.38 1.06e-02 GO:0051493 regulation of cytoskeleton organization
1.16 1.15e-02 GO:0006793 phosphorus metabolic process
1.16 1.15e-02 GO:0006796 phosphate metabolic process
1.33 1.21e-02 GO:0051129 negative regulation of cellular component organization
1.38 1.33e-02 GO:0006417 regulation of translation
1.20 1.42e-02 GO:0009057 macromolecule catabolic process
1.28 1.46e-02 GO:0033043 regulation of organelle organization
1.17 1.60e-02 GO:0051128 regulation of cellular component organization
1.28 1.60e-02 GO:0048285 organelle fission
1.14 2.23e-02 GO:0051641 cellular localization
1.18 2.30e-02 GO:0006915 apoptosis
1.11 2.44e-02 GO:0048583 regulation of response to stimulus
1.21 2.46e-02 GO:0044265 cellular macromolecule catabolic process
1.18 2.50e-02 GO:0012501 programmed cell death
1.17 2.67e-02 GO:0046907 intracellular transport
1.27 2.68e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.16 3.85e-02 GO:0009891 positive regulation of biosynthetic process
1.08 4.94e-02 GO:0051234 establishment of localization
1.08 4.95e-02 GO:0048731 system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 3.51e-55 GO:0005622 intracellular
1.10 2.16e-53 GO:0044424 intracellular part
1.10 2.85e-35 GO:0043226 organelle
1.10 7.41e-35 GO:0043229 intracellular organelle
1.11 1.32e-34 GO:0005737 cytoplasm
1.10 2.65e-33 GO:0043227 membrane-bounded organelle
1.10 1.60e-32 GO:0043231 intracellular membrane-bounded organelle
1.13 8.42e-24 GO:0005634 nucleus
1.11 1.58e-18 GO:0044444 cytoplasmic part
1.11 1.30e-16 GO:0044446 intracellular organelle part
1.11 3.35e-16 GO:0044422 organelle part
1.20 1.60e-15 GO:0005829 cytosol
1.17 1.31e-12 GO:0044428 nuclear part
1.03 5.85e-11 GO:0005623 cell
1.03 7.05e-11 GO:0044464 cell part
1.18 8.77e-11 GO:0031981 nuclear lumen
1.15 1.69e-09 GO:0070013 intracellular organelle lumen
1.20 3.78e-09 GO:0005654 nucleoplasm
1.15 5.23e-09 GO:0043233 organelle lumen
1.14 1.29e-08 GO:0031974 membrane-enclosed lumen
1.12 1.21e-07 GO:0043234 protein complex
1.25 1.80e-07 GO:0015630 microtubule cytoskeleton
1.23 1.99e-06 GO:0044451 nucleoplasm part
1.19 1.88e-05 GO:0005794 Golgi apparatus
1.10 3.69e-05 GO:0043228 non-membrane-bounded organelle
1.10 3.69e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.09 4.84e-05 GO:0032991 macromolecular complex
1.13 3.42e-04 GO:0005856 cytoskeleton
1.37 9.93e-04 GO:0005819 spindle
1.17 1.18e-03 GO:0042995 cell projection
1.27 1.35e-03 GO:0005815 microtubule organizing center
1.12 1.66e-03 GO:0012505 endomembrane system
1.21 2.24e-03 GO:0005694 chromosome
1.10 3.46e-03 GO:0031090 organelle membrane
1.35 3.90e-03 GO:0031252 cell leading edge
1.14 4.91e-03 GO:0044430 cytoskeletal part
1.48 6.70e-03 GO:0016585 chromatin remodeling complex
1.27 7.25e-03 GO:0005874 microtubule
1.37 8.26e-03 GO:0005912 adherens junction
1.19 1.23e-02 GO:0044431 Golgi apparatus part
1.22 1.71e-02 GO:0043005 neuron projection
1.29 3.15e-02 GO:0000228 nuclear chromosome
1.33 3.41e-02 GO:0070161 anchoring junction
1.19 4.95e-02 GO:0000139 Golgi membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 2.16e-30 GO:0005515 protein binding
1.07 5.56e-28 GO:0005488 binding
1.29 3.59e-07 GO:0008092 cytoskeletal protein binding
1.13 1.49e-06 GO:0000166 nucleotide binding
1.10 2.81e-06 GO:0003676 nucleic acid binding
1.12 1.08e-05 GO:0003677 DNA binding
1.22 1.51e-05 GO:0019899 enzyme binding
1.07 2.58e-05 GO:0003824 catalytic activity
1.19 3.38e-05 GO:0001071 nucleic acid binding transcription factor activity
1.19 3.38e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 3.93e-05 GO:0030528 transcription regulator activity
1.27 8.63e-05 GO:0019904 protein domain specific binding
1.13 1.33e-04 GO:0016740 transferase activity
1.12 2.79e-04 GO:0017076 purine nucleotide binding
1.12 6.02e-04 GO:0032553 ribonucleotide binding
1.12 6.02e-04 GO:0032555 purine ribonucleotide binding
1.12 1.10e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.25 1.33e-03 GO:0004674 protein serine/threonine kinase activity
1.13 1.87e-03 GO:0030554 adenyl nucleotide binding
1.46 2.48e-03 GO:0015631 tubulin binding
1.18 2.78e-03 GO:0016301 kinase activity
1.12 4.09e-03 GO:0032559 adenyl ribonucleotide binding
1.12 5.11e-03 GO:0005524 ATP binding
1.17 8.06e-03 GO:0042802 identical protein binding
1.17 1.64e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.15 2.17e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.18 4.33e-02 GO:0004672 protein kinase activity
1.24 4.81e-02 GO:0003779 actin binding