Motif ID: KLF4.p3

Z-value: 1.581


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_1092901070.448.5e-02Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_61742111 2.042 NM_020828
 ZFP28
zinc finger protein 28 homolog (mouse)
chr19_-_50691999 1.936 NM_005619
NM_206900
 RTN2

reticulon 2

chr17_+_45488330 1.824 NM_002204
NM_005501
 ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr11_-_94603857 1.730 NM_144665
 SESN3
sestrin 3
chr11_+_65990869 1.640 NM_001098510
NM_145065
 PELI3

pellino homolog 3 (Drosophila)

chr19_+_5855842 1.600 NM_001017921
 VMAC
vimentin-type intermediate filament associated coiled-coil protein
chrX_-_149817785 1.565 NM_001184808
NM_031462
NM_134445
NM_134446
 CD99L2



CD99 molecule-like 2



chr2_-_37752272 1.515 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_+_45488356 1.490 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_-_54835162 1.386 NM_006270
 RRAS
related RAS viral (r-ras) oncogene homolog
chr3_+_137167296 1.385 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chrX_-_135161185 1.371 NM_001173517
NM_024597
 MAP7D3

MAP7 domain containing 3

chr19_+_45976001 1.358 NM_016154
 RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 read-through transcript
RAB4B, member RAS oncogene family
chr11_-_65443015 1.347 NM_001135635
NM_031450
 C11orf68

chromosome 11 open reading frame 68

chr19_-_45888259 1.312 NM_004756
 NUMBL
numb homolog (Drosophila)-like
chr2_-_235070431 1.250 NM_005737
 ARL4C
ADP-ribosylation factor-like 4C
chr11_+_65443303 1.225 NM_006442
 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_-_2804768 1.203 NM_001134222
NM_033267
 IRX2

iroquois homeobox 2

chr14_+_95928189 1.193 NM_152327
 AK7
adenylate kinase 7
chr8_-_144887876 1.183 NM_198488
 FAM83H
family with sequence similarity 83, member H

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
1.49 9.54e-03 GO:0051789 response to protein stimulus
1.31 2.97e-02 GO:0051329 interphase of mitotic cell cycle
1.30 3.84e-02 GO:0051325 interphase
1.30 3.90e-02 GO:0048285 organelle fission
1.25 2.83e-03 GO:0000278 mitotic cell cycle
1.22 3.38e-03 GO:0006915 apoptosis
1.22 4.56e-03 GO:0012501 programmed cell death
1.22 2.07e-02 GO:0005975 carbohydrate metabolic process
1.21 1.70e-02 GO:0022403 cell cycle phase
1.20 2.02e-04 GO:0008104 protein localization
1.20 1.81e-03 GO:0008219 cell death
1.20 3.66e-03 GO:0016265 death
1.19 1.12e-07 GO:0006996 organelle organization
1.19 9.97e-06 GO:0033036 macromolecule localization
1.19 1.08e-02 GO:0045184 establishment of protein localization
1.19 3.25e-02 GO:0022402 cell cycle process
1.18 3.91e-07 GO:0006464 protein modification process
1.18 3.53e-02 GO:0015031 protein transport
1.17 1.68e-02 GO:0007049 cell cycle
1.15 1.37e-08 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
1.56 4.80e-02 GO:0000922 spindle pole
1.55 1.47e-03 GO:0005925 focal adhesion
1.51 3.41e-03 GO:0030055 cell-substrate junction
1.50 7.38e-03 GO:0005924 cell-substrate adherens junction
1.50 2.86e-02 GO:0016585 chromatin remodeling complex
1.44 2.65e-03 GO:0005912 adherens junction
1.39 6.89e-03 GO:0070161 anchoring junction
1.38 7.70e-03 GO:0031252 cell leading edge
1.36 1.51e-02 GO:0005819 spindle
1.31 3.36e-03 GO:0015629 actin cytoskeleton
1.27 4.66e-02 GO:0005874 microtubule
1.26 6.65e-06 GO:0015630 microtubule cytoskeleton
1.26 2.12e-02 GO:0005815 microtubule organizing center
1.25 2.42e-03 GO:0000139 Golgi membrane
1.23 5.83e-04 GO:0030054 cell junction
1.23 1.56e-02 GO:0044427 chromosomal part
1.21 1.71e-06 GO:0044430 cytoskeletal part
1.20 2.35e-02 GO:0044431 Golgi apparatus part
1.19 2.63e-11 GO:0005829 cytosol
1.19 1.19e-04 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.32 2.91e-02 GO:0070412 R-SMAD binding
1.34 1.31e-02 GO:0003713 transcription coactivator activity
1.32 1.43e-04 GO:0000988 protein binding transcription factor activity
1.32 1.43e-04 GO:0000989 transcription factor binding transcription factor activity
1.31 1.90e-04 GO:0003712 transcription cofactor activity
1.26 2.53e-03 GO:0019904 protein domain specific binding
1.26 1.75e-02 GO:0005525 GTP binding
1.23 6.82e-03 GO:0008092 cytoskeletal protein binding
1.20 2.16e-03 GO:0019899 enzyme binding
1.14 5.72e-33 GO:0005515 protein binding
1.14 3.07e-06 GO:0000166 nucleotide binding
1.14 4.61e-05 GO:0017076 purine nucleotide binding
1.14 4.82e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.14 5.20e-05 GO:0032553 ribonucleotide binding
1.14 5.20e-05 GO:0032555 purine ribonucleotide binding
1.06 2.02e-21 GO:0005488 binding
1.06 1.14e-02 GO:0003824 catalytic activity