Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.466


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78520634-0.766.3e-04Click!
MYCchr8_+_1288176580.712.1e-03Click!
BHLHE40chr3_+_49960960.581.8e-02Click!
ARNTchr1_-_149115686-0.411.1e-01Click!
MAXchr14_-_64638809-0.302.5e-01Click!
USF1chr1_-_159282376-0.155.9e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_73636362 2.335 TMC6
transmembrane channel-like 6
chr12_-_56432385 1.963 NM_000075
CDK4
cyclin-dependent kinase 4
chr8_+_142471290 1.713


chr1_+_11788827 1.696 CLCN6
chloride channel 6
chr17_-_53764867 1.667


chrX_+_100549869 1.467 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_+_100549861 1.395 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_-_73636386 1.361 NM_001127198
TMC6
transmembrane channel-like 6
chr1_-_152797707 1.329 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chrX_+_100549839 1.293 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr16_+_2510323 1.286 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chrX_+_100549885 1.281 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_-_100490329 1.270 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_-_85457469 1.269 PICALM
phosphatidylinositol binding clathrin assembly protein
chr3_-_4483952 1.265 SUMF1
sulfatase modifying factor 1
chr1_+_20385164 1.228 NM_152376
UBXN10
UBX domain protein 10
chr1_-_26105954 1.227 NM_203399
STMN1
stathmin 1
chr11_-_85457753 1.215 NM_001008660
NM_007166
PICALM

phosphatidylinositol binding clathrin assembly protein

chrX_+_102356659 1.213 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr1_-_26105477 1.196 NM_001145454
NM_005563
STMN1

stathmin 1

chr11_-_85457736 1.156 PICALM
phosphatidylinositol binding clathrin assembly protein
chr6_-_33493792 1.144 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_-_11788666 1.141 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_100549561 1.138 NM_000169
GLA
galactosidase, alpha
chr16_+_1341937 1.095 GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr3_-_4483928 1.054 SUMF1
sulfatase modifying factor 1
chr3_-_4483955 1.036 NM_001164674
NM_001164675
NM_182760
SUMF1


sulfatase modifying factor 1


chr4_-_100069265 1.017 NM_001130678
EIF4E
eukaryotic translation initiation factor 4E
chrX_+_117992603 1.016 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_-_224178600 1.015 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr1_-_224253678 0.993 NM_152608
C1orf55
chromosome 1 open reading frame 55
chr1_+_11788793 0.989 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chrX_+_134482212 0.968 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_-_56432292 0.968 CDK4
cyclin-dependent kinase 4
chr1_+_111544469 0.959


chr1_-_113300351 0.945 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr9_-_130749604 0.917 NM_014908
DOLK
dolichol kinase
chr16_-_4837266 0.914 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr1_+_45250475 0.912 UROD
uroporphyrinogen decarboxylase
chr12_-_56432377 0.909 CDK4
cyclin-dependent kinase 4
chr1_+_10015736 0.907 UBE4B
ubiquitination factor E4B (UFD2 homolog, yeast)
chr1_-_224253650 0.884 C1orf55
chromosome 1 open reading frame 55
chr6_+_87921980 0.876 NM_015021
ZNF292
zinc finger protein 292
chrX_+_130985316 0.875 NM_001042452
MST4
serine/threonine protein kinase MST4
chr6_-_31871394 0.870 VARS
valyl-tRNA synthetase
chr1_-_224253610 0.868 C1orf55
chromosome 1 open reading frame 55
chr1_-_113300138 0.861 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr1_+_29113589 0.859 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_224253642 0.858 C1orf55
chromosome 1 open reading frame 55
chr12_+_115660468 0.855 NM_001109903
NM_032814
RNFT2

ring finger protein, transmembrane 2

chr13_+_41744255 0.854 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr8_-_54918099 0.851 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr9_+_130749791 0.841 NM_015354
NUP188
nucleoporin 188kDa
chr1_+_40399642 0.827 RLF
rearranged L-myc fusion
chr4_-_100069303 0.818 EIF4E
eukaryotic translation initiation factor 4E
chrX_+_117992623 0.815 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr6_+_160310118 0.815 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr1_+_40399618 0.810 NM_012421
RLF
rearranged L-myc fusion
chr5_-_131160614 0.807 NM_001008738
NM_133372
FNIP1

folliculin interacting protein 1

chr22_+_38720881 0.806 NM_138435
FAM83F
family with sequence similarity 83, member F
chr4_-_103485600 0.804 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr1_-_35957030 0.801 C1orf216
chromosome 1 open reading frame 216
chr7_+_154720547 0.795 INSIG1
insulin induced gene 1
chr8_+_95722448 0.793 ESRP1
epithelial splicing regulatory protein 1
chr8_+_109525050 0.786 TTC35
tetratricopeptide repeat domain 35
chr1_+_29086206 0.776 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_-_52709975 0.771 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_45250503 0.763 UROD
uroporphyrinogen decarboxylase
chr16_-_66827449 0.763 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr7_+_101860958 0.763 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr1_+_26609819 0.759 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr8_+_38153223 0.747 NM_004874
BAG4
BCL2-associated athanogene 4
chr2_+_198072965 0.743 NM_002157
HSPE1
heat shock 10kDa protein 1 (chaperonin 10)
chr1_-_115060904 0.739 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr8_-_54918389 0.739 NM_015941
NM_213619
ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

chr1_-_35956979 0.731 C1orf216
chromosome 1 open reading frame 216
chr9_+_130749812 0.730 NUP188
nucleoporin 188kDa
chr2_-_10505902 0.727 NM_002539
ODC1
ornithine decarboxylase 1
chr7_+_154720416 0.727 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr6_-_33493640 0.719 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_54149941 0.719 BAX
BCL2-associated X protein
chr7_+_101861007 0.718 ORAI2
ORAI calcium release-activated calcium modulator 2
chr8_+_109525010 0.715 NM_014673
TTC35
tetratricopeptide repeat domain 35
chr18_+_30810889 0.714 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr11_-_18300246 0.712 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr5_-_131160541 0.705 FNIP1
folliculin interacting protein 1
chr1_+_26609893 0.698 LIN28A
lin-28 homolog A (C. elegans)
chr1_+_29086156 0.693 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr1_+_11788889 0.690 CLCN6
chloride channel 6
chr17_+_54997667 0.681 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr1_-_152459697 0.679 NM_001098616
NM_015449
NM_138740
C1orf43


chromosome 1 open reading frame 43


chrX_-_100490612 0.676 NM_004085
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr1_+_205293217 0.674 NM_001018053
NM_006212
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr1_-_11788550 0.674 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_-_35273947 0.671 NM_012481
NM_183228
NM_183229
NM_183230
NM_183231
NM_183232
IKZF3





IKAROS family zinc finger 3 (Aiolos)





chr16_+_1341900 0.671 NM_032520
GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr3_+_4996096 0.668 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr13_-_45640679 0.666 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_10015577 0.662 NM_001105562
NM_006048
UBE4B

ubiquitination factor E4B (UFD2 homolog, yeast)

chrX_+_146870540 0.658 NM_152578
FMR1NB
fragile X mental retardation 1 neighbor
chr11_+_66915997 0.656 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr3_-_20202622 0.655 NM_001012409
NM_001012410
NM_001012411
NM_001012412
NM_001012413
NM_138484
SGOL1





shugoshin-like 1 (S. pombe)





chrX_+_130984912 0.650 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr8_-_54918325 0.649 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chrX_+_49084499 0.638 NM_012196
NM_001472
NM_001127200
NM_001098407
NM_001127212
GAGE8
GAGE1
GAGE2C
GAGE2E
GAGE12J
GAGE2D
GAGE2A
G antigen 8
G antigen 1
G antigen 2C
G antigen 2E
G antigen 12J
G antigen 2D
G antigen 2A
chr1_-_26105230 0.637 NM_203401
STMN1
stathmin 1
chr22_-_19543099 0.633 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr5_+_133735004 0.632 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr3_+_50629604 0.629 NM_004635
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr6_-_43305156 0.624 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr10_+_70553936 0.622 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chrX_-_102452461 0.618 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr1_-_52936611 0.615 NM_023077
C1orf163
chromosome 1 open reading frame 163
chr19_+_6415259 0.612 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr8_-_126173203 0.611 KIAA0196
KIAA0196
chr8_+_98725604 0.609 MTDH
metadherin
chr17_+_43373887 0.603 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr3_+_4996141 0.603 BHLHE40
basic helix-loop-helix family, member e40
chr7_+_106472243 0.603 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chrX_+_134482387 0.601 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr10_-_88116181 0.600 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr1_+_44213200 0.598 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr9_-_125070675 0.595 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr9_-_126573349 0.591 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr1_-_52936573 0.590 C1orf163
chromosome 1 open reading frame 163
chr6_-_31871452 0.589 VARS
valyl-tRNA synthetase
chr19_+_37528340 0.588 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chr1_-_40335451 0.588 PPT1
palmitoyl-protein thioesterase 1
chr12_+_110935618 0.586 ERP29
endoplasmic reticulum protein 29
chr1_-_40335496 0.581 PPT1
palmitoyl-protein thioesterase 1
chrX_-_107866262 0.578 NM_003604
IRS4
insulin receptor substrate 4
chr9_-_139129015 0.578 NM_013379
DPP7
dipeptidyl-peptidase 7
chr7_+_116380590 0.576 NM_018412
NM_021908
ST7

suppression of tumorigenicity 7

chr4_+_101090648 0.575 LOC256880
hypothetical LOC256880
chrX_+_16714452 0.574 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr13_+_26896614 0.571 NM_002097
GTF3A
general transcription factor IIIA
chr18_+_9126742 0.571 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr9_+_37110506 0.570 ZCCHC7
zinc finger, CCHC domain containing 7
chr4_-_103485419 0.569 NM_001135147
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr3_+_160002582 0.569 MFSD1
major facilitator superfamily domain containing 1
chr1_-_40335504 0.568 PPT1
palmitoyl-protein thioesterase 1
chr1_-_224178486 0.567 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr12_+_92488932 0.566 SOCS2
suppressor of cytokine signaling 2
chr7_+_50314801 0.566 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_-_224178475 0.565 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr1_-_224178606 0.565 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chrX_-_118583346 0.562 NM_001170569
CXorf56
chromosome X open reading frame 56
chr20_+_60744268 0.561 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr5_+_154115046 0.560 LARP1
La ribonucleoprotein domain family, member 1
chr17_+_44325127 0.560 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_+_45250388 0.559 NM_000374
UROD
uroporphyrinogen decarboxylase
chr15_-_81113676 0.557 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr8_-_126173055 0.556 KIAA0196
KIAA0196
chr1_-_224178553 0.555 NM_013328
PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr9_+_37110468 0.554 NM_032226
ZCCHC7
zinc finger, CCHC domain containing 7
chr22_-_17799177 0.554 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_-_115060857 0.554 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_-_224178412 0.553 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr12_-_47749996 0.545 NM_144593
RHEBL1
Ras homolog enriched in brain like 1
chr5_+_89890366 0.544 NM_032119
GPR98
G protein-coupled receptor 98
chr16_+_22124870 0.543 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr9_-_125070613 0.540 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr2_-_10505724 0.540 ODC1
ornithine decarboxylase 1
chr1_-_28432060 0.538 DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr1_-_227828339 0.536 TAF5L
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr10_+_22645304 0.536 NM_012071
COMMD3-BMI1
COMMD3
COMMD3-BMI1 read-through transcript
COMM domain containing 3
chr6_-_28999388 0.535 TRIM27
tripartite motif containing 27
chr2_+_177785667 0.529 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr15_-_48766213 0.527 TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr12_+_51686512 0.526 EIF4B
eukaryotic translation initiation factor 4B
chr18_+_9698187 0.525 NM_006868
RAB31
RAB31, member RAS oncogene family
chr5_+_133734768 0.521 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr1_-_52936602 0.516 C1orf163
chromosome 1 open reading frame 163
chr3_-_198509276 0.515 DLG1
discs, large homolog 1 (Drosophila)
chr6_-_28999621 0.513 TRIM27
tripartite motif containing 27
chr6_-_44333002 0.513 NM_178148
SLC35B2
solute carrier family 35, member B2
chr11_-_47620590 0.511 NM_014342
MTCH2
mitochondrial carrier homolog 2 (C. elegans)
chr19_+_55614006 0.510 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr9_-_130124317 0.510 NM_015679
TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr1_+_234625338 0.508 NM_080738
EDARADD
EDAR-associated death domain
chr7_-_8268206 0.507 NM_022307
ICA1
islet cell autoantigen 1, 69kDa
chr19_-_242335 0.505 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr10_-_32257693 0.505 ARHGAP12
Rho GTPase activating protein 12
chr7_-_8268666 0.504 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr22_-_17799215 0.504 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr4_-_56996400 0.500 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr8_+_142501188 0.500 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr5_-_131160608 0.497 FNIP1
folliculin interacting protein 1
chr2_-_10506033 0.494 ODC1
ornithine decarboxylase 1
chr1_-_165112093 0.492 TADA1
transcriptional adaptor 1
chr14_-_90953883 0.491 NM_001080414
CCDC88C
coiled-coil domain containing 88C
chr20_+_60744231 0.491 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr12_+_28234657 0.489


chr11_+_107384819 0.488 CUL5
cullin 5
chrX_-_118583401 0.488 NM_001170570
NM_022101
CXorf56

chromosome X open reading frame 56

chr4_-_101090505 0.488 NM_002106
H2AFZ
H2A histone family, member Z
chr12_+_49185035 0.487 DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr8_-_126173189 0.486 KIAA0196
KIAA0196
chr8_+_104496788 0.485 DCAF13
DDB1 and CUL4 associated factor 13
chr1_+_44213229 0.485 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 1.20e-17 GO:0044237 cellular metabolic process
1.49 9.98e-15 GO:0034641 cellular nitrogen compound metabolic process
1.26 2.70e-14 GO:0008152 metabolic process
1.53 3.06e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 1.37e-13 GO:0006807 nitrogen compound metabolic process
1.28 2.74e-13 GO:0044238 primary metabolic process
1.37 2.85e-13 GO:0044260 cellular macromolecule metabolic process
1.56 5.34e-12 GO:0090304 nucleic acid metabolic process
1.60 1.95e-10 GO:0016070 RNA metabolic process
1.56 2.00e-09 GO:0010467 gene expression
1.29 4.79e-09 GO:0043170 macromolecule metabolic process
1.94 5.35e-08 GO:0006396 RNA processing
1.43 1.78e-07 GO:0044249 cellular biosynthetic process
1.41 3.58e-07 GO:0009058 biosynthetic process
1.12 4.40e-07 GO:0009987 cellular process
1.36 4.31e-05 GO:0044267 cellular protein metabolic process
1.66 8.65e-05 GO:0055085 transmembrane transport
1.42 3.29e-04 GO:0034645 cellular macromolecule biosynthetic process
1.42 5.08e-04 GO:0009059 macromolecule biosynthetic process
2.05 5.84e-04 GO:0006412 translation
2.30 1.18e-03 GO:0022613 ribonucleoprotein complex biogenesis
2.65 1.48e-03 GO:0042254 ribosome biogenesis
2.08 1.74e-03 GO:0034660 ncRNA metabolic process
1.87 3.15e-03 GO:0006397 mRNA processing
1.37 3.65e-03 GO:0044281 small molecule metabolic process
1.58 3.74e-03 GO:0046907 intracellular transport
2.13 3.96e-03 GO:0051186 cofactor metabolic process
2.19 4.81e-03 GO:0071843 cellular component biogenesis at cellular level
1.41 6.12e-03 GO:0009056 catabolic process
2.19 6.38e-03 GO:0000375 RNA splicing, via transesterification reactions
1.70 7.31e-03 GO:0016071 mRNA metabolic process
2.25 7.47e-03 GO:0051169 nuclear transport
1.70 8.04e-03 GO:0044265 cellular macromolecule catabolic process
1.45 8.27e-03 GO:0044248 cellular catabolic process
2.45 8.62e-03 GO:0019058 viral infectious cycle
1.64 9.54e-03 GO:0009057 macromolecule catabolic process
2.22 1.51e-02 GO:0006913 nucleocytoplasmic transport
2.36 1.91e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.13 2.16e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.13 2.16e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.61 2.53e-02 GO:0006414 translational elongation
2.13 2.87e-02 GO:0034470 ncRNA processing
2.18 3.00e-02 GO:0006732 coenzyme metabolic process
1.80 3.03e-02 GO:0030163 protein catabolic process
2.24 3.06e-02 GO:0022415 viral reproductive process
1.25 3.19e-02 GO:0006810 transport
1.24 3.32e-02 GO:0019538 protein metabolic process
1.87 4.06e-02 GO:0008380 RNA splicing
2.38 4.40e-02 GO:0006403 RNA localization
1.24 4.54e-02 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.80e-23 GO:0044424 intracellular part
1.17 1.14e-21 GO:0005622 intracellular
1.25 3.77e-21 GO:0043227 membrane-bounded organelle
1.25 4.14e-21 GO:0043231 intracellular membrane-bounded organelle
1.20 5.61e-17 GO:0043229 intracellular organelle
1.20 6.96e-17 GO:0043226 organelle
1.23 4.48e-16 GO:0005737 cytoplasm
1.31 5.93e-14 GO:0044446 intracellular organelle part
1.30 1.16e-13 GO:0044422 organelle part
1.54 1.44e-13 GO:0031974 membrane-enclosed lumen
1.55 1.74e-13 GO:0070013 intracellular organelle lumen
1.30 5.65e-13 GO:0005634 nucleus
1.55 7.23e-13 GO:0044428 nuclear part
1.53 8.51e-13 GO:0043233 organelle lumen
1.57 4.10e-11 GO:0031981 nuclear lumen
1.26 4.89e-11 GO:0044444 cytoplasmic part
2.09 2.06e-09 GO:0005730 nucleolus
2.07 3.20e-09 GO:0030529 ribonucleoprotein complex
1.44 2.37e-07 GO:0005829 cytosol
1.56 4.54e-07 GO:0005654 nucleoplasm
1.67 4.20e-05 GO:0031967 organelle envelope
1.66 5.52e-05 GO:0031975 envelope
1.26 8.76e-05 GO:0032991 macromolecular complex
1.64 1.34e-04 GO:0044451 nucleoplasm part
2.20 1.52e-04 GO:0016604 nuclear body
5.98 4.64e-04 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.32 6.99e-04 GO:0031090 organelle membrane
1.57 3.53e-03 GO:0044429 mitochondrial part
1.82 3.91e-03 GO:0019866 organelle inner membrane
1.85 4.14e-03 GO:0005773 vacuole
2.66 7.15e-03 GO:0042470 melanosome
2.66 7.15e-03 GO:0048770 pigment granule
1.67 8.86e-03 GO:0031966 mitochondrial membrane
1.65 1.06e-02 GO:0005740 mitochondrial envelope
1.35 2.35e-02 GO:0005739 mitochondrion
3.26 4.28e-02 GO:0016469 proton-transporting two-sector ATPase complex
1.82 4.54e-02 GO:0010008 endosome membrane
2.94 4.74e-02 GO:0031901 early endosome membrane
1.73 4.92e-02 GO:0005743 mitochondrial inner membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.02 2.50e-14 GO:0003723 RNA binding
1.20 1.03e-08 GO:0005515 protein binding
1.93 6.27e-06 GO:0016874 ligase activity
2.07 7.98e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.08 3.16e-04 GO:0005488 binding
1.26 4.01e-04 GO:0003676 nucleic acid binding
2.01 1.15e-03 GO:0016881 acid-amino acid ligase activity
4.62 2.06e-03 GO:0003727 single-stranded RNA binding
1.30 2.70e-03 GO:0000166 nucleotide binding
1.17 4.48e-03 GO:0003824 catalytic activity
8.08 1.05e-02 GO:0030515 snoRNA binding
1.97 1.14e-02 GO:0019787 small conjugating protein ligase activity