Motif ID: RUNX1..3.p2

Z-value: 1.697


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX3chr1_-_251640610.775.5e-04Click!
RUNX1chr21_-_353434280.505.1e-02Click!
RUNX2chr6_+_45498354-0.146.0e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_114215768 3.879 NM_001193431
NM_012411
NM_015967
 PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr16_+_23754772 3.525 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr8_-_102872354 3.324 NCALD
neurocalcin delta
chr1_-_25164061 3.202 NM_001031680
 RUNX3
runt-related transcription factor 3
chr2_-_158008763 2.987 NM_004288
 CYTIP
cytohesin 1 interacting protein
chr16_+_29582069 2.907 NM_003123
 SPN
sialophorin
chr17_-_31441390 2.456 NM_002983
 CCL3
chemokine (C-C motif) ligand 3
chrX_-_30505804 2.421 NM_025159
 CXorf21
chromosome X open reading frame 21
chr16_+_29582065 2.329 SPN
sialophorin
chr8_-_21827057 2.254 NM_003974
 DOK2
docking protein 2, 56kDa
chr22_+_21318779 2.234 NM_199127
 GGTLC2
gamma-glutamyltransferase light chain 2
chr9_-_129580732 2.187 NM_170600
 SH2D3C
SH2 domain containing 3C
chr8_-_102872614 2.058 NM_032041
 NCALD
neurocalcin delta
chr16_+_23754822 2.053 PRKCB
protein kinase C, beta
chr22_+_38627031 1.905 NM_004810
 GRAP2
GRB2-related adaptor protein 2
chrX_-_131089552 1.884 NM_194277
 FRMD7
FERM domain containing 7
chr7_+_142850667 1.791 NM_177437
 TAS2R60
taste receptor, type 2, member 60
chr6_-_41276901 1.762 NM_024807
 TREML2
triggering receptor expressed on myeloid cells-like 2
chrX_+_78087484 1.715 NM_014499
NM_198333
 P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr1_+_32489426 1.667 NM_005356
 LCK
lymphocyte-specific protein tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.62 7.97e-15 GO:0007608 sensory perception of smell
2.45 1.91e-13 GO:0007606 sensory perception of chemical stimulus
2.23 7.51e-03 GO:0046649 lymphocyte activation
1.91 6.92e-10 GO:0007600 sensory perception
1.76 4.26e-03 GO:0001775 cell activation
1.73 3.02e-05 GO:0006955 immune response
1.63 2.60e-07 GO:0002376 immune system process
1.62 7.29e-08 GO:0050877 neurological system process
1.60 8.08e-10 GO:0003008 system process
1.36 6.76e-03 GO:0007166 cell surface receptor linked signaling pathway
1.27 2.77e-11 GO:0050896 response to stimulus
1.27 2.66e-08 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.50 5.45e-04 GO:0009897 external side of plasma membrane
1.59 2.08e-07 GO:0005887 integral to plasma membrane
1.58 2.73e-07 GO:0031226 intrinsic to plasma membrane
1.51 6.18e-03 GO:0005615 extracellular space
1.42 1.42e-16 GO:0005886 plasma membrane
1.42 4.18e-07 GO:0044459 plasma membrane part
1.41 2.02e-16 GO:0071944 cell periphery
1.31 2.04e-03 GO:0005576 extracellular region
1.29 5.20e-12 GO:0031224 intrinsic to membrane
1.29 3.72e-11 GO:0016021 integral to membrane
1.25 8.12e-11 GO:0044425 membrane part
1.16 6.84e-06 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
5.01 1.40e-06 GO:0003823 antigen binding
2.63 8.64e-15 GO:0004984 olfactory receptor activity
2.07 1.01e-02 GO:0005125 cytokine activity
2.01 1.40e-13 GO:0004930 G-protein coupled receptor activity
1.91 1.02e-17 GO:0004888 transmembrane receptor activity
1.84 2.41e-21 GO:0004872 receptor activity
1.71 1.25e-19 GO:0004871 signal transducer activity
1.71 1.25e-19 GO:0060089 molecular transducer activity