Motif ID: NR5A1,2.p2

Z-value: 1.750


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR5A1chr9_-_1263095100.467.6e-02Click!
NR5A2chr1_+_198263352-0.332.1e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_145725197 1.764 NM_001001795
 C8orf82
chromosome 8 open reading frame 82
chr3_+_50281582 1.526 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr5_+_176449156 1.476 NM_022963
 FGFR4
fibroblast growth factor receptor 4
chr12_-_119038941 1.470 RAB35
RAB35, member RAS oncogene family
chr16_-_65510230 1.357 NM_004062
 CDH16
cadherin 16, KSP-cadherin
chr12_-_9123126 1.339 A2M
alpha-2-macroglobulin
chr10_-_21826211 1.280 NM_001010911
 C10orf114
chromosome 10 open reading frame 114
chr10_-_21826192 1.241 C10orf114
chromosome 10 open reading frame 114
chr16_-_65781499 1.236 NM_178516
 EXOC3L1
exocyst complex component 3-like 1
chr19_+_540849 1.224 NM_001194
 HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr17_-_35774467 1.215 NM_152219
 GJD3
gap junction protein, delta 3, 31.9kDa
chr22_+_40195058 1.192 NM_001098
 ACO2
aconitase 2, mitochondrial
chr3_+_50281309 1.183 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_+_2279679 1.179 SPPL2B
signal peptide peptidase-like 2B
chr15_+_60838053 1.153 TLN2
talin 2
chr5_+_94981735 1.118 NM_199243
 GPR150
G protein-coupled receptor 150
chr18_-_28606839 1.118 NM_020805
 KLHL14
kelch-like 14 (Drosophila)
chr8_-_145725289 1.111 C8orf82
chromosome 8 open reading frame 82
chr12_+_6768966 1.104 CD4
CD4 molecule
chr1_+_17817397 1.075 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
4.84 4.52e-02 GO:0048041 focal adhesion assembly
1.74 1.38e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.64 4.56e-03 GO:0032583 regulation of gene-specific transcription
1.62 3.58e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.52 5.78e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.49 3.21e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.46 3.75e-02 GO:0010628 positive regulation of gene expression
1.46 3.82e-02 GO:0051254 positive regulation of RNA metabolic process
1.45 1.01e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.44 2.26e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 1.70e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.41 2.73e-02 GO:0009891 positive regulation of biosynthetic process
1.39 1.31e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.39 2.70e-02 GO:0022008 neurogenesis
1.35 6.65e-04 GO:0009653 anatomical structure morphogenesis
1.34 2.38e-02 GO:0031325 positive regulation of cellular metabolic process
1.33 4.32e-03 GO:0007399 nervous system development
1.30 2.41e-04 GO:0065008 regulation of biological quality
1.30 3.37e-04 GO:0030154 cell differentiation
1.29 2.97e-06 GO:0048731 system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
5.02 1.37e-02 GO:0005833 hemoglobin complex
2.13 2.84e-02 GO:0005925 focal adhesion
1.87 6.32e-04 GO:0016323 basolateral plasma membrane
1.44 1.12e-03 GO:0005615 extracellular space
1.43 2.82e-02 GO:0030054 cell junction
1.37 1.67e-03 GO:0044421 extracellular region part
1.28 1.70e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.67 6.66e-03 GO:0016563 transcription activator activity
1.49 3.72e-03 GO:0005198 structural molecule activity
1.35 1.22e-02 GO:0030528 transcription regulator activity
1.10 2.97e-03 GO:0005515 protein binding