Motif ID: KLF4.p3

Z-value: 1.581


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_1092901070.448.5e-02Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_61742111 2.042 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr19_-_50691999 1.936 NM_005619
NM_206900
RTN2

reticulon 2

chr17_+_45488330 1.824 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr11_-_94603857 1.730 NM_144665
SESN3
sestrin 3
chr11_+_65990869 1.640 NM_001098510
NM_145065
PELI3

pellino homolog 3 (Drosophila)

chr19_+_5855842 1.600 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chrX_-_149817785 1.565 NM_001184808
NM_031462
NM_134445
NM_134446
CD99L2



CD99 molecule-like 2



chr2_-_37752272 1.515 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_+_45488356 1.490 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_-_54835162 1.386 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr3_+_137167296 1.385 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chrX_-_135161185 1.371 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr19_+_45976001 1.358 NM_016154
RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 read-through transcript
RAB4B, member RAS oncogene family
chr11_-_65443015 1.347 NM_001135635
NM_031450
C11orf68

chromosome 11 open reading frame 68

chr19_-_45888259 1.312 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr2_-_235070431 1.250 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr11_+_65443303 1.225 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_-_2804768 1.203 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr14_+_95928189 1.193 NM_152327
AK7
adenylate kinase 7
chr8_-_144887876 1.183 NM_198488
FAM83H
family with sequence similarity 83, member H
chr15_+_61356801 1.170 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr2_-_37752731 1.152 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr15_-_70399301 1.150 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr20_-_56317894 1.137 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr10_+_11824361 1.110 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr12_+_48303607 1.106 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_12747263 1.099 HOOK2
hook homolog 2 (Drosophila)
chr13_+_41520888 1.082 NM_152910
NM_178009
DGKH

diacylglycerol kinase, eta

chr13_-_109236897 1.056 NM_003749
IRS2
insulin receptor substrate 2
chrX_+_64804235 1.054 NM_002444
MSN
moesin
chr10_-_134940315 1.052 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr19_-_15204767 1.048 NM_001142886
EPHX3
epoxide hydrolase 3
chr6_-_31805547 1.047 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_+_10574055 1.046 NM_001145056
SLC44A2
solute carrier family 44, member 2
chrX_+_64804259 1.041 MSN
moesin
chr5_-_16989290 1.039 MYO10
myosin X
chr22_-_29015452 1.019 NM_001037666
GATSL3
GATS protein-like 3
chr1_-_113059396 1.011 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chrX_+_64804318 1.005 MSN
moesin
chr6_-_29708647 1.004 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_32992131 1.004


chr8_-_22044463 0.991 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr19_-_6718417 0.967 NM_005490
SH2D3A
SH2 domain containing 3A
chr22_-_29052863 0.953 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr12_+_56406296 0.943 LOC100130776
hypothetical LOC100130776
chr19_+_60487345 0.933 NM_032430
BRSK1
BR serine/threonine kinase 1
chr12_-_53099203 0.933 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_45759691 0.932 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr10_-_105604942 0.931 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr22_-_49050847 0.927 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr12_-_53099277 0.923 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_6243621 0.923 NM_207370
GPR153
G protein-coupled receptor 153
chr19_-_19599973 0.912 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr3_+_185762233 0.911 NM_004443
EPHB3
EPH receptor B3
chr11_-_62146144 0.910 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_18608827 0.909 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr11_-_11987115 0.908 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr14_-_104515738 0.900 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chrX_-_149817720 0.898 CD99L2
CD99 molecule-like 2
chr19_-_48976852 0.897 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr8_-_144722141 0.886 C8orf73
chromosome 8 open reading frame 73
chrX_+_152891184 0.885 NM_003492
TMEM187
transmembrane protein 187
chr9_-_100057313 0.884 TBC1D2
TBC1 domain family, member 2
chr12_-_53099269 0.883 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_51900388 0.876 NM_001042728
RARG
retinoic acid receptor, gamma
chr11_-_127897271 0.871 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr5_+_176006993 0.867 NM_001006616
NM_012171
NM_130465
TSPAN17


tetraspanin 17


chr1_+_156229686 0.864 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr9_+_129962292 0.863 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr7_+_100584397 0.857 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_-_46855116 0.857 NM_201403
MOBKL2C
MOB1, Mps One Binder kinase activator-like 2C (yeast)
chr8_+_32525269 0.856 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr9_+_139006663 0.854 NM_183241
C9orf142
chromosome 9 open reading frame 142
chrX_-_134060329 0.846 NCRNA00087
non-protein coding RNA 87
chr5_+_176007095 0.840 TSPAN17
tetraspanin 17
chr2_+_84986273 0.838 NM_021103
TMSB10
thymosin beta 10
chr5_+_176492662 0.837 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr9_-_109291575 0.835 KLF4
Kruppel-like factor 4 (gut)
chr1_+_231530136 0.823 NM_032435
KIAA1804
mixed lineage kinase 4
chrX_-_152642716 0.820 NM_001139457
NM_001139441
BCAP31

B-cell receptor-associated protein 31

chr22_+_41877502 0.815 TSPO
translocator protein (18kDa)
chr11_+_63829616 0.814 NM_004451
ESRRA
estrogen-related receptor alpha
chr11_+_65443452 0.804 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_48977247 0.804 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chrX_+_153318452 0.799 NM_001493
GDI1
GDP dissociation inhibitor 1
chr9_-_129371171 0.793 NM_022833
FAM129B
family with sequence similarity 129, member B
chr5_+_176786279 0.790 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr19_+_50535837 0.789 NM_177417
KLC3
kinesin light chain 3
chr19_+_60283571 0.788 NM_017729
EPS8L1
EPS8-like 1
chr2_+_241023908 0.786 GPC1
glypican 1
chr14_-_104705753 0.781 JAG2
jagged 2
chr19_+_40298571 0.776 NM_001136007
NM_001136008
NM_001136009
NM_001136010
NM_001136011
NM_001136012
NM_005971
NM_021910
FXYD3







FXYD domain containing ion transport regulator 3







chr17_-_78249750 0.775 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr3_-_52418933 0.774 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr7_+_73136085 0.771 NM_002314
LIMK1
LIM domain kinase 1
chr19_+_50196526 0.769 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr11_+_65443484 0.766 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_2672337 0.766 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr19_-_18493886 0.765 NM_006532
ELL
elongation factor RNA polymerase II
chr19_+_45811316 0.762 LTBP4
latent transforming growth factor beta binding protein 4
chr11_-_525532 0.760 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr19_-_18493847 0.751 ELL
elongation factor RNA polymerase II
chr18_-_50004770 0.747 MBD2
methyl-CpG binding domain protein 2
chrX_-_152643001 0.744


chr1_+_110554836 0.732 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr9_-_138560058 0.730 NM_017617
NOTCH1
notch 1
chr6_-_42527760 0.727 NM_033502
TRERF1
transcriptional regulating factor 1
chr14_+_104244998 0.727 INF2
inverted formin, FH2 and WH2 domain containing
chr19_-_45663463 0.723 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chrX_-_152517629 0.723 FAM58A
family with sequence similarity 58, member A
chr7_+_100302885 0.722 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr9_-_129370954 0.718 FAM129B
family with sequence similarity 129, member B
chr12_-_46585032 0.716 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chrX_-_152643042 0.710 BCAP31
B-cell receptor-associated protein 31
chr3_+_128874458 0.696 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr3_-_46710137 0.694 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr1_+_182622987 0.692 C1orf21
chromosome 1 open reading frame 21
chr17_+_39990124 0.691 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr1_-_32940850 0.688 SYNC
syncoilin, intermediate filament protein
chr10_-_3204955 0.685 PITRM1
pitrilysin metallopeptidase 1
chr1_-_29321599 0.684 NM_001171868
TMEM200B
transmembrane protein 200B
chr11_-_56848859 0.683 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_-_11987458 0.679 NM_013253
DKK3
dickkopf homolog 3 (Xenopus laevis)
chrX_-_152643016 0.676 NM_005745
BCAP31
B-cell receptor-associated protein 31
chr11_+_76249550 0.675 NM_018367
ACER3
alkaline ceramidase 3
chr7_+_115926855 0.674 CAV2
caveolin 2
chr11_-_11987414 0.673 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr18_-_50004932 0.673 MBD2
methyl-CpG binding domain protein 2
chr8_+_144888275 0.669 LOC100128338
hypothetical LOC100128338
chr4_+_87734489 0.668 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr9_+_139619918 0.668 ARRDC1
arrestin domain containing 1
chr18_+_32131628 0.667 NM_025135
FHOD3
formin homology 2 domain containing 3
chr1_+_149750485 0.667 NM_020770
CGN
cingulin
chrX_-_152517815 0.667 NM_001130997
NM_152274
FAM58A

family with sequence similarity 58, member A

chr1_-_27211913 0.665 NM_052943
FAM46B
family with sequence similarity 46, member B
chr5_+_10617431 0.664 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr12_-_47868563 0.662 TUBA1A
tubulin, alpha 1a
chr17_-_7323528 0.658 ZBTB4
zinc finger and BTB domain containing 4
chr22_-_17489718 0.657 DGCR2
DiGeorge syndrome critical region gene 2
chr12_+_115455579 0.654 NCRNA00173
non-protein coding RNA 173
chr21_+_34367747 0.653 MRPS6
mitochondrial ribosomal protein S6
chr7_-_72791090 0.651 NM_001145364
NM_148912
NM_148913
ABHD11


abhydrolase domain containing 11


chr11_-_11987198 0.651 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr9_+_35819375 0.651 NM_001042590
TMEM8B
transmembrane protein 8B
chr19_+_7801110 0.651 NM_145245
EVI5L
ecotropic viral integration site 5-like
chr3_-_52419056 0.651 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr15_+_39907447 0.649 NM_001114632
NM_001198588
NM_005090
JMJD7
JMJD7-PLA2G4B

jumonji domain containing 7
JMJD7-PLA2G4B readthrough

chr11_-_66877519 0.647 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr10_+_112247614 0.637 NM_004419
DUSP5
dual specificity phosphatase 5
chr2_+_241023703 0.633 NM_002081
GPC1
glypican 1
chr11_+_56984702 0.632 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr9_-_35101534 0.630 KIAA1539
KIAA1539
chr4_+_79691875 0.627 ANXA3
annexin A3
chr22_+_36632242 0.626 NM_033386
MICALL1
MICAL-like 1
chr18_+_11971457 0.622 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr8_-_145088679 0.621 NM_201383
PLEC
plectin
chr9_-_130830255 0.620 NM_020145
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr17_-_73867748 0.619 NM_003955
SOCS3
suppressor of cytokine signaling 3
chrX_+_117513899 0.617 NM_144658
DOCK11
dedicator of cytokinesis 11
chr3_-_52065130 0.617 NM_001947
DUSP7
dual specificity phosphatase 7
chr9_+_139619969 0.614 ARRDC1
arrestin domain containing 1
chr11_+_64838882 0.612 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr22_-_37878394 0.611 NM_175709
CBX7
chromobox homolog 7
chr1_-_208046011 0.608 NM_006147
IRF6
interferon regulatory factor 6
chr8_+_144870482 0.606 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr12_+_12935619 0.603 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_+_138497767 0.602 NM_152571
C9orf163
chromosome 9 open reading frame 163
chrX_+_17303458 0.599 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_11788550 0.599 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_48607596 0.598 NM_000094
COL7A1
collagen, type VII, alpha 1
chr17_-_40674883 0.597


chr8_-_145122884 0.596 NM_000445
PLEC
plectin
chr21_+_46568460 0.595 NM_006031
PCNT
pericentrin
chr8_-_127639647 0.591 FAM84B
family with sequence similarity 84, member B
chr12_-_48508411 0.590 NM_001037806
NCKAP5L
NCK-associated protein 5-like
chr19_+_53819460 0.589 SPHK2
sphingosine kinase 2
chr1_-_33420213 0.585 NM_018207
TRIM62
tripartite motif containing 62
chrX_+_48915127 0.584 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr7_-_87687302 0.581 NM_003130
SRI
sorcin
chr11_-_62145952 0.579 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_54558798 0.578 NM_001197302
NM_001197301
NM_014419
DKKL1


dickkopf-like 1


chr2_-_1727292 0.577 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr10_-_116154504 0.576 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr12_+_56202874 0.576 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr13_+_72531098 0.575 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr19_-_10807866 0.575 NM_006858
TMED1
transmembrane emp24 protein transport domain containing 1
chr8_+_22513043 0.574 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr6_-_31805932 0.574 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr9_+_35819208 0.573 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr18_+_54682261 0.570 ZNF532
zinc finger protein 532
chr19_+_60487578 0.570 BRSK1
BR serine/threonine kinase 1
chr5_-_176857158 0.569 PDLIM7
PDZ and LIM domain 7 (enigma)
chr9_-_35101592 0.568 KIAA1539
KIAA1539
chr11_-_125730655 0.566 FLJ39051
hypothetical LOC399972
chr1_+_35031185 0.566 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr22_-_17546296 0.566 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr4_+_154606900 0.565 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr2_-_120697148 0.565 TMEM185B
transmembrane protein 185B (pseudogene)
chr3_+_38182251 0.565 OXSR1
oxidative-stress responsive 1
chr22_+_41877470 0.564 NM_000714
NM_007311
TSPO

translocator protein (18kDa)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 3.29e-17 GO:0009987 cellular process
1.10 1.01e-10 GO:0044237 cellular metabolic process
1.09 6.92e-09 GO:0044238 primary metabolic process
1.13 1.04e-08 GO:0016043 cellular component organization
1.15 1.37e-08 GO:0071842 cellular component organization at cellular level
1.11 9.82e-08 GO:0044260 cellular macromolecule metabolic process
1.19 1.12e-07 GO:0006996 organelle organization
1.12 1.31e-07 GO:0071840 cellular component organization or biogenesis
1.14 1.45e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.08 1.48e-07 GO:0008152 metabolic process
1.18 3.91e-07 GO:0006464 protein modification process
1.07 2.36e-06 GO:0050794 regulation of cellular process
1.07 3.01e-06 GO:0050789 regulation of biological process
1.19 9.97e-06 GO:0033036 macromolecule localization
1.06 1.06e-05 GO:0065007 biological regulation
1.09 1.42e-05 GO:0043170 macromolecule metabolic process
1.13 2.57e-05 GO:0044267 cellular protein metabolic process
1.15 3.47e-05 GO:0043412 macromolecule modification
1.12 5.72e-05 GO:0051234 establishment of localization
1.11 1.70e-04 GO:0006810 transport
1.20 2.02e-04 GO:0008104 protein localization
1.10 8.71e-04 GO:0051179 localization
1.11 1.17e-03 GO:0019538 protein metabolic process
1.20 1.81e-03 GO:0008219 cell death
1.25 2.83e-03 GO:0000278 mitotic cell cycle
1.22 3.38e-03 GO:0006915 apoptosis
1.20 3.66e-03 GO:0016265 death
1.22 4.56e-03 GO:0012501 programmed cell death
1.12 9.41e-03 GO:0048523 negative regulation of cellular process
1.49 9.54e-03 GO:0051789 response to protein stimulus
1.15 1.04e-02 GO:0035556 intracellular signal transduction
1.19 1.08e-02 GO:0045184 establishment of protein localization
1.11 1.44e-02 GO:0048519 negative regulation of biological process
1.17 1.68e-02 GO:0007049 cell cycle
1.21 1.70e-02 GO:0022403 cell cycle phase
1.09 1.81e-02 GO:0006807 nitrogen compound metabolic process
1.22 2.07e-02 GO:0005975 carbohydrate metabolic process
1.09 2.31e-02 GO:0007165 signal transduction
1.14 2.69e-02 GO:0009966 regulation of signal transduction
1.31 2.97e-02 GO:0051329 interphase of mitotic cell cycle
1.08 2.98e-02 GO:0023052 signaling
1.19 3.25e-02 GO:0022402 cell cycle process
1.13 3.29e-02 GO:0023051 regulation of signaling
1.18 3.53e-02 GO:0015031 protein transport
1.09 3.78e-02 GO:0034641 cellular nitrogen compound metabolic process
1.30 3.84e-02 GO:0051325 interphase
1.30 3.90e-02 GO:0048285 organelle fission

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 1.74e-33 GO:0005622 intracellular
1.08 1.43e-31 GO:0044424 intracellular part
1.11 1.35e-27 GO:0005737 cytoplasm
1.09 7.56e-26 GO:0043229 intracellular organelle
1.09 1.01e-25 GO:0043226 organelle
1.09 7.63e-21 GO:0043231 intracellular membrane-bounded organelle
1.09 1.00e-20 GO:0043227 membrane-bounded organelle
1.13 1.23e-20 GO:0044444 cytoplasmic part
1.12 5.66e-15 GO:0044446 intracellular organelle part
1.11 1.10e-14 GO:0044422 organelle part
1.10 8.28e-12 GO:0005634 nucleus
1.19 2.63e-11 GO:0005829 cytosol
1.18 2.05e-07 GO:0005856 cytoskeleton
1.12 8.77e-07 GO:0043234 protein complex
1.21 1.71e-06 GO:0044430 cytoskeletal part
1.26 6.65e-06 GO:0015630 microtubule cytoskeleton
1.16 8.21e-06 GO:0012505 endomembrane system
1.12 1.29e-05 GO:0043228 non-membrane-bounded organelle
1.12 1.29e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.02 3.24e-05 GO:0044464 cell part
1.02 3.60e-05 GO:0005623 cell
1.13 4.18e-05 GO:0070013 intracellular organelle lumen
1.17 4.71e-05 GO:0005654 nucleoplasm
1.13 4.71e-05 GO:0044428 nuclear part
1.19 1.19e-04 GO:0005794 Golgi apparatus
1.14 1.44e-04 GO:0031981 nuclear lumen
1.12 1.90e-04 GO:0043233 organelle lumen
1.12 2.32e-04 GO:0031974 membrane-enclosed lumen
1.09 3.46e-04 GO:0032991 macromolecular complex
1.23 5.83e-04 GO:0030054 cell junction
1.55 1.47e-03 GO:0005925 focal adhesion
1.25 2.42e-03 GO:0000139 Golgi membrane
1.44 2.65e-03 GO:0005912 adherens junction
1.11 2.83e-03 GO:0031090 organelle membrane
1.31 3.36e-03 GO:0015629 actin cytoskeleton
1.51 3.41e-03 GO:0030055 cell-substrate junction
1.39 6.89e-03 GO:0070161 anchoring junction
1.50 7.38e-03 GO:0005924 cell-substrate adherens junction
1.38 7.70e-03 GO:0031252 cell leading edge
1.36 1.51e-02 GO:0005819 spindle
1.23 1.56e-02 GO:0044427 chromosomal part
1.26 2.12e-02 GO:0005815 microtubule organizing center
1.20 2.35e-02 GO:0044431 Golgi apparatus part
1.50 2.86e-02 GO:0016585 chromatin remodeling complex
1.27 4.66e-02 GO:0005874 microtubule
1.56 4.80e-02 GO:0000922 spindle pole

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 5.72e-33 GO:0005515 protein binding
1.06 2.02e-21 GO:0005488 binding
1.14 3.07e-06 GO:0000166 nucleotide binding
1.14 4.61e-05 GO:0017076 purine nucleotide binding
1.14 4.82e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.14 5.20e-05 GO:0032553 ribonucleotide binding
1.14 5.20e-05 GO:0032555 purine ribonucleotide binding
1.32 1.43e-04 GO:0000988 protein binding transcription factor activity
1.32 1.43e-04 GO:0000989 transcription factor binding transcription factor activity
1.31 1.90e-04 GO:0003712 transcription cofactor activity
1.20 2.16e-03 GO:0019899 enzyme binding
1.26 2.53e-03 GO:0019904 protein domain specific binding
1.23 6.82e-03 GO:0008092 cytoskeletal protein binding
1.06 1.14e-02 GO:0003824 catalytic activity
1.34 1.31e-02 GO:0003713 transcription coactivator activity
1.26 1.75e-02 GO:0005525 GTP binding
2.32 2.91e-02 GO:0070412 R-SMAD binding