Motif ID: BPTF.p2

Z-value: 1.638


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_632527040.775.3e-04Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_39874921 2.261 NM_004310
RHOH
ras homolog gene family, member H
chr19_+_52504914 1.328 NM_001736
C5AR1
complement component 5a receptor 1
chr2_-_225073357 1.261 CUL3
cullin 3
chrX_-_71709622 1.256 NM_001166418
NM_001166419
NM_001166420
NM_001166422
NM_001166448
NM_018486
HDAC8





histone deacetylase 8





chr18_+_27425727 1.223 NM_000371
TTR
transthyretin
chr3_+_188222337 1.206 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chrX_+_119176494 1.190 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr4_-_40212670 1.145 NM_019027
RBM47
RNA binding motif protein 47
chr12_+_7809078 1.136 NM_001145465
NANOGNB
NANOG neighbor homeobox
chr1_-_12599934 1.120 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr2_+_215884923 1.095 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr21_+_29322100 1.008 USP16
ubiquitin specific peptidase 16
chr17_-_59818033 0.971 PECAM1
platelet/endothelial cell adhesion molecule
chr13_-_45654327 0.958 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_45654292 0.958 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_10387412 0.956 ATF7IP2
activating transcription factor 7 interacting protein 2
chr4_-_88531353 0.937 NM_016245
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr9_+_6710862 0.933 NM_001146696
KDM4C
lysine (K)-specific demethylase 4C
chr5_-_42847716 0.925 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr10_-_98311813 0.918 TM9SF3
transmembrane 9 superfamily member 3
chrX_-_23955223 0.906 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr2_+_215885053 0.898 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_-_74390861 0.884 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr3_-_33734544 0.865 CLASP2
cytoplasmic linker associated protein 2
chr13_-_45654296 0.863 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_52037186 0.854 RBL2
retinoblastoma-like 2 (p130)
chr10_-_69836912 0.847 NM_017987
NM_001042417
RUFY2

RUN and FYVE domain containing 2

chr3_-_110539023 0.835 DPPA4
developmental pluripotency associated 4
chrX_-_118610880 0.832 NM_001173488
NKRF
NFKB repressing factor
chr15_+_53398424 0.827 NM_004855
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr1_+_111571803 0.819 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr2_+_24016771 0.810 NM_181713
UBXN2A
UBX domain protein 2A
chr12_+_111829191 0.797 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr17_-_1195096 0.786 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr16_+_3499894 0.781 NM_024793
CLUAP1
clusterin associated protein 1
chr15_+_53398697 0.761 PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr9_+_94749421 0.742 NM_001083536
FGD3
FYVE, RhoGEF and PH domain containing 3
chr16_-_73258276 0.733 NM_018124
RFWD3
ring finger and WD repeat domain 3
chr19_-_58016696 0.728 NM_006969
ZNF28
zinc finger protein 28
chr3_-_126797057 0.724 NM_022776
OSBPL11
oxysterol binding protein-like 11
chr13_-_40138607 0.715 NM_002015
FOXO1
forkhead box O1
chr7_+_64476167 0.714 NM_007139
NM_152626
ZNF92

zinc finger protein 92

chr6_+_64414389 0.714 NM_015153
PHF3
PHD finger protein 3
chr17_-_64823368 0.708 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr7_+_64476226 0.702 ZNF92
zinc finger protein 92
chr1_-_158948176 0.698 NM_001778
CD48
CD48 molecule
chr2_-_171631728 0.682 NM_001136555
TLK1
tousled-like kinase 1
chr19_+_8023887 0.678 NM_005624
CCL25
chemokine (C-C motif) ligand 25
chr5_+_139008091 0.674 CXXC5
CXXC finger protein 5
chr18_+_27925923 0.671 RNF138
ring finger protein 138
chr12_-_55432348 0.661 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr17_-_37275142 0.659 NM_018143
KLHL11
kelch-like 11 (Drosophila)
chr6_-_24466258 0.657 NM_016356
DCDC2
doublecortin domain containing 2
chr20_-_41788975 0.636 NM_001008901
NM_176791
GTSF1L

gametocyte specific factor 1-like

chr15_-_20638283 0.635 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr3_-_195670256 0.635 NM_024524
ATP13A3
ATPase type 13A3
chr15_-_70385709 0.634 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr6_-_31668476 0.631 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr7_-_143587653 0.628 NM_001005328
OR2A7
OR2A4
olfactory receptor, family 2, subfamily A, member 7
olfactory receptor, family 2, subfamily A, member 4
chr11_+_107497462 0.627 NM_000019
ACAT1
acetyl-CoA acetyltransferase 1
chr2_+_160277273 0.626 MARCH7
membrane-associated ring finger (C3HC4) 7
chr4_-_88531245 0.625 HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chrX_+_23982992 0.624 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr12_-_122272346 0.610 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr4_-_187114863 0.608 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr18_-_53440005 0.603 NARS
asparaginyl-tRNA synthetase
chr16_-_73258248 0.602 RFWD3
ring finger and WD repeat domain 3
chr18_+_27925815 0.592 NM_016271
RNF138
ring finger protein 138
chr12_-_99060771 0.591 NM_001006947
NM_015054
UHRF1BP1L

UHRF1 binding protein 1-like

chrX_+_47999740 0.589 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr17_+_50697319 0.586 NM_002126
HLF
hepatic leukemia factor
chr3_-_79899748 0.584 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr13_+_49487390 0.583 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chrX_-_102829621 0.582 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr20_-_47307554 0.581 ZNFX1
zinc finger, NFX1-type containing 1
chr5_+_61910318 0.579 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_-_15914485 0.579 NCOR1
nuclear receptor corepressor 1
chr20_+_56903595 0.576 GNAS
GNAS complex locus
chr15_+_39363442 0.575 LOC729082
hypothetical LOC729082
chr15_-_32398220 0.574 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_-_152847256 0.570 ADAR
adenosine deaminase, RNA-specific
chr20_-_47963682 0.567 NM_001135773
SPATA2
spermatogenesis associated 2
chr4_-_15694764 0.565 PROM1
prominin 1
chr14_+_101345878 0.565 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr7_-_92057597 0.559 NM_001040057
NM_152789
FAM133B

family with sequence similarity 133, member B

chr10_+_86078136 0.557 NM_018999
FAM190B
family with sequence similarity 190, member B
chr9_+_127002630 0.556 NM_001174152
NM_001174153
RABEPK

Rab9 effector protein with kelch motifs

chr3_+_19963534 0.555 NM_004162
RAB5A
RAB5A, member RAS oncogene family
chrX_+_23982981 0.555 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr15_-_60139857 0.552 NM_001018088
NM_017684
NM_018080
NM_020821
VPS13C



vacuolar protein sorting 13 homolog C (S. cerevisiae)



chrX_-_80344096 0.550 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chrX_-_19443299 0.549 NM_001001671
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr1_+_26744893 0.548 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_+_42368540 0.547 VDAC3
voltage-dependent anion channel 3
chr22_+_17012841 0.547 USP18
ubiquitin specific peptidase 18
chr16_+_24648446 0.528 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr13_-_98757634 0.527 NM_004951
GPR183
G protein-coupled receptor 183
chr1_-_93418833 0.526 NM_001167830
NM_016040
TMED5

transmembrane emp24 protein transport domain containing 5

chr12_-_99060590 0.525 UHRF1BP1L
UHRF1 binding protein 1-like
chr22_+_35290271 0.522


chr10_-_32707549 0.521 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr8_-_37847095 0.521 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr1_+_46910086 0.521 NM_001145474
C1orf223
chromosome 1 open reading frame 223
chrX_-_76824726 0.517 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr3_-_161584137 0.517 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr2_+_201464884 0.514 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr6_+_42857540 0.509 KIAA0240
KIAA0240
chr10_-_93992982 0.504 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr15_-_74390846 0.503 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr15_+_57184568 0.503 NM_004701
CCNB2
cyclin B2
chr2_+_61243132 0.502 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr3_-_33734747 0.496 NM_015097
CLASP2
cytoplasmic linker associated protein 2
chr3_+_142175329 0.496 SLC25A36
solute carrier family 25, member 36
chr22_+_21079355 0.495


chr5_+_139856688 0.495 ANKHD1
ankyrin repeat and KH domain containing 1
chr22_+_38652555 0.494 GRAP2
GRB2-related adaptor protein 2
chr4_+_170817787 0.493 CLCN3
chloride channel 3
chr12_-_54607925 0.493 WIBG
within bgcn homolog (Drosophila)
chr16_-_73258218 0.489 RFWD3
ring finger and WD repeat domain 3
chr12_+_73219826 0.489


chr17_+_50697355 0.488 HLF
hepatic leukemia factor
chr12_-_93921586 0.486 NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr2_+_3600784 0.485 RPS7
ribosomal protein S7
chrX_+_41433169 0.484 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr9_+_5646582 0.484 NM_020829
KIAA1432
KIAA1432
chrX_-_12972641 0.484 NM_174901
FAM9C
family with sequence similarity 9, member C
chr3_-_52688768 0.483 NM_018165
NM_181042
PBRM1

polybromo 1

chr2_+_215885063 0.480 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_+_108769572 0.480 NM_144978
CCDC138
coiled-coil domain containing 138
chr4_+_53986759 0.479 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr11_-_47620590 0.479 NM_014342
MTCH2
mitochondrial carrier homolog 2 (C. elegans)
chr11_-_3759886 0.477 NUP98
nucleoporin 98kDa
chr10_+_82158186 0.477 NM_032333
C10orf58
chromosome 10 open reading frame 58
chr7_+_74962234 0.475 NM_001099435
SPDYE5
speedy homolog E5 (Xenopus laevis)
chrX_-_119486874 0.475 LAMP2
lysosomal-associated membrane protein 2
chr11_-_33847834 0.473 LMO2
LIM domain only 2 (rhombotin-like 1)
chr20_-_39199936 0.469


chr6_-_24491498 0.468 NM_001195610
DCDC2
doublecortin domain containing 2
chr11_-_77411933 0.467 NM_023930
KCTD14
potassium channel tetramerisation domain containing 14
chr16_+_28850760 0.467 NM_001178098
NM_001770
CD19

CD19 molecule

chr1_+_39569396 0.466 NM_033044
MACF1
microtubule-actin crosslinking factor 1
chr13_-_24395054 0.466 NM_018451
CENPJ
centromere protein J
chr2_-_44440358 0.465 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr6_+_109557199 0.463 NM_173830
CEP57L1
centrosomal protein 57kDa-like 1
chrX_-_19815370 0.460 SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_100979869 0.459 CCDC53
coiled-coil domain containing 53
chr17_-_34860840 0.455 NM_004774
MED1
mediator complex subunit 1
chr13_-_40735619 0.454 NM_004294
MTRF1
mitochondrial translational release factor 1
chr7_-_149960218 0.452 GIMAP6
GTPase, IMAP family member 6
chr17_+_34871214 0.451 NM_015083
NM_016507
CDK12

cyclin-dependent kinase 12

chr17_-_57295451 0.447 NM_032043
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr3_+_173240107 0.447 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr1_+_78017894 0.446 NM_198549
FAM73A
family with sequence similarity 73, member A
chr4_-_21308415 0.445 NM_001035003
KCNIP4
Kv channel interacting protein 4
chr21_-_39739528 0.443 LCA5L
Leber congenital amaurosis 5-like
chr5_-_77841686 0.442 LHFPL2
lipoma HMGIC fusion partner-like 2
chr20_+_56904042 0.442 GNAS
GNAS complex locus
chr15_-_76378957 0.441 NM_025234
WDR61
WD repeat domain 61
chr11_-_77026406 0.439 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr19_-_44014228 0.438 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr2_+_85658235 0.437 VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr1_-_218329773 0.437 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chrX_-_70243362 0.436 NM_001025265
CXorf65
chromosome X open reading frame 65
chr1_-_165789640 0.435 NM_003851
CREG1
cellular repressor of E1A-stimulated genes 1
chr2_-_232034638 0.435 NCL
nucleolin
chr13_-_24394913 0.434 CENPJ
centromere protein J
chr20_-_33580861 0.433 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr6_-_24827265 0.432 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr1_+_221955876 0.432 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr1_+_144595224 0.432 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr6_+_44295219 0.432 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr15_-_41904059 0.431 NM_005926
MFAP1
microfibrillar-associated protein 1
chr12_+_111375382 0.429 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr9_-_98580148 0.429 NM_014930
ZNF510
zinc finger protein 510
chr16_+_8714326 0.428 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr12_-_12182641 0.428 LRP6
low density lipoprotein receptor-related protein 6
chrX_+_24393264 0.427 NM_001142386
NM_005391
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr19_+_23737651 0.427 RPSAP58
ribosomal protein SA pseudogene 58
chr12_-_44919818 0.426 SLC38A1
solute carrier family 38, member 1
chr19_+_39402167 0.425 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr1_-_165789586 0.425 CREG1
cellular repressor of E1A-stimulated genes 1
chr10_-_29963847 0.425


chr15_-_74390797 0.424 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr18_-_53440012 0.423 NARS
asparaginyl-tRNA synthetase
chr5_-_32439067 0.423 ZFR
zinc finger RNA binding protein
chr16_-_57325633 0.422 NM_002080
GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr1_-_204852465 0.421 NM_006893
EIF2D
eukaryotic translation initiation factor 2D
chrX_-_15242589 0.420 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chrX_-_32083506 0.420 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr16_+_4485859 0.419 NM_001127205
HMOX2
heme oxygenase (decycling) 2
chr5_+_161427225 0.418 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr12_+_32723539 0.418 DNM1L
dynamin 1-like
chr6_+_44418374 0.418 NM_145026
SPATS1
spermatogenesis associated, serine-rich 1
chr11_+_120966280 0.417 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr6_-_149847718 0.416 ZC3H12D
zinc finger CCCH-type containing 12D
chr4_-_15694691 0.416 NM_001145847
NM_001145848
PROM1

prominin 1

chr14_+_38804226 0.415 NM_203354
CTAGE5
CTAGE family, member 5
chr13_+_77213295 0.415 NM_144595
SLAIN1
SLAIN motif family, member 1
chr1_-_165789630 0.415 CREG1
cellular repressor of E1A-stimulated genes 1
chr15_-_53398534 0.414



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 8.47e-08 GO:0044237 cellular metabolic process
1.19 3.05e-06 GO:0044260 cellular macromolecule metabolic process
1.13 3.38e-06 GO:0008152 metabolic process
1.31 1.86e-05 GO:0010467 gene expression
1.13 7.94e-05 GO:0044238 primary metabolic process
1.23 1.36e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 3.37e-04 GO:0016070 RNA metabolic process
1.20 3.39e-04 GO:0034641 cellular nitrogen compound metabolic process
1.25 5.37e-04 GO:0090304 nucleic acid metabolic process
1.19 6.85e-04 GO:0006807 nitrogen compound metabolic process
1.14 2.33e-03 GO:0043170 macromolecule metabolic process
1.41 3.58e-03 GO:0022402 cell cycle process
1.06 4.16e-03 GO:0009987 cellular process
1.44 4.49e-03 GO:0022403 cell cycle phase
1.48 4.81e-03 GO:0000278 mitotic cell cycle
1.35 5.72e-03 GO:0007049 cell cycle
2.27 1.26e-02 GO:0000236 mitotic prometaphase
1.56 1.55e-02 GO:0006397 mRNA processing
1.79 2.19e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.79 2.19e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.77 2.39e-02 GO:0000375 RNA splicing, via transesterification reactions
1.61 3.66e-02 GO:0008380 RNA splicing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 2.12e-16 GO:0043231 intracellular membrane-bounded organelle
1.15 2.53e-16 GO:0043227 membrane-bounded organelle
1.10 9.44e-16 GO:0005622 intracellular
1.11 1.73e-15 GO:0044424 intracellular part
1.22 2.43e-14 GO:0005634 nucleus
1.12 3.57e-12 GO:0043229 intracellular organelle
1.12 6.00e-12 GO:0043226 organelle
1.35 4.17e-10 GO:0044428 nuclear part
1.36 5.30e-09 GO:0031981 nuclear lumen
1.31 1.14e-08 GO:0043233 organelle lumen
1.30 2.98e-08 GO:0031974 membrane-enclosed lumen
1.31 4.07e-08 GO:0070013 intracellular organelle lumen
1.11 4.81e-07 GO:0005737 cytoplasm
1.35 1.99e-05 GO:0005654 nucleoplasm
1.03 2.05e-05 GO:0044464 cell part
1.03 2.16e-05 GO:0005623 cell
1.12 1.03e-04 GO:0044444 cytoplasmic part
1.13 1.22e-04 GO:0044446 intracellular organelle part
1.24 2.11e-04 GO:0005829 cytosol
1.13 2.28e-04 GO:0044422 organelle part
1.16 1.60e-03 GO:0032991 macromolecular complex
1.40 2.07e-03 GO:0044451 nucleoplasm part
1.46 3.54e-03 GO:0030529 ribonucleoprotein complex
1.43 7.51e-03 GO:0005694 chromosome
1.24 2.90e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 2.62e-06 GO:0003676 nucleic acid binding
1.45 3.52e-05 GO:0003723 RNA binding
1.05 1.29e-03 GO:0005488 binding
1.10 1.69e-03 GO:0005515 protein binding