Motif ID: GTF2A1,2.p2

Z-value: 2.013


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A1chr14_-_80757327-0.514.6e-02Click!
GTF2A2chr15_-_57736828-0.312.4e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_129823667 4.962 NM_139055
 ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr7_-_41709191 3.787 NM_002192
 INHBA
inhibin, beta A
chr8_+_37672427 3.563 NM_025069
 ZNF703
zinc finger protein 703
chr15_-_73792234 3.197 NM_001897
 CSPG4
chondroitin sulfate proteoglycan 4
chr15_-_73792150 3.082 CSPG4
chondroitin sulfate proteoglycan 4
chr2_+_27154938 2.862 NM_007046
 EMILIN1
elastin microfibril interfacer 1
chr2_+_242146791 2.542 NM_032515
 BOK
BCL2-related ovarian killer
chr9_+_35528890 2.526 RUSC2
RUN and SH3 domain containing 2
chr17_-_77602493 2.506 RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_+_141879555 2.456 NM_152616
 TRIM42
tripartite motif containing 42
chrX_-_139414890 2.387 NM_005634
 SOX3
SRY (sex determining region Y)-box 3
chr2_+_27155197 2.249 EMILIN1
elastin microfibril interfacer 1
chr12_+_13240868 2.246 NM_001423
 EMP1
epithelial membrane protein 1
chr12_-_7136147 2.204 NM_001733
 C1R
complement component 1, r subcomponent
chr12_-_7136189 2.164 C1R
complement component 1, r subcomponent
chr17_+_45488330 2.162 NM_002204
NM_005501
 ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr1_-_245988330 2.156 NM_012353
 OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr16_+_54072969 2.139 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_+_28469275 2.109 NM_005253
 FOSL2
FOS-like antigen 2
chr5_+_60663842 2.049 NM_020928
 ZSWIM6
zinc finger, SWIM-type containing 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.83 1.30e-02 GO:0002576 platelet degranulation
2.29 1.21e-02 GO:0034330 cell junction organization
1.92 1.49e-02 GO:0001568 blood vessel development
1.90 1.19e-02 GO:0040012 regulation of locomotion
1.90 3.32e-02 GO:0030334 regulation of cell migration
1.87 4.65e-02 GO:2000145 regulation of cell motility
1.86 2.60e-02 GO:0001944 vasculature development
1.85 1.64e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.85 4.56e-02 GO:0061061 muscle structure development
1.70 8.07e-03 GO:0072358 cardiovascular system development
1.70 8.07e-03 GO:0072359 circulatory system development
1.60 4.72e-02 GO:0023056 positive regulation of signaling
1.51 2.32e-02 GO:0007155 cell adhesion
1.51 2.32e-02 GO:0022610 biological adhesion
1.46 4.72e-02 GO:0009888 tissue development
1.43 5.11e-04 GO:0009966 regulation of signal transduction
1.38 1.12e-03 GO:0023051 regulation of signaling
1.37 4.09e-04 GO:0048583 regulation of response to stimulus
1.36 1.18e-02 GO:0009653 anatomical structure morphogenesis
1.32 4.38e-03 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.19 3.92e-03 GO:0031983 vesicle lumen
3.12 1.81e-02 GO:0031093 platelet alpha granule lumen
3.05 2.39e-02 GO:0034774 secretory granule lumen
3.03 4.89e-03 GO:0031091 platelet alpha granule
2.93 4.04e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.89 3.06e-02 GO:0030141 stored secretory granule
1.79 8.50e-04 GO:0031012 extracellular matrix
1.79 4.38e-03 GO:0005578 proteinaceous extracellular matrix
1.63 4.00e-08 GO:0044421 extracellular region part
1.56 4.11e-03 GO:0030054 cell junction
1.54 3.26e-04 GO:0005615 extracellular space
1.43 1.83e-08 GO:0005576 extracellular region
1.31 3.36e-04 GO:0044459 plasma membrane part
1.17 8.55e-03 GO:0005886 plasma membrane
1.17 1.82e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.52 2.60e-02 GO:0005198 structural molecule activity