Motif ID: FOXA2.p3

Z-value: 1.604


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXA2chr20_-_225130500.591.6e-02Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_69716298 2.119 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr17_+_69939130 2.061 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_6746763 1.915 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr1_-_167822334 1.720 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr1_-_167822248 1.716 F5
coagulation factor V (proaccelerin, labile factor)
chr17_-_61655915 1.698 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_+_50699965 1.602 HLF
hepatic leukemia factor
chr10_-_49152918 1.458 NM_001018071
FRMPD2
FERM and PDZ domain containing 2
chr4_+_187424111 1.433 NM_000128
F11
coagulation factor XI
chr1_+_103961476 1.423 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr1_-_57204208 1.391 NM_000066
C8B
complement component 8, beta polypeptide
chr14_-_93859394 1.349 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr7_-_50596238 1.321 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr14_-_20563722 1.301 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr4_+_75393053 1.295 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr12_+_99391681 1.294 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr2_+_113601616 1.248 IL1RN
interleukin 1 receptor antagonist
chr6_-_41823056 1.247 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr14_-_20563698 1.231 NDRG2
NDRG family member 2
chr20_-_41788975 1.228 NM_001008901
NM_176791
GTSF1L

gametocyte specific factor 1-like

chr7_+_94953148 1.226 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr3_+_46628928 1.221 NM_001195442
LOC100132146
hypothetical LOC100132146
chr20_-_48741481 1.198


chr9_-_14900992 1.180 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chrX_-_65176564 1.161 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr2_-_21079145 1.149 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_+_113601608 1.139 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr16_+_54782802 1.114 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr12_+_99391870 1.105 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_-_10479810 1.070 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr1_+_86707113 1.062 NM_001285
CLCA1
chloride channel accessory 1
chr16_-_87570716 1.049 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_+_212228482 1.034 NM_002763
PROX1
prospero homeobox 1
chr11_-_55757236 1.017 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr22_+_33792125 1.003 NM_001008494
ISX
intestine-specific homeobox
chr20_+_29492071 0.999 NM_153324
DEFB123
defensin, beta 123
chr5_+_27508139 0.988 LOC643401
hypothetical protein LOC643401
chr19_-_59003770 0.982 NM_033297
NLRP12
NLR family, pyrin domain containing 12
chr2_+_113591940 0.978 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr10_-_48036698 0.970 NM_016204
GDF2
growth differentiation factor 2
chr11_-_116168316 0.968 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr14_-_37134050 0.964 FOXA1
forkhead box A1
chr8_-_81155564 0.961 NM_001025252
TPD52
tumor protein D52
chr3_-_191650291 0.955 NM_207316
TMEM207
transmembrane protein 207
chr9_-_94226380 0.943 NM_005014
OMD
osteomodulin
chr1_+_16203317 0.937 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr2_-_21081694 0.931 APOB
apolipoprotein B (including Ag(x) antigen)
chr9_-_111230926 0.924 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_34997928 0.910 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr3_-_121884091 0.905 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr3_+_64645819 0.893 LOC100507098
hypothetical LOC100507098
chr6_-_26038817 0.891 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr3_+_187813553 0.891 AHSG
alpha-2-HS-glycoprotein
chrX_-_55074125 0.888 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr2_-_165133239 0.884 GRB14
growth factor receptor-bound protein 14
chr21_-_30510113 0.864 NM_199328
CLDN8
claudin 8
chr7_-_104354325 0.861 LOC723809
hypothetical LOC723809
chr4_-_104160291 0.858 NM_001100874
NM_139173
NHEDC1

Na+/H+ exchanger domain containing 1

chr10_+_118177371 0.854 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr3_-_150422474 0.846 NM_000096
CP
ceruloplasmin (ferroxidase)
chr3_-_121883647 0.842 HGD
homogentisate 1,2-dioxygenase
chr11_-_117640078 0.842


chr13_+_77007809 0.824 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr17_-_23721351 0.819 VTN
vitronectin
chr1_+_86662356 0.810 NM_006536
CLCA2
chloride channel accessory 2
chr7_-_107230867 0.804 NM_000111
SLC26A3
solute carrier family 26, member 3
chr14_+_36200867 0.798 PAX9
paired box 9
chr16_-_86527608 0.797 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr11_+_55319607 0.796 NM_001004735
OR5D14
olfactory receptor, family 5, subfamily D, member 14
chr8_+_124263932 0.796 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr3_-_194579207 0.795 NM_198505
ATP13A5
ATPase type 13A5
chr1_+_150753601 0.792 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr1_-_229627412 0.781 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr10_+_7785290 0.772 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_70180805 0.759 NM_053039
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr12_-_9159780 0.755 A2M
alpha-2-macroglobulin
chr11_-_5178505 0.752 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr11_+_61943082 0.750 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr2_-_166638376 0.747 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr6_+_32003180 0.746 NM_000063
NM_001145903
C2

complement component 2

chr10_+_7785235 0.746 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 0.743 ITIH2
inter-alpha (globulin) inhibitor H2
chr6_+_62341966 0.742 NM_001190706
MTRNR2L9
MT-RNR2-like 9
chr10_+_7785347 0.741 ITIH2
inter-alpha (globulin) inhibitor H2
chr6_-_134415311 0.740 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr8_+_87947788 0.733 NM_173538
CNBD1
cyclic nucleotide binding domain containing 1
chr3_+_152970904 0.730 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr17_-_23721430 0.729 VTN
vitronectin
chr8_+_17866373 0.720 PCM1
pericentriolar material 1
chr10_-_54201400 0.719 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr11_+_5431213 0.718 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr7_+_142850667 0.714 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr6_-_49820030 0.712 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr14_-_36052727 0.706 NM_001101341
SFTA3
surfactant associated 3
chr10_+_7785360 0.706 ITIH2
inter-alpha (globulin) inhibitor H2
chrX_+_65299352 0.704 HEPH
hephaestin
chr7_+_113513828 0.703 FOXP2
forkhead box P2
chr2_-_21120314 0.699 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_+_36200815 0.699 PAX9
paired box 9
chr10_-_69267774 0.693 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr12_-_9159742 0.688 A2M
alpha-2-macroglobulin
chr3_+_179759181 0.688 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_+_101532544 0.680 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr5_-_39238818 0.667 FYB
FYN binding protein
chr1_+_61315378 0.667


chrX_+_65299157 0.666 NM_138737
HEPH
hephaestin
chr12_-_9159707 0.666 A2M
alpha-2-macroglobulin
chr6_-_155818728 0.665 NM_015718
NOX3
NADPH oxidase 3
chr3_+_187813538 0.662 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr1_-_115039614 0.658 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr17_-_23721420 0.655 VTN
vitronectin
chr6_-_31953425 0.654 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr20_+_54257194 0.652 NM_019888
MC3R
melanocortin 3 receptor
chr2_+_71016503 0.645 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr1_-_109651140 0.644 NM_001010985
MYBPHL
myosin binding protein H-like
chrX_-_133620103 0.641 NM_021796
PLAC1
placenta-specific 1
chr5_+_76470829 0.640


chr20_-_49612745 0.628 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr9_-_70780574 0.627


chrX_+_26066380 0.626 NM_173699
MAGEB18
melanoma antigen family B, 18
chr7_+_80105718 0.620 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr17_-_23721468 0.620 VTN
vitronectin
chr1_+_13784553 0.620 NM_001006624
NM_001006625
PDPN

podoplanin

chr12_-_642786 0.615 NM_016533
NINJ2
ninjurin 2
chrX_-_111809929 0.612 NM_178175
LHFPL1
lipoma HMGIC fusion partner-like 1
chr6_+_64403668 0.603 PHF3
PHD finger protein 3
chr2_-_167058901 0.601 SCN7A
sodium channel, voltage-gated, type VII, alpha
chr6_+_26359805 0.597 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr7_+_80105907 0.596 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_129693938 0.590 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr2_-_170138558 0.589 NM_024622
FASTKD1
FAST kinase domains 1
chr1_+_220977180 0.588 NM_207468
FAM177B
family with sequence similarity 177, member B
chr7_+_80069439 0.585 NM_001001547
CD36
CD36 molecule (thrombospondin receptor)
chr4_+_187424336 0.583 F11
coagulation factor XI
chr2_+_132196533 0.574 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr11_+_22652894 0.571 NM_005256
GAS2
growth arrest-specific 2
chr1_-_28376041 0.566 NM_000952
PTAFR
platelet-activating factor receptor
chr5_+_57823017 0.565 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr1_-_236120844 0.564 NM_021186
ZP4
zona pellucida glycoprotein 4
chr10_+_47875229 0.563 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr4_+_71096830 0.561 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr1_-_205272619 0.560 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr18_-_50777634 0.558 NM_025214
CCDC68
coiled-coil domain containing 68
chr1_-_159459999 0.557 NM_001643
APOA2
apolipoprotein A-II
chr17_+_70443408 0.556 NM_178233
OTOP3
otopetrin 3
chr1_+_171871283 0.553 NM_001195190
LOC730159
hypothetical protein LOC730159
chr2_-_21084911 0.547 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_+_154855709 0.547 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr4_+_88939725 0.543 NM_004967
IBSP
integrin-binding sialoprotein
chr17_-_6958695 0.542 ASGR2
asialoglycoprotein receptor 2
chr17_-_6958773 0.534 NM_001181
NM_080912
NM_080913
ASGR2


asialoglycoprotein receptor 2


chr17_+_36647795 0.532 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr11_-_93866554 0.524 NM_005590
NM_005591
MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

chr4_-_64957595 0.523 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr9_-_110658030 0.523 NM_006686
ACTL7B
actin-like 7B
chr7_-_25234582 0.522 NM_022150
NPVF
neuropeptide VF precursor
chr4_-_70396167 0.519 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr1_+_205344200 0.518 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr2_+_201464884 0.516 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr4_+_155703581 0.516 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr8_-_107023 0.513 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr2_-_21084077 0.511 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_1346465 0.510 NM_001145210
LOC441869
hypothetical protein LOC441869
chr2_+_38009405 0.509 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chrX_-_154216929 0.506 NM_001289
CLIC2
chloride intracellular channel 2
chr8_-_57395794 0.503 NM_138969
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr17_+_3326045 0.500 NM_000049
ASPA
aspartoacylase
chr11_+_51371857 0.498 NM_001004703
OR4C46
olfactory receptor, family 4, subfamily C, member 46
chr9_-_34700062 0.497 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr20_-_49612574 0.497 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr10_+_18729518 0.494 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_26266311 0.493 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr12_-_9159789 0.491 NM_000014
A2M
alpha-2-macroglobulin
chr3_+_195336631 0.485 HES1
hairy and enhancer of split 1, (Drosophila)
chr5_-_36337756 0.485 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr16_+_29697090 0.484 ZG16
zymogen granule protein 16 homolog (rat)
chr20_+_31334601 0.479 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr2_-_21120398 0.478 APOB
apolipoprotein B (including Ag(x) antigen)
chr7_+_94377145 0.478 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr14_+_38772870 0.477 NM_054024
MIA2
melanoma inhibitory activity 2
chr17_-_23721485 0.477 NM_000638
VTN
vitronectin
chr3_+_2117246 0.474 NM_175607
CNTN4
contactin 4
chr12_-_101835026 0.474 PAH
phenylalanine hydroxylase
chr11_-_26700121 0.473 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr7_+_142590633 0.473 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr1_-_115102084 0.473 CSDE1
cold shock domain containing E1, RNA-binding
chr19_-_60941551 0.473 NM_176820
NLRP9
NLR family, pyrin domain containing 9
chr1_-_115102109 0.472 CSDE1
cold shock domain containing E1, RNA-binding
chr2_-_39201631 0.472 SOS1
son of sevenless homolog 1 (Drosophila)
chr4_+_70896236 0.472 NM_001009181
NM_003154
STATH

statherin

chr12_+_56230110 0.472 NM_004984
KIF5A
kinesin family member 5A
chr2_+_170149348 0.471 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr1_-_145163520 0.469 FMO5
flavin containing monooxygenase 5
chr4_+_88748704 0.467 NM_014208
DSPP
dentin sialophosphoprotein
chr2_+_234191029 0.466 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr15_+_64661560 0.466


chr4_-_71751070 0.465 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_11591692 0.462 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_142175329 0.455 SLC25A36
solute carrier family 25, member 36
chr4_-_155531898 0.454 NM_017639
DCHS2
dachsous 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.49 6.11e-09 GO:0007606 sensory perception of chemical stimulus
2.00 1.31e-07 GO:0007600 sensory perception
2.41 6.16e-07 GO:0007608 sensory perception of smell
1.63 6.49e-07 GO:0003008 system process
1.66 1.13e-05 GO:0050877 neurological system process
1.27 5.04e-05 GO:0032501 multicellular organismal process
1.23 1.02e-04 GO:0050896 response to stimulus
5.45 2.19e-04 GO:0031214 biomineral tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.61 2.18e-09 GO:0005576 extracellular region
1.27 2.21e-04 GO:0071944 cell periphery
1.27 3.38e-04 GO:0005886 plasma membrane
1.59 1.18e-03 GO:0044421 extracellular region part
1.20 2.17e-03 GO:0031224 intrinsic to membrane
1.20 3.46e-03 GO:0016021 integral to membrane
1.18 3.93e-03 GO:0044425 membrane part
1.61 8.22e-03 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.99 2.02e-08 GO:0004930 G-protein coupled receptor activity
2.40 5.09e-07 GO:0004984 olfactory receptor activity
1.58 1.61e-06 GO:0004872 receptor activity
1.68 2.97e-06 GO:0004888 transmembrane receptor activity
1.41 8.84e-04 GO:0004871 signal transducer activity
1.41 8.84e-04 GO:0060089 molecular transducer activity