Motif ID: MZF1.p2

Z-value: 1.832


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_63775901-0.204.5e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113574925 6.237 NM_001143945
GAS6
growth arrest-specific 6
chr19_-_36531958 6.020 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr9_+_108665168 4.488 NM_021224
ZNF462
zinc finger protein 462
chrX_+_154650590 3.820 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr1_+_199884152 3.696 NAV1
neuron navigator 1
chr1_+_199884072 3.540 NM_020443
NAV1
neuron navigator 1
chr8_+_22513043 3.470 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr11_+_129689536 3.420 FLJ34521
hypothetical protein LOC646383
chr20_-_47618059 3.411 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chrX_+_100361588 3.314 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr9_+_135880363 3.190 NCRNA00094
non-protein coding RNA 94
chr11_-_127897271 3.119 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chrX_+_73557809 3.083 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr6_-_42527760 2.815 NM_033502
TRERF1
transcriptional regulating factor 1
chr2_-_216944911 2.789 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr21_+_46226072 2.738 NM_001848
COL6A1
collagen, type VI, alpha 1
chr8_-_116750427 2.703 TRPS1
trichorhinophalangeal syndrome I
chr11_+_36354110 2.703 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr5_+_17270474 2.617 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr8_+_95722448 2.539 ESRP1
epithelial splicing regulatory protein 1
chr19_+_60487345 2.524 NM_032430
BRSK1
BR serine/threonine kinase 1
chr6_-_75972473 2.502 COL12A1
collagen, type XII, alpha 1
chr3_-_159306532 2.461 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr6_+_17501589 2.452 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr13_-_109236897 2.449 NM_003749
IRS2
insulin receptor substrate 2
chr20_-_61574259 2.443 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr3_-_121652183 2.408 NM_007085
FSTL1
follistatin-like 1
chr6_+_96570565 2.390 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr6_+_21774624 2.384 FLJ22536
hypothetical locus LOC401237
chr4_+_145786622 2.369 NM_022475
HHIP
hedgehog interacting protein
chr16_-_3225360 2.366 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr18_+_54682261 2.334 ZNF532
zinc finger protein 532
chr18_+_18003401 2.323 NM_005257
GATA6
GATA binding protein 6
chr19_-_52667056 2.318 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_+_52618815 2.289 NM_017410
HOXC13
homeobox C13
chr5_+_176493233 2.275 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr21_-_27261276 2.274 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_+_48610796 2.266 NM_001198595
NM_006873
STON1

stonin 1

chr5_+_176493488 2.241 NSD1
nuclear receptor binding SET domain protein 1
chr11_-_64167361 2.236 NM_138734
NRXN2
neurexin 2
chr6_-_170441493 2.195 NM_005618
DLL1
delta-like 1 (Drosophila)
chr19_+_60487578 2.191 BRSK1
BR serine/threonine kinase 1
chr17_+_58058783 2.173 MRC2
mannose receptor, C type 2
chr17_-_24069299 2.171 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr3_+_23219707 2.158 NM_152653
UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr8_+_95722575 2.154 ESRP1
epithelial splicing regulatory protein 1
chr11_+_66499323 2.142 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr8_-_116750277 2.141 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr5_+_82803248 2.137 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr17_-_39265705 2.120 MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr2_-_144991556 2.082 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_70952572 2.077 LOC283392
hypothetical LOC283392
chr8_+_95722516 2.076 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr16_+_12902955 2.062 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr9_-_14304036 2.037 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr10_-_79067552 2.033 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr8_+_1909437 2.031 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr12_+_64504835 2.026 HMGA2
high mobility group AT-hook 2
chr4_-_7095566 2.012 NM_153376
CCDC96
coiled-coil domain containing 96
chr5_-_127901633 2.002 NM_001999
FBN2
fibrillin 2
chr6_-_72187168 1.982 C6orf155
chromosome 6 open reading frame 155
chr12_+_4253143 1.970 NM_001759
CCND2
cyclin D2
chr4_+_30330963 1.966 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr19_-_13478037 1.945 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr5_+_129268352 1.944 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr5_+_17270781 1.936 BASP1
brain abundant, membrane attached signal protein 1
chr1_-_103346639 1.910 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr12_+_63958689 1.899 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr12_+_63958949 1.893 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr22_-_28972683 1.882 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_165996031 1.868 LOC100132188
LP7097
chr11_+_124539814 1.866 PKNOX2
PBX/knotted 1 homeobox 2
chr4_-_158111995 1.835 NM_016205
PDGFC
platelet derived growth factor C
chr6_-_10520592 1.830 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_18255753 1.823 FLJ35934
FLJ35934
chr11_-_127897098 1.817 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr12_+_70952729 1.808 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr12_-_46438447 1.806 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr9_-_4290028 1.790 NM_001042413
GLIS3
GLIS family zinc finger 3
chr22_-_44751671 1.788 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr1_+_18830086 1.783 NM_001135254
NM_002584
NM_013945
PAX7


paired box 7


chr6_-_167195987 1.764 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr18_-_55515623 1.762 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr2_+_45022540 1.757 NM_005413
SIX3
SIX homeobox 3
chr15_-_81667169 1.747 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr8_-_11096257 1.747 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr16_-_63713382 1.744 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_56004366 1.739 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr1_+_158636987 1.736 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr6_-_10523424 1.733 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_194844299 1.729 KCNT2
potassium channel, subfamily T, member 2
chr11_-_76862197 1.716 NM_001128620
NM_002576
PAK1

p21 protein (Cdc42/Rac)-activated kinase 1

chr17_-_24068759 1.704 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr15_-_77170135 1.703 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr9_+_138341752 1.703 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr1_-_72520735 1.699 NM_173808
NEGR1
neuronal growth regulator 1
chr2_-_144994349 1.694 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr8_-_75396016 1.680 NM_020647
JPH1
junctophilin 1
chr18_-_27518392 1.637 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr1_-_103346482 1.611 COL11A1
collagen, type XI, alpha 1
chrX_-_62891712 1.602 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr5_-_64813459 1.594 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chrX_+_72699757 1.591 CHIC1
cysteine-rich hydrophobic domain 1
chr19_-_51168396 1.587 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr4_-_140696740 1.586 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr8_-_119703361 1.579 NM_001101676
NM_207506
SAMD12

sterile alpha motif domain containing 12

chr19_-_56178882 1.572 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr18_-_21186107 1.569 NM_015461
ZNF521
zinc finger protein 521
chrX_+_72699686 1.566 NM_001039840
CHIC1
cysteine-rich hydrophobic domain 1
chr2_+_48610567 1.566 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chrX_-_62891730 1.562 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr12_+_74071145 1.541 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr6_+_133604181 1.531 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr8_+_22078622 1.530 BMP1
bone morphogenetic protein 1
chr19_-_1966628 1.528 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr19_+_46416938 1.523 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr3_-_189354510 1.516 LOC339929
hypothetical LOC339929
chr6_-_167195647 1.516 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_+_8865547 1.515 NM_004822
NTN1
netrin 1
chr16_-_30929217 1.513 NM_052874
STX1B
syntaxin 1B
chr10_-_69505048 1.509 NM_015601
NM_022079
HERC4

hect domain and RLD 4

chr5_-_9599157 1.509 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr13_-_39075200 1.506 LHFP
lipoma HMGIC fusion partner
chr15_-_80125403 1.504 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr16_-_63713466 1.504 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_+_54352843 1.499 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_-_52666886 1.498 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr17_+_7252225 1.490 NM_020795
NLGN2
neuroligin 2
chr3_-_64648703 1.486 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr5_-_92942680 1.485 FLJ42709
hypothetical LOC441094
chr19_-_242335 1.484 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr11_+_35596310 1.474 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr22_-_26527469 1.472 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr12_+_52689062 1.468 NM_022658
HOXC8
homeobox C8
chr6_+_127481740 1.446 NM_032784
RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr18_+_53170718 1.439 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_-_219558517 1.433 NM_017521
FEV
FEV (ETS oncogene family)
chr11_-_6396864 1.431 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr4_-_174326880 1.426


chr1_+_216585298 1.424 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr8_-_9045548 1.419 NM_024607
PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr16_-_63713485 1.415 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_-_29708838 1.406 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_68275520 1.405 NM_001039656
NM_004923
MTL5

metallothionein-like 5, testis-specific (tesmin)

chr10_-_79067296 1.395 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_194844061 1.395 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr3_+_52419554 1.388 NM_016483
NM_173341
PHF7

PHD finger protein 7

chr19_-_50963942 1.380


chr2_-_225158272 1.380 CUL3
cullin 3
chr4_+_41057600 1.377


chr7_+_114349376 1.376 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chrX_+_12066505 1.367 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr6_+_116798791 1.366 NM_013352
DSE
dermatan sulfate epimerase
chr2_+_85834111 1.365 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr2_-_159021201 1.359 NM_001171637
NM_138803
CCDC148

coiled-coil domain containing 148

chr10_+_102881050 1.358 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr17_+_30594192 1.355 NM_144975
SLFN5
schlafen family member 5
chr15_+_90197884 1.351 NM_001145044
NM_013272
SLCO3A1

solute carrier organic anion transporter family, member 3A1

chr19_-_242168 1.341 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr1_+_89871281 1.340 LRRC8C
leucine rich repeat containing 8 family, member C
chrX_+_71047344 1.340 NM_001013627
NHSL2
NHS-like 2
chr5_-_171813960 1.339 SH3PXD2B
SH3 and PX domains 2B
chr1_-_222688623 1.332 NM_001115113
NM_025160
WDR26

WD repeat domain 26

chr9_+_129414287 1.331 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr8_+_37672427 1.326 NM_025069
ZNF703
zinc finger protein 703
chr19_+_46416975 1.318 AXL
AXL receptor tyrosine kinase
chr12_+_101875581 1.311 NM_004316
ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr2_+_69093641 1.308 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr2_-_144994038 1.308 ZEB2
zinc finger E-box binding homeobox 2
chr19_-_9908014 1.297 NM_058164
OLFM2
olfactomedin 2
chr17_+_58058479 1.296 NM_006039
MRC2
mannose receptor, C type 2
chr19_-_8581559 1.294 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr10_-_126839056 1.293 NM_001329
CTBP2
C-terminal binding protein 2
chr9_-_124030770 1.291 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr12_-_6354818 1.290 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr10_-_79067476 1.288 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_225158349 1.287 NM_003590
CUL3
cullin 3
chr19_+_54352809 1.286 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr15_-_80125514 1.284 MEX3B
mex-3 homolog B (C. elegans)
chr8_+_22078817 1.281 BMP1
bone morphogenetic protein 1
chr16_+_31390567 1.277 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr4_+_81406765 1.273 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr6_-_165995510 1.270 NM_001130690
NM_006661
PDE10A

phosphodiesterase 10A

chr3_+_156280338 1.269 NM_007287
MME
membrane metallo-endopeptidase
chr4_+_151218862 1.259 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr12_+_47495567 1.257 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_45090025 1.249 NM_016932
SIX2
SIX homeobox 2
chr4_-_11039600 1.249 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr16_+_54782751 1.247 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr5_-_141041982 1.247 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_155130146 1.240 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr11_+_5574440 1.239 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr1_-_1139358 1.236 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr4_-_46086528 1.235 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr5_+_176493752 1.230 NSD1
nuclear receptor binding SET domain protein 1
chr6_-_153494076 1.220 NM_012419
RGS17
regulator of G-protein signaling 17
chr5_-_176833197 1.218 DBN1
drebrin 1
chr6_+_127481496 1.211 RSPO3
R-spondin 3 homolog (Xenopus laevis)
chr19_+_43572679 1.205 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chrX_+_111212908 1.205 NM_001004308
ZCCHC16
zinc finger, CCHC domain containing 16

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.39 2.34e-23 GO:0007399 nervous system development
1.22 2.72e-21 GO:0032502 developmental process
1.23 8.61e-21 GO:0007275 multicellular organismal development
1.25 4.64e-20 GO:0048731 system development
1.12 1.24e-19 GO:0065007 biological regulation
1.13 2.50e-19 GO:0050794 regulation of cellular process
1.23 3.52e-19 GO:0048856 anatomical structure development
1.13 1.68e-18 GO:0050789 regulation of biological process
1.29 9.20e-18 GO:0030154 cell differentiation
1.34 1.10e-17 GO:0009653 anatomical structure morphogenesis
1.08 1.23e-17 GO:0009987 cellular process
1.27 9.27e-17 GO:0048869 cellular developmental process
1.42 1.76e-15 GO:0022008 neurogenesis
1.42 2.15e-14 GO:0048699 generation of neurons
1.23 5.29e-14 GO:0048522 positive regulation of cellular process
1.22 5.56e-14 GO:0048518 positive regulation of biological process
1.18 8.24e-14 GO:0031323 regulation of cellular metabolic process
1.23 4.72e-13 GO:0048519 negative regulation of biological process
1.23 7.34e-12 GO:0048523 negative regulation of cellular process
1.16 7.82e-12 GO:0019222 regulation of metabolic process
1.17 9.22e-12 GO:0080090 regulation of primary metabolic process
1.50 1.27e-11 GO:0000904 cell morphogenesis involved in differentiation
1.42 1.72e-11 GO:0030182 neuron differentiation
1.17 4.66e-11 GO:0060255 regulation of macromolecule metabolic process
1.48 2.14e-10 GO:0031175 neuron projection development
1.35 4.13e-10 GO:0048468 cell development
1.44 4.48e-10 GO:0048666 neuron development
1.37 4.64e-10 GO:0051128 regulation of cellular component organization
1.50 5.61e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
1.50 6.11e-10 GO:0048812 neuron projection morphogenesis
1.29 7.70e-10 GO:0009893 positive regulation of metabolic process
1.30 9.22e-10 GO:0031325 positive regulation of cellular metabolic process
1.15 1.02e-09 GO:0023052 signaling
1.33 1.28e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 4.52e-09 GO:0010604 positive regulation of macromolecule metabolic process
1.49 4.56e-09 GO:0007409 axonogenesis
1.40 5.64e-09 GO:0032989 cellular component morphogenesis
1.41 6.28e-09 GO:0000902 cell morphogenesis
1.38 6.38e-09 GO:0009790 embryo development
1.36 7.97e-09 GO:0010557 positive regulation of macromolecule biosynthetic process
1.34 1.44e-08 GO:0031328 positive regulation of cellular biosynthetic process
1.18 1.73e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.33 1.77e-08 GO:0009891 positive regulation of biosynthetic process
1.18 2.60e-08 GO:0009889 regulation of biosynthetic process
1.44 2.70e-08 GO:0048858 cell projection morphogenesis
1.23 3.42e-08 GO:0023051 regulation of signaling
1.18 4.31e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 4.36e-08 GO:0032990 cell part morphogenesis
1.50 5.19e-08 GO:0009792 embryo development ending in birth or egg hatching
1.50 6.14e-08 GO:0043009 chordate embryonic development
1.34 6.36e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.42 6.39e-08 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 6.72e-08 GO:0009887 organ morphogenesis
1.37 6.95e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.17 7.98e-08 GO:0031326 regulation of cellular biosynthetic process
1.36 8.58e-08 GO:0045595 regulation of cell differentiation
1.31 1.02e-07 GO:0050793 regulation of developmental process
1.38 1.14e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.52 1.16e-07 GO:0007411 axon guidance
1.34 1.24e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.34e-07 GO:0048513 organ development
1.18 1.46e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.56 1.50e-07 GO:0035295 tube development
1.18 1.78e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 1.79e-07 GO:0010628 positive regulation of gene expression
1.36 2.35e-07 GO:0051254 positive regulation of RNA metabolic process
1.31 2.52e-07 GO:0006351 transcription, DNA-dependent
1.36 7.51e-07 GO:0030030 cell projection organization
1.23 9.66e-07 GO:0009966 regulation of signal transduction
1.14 2.54e-06 GO:0007165 signal transduction
1.18 2.68e-06 GO:0051252 regulation of RNA metabolic process
1.16 3.03e-06 GO:0010468 regulation of gene expression
1.71 3.40e-06 GO:0045165 cell fate commitment
1.11 4.91e-06 GO:0043170 macromolecule metabolic process
1.40 5.09e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.14 5.25e-06 GO:0016043 cellular component organization
1.12 8.99e-06 GO:0051716 cellular response to stimulus
1.15 1.50e-05 GO:0071842 cellular component organization at cellular level
1.13 3.48e-05 GO:0071840 cellular component organization or biogenesis
1.44 3.70e-05 GO:0007389 pattern specification process
1.36 4.32e-05 GO:0007417 central nervous system development
1.11 4.34e-05 GO:0044260 cellular macromolecule metabolic process
1.17 4.72e-05 GO:0006355 regulation of transcription, DNA-dependent
1.42 6.23e-05 GO:0048598 embryonic morphogenesis
1.18 6.38e-05 GO:0048583 regulation of response to stimulus
1.25 7.75e-05 GO:0032774 RNA biosynthetic process
1.29 7.92e-05 GO:2000026 regulation of multicellular organismal development
1.14 1.26e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.21 1.37e-04 GO:0051239 regulation of multicellular organismal process
1.26 1.45e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.43 1.89e-04 GO:0060284 regulation of cell development
1.07 2.98e-04 GO:0008152 metabolic process
1.50 3.03e-04 GO:0051129 negative regulation of cellular component organization
1.25 3.23e-04 GO:0031324 negative regulation of cellular metabolic process
1.56 3.63e-04 GO:0035239 tube morphogenesis
1.08 3.93e-04 GO:0044238 primary metabolic process
1.25 4.41e-04 GO:0009888 tissue development
1.48 5.38e-04 GO:0003002 regionalization
1.29 5.64e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.23 6.31e-04 GO:0009892 negative regulation of metabolic process
1.43 7.34e-04 GO:0048729 tissue morphogenesis
1.45 9.73e-04 GO:0001568 blood vessel development
1.40 9.83e-04 GO:0051093 negative regulation of developmental process
1.13 1.02e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 1.04e-03 GO:0042221 response to chemical stimulus
1.29 1.06e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.45 1.16e-03 GO:0045596 negative regulation of cell differentiation
1.27 1.65e-03 GO:0009890 negative regulation of biosynthetic process
1.56 1.78e-03 GO:0009952 anterior/posterior pattern formation
1.41 1.83e-03 GO:0051130 positive regulation of cellular component organization
1.08 1.88e-03 GO:0044237 cellular metabolic process
1.23 1.96e-03 GO:0042127 regulation of cell proliferation
1.11 2.01e-03 GO:0006807 nitrogen compound metabolic process
1.27 2.27e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.42 2.35e-03 GO:0061061 muscle structure development
1.46 2.44e-03 GO:0048568 embryonic organ development
1.47 2.53e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.16 3.14e-03 GO:0010467 gene expression
1.77 3.54e-03 GO:0048706 embryonic skeletal system development
1.41 4.06e-03 GO:0001944 vasculature development
1.56 4.09e-03 GO:0060562 epithelial tube morphogenesis
1.38 4.15e-03 GO:0045597 positive regulation of cell differentiation
1.16 4.20e-03 GO:0016070 RNA metabolic process
1.28 4.72e-03 GO:0009725 response to hormone stimulus
1.32 4.77e-03 GO:0051094 positive regulation of developmental process
1.31 4.99e-03 GO:0072358 cardiovascular system development
1.31 4.99e-03 GO:0072359 circulatory system development
1.47 5.03e-03 GO:0001701 in utero embryonic development
1.19 5.74e-03 GO:0010033 response to organic substance
1.16 5.77e-03 GO:0009059 macromolecule biosynthetic process
1.29 5.89e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.45 6.30e-03 GO:0002009 morphogenesis of an epithelium
1.14 7.07e-03 GO:0065008 regulation of biological quality
1.10 7.53e-03 GO:0051179 localization
1.16 7.74e-03 GO:0034645 cellular macromolecule biosynthetic process
1.27 8.47e-03 GO:0010629 negative regulation of gene expression
1.11 8.58e-03 GO:0034641 cellular nitrogen compound metabolic process
1.47 8.91e-03 GO:0045664 regulation of neuron differentiation
1.69 8.96e-03 GO:0030326 embryonic limb morphogenesis
1.69 8.96e-03 GO:0035113 embryonic appendage morphogenesis
1.31 9.35e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.21 9.62e-03 GO:0007154 cell communication
1.34 9.83e-03 GO:0007264 small GTPase mediated signal transduction
1.37 9.84e-03 GO:0001501 skeletal system development
1.26 1.01e-02 GO:0009719 response to endogenous stimulus
1.30 1.06e-02 GO:0019226 transmission of nerve impulse
1.30 1.06e-02 GO:0035637 multicellular organismal signaling
1.42 1.17e-02 GO:0050767 regulation of neurogenesis
1.32 1.21e-02 GO:0032583 regulation of gene-specific transcription
1.35 1.22e-02 GO:0007420 brain development
1.33 1.57e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.54 1.58e-02 GO:0001655 urogenital system development
1.22 1.77e-02 GO:0008219 cell death
1.35 1.77e-02 GO:0071495 cellular response to endogenous stimulus
1.26 1.83e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 2.16e-02 GO:0016265 death
1.27 2.32e-02 GO:0051253 negative regulation of RNA metabolic process
1.61 2.37e-02 GO:0072001 renal system development
1.13 2.53e-02 GO:0090304 nucleic acid metabolic process
1.26 2.55e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.61 2.70e-02 GO:0001822 kidney development
1.38 2.73e-02 GO:0051960 regulation of nervous system development
1.08 2.90e-02 GO:0032501 multicellular organismal process
1.33 3.02e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.36 3.40e-02 GO:0032870 cellular response to hormone stimulus
1.90 3.86e-02 GO:0021510 spinal cord development
1.30 4.16e-02 GO:0007268 synaptic transmission
1.60 4.41e-02 GO:0035107 appendage morphogenesis
1.60 4.41e-02 GO:0035108 limb morphogenesis
1.44 4.61e-02 GO:0007517 muscle organ development
1.30 4.70e-02 GO:0040008 regulation of growth
1.36 5.00e-02 GO:0030029 actin filament-based process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 3.74e-10 GO:0044424 intracellular part
1.05 2.14e-09 GO:0005622 intracellular
1.07 2.61e-09 GO:0043226 organelle
1.07 3.50e-09 GO:0043229 intracellular organelle
1.07 1.53e-08 GO:0043227 membrane-bounded organelle
1.07 1.80e-08 GO:0043231 intracellular membrane-bounded organelle
1.10 4.05e-08 GO:0005634 nucleus
1.07 8.91e-08 GO:0005737 cytoplasm
1.33 1.81e-06 GO:0030054 cell junction
1.16 1.33e-05 GO:0005829 cytosol
1.16 2.05e-04 GO:0031981 nuclear lumen
1.65 4.90e-04 GO:0030055 cell-substrate junction
1.66 1.02e-03 GO:0005925 focal adhesion
1.54 1.08e-03 GO:0005912 adherens junction
1.64 1.44e-03 GO:0005924 cell-substrate adherens junction
1.17 2.09e-03 GO:0005654 nucleoplasm
1.32 2.61e-03 GO:0043005 neuron projection
1.13 2.76e-03 GO:0043233 organelle lumen
1.02 3.42e-03 GO:0005623 cell
1.02 3.95e-03 GO:0044464 cell part
1.40 4.54e-03 GO:0016323 basolateral plasma membrane
1.11 4.80e-03 GO:0043234 protein complex
1.07 5.02e-03 GO:0044444 cytoplasmic part
1.12 5.53e-03 GO:0070013 intracellular organelle lumen
1.29 1.20e-02 GO:0045202 synapse
1.12 1.30e-02 GO:0031974 membrane-enclosed lumen
1.12 2.14e-02 GO:0044428 nuclear part
1.44 2.16e-02 GO:0070161 anchoring junction
1.19 4.74e-02 GO:0031982 vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.34e-22 GO:0005515 protein binding
1.52 2.63e-19 GO:0043565 sequence-specific DNA binding
1.37 4.25e-14 GO:0001071 nucleic acid binding transcription factor activity
1.37 4.25e-14 GO:0003700 sequence-specific DNA binding transcription factor activity
1.06 6.99e-13 GO:0005488 binding
1.34 4.79e-12 GO:0030528 transcription regulator activity
1.60 1.55e-06 GO:0010843 promoter binding
1.58 2.81e-06 GO:0000975 regulatory region DNA binding
1.58 2.81e-06 GO:0001067 regulatory region nucleic acid binding
1.58 2.81e-06 GO:0044212 transcription regulatory region DNA binding
1.37 2.91e-05 GO:0019904 protein domain specific binding
1.44 4.66e-05 GO:0008134 transcription factor binding
2.08 4.43e-04 GO:0019888 protein phosphatase regulator activity
1.95 1.43e-03 GO:0019208 phosphatase regulator activity
1.28 2.39e-03 GO:0008092 cytoskeletal protein binding
1.34 7.39e-03 GO:0003779 actin binding
1.45 8.68e-03 GO:0043566 structure-specific DNA binding
1.29 1.39e-02 GO:0015267 channel activity
1.33 1.62e-02 GO:0016563 transcription activator activity
1.29 1.67e-02 GO:0022803 passive transmembrane transporter activity
2.15 3.50e-02 GO:0019212 phosphatase inhibitor activity
1.18 3.58e-02 GO:0030234 enzyme regulator activity
1.11 3.65e-02 GO:0003677 DNA binding