Motif ID: FOXD3.p2

Z-value: 1.244


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD3chr1_+_63561317-0.543.0e-02Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_47584159 2.096 NM_033124
CCDC65
coiled-coil domain containing 65
chr6_+_150304813 2.078 NM_025217
ULBP2
UL16 binding protein 2
chr5_+_40877053 1.789 NM_032587
CARD6
caspase recruitment domain family, member 6
chr20_+_19818209 1.719 NM_018993
RIN2
Ras and Rab interactor 2
chr12_+_27066749 1.498 NM_004264
MED21
mediator complex subunit 21
chr12_+_27066768 1.433 MED21
mediator complex subunit 21
chr18_+_27281729 1.421 NM_001944
DSG3
desmoglein 3
chr4_+_89519004 1.342 HERC6
hect domain and RLD 6
chr2_-_218739891 1.335 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr10_+_118177371 1.330 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr3_+_138159396 1.232 NM_144717
IL20RB
interleukin 20 receptor beta
chr19_-_55358091 1.164 NM_152358
IZUMO2
IZUMO family member 2
chr14_-_98807307 1.090 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr3_-_64186151 1.089 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr20_+_19863716 1.059 RIN2
Ras and Rab interactor 2
chr19_-_4782711 1.058 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr13_-_85271329 1.055 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr4_+_89518898 1.048 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chrX_-_77801480 1.040 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_+_108578877 0.981 NM_032600
CCDC54
coiled-coil domain containing 54
chr17_+_58440629 0.946 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_-_138552517 0.923 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr3_-_171070314 0.893 NM_024727
LRRC31
leucine rich repeat containing 31
chr18_+_59405513 0.893 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_+_190990142 0.892 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr18_-_65766068 0.890 CD226
CD226 molecule
chr19_+_57564981 0.886 NM_001145434
ZNF880
zinc finger protein 880
chr1_+_181421796 0.880 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr12_+_45896318 0.861 NM_138371
FAM113B
family with sequence similarity 113, member B
chrX_-_15312390 0.860 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr1_-_67366807 0.860 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr11_-_128399218 0.839 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr7_+_151284396 0.836 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr2_-_227952249 0.833 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr7_+_28441758 0.823 NM_004904
CREB5
cAMP responsive element binding protein 5
chr1_+_43837096 0.814 PTPRF
protein tyrosine phosphatase, receptor type, F
chr6_+_121798443 0.798 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr12_+_55201854 0.792 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_+_104093962 0.775 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr21_+_39117064 0.774 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr2_+_201182187 0.769 AOX1
aldehyde oxidase 1
chr9_+_74956494 0.761 NM_000700
ANXA1
annexin A1
chr16_+_67235651 0.752 NM_001793
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr2_-_215998181 0.751 FN1
fibronectin 1
chr4_-_70861301 0.746 NM_001891
CSN2
casein beta
chr19_+_12995782 0.739 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_58625086 0.735 TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_+_167013859 0.733 NM_012464
TLL1
tolloid-like 1
chr3_-_127810087 0.732 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr14_-_80934523 0.731 NM_033104
STON2
stonin 2
chr5_+_161208475 0.725 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_+_123062143 0.722 STAG2
stromal antigen 2
chr4_+_75393053 0.722 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr21_+_38550739 0.698 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_+_22375753 0.692 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr3_-_191321367 0.690 LEPREL1
leprecan-like 1
chr22_+_43527101 0.687 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr1_-_159474503 0.682 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr2_-_72228427 0.677 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr3_+_195336625 0.673 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr19_-_51319769 0.673 NM_207393
IGFL3
IGF-like family member 3
chr5_+_145296313 0.671 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr10_+_124135574 0.659 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_+_46799279 0.657 NM_000289
PFKM
phosphofructokinase, muscle
chr18_+_8708448 0.654


chr11_+_48194937 0.648 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr4_-_123596921 0.644 NM_000586
IL2
interleukin 2
chrX_+_154880439 0.641 NM_002186
IL9R
interleukin 9 receptor
chr17_+_45617676 0.635


chr11_+_12265022 0.635 NM_032867
MICALCL
MICAL C-terminal like
chr12_+_21175394 0.633 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr19_-_47623340 0.630 NM_005357
LIPE
lipase, hormone-sensitive
chr9_+_74956601 0.626 ANXA1
annexin A1
chr1_-_166373434 0.625 GPR161
G protein-coupled receptor 161
chr5_+_173405343 0.625 HMP19
HMP19 protein
chr5_+_96237923 0.623 ERAP2
endoplasmic reticulum aminopeptidase 2
chr10_-_95231933 0.621 NM_013451
NM_133337
MYOF

myoferlin

chr5_-_24680841 0.620 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr2_-_80384997 0.618 NM_178839
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr11_+_60016826 0.617 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr9_-_116920232 0.613 NM_002160
TNC
tenascin C
chr9_+_74956614 0.612 ANXA1
annexin A1
chr17_+_53587492 0.611 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr11_+_122214415 0.610 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr12_+_26017954 0.610 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_74473672 0.607 NM_015978
TNNI3K
TNNI3 interacting kinase
chr9_+_78305368 0.605 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr4_+_26194643 0.598 NM_018317
TBC1D19
TBC1 domain family, member 19
chr8_+_67201684 0.594 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr20_-_14266200 0.589 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr9_+_21430439 0.587 NM_024013
IFNA1
interferon, alpha 1
chr4_+_72321113 0.585 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr20_+_54533191 0.583 NM_001012971
C20orf106
C20orf107
chromosome 20 open reading frame 106
chromosome 20 open reading frame 107
chr3_+_38282301 0.583 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr11_-_102250876 0.576 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr2_-_160765008 0.572 ITGB6
integrin, beta 6
chrX_+_50044279 0.564 NM_033031
NM_033670
CCNB3

cyclin B3

chr5_+_159368733 0.564 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr1_+_156229686 0.562 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr14_-_98807574 0.560 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr1_+_218768170 0.554 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr6_+_45404031 0.554 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr10_-_32707549 0.549 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr3_+_11242666 0.546 NM_001098211
HRH1
histamine receptor H1
chr2_-_213723298 0.544 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr16_+_27248806 0.542 IL4R
interleukin 4 receptor
chr3_-_191321601 0.541 NM_018192
LEPREL1
leprecan-like 1
chrX_-_10495476 0.537 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr9_-_4290028 0.536 NM_001042413
GLIS3
GLIS family zinc finger 3
chr8_-_116749382 0.535 TRPS1
trichorhinophalangeal syndrome I
chr11_-_63087430 0.535 NM_017878
HRASLS2
HRAS-like suppressor 2
chr15_+_40484249 0.534 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr16_-_4757125 0.530 NM_021646
ZNF500
zinc finger protein 500
chr8_+_39890484 0.530 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr8_-_95343696 0.527 GEM
GTP binding protein overexpressed in skeletal muscle
chr17_+_7883076 0.521 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr11_-_55128424 0.519 NM_001004700
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr6_+_83129641 0.518 NM_006670
TPBG
trophoblast glycoprotein
chr19_-_13478037 0.517 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_+_59820413 0.515 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr4_+_3285671 0.515 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr7_+_113842470 0.512 FOXP2
forkhead box P2
chr4_-_90978469 0.512 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_13784553 0.509 NM_001006624
NM_001006625
PDPN

podoplanin

chr3_-_194118321 0.507 MB21D2
Mab-21 domain containing 2
chr2_-_121759237 0.496 NM_014553
TFCP2L1
transcription factor CP2-like 1
chrX_+_21960841 0.495 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_+_148747110 0.495 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr13_-_98708549 0.493 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr7_-_87687276 0.493 SRI
sorcin
chr11_-_121492010 0.490 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr2_-_215605054 0.487 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr3_+_195336631 0.484 HES1
hairy and enhancer of split 1, (Drosophila)
chr3_+_44667504 0.481 ZNF35
zinc finger protein 35
chrX_+_115215985 0.475 NM_000686
AGTR2
angiotensin II receptor, type 2
chr18_+_59705918 0.473 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr12_+_70618892 0.472 NM_173353
TPH2
tryptophan hydroxylase 2
chr13_-_40491491 0.468 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_28418668 0.467 NM_182898
CREB5
cAMP responsive element binding protein 5
chr9_-_21325239 0.461 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chr9_-_14076901 0.460 NFIB
nuclear factor I/B
chr5_+_140552087 0.458 NM_018930
PCDHB10
protocadherin beta 10
chr12_-_41163680 0.456 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr9_-_4289915 0.455 GLIS3
GLIS family zinc finger 3
chr1_+_107485071 0.454 NTNG1
netrin G1
chr5_+_140146059 0.453 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr19_-_61876057 0.451 NM_001005850
ZNF835
zinc finger protein 835
chr1_+_218768146 0.448 MARK1
MAP/microtubule affinity-regulating kinase 1
chr15_+_92700167 0.448 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr15_-_61460967 0.447 CA12
carbonic anhydrase XII
chr2_-_189752575 0.445 NM_000393
COL5A2
collagen, type V, alpha 2
chrX_+_2934653 0.444 NM_001011719
ARSH
arylsulfatase family, member H
chr2_-_40593074 0.442 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_-_73095396 0.442 NM_203309
HEATR4
HEAT repeat containing 4
chr17_-_7471832 0.440 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr1_+_34993234 0.437 NM_005268
GJB5
gap junction protein, beta 5, 31.1kDa
chr5_+_159368721 0.436 TTC1
tetratricopeptide repeat domain 1
chr3_+_190831909 0.435 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr18_+_59571256 0.435 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_+_13240987 0.434 EMP1
epithelial membrane protein 1
chr7_+_136849104 0.434 RPL41P5
ribosomal protein L41 pseudogene 5
chr9_+_130719034 0.433 LRRC8A
leucine rich repeat containing 8 family, member A
chr22_+_40372957 0.432 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr6_-_136889302 0.432 MAP7
microtubule-associated protein 7
chr1_-_42738535 0.431 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr15_-_61461127 0.431 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr12_-_52868855 0.430 NM_014311
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr19_+_14460757 0.428 NM_001146693
LOC100130932
small nuclear ribonucleoprotein G-like protein
chr11_-_107969554 0.424 NM_015065
EXPH5
exophilin 5
chr4_-_77097582 0.423 SDAD1
SDA1 domain containing 1
chr4_+_71096830 0.422 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr1_-_166373351 0.422 GPR161
G protein-coupled receptor 161
chr1_-_151852128 0.422 NM_080388
S100A16
S100 calcium binding protein A16
chr4_+_69465107 0.419 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr14_-_60818263 0.418 NM_001017970
TMEM30B
transmembrane protein 30B
chr18_-_46068689 0.414 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr9_+_5500544 0.414 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr19_-_5797465 0.413 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr9_-_109291575 0.413 KLF4
Kruppel-like factor 4 (gut)
chr4_-_153820535 0.409 NM_152680
TMEM154
transmembrane protein 154
chr7_-_16471817 0.409 NM_015464
SOSTDC1
sclerostin domain containing 1
chr11_+_55174953 0.408 NM_001004059
OR4S2
olfactory receptor, family 4, subfamily S, member 2
chr8_+_26569709 0.406 DPYSL2
dihydropyrimidinase-like 2
chr12_-_120220493 0.406 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr2_-_160764819 0.403 NM_000888
ITGB6
integrin, beta 6
chrX_+_135210787 0.401 NM_153834
GPR112
G protein-coupled receptor 112
chr4_+_100957003 0.399 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr3_+_171022403 0.396 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr9_-_109291866 0.395 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chrX_+_100241453 0.391 NM_006733
CENPI
centromere protein I
chr1_-_166373159 0.391 GPR161
G protein-coupled receptor 161
chr11_+_101488380 0.390 NM_001195045
YAP1
Yes-associated protein 1
chr19_-_9087438 0.390 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr18_+_27152049 0.389 NM_001942
DSG1
desmoglein 1
chr12_-_28016182 0.389 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr10_+_47216925 0.388 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr2_-_151052391 0.388 NM_005168
RND3
Rho family GTPase 3
chr19_-_49644470 0.387 NM_014518
ZNF229
zinc finger protein 229
chr12_+_20854904 0.386 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr15_+_30721161 0.386 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.55 2.93e-02 GO:0007608 sensory perception of smell

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 6.50e-03 GO:0005886 plasma membrane
1.14 1.22e-02 GO:0071944 cell periphery
1.98 2.38e-02 GO:0044420 extracellular matrix part
1.55 3.62e-02 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.59 3.23e-03 GO:0004984 olfactory receptor activity