Motif ID: ALX1.p2

Z-value: 0.655


Transcription factors associated with ALX1.p2:

Gene SymbolEntrez IDGene Name
ALX1 8092 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ALX1chr12_+_841980150.504.9e-02Click!


Activity profile for motif ALX1.p2.

activity profile for motif ALX1.p2


Sorted Z-values histogram for motif ALX1.p2

Sorted Z-values for motif ALX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_41362370 1.285 NM_018643
 TREM1
triggering receptor expressed on myeloid cells 1
chr2_+_132196533 1.139 NM_013310
 C2orf27A
chromosome 2 open reading frame 27A
chrX_-_131089552 0.980 NM_194277
 FRMD7
FERM domain containing 7
chr10_-_23673777 0.972 NM_153714
 C10orf67
chromosome 10 open reading frame 67
chr3_+_63238854 0.914 NM_001130003
 SYNPR
synaptoporin
chr2_+_204279442 0.910 NM_006139
 CD28
CD28 molecule
chr9_+_89687560 0.895 NM_178828
 C9orf79
chromosome 9 open reading frame 79
chr11_-_5212168 0.880 NM_000519
 HBD
hemoglobin, delta
chr7_-_115458010 0.854 NM_001018058
NM_012252
 TFEC

transcription factor EC

chr10_-_42183441 0.849 LOC283027
hypothetical protein LOC283027
chr7_-_107667728 0.845 NM_001037132
 NRCAM
neuronal cell adhesion molecule
chr3_+_122769467 0.843 NM_001012659
 ARGFX
arginine-fifty homeobox
chr1_+_559129 0.820


chr19_+_53450743 0.808


chr3_+_8750485 0.807 NM_033337
NM_001234
 CAV3

caveolin 3

chr6_+_12825818 0.747 NM_030948
 PHACTR1
phosphatase and actin regulator 1
chr11_+_55362802 0.739 NM_001005496
 OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr7_+_22733290 0.731 NM_000600
 IL6
interleukin 6 (interferon, beta 2)
chr3_-_113495763 0.700 NM_183061
 SLC9A10
solute carrier family 9, member 10
chr10_+_49279647 0.699 NM_002750
NM_139046
NM_139047
NM_139049
 MAPK8



mitogen-activated protein kinase 8




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
6.64 2.87e-02 GO:0060338 regulation of type I interferon-mediated signaling pathway
3.69 7.19e-15 GO:0007608 sensory perception of smell
3.53 4.57e-15 GO:0007606 sensory perception of chemical stimulus
3.42 8.29e-03 GO:0007156 homophilic cell adhesion
2.89 2.04e-16 GO:0007600 sensory perception
2.23 8.21e-13 GO:0050877 neurological system process
2.23 7.61e-03 GO:0050776 regulation of immune response
2.13 5.43e-05 GO:0006955 immune response
2.09 2.66e-13 GO:0003008 system process
1.70 4.70e-03 GO:0002376 immune system process
1.35 1.74e-05 GO:0032501 multicellular organismal process
1.27 1.12e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.89 1.03e-06 GO:0005887 integral to plasma membrane
1.88 1.19e-06 GO:0031226 intrinsic to plasma membrane
1.85 1.47e-03 GO:0005615 extracellular space
1.83 6.15e-11 GO:0005576 extracellular region
1.79 3.60e-04 GO:0044421 extracellular region part
1.63 1.69e-15 GO:0005886 plasma membrane
1.61 5.54e-15 GO:0071944 cell periphery
1.55 5.54e-05 GO:0044459 plasma membrane part
1.50 9.63e-15 GO:0031224 intrinsic to membrane
1.49 5.69e-14 GO:0016021 integral to membrane
1.40 3.10e-12 GO:0044425 membrane part
1.24 1.05e-05 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.87 1.79e-16 GO:0004984 olfactory receptor activity
3.13 1.77e-04 GO:0005125 cytokine activity
2.96 2.15e-03 GO:0005126 cytokine receptor binding
2.88 1.32e-17 GO:0004930 G-protein coupled receptor activity
2.57 2.58e-20 GO:0004888 transmembrane receptor activity
2.31 3.10e-20 GO:0004872 receptor activity
2.03 2.34e-16 GO:0004871 signal transducer activity
2.03 2.34e-16 GO:0060089 molecular transducer activity
1.91 5.79e-03 GO:0005509 calcium ion binding