Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.466


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_78520634-0.766.3e-04Click!
MYCchr8_+_1288176580.712.1e-03Click!
BHLHE40chr3_+_49960960.581.8e-02Click!
ARNTchr1_-_149115686-0.411.1e-01Click!
MAXchr14_-_64638809-0.302.5e-01Click!
USF1chr1_-_159282376-0.155.9e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_73636362 2.335 TMC6
transmembrane channel-like 6
chr12_-_56432385 1.963 NM_000075
CDK4
cyclin-dependent kinase 4
chr8_+_142471290 1.713


chr1_+_11788827 1.696 CLCN6
chloride channel 6
chr17_-_53764867 1.667


chrX_+_100549869 1.467 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_+_100549861 1.395 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr17_-_73636386 1.361 NM_001127198
TMC6
transmembrane channel-like 6
chr1_-_152797707 1.329 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chrX_+_100549839 1.293 NM_001032393
NM_019597
HNRNPH2

heterogeneous nuclear ribonucleoprotein H2 (H')

chr16_+_2510323 1.286 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chrX_+_100549885 1.281 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_-_100490329 1.270 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr11_-_85457469 1.269 PICALM
phosphatidylinositol binding clathrin assembly protein
chr3_-_4483952 1.265 SUMF1
sulfatase modifying factor 1
chr1_+_20385164 1.228 NM_152376
UBXN10
UBX domain protein 10
chr1_-_26105954 1.227 NM_203399
STMN1
stathmin 1
chr11_-_85457753 1.215 NM_001008660
NM_007166
PICALM

phosphatidylinositol binding clathrin assembly protein

chrX_+_102356659 1.213 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr1_-_26105477 1.196 NM_001145454
NM_005563
STMN1

stathmin 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 50 entries
enrichment   p-value GO term description
2.65 1.48e-03 GO:0042254 ribosome biogenesis
2.61 2.53e-02 GO:0006414 translational elongation
2.45 8.62e-03 GO:0019058 viral infectious cycle
2.38 4.40e-02 GO:0006403 RNA localization
2.36 1.91e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.30 1.18e-03 GO:0022613 ribonucleoprotein complex biogenesis
2.25 7.47e-03 GO:0051169 nuclear transport
2.24 3.06e-02 GO:0022415 viral reproductive process
2.22 1.51e-02 GO:0006913 nucleocytoplasmic transport
2.19 4.81e-03 GO:0071843 cellular component biogenesis at cellular level
2.19 6.38e-03 GO:0000375 RNA splicing, via transesterification reactions
2.18 3.00e-02 GO:0006732 coenzyme metabolic process
2.13 3.96e-03 GO:0051186 cofactor metabolic process
2.13 2.16e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.13 2.16e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
2.13 2.87e-02 GO:0034470 ncRNA processing
2.08 1.74e-03 GO:0034660 ncRNA metabolic process
2.05 5.84e-04 GO:0006412 translation
1.94 5.35e-08 GO:0006396 RNA processing
1.87 3.15e-03 GO:0006397 mRNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
5.98 4.64e-04 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
3.26 4.28e-02 GO:0016469 proton-transporting two-sector ATPase complex
2.94 4.74e-02 GO:0031901 early endosome membrane
2.66 7.15e-03 GO:0042470 melanosome
2.66 7.15e-03 GO:0048770 pigment granule
2.20 1.52e-04 GO:0016604 nuclear body
2.09 2.06e-09 GO:0005730 nucleolus
2.07 3.20e-09 GO:0030529 ribonucleoprotein complex
1.85 4.14e-03 GO:0005773 vacuole
1.82 3.91e-03 GO:0019866 organelle inner membrane
1.82 4.54e-02 GO:0010008 endosome membrane
1.73 4.92e-02 GO:0005743 mitochondrial inner membrane
1.67 4.20e-05 GO:0031967 organelle envelope
1.67 8.86e-03 GO:0031966 mitochondrial membrane
1.66 5.52e-05 GO:0031975 envelope
1.65 1.06e-02 GO:0005740 mitochondrial envelope
1.64 1.34e-04 GO:0044451 nucleoplasm part
1.57 4.10e-11 GO:0031981 nuclear lumen
1.57 3.53e-03 GO:0044429 mitochondrial part
1.56 4.54e-07 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
8.08 1.05e-02 GO:0030515 snoRNA binding
4.62 2.06e-03 GO:0003727 single-stranded RNA binding
2.07 7.98e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.02 2.50e-14 GO:0003723 RNA binding
2.01 1.15e-03 GO:0016881 acid-amino acid ligase activity
1.97 1.14e-02 GO:0019787 small conjugating protein ligase activity
1.93 6.27e-06 GO:0016874 ligase activity
1.30 2.70e-03 GO:0000166 nucleotide binding
1.26 4.01e-04 GO:0003676 nucleic acid binding
1.20 1.03e-08 GO:0005515 protein binding
1.17 4.48e-03 GO:0003824 catalytic activity
1.08 3.16e-04 GO:0005488 binding