Motif ID: POU5F1.p2

Z-value: 0.731


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.411.1e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_64922420 4.787 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_11246934 1.380 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_-_153098811 1.359 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_36991189 1.333 NM_001039459
ELMO1
engulfment and cell motility 1
chr17_-_8756524 1.267 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr1_+_190552744 1.160 NM_001039152
RGS21
regulator of G-protein signaling 21
chr21_-_31123797 1.022 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr20_-_7869068 0.930 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr10_-_98021144 0.902 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_152173475 0.898 NM_001195794
NM_174878
CLRN1

clarin 1

chr9_+_129066576 0.885 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr16_+_23754772 0.837 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr6_-_154692906 0.821 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr8_+_92330691 0.811 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr5_-_147142249 0.800 JAKMIP2
janus kinase and microtubule interacting protein 2
chr22_+_21318779 0.777 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr6_-_33016561 0.776 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr15_-_86600658 0.760 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr1_+_66230977 0.748 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_122901543 0.741 GRAMD1B
GRAM domain containing 1B
chr19_+_14554895 0.736 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr19_-_43800374 0.732 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr14_-_93512818 0.692 ASB2
ankyrin repeat and SOCS box containing 2
chr2_+_214984705 0.690 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr10_+_11247059 0.688 CELF2
CUGBP, Elav-like family member 2
chr19_-_48815853 0.683 NM_182498
ZNF428
zinc finger protein 428
chr5_-_88155360 0.679 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr6_-_155818728 0.673 NM_015718
NOX3
NADPH oxidase 3
chr12_+_111829121 0.649 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr12_+_91620749 0.645 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr11_+_55362802 0.639 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr16_+_12053555 0.638 NM_001080530
SNX29
sorting nexin 29
chr17_-_33179118 0.634 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr19_+_17719504 0.625 NM_001161357
NM_001161358
FCHO1

FCH domain only 1

chr11_+_122901689 0.609 NM_020716
GRAMD1B
GRAM domain containing 1B
chr1_+_33494745 0.606 NM_152493
ZNF362
zinc finger protein 362
chr11_+_128068982 0.587 NM_002017
FLI1
Friend leukemia virus integration 1
chr1_+_190811479 0.579 NM_002922
RGS1
regulator of G-protein signaling 1
chr17_-_16816113 0.575 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr6_+_167456230 0.575 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr12_+_54231249 0.573 NM_001005494
OR6C4
olfactory receptor, family 6, subfamily C, member 4
chr1_+_162795328 0.569 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_134289893 0.567 NM_020815
NM_032961
PCDH10

protocadherin 10

chr7_+_116447527 0.564 ST7
suppression of tumorigenicity 7
chr15_-_91078307 0.562 FAM174B
family with sequence similarity 174, member B
chr20_-_604822 0.562 NM_033129
SCRT2
scratch homolog 2, zinc finger protein (Drosophila)
chr6_-_149847809 0.561 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr2_+_73973600 0.555 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr11_-_3620060 0.548 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr6_-_149847718 0.537 ZC3H12D
zinc finger CCCH-type containing 12D
chr7_-_31347032 0.531 NM_022728
NEUROD6
neurogenic differentiation 6
chr18_+_52965290 0.529 BOD1P
biorientation of chromosomes in cell division 1 pseudogene
chr17_-_59363352 0.526 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr3_+_135996734 0.518 NM_004441
EPHB1
EPH receptor B1
chr17_-_33178987 0.516 HNF1B
HNF1 homeobox B
chr14_-_93512647 0.516 ASB2
ankyrin repeat and SOCS box containing 2
chr1_+_168381811 0.513 NM_001136107
METTL11B
methyltransferase like 11B
chr18_-_59137488 0.510 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr19_+_40511909 0.504 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr4_-_100575313 0.502 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr3_-_129023850 0.498 NM_007283
MGLL
monoglyceride lipase
chr1_+_162795538 0.498 PBX1
pre-B-cell leukemia homeobox 1
chr14_-_106084519 0.497 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_124108672 0.496 NM_020747
ZNF608
zinc finger protein 608
chr10_+_77212524 0.492 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr1_+_179719338 0.482 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr6_+_10663934 0.482 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr3_-_52235218 0.475 NM_017442
TLR9
toll-like receptor 9
chr3_+_135996990 0.474 EPHB1
EPH receptor B1
chr8_-_102872354 0.469 NCALD
neurocalcin delta
chr22_+_21065134 0.465 LOC100290481
immunoglobulin lambda light chain-like
chr15_-_38387410 0.463 NM_004573
PLCB2
phospholipase C, beta 2
chr19_-_17377383 0.457 NM_004335
BST2
bone marrow stromal cell antigen 2
chr17_-_34635446 0.457 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr12_+_25096755 0.455 LRMP
lymphoid-restricted membrane protein
chr2_+_68445821 0.455 NM_002664
PLEK
pleckstrin
chr2_+_5750229 0.454 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr3_+_174598937 0.453 NM_014932
NLGN1
neuroligin 1
chr16_+_23754860 0.450 PRKCB
protein kinase C, beta
chr12_-_49897743 0.447 POU6F1
POU class 6 homeobox 1
chr6_+_10693964 0.445 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_-_133120587 0.442 NM_004665
VNN2
vanin 2
chr6_-_168222645 0.442 NM_024919
FRMD1
FERM domain containing 1
chr13_-_69580459 0.437 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr12_-_10953427 0.436 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr7_-_141320041 0.436 NM_176817
TAS2R38
taste receptor, type 2, member 38
chr1_+_173303616 0.435 NM_022093
TNN
tenascin N
chr1_-_205012348 0.433 NM_000572
IL10
interleukin 10
chr11_+_63829616 0.429 NM_004451
ESRRA
estrogen-related receptor alpha
chr5_-_158459006 0.427 EBF1
early B-cell factor 1
chr19_-_48815572 0.426 ZNF428
zinc finger protein 428
chr5_-_175897430 0.426 RNF44
ring finger protein 44
chr7_-_126670804 0.421 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr5_-_111119846 0.421 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr14_-_56342097 0.420 NM_172337
OTX2
orthodenticle homeobox 2
chr13_-_27572646 0.418 NM_004119
FLT3
fms-related tyrosine kinase 3
chr2_+_17861266 0.417 NM_001105569
MSGN1
mesogenin 1
chr12_-_16321885 0.410 NM_001170798
SLC15A5
solute carrier family 15, member 5
chr17_-_39094787 0.410 NM_001040002
MEOX1
mesenchyme homeobox 1
chr16_+_23754822 0.409 PRKCB
protein kinase C, beta
chr20_+_17155680 0.408 PCSK2
proprotein convertase subtilisin/kexin type 2
chr17_-_38087366 0.408 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr16_+_31273969 0.407 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_+_51837608 0.403 NM_001085479
IQCF3
IQ motif containing F3
chr4_-_41579325 0.400


chrX_-_84521398 0.399 NM_024921
POF1B
premature ovarian failure, 1B
chr1_+_148125090 0.399 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr18_-_54447168 0.399 NM_052947
ALPK2
alpha-kinase 2
chr12_-_7136147 0.391 NM_001733
C1R
complement component 1, r subcomponent
chr16_+_31274030 0.390 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr20_+_17155669 0.390 PCSK2
proprotein convertase subtilisin/kexin type 2
chr1_+_5975345 0.388 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr15_-_78050515 0.388 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr5_-_156322784 0.384 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr6_-_32665409 0.383 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr2_-_50428395 0.381 NM_138735
NRXN1
neurexin 1
chr10_+_124897627 0.381 NM_005519
HMX2
H6 family homeobox 2
chr3_+_99733432 0.380 NM_005290
GPR15
G protein-coupled receptor 15
chr10_+_68355797 0.379 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr12_+_109956210 0.377 NM_015267
CUX2
cut-like homeobox 2
chrX_-_80344096 0.377 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr12_+_25096472 0.374 NM_006152
LRMP
lymphoid-restricted membrane protein
chr7_+_50318801 0.372 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr10_+_106103503 0.371 NM_001008723
CCDC147
coiled-coil domain containing 147
chr7_+_149842850 0.371 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr8_-_72431274 0.366 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr5_-_160211623 0.366 NM_025153
ATP10B
ATPase, class V, type 10B
chr22_-_35938298 0.361 NM_001051
SSTR3
somatostatin receptor 3
chr2_+_189547358 0.361 COL3A1
collagen, type III, alpha 1
chr1_+_5975286 0.360 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr20_-_43693320 0.359 NM_147198
WFDC9
WAP four-disulfide core domain 9
chr7_-_100021658 0.358 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr1_+_154120170 0.358 SYT11
synaptotagmin XI
chr17_-_60988077 0.357 NM_004655
AXIN2
axin 2
chr7_+_73826244 0.355 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr3_-_57209319 0.354 NM_003865
HESX1
HESX homeobox 1
chr6_-_42527760 0.353 NM_033502
TRERF1
transcriptional regulating factor 1
chrX_+_16051344 0.352 NM_005314
GRPR
gastrin-releasing peptide receptor
chr11_+_128069183 0.351 FLI1
Friend leukemia virus integration 1
chr6_-_108252200 0.350 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr9_+_94766379 0.348 FGD3
FYVE, RhoGEF and PH domain containing 3
chr12_-_120502483 0.348 NM_001005366
KDM2B
lysine (K)-specific demethylase 2B
chr5_-_88215034 0.347 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr7_+_116447499 0.346 ST7
suppression of tumorigenicity 7
chr2_-_157890400 0.345 NM_020711
ERMN
ermin, ERM-like protein
chr17_+_60563917 0.344 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr12_+_111829191 0.343 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr6_+_26325124 0.343 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr16_+_23754997 0.342 PRKCB
protein kinase C, beta
chr22_+_30072739 0.338 FLJ20464
hypothetical protein FLJ20464
chr3_+_129124591 0.337 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr3_+_141879555 0.336 NM_152616
TRIM42
tripartite motif containing 42
chr2_+_73973640 0.336 ACTG2
actin, gamma 2, smooth muscle, enteric
chr14_+_31868229 0.335 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_44249379 0.335 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr17_+_60563963 0.335 RGS9
regulator of G-protein signaling 9
chr7_-_3049872 0.334 NM_032415
CARD11
caspase recruitment domain family, member 11
chr3_-_193928038 0.333 NM_004113
FGF12
fibroblast growth factor 12
chr12_-_103846186 0.333 NM_032148
SLC41A2
solute carrier family 41, member 2
chr8_-_72437020 0.333 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr7_-_27206249 0.332 NM_000522
HOXA13
homeobox A13
chr6_+_29187565 0.331 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr14_+_78815406 0.330 NM_001105250
NM_138970
NRXN3

neurexin 3

chr8_+_144711619 0.329 NM_024736
GSDMD
gasdermin D
chr22_-_30072329 0.328 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr5_-_66528330 0.327 NM_005582
CD180
CD180 molecule
chr12_-_7709734 0.326 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr22_+_20715340 0.326


chr12_-_101398429 0.326 IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_-_100021689 0.323 NM_002319
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_+_29902734 0.322 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr10_+_120957084 0.322 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr9_-_35069751 0.322 NM_004629
FANCG
Fanconi anemia, complementation group G
chr11_-_10630408 0.321 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr3_+_185300660 0.320 NM_182589
HTR3E
5-hydroxytryptamine (serotonin) receptor 3, family member E
chr14_+_99555471 0.320 EVL
Enah/Vasp-like
chr1_+_165564904 0.319 NM_001198783
POU2F1
POU class 2 homeobox 1
chr11_+_128069203 0.318 FLI1
Friend leukemia virus integration 1
chr12_-_51086330 0.318 NM_033033
KRT82
keratin 82
chr18_+_40513889 0.318 NM_001130110
SETBP1
SET binding protein 1
chr17_+_9670105 0.315 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr11_+_4522993 0.315 NM_001004137
OR52M1
olfactory receptor, family 52, subfamily M, member 1
chr1_-_158948176 0.314 NM_001778
CD48
CD48 molecule
chr22_-_30072217 0.313 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr1_+_100957883 0.313 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr12_-_101398470 0.313 IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_-_70639382 0.310 NM_014595
NT5C
5', 3'-nucleotidase, cytosolic
chr14_-_105851580 0.310 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_84521320 0.310 POF1B
premature ovarian failure, 1B
chr17_-_23151601 0.309 NM_000625
NOS2
nitric oxide synthase 2, inducible
chr14_-_88948486 0.309 FOXN3
forkhead box N3
chr8_+_11388918 0.308 NM_001715
BLK
B lymphoid tyrosine kinase
chr6_-_11340886 0.308 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_+_135558744 0.303 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr15_+_58083712 0.302 NM_012182
FOXB1
forkhead box B1
chr14_-_106184988 0.302 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_100021862 0.300 NM_033506
FBXO24
F-box protein 24
chr1_+_218930250 0.300 NM_024709
C1orf115
chromosome 1 open reading frame 115
chrX_+_28515479 0.298 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr8_+_19840861 0.297 NM_000237
LPL
lipoprotein lipase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 1.21e-12 GO:0032501 multicellular organismal process
1.24 5.87e-09 GO:0050896 response to stimulus
1.51 2.03e-07 GO:0003008 system process
1.56 1.52e-06 GO:0050877 neurological system process
1.18 3.27e-06 GO:0050789 regulation of biological process
1.32 6.60e-06 GO:0048856 anatomical structure development
1.18 6.81e-06 GO:0050794 regulation of cellular process
1.16 9.91e-06 GO:0065007 biological regulation
1.67 3.27e-05 GO:0007600 sensory perception
1.33 3.56e-05 GO:0048731 system development
1.60 8.53e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 1.13e-04 GO:0032502 developmental process
1.37 1.41e-04 GO:0006355 regulation of transcription, DNA-dependent
1.46 1.52e-04 GO:0007399 nervous system development
1.28 1.88e-04 GO:0007275 multicellular organismal development
1.35 2.28e-04 GO:0051252 regulation of RNA metabolic process
1.32 7.52e-04 GO:0010468 regulation of gene expression
1.62 1.02e-03 GO:0006955 immune response
1.80 1.06e-03 GO:0007606 sensory perception of chemical stimulus
1.47 1.36e-03 GO:0002376 immune system process
1.36 2.73e-03 GO:0048513 organ development
1.31 2.96e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.28 4.26e-03 GO:0048518 positive regulation of biological process
1.62 4.71e-03 GO:0010628 positive regulation of gene expression
1.23 4.85e-03 GO:0023052 signaling
1.28 5.55e-03 GO:0031326 regulation of cellular biosynthetic process
1.75 5.63e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.65 5.84e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.70 6.93e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.28 7.30e-03 GO:0009889 regulation of biosynthetic process
1.69 8.01e-03 GO:0051253 negative regulation of RNA metabolic process
1.29 8.86e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.60 9.20e-03 GO:0030182 neuron differentiation
1.27 9.46e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.71 1.08e-02 GO:0001775 cell activation
3.72 1.21e-02 GO:0050909 sensory perception of taste
1.27 1.52e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 1.81e-02 GO:0007166 cell surface receptor linked signaling pathway
2.14 1.85e-02 GO:0007517 muscle organ development
1.55 1.89e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.61 2.98e-02 GO:0010629 negative regulation of gene expression
1.66 3.27e-02 GO:0007417 central nervous system development
1.22 3.84e-02 GO:0007165 signal transduction
1.21 4.51e-02 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 5.25e-09 GO:0005886 plasma membrane
1.30 7.12e-09 GO:0071944 cell periphery
1.27 1.36e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.50 4.11e-10 GO:0004871 signal transducer activity
1.50 4.11e-10 GO:0060089 molecular transducer activity
1.55 1.17e-09 GO:0004872 receptor activity
1.73 2.18e-09 GO:0030528 transcription regulator activity
1.91 3.10e-09 GO:0043565 sequence-specific DNA binding
1.72 7.40e-09 GO:0001071 nucleic acid binding transcription factor activity
1.72 7.40e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.58 1.44e-07 GO:0004888 transmembrane receptor activity
1.65 9.65e-06 GO:0004930 G-protein coupled receptor activity
1.34 7.01e-05 GO:0003677 DNA binding
3.46 2.90e-02 GO:0003823 antigen binding