Motif ID: POU5F1.p2

Z-value: 0.731


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.411.1e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_64922420 4.787 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_11246934 1.380 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr1_-_153098811 1.359 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_36991189 1.333 NM_001039459
 ELMO1
engulfment and cell motility 1
chr17_-_8756524 1.267 NM_014308
 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr1_+_190552744 1.160 NM_001039152
 RGS21
regulator of G-protein signaling 21
chr21_-_31123797 1.022 NM_181606
 KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr20_-_7869068 0.930 NM_017545
 HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr10_-_98021144 0.902 NM_001114094
NM_013314
 BLNK

B-cell linker

chr3_-_152173475 0.898 NM_001195794
NM_174878
 CLRN1

clarin 1

chr9_+_129066576 0.885 NM_032293
 GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr16_+_23754772 0.837 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr6_-_154692906 0.821 NM_001130699
 IPCEF1
interaction protein for cytohesin exchange factors 1
chr8_+_92330691 0.811 NM_052832
NM_134266
 SLC26A7

solute carrier family 26, member 7

chr5_-_147142249 0.800 JAKMIP2
janus kinase and microtubule interacting protein 2
chr22_+_21318779 0.777 NM_199127
 GGTLC2
gamma-glutamyltransferase light chain 2
chr6_-_33016561 0.776 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_-_86600658 0.760 NM_001007156
NM_001012338
NM_002530
 NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr1_+_66230977 0.748 NM_001037340
 PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_122901543 0.741 GRAMD1B
GRAM domain containing 1B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
3.72 1.21e-02 GO:0050909 sensory perception of taste
2.14 1.85e-02 GO:0007517 muscle organ development
1.80 1.06e-03 GO:0007606 sensory perception of chemical stimulus
1.75 5.63e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.71 1.08e-02 GO:0001775 cell activation
1.70 6.93e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.69 8.01e-03 GO:0051253 negative regulation of RNA metabolic process
1.67 3.27e-05 GO:0007600 sensory perception
1.66 3.27e-02 GO:0007417 central nervous system development
1.65 5.84e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.62 1.02e-03 GO:0006955 immune response
1.62 4.71e-03 GO:0010628 positive regulation of gene expression
1.61 2.98e-02 GO:0010629 negative regulation of gene expression
1.60 8.53e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.60 9.20e-03 GO:0030182 neuron differentiation
1.56 1.52e-06 GO:0050877 neurological system process
1.55 1.89e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.51 2.03e-07 GO:0003008 system process
1.47 1.36e-03 GO:0002376 immune system process
1.46 1.52e-04 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.30 5.25e-09 GO:0005886 plasma membrane
1.30 7.12e-09 GO:0071944 cell periphery
1.27 1.36e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
3.46 2.90e-02 GO:0003823 antigen binding
1.91 3.10e-09 GO:0043565 sequence-specific DNA binding
1.73 2.18e-09 GO:0030528 transcription regulator activity
1.72 7.40e-09 GO:0001071 nucleic acid binding transcription factor activity
1.72 7.40e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.65 9.65e-06 GO:0004930 G-protein coupled receptor activity
1.58 1.44e-07 GO:0004888 transmembrane receptor activity
1.55 1.17e-09 GO:0004872 receptor activity
1.50 4.11e-10 GO:0004871 signal transducer activity
1.50 4.11e-10 GO:0060089 molecular transducer activity
1.34 7.01e-05 GO:0003677 DNA binding