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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 1.233

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_57492236	3.069	NM_144684	ZNF480	zinc finger protein 480
chr4_-_25473528	1.777	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_+_42128521	1.452	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr13_+_19430906	1.429	NM_001190965	ZMYM2	zinc finger, MYM-type 2
chr21_+_16024241	1.345	NM_013396	USP25	ubiquitin specific peptidase 25
chr7_-_81910956	1.327	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_-_81910740	1.322		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_15875932	1.291	NM_015199	ANKRD28	ankyrin repeat domain 28
chr6_-_74420330	1.253		SLC17A5	solute carrier family 17 (anion/sugar transporter), member 5
chr12_+_129388543	1.246		PIWIL1	piwi-like 1 (Drosophila)
chr8_+_72918889	1.224
chr3_+_171558143	1.162	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr5_-_81082699	1.108	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr13_+_19430881	1.091		ZMYM2	zinc finger, MYM-type 2
chr13_+_19430788	1.085	NM_003453 NM_197968 NM_001190964	ZMYM2	zinc finger, MYM-type 2
chr8_+_72918772	1.043		LOC100132891	hypothetical LOC100132891
chr7_-_107883929	1.025	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr7_+_64975596	1.012	NM_173517	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr10_+_11099860	0.993	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr9_-_85622366	0.981	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr5_+_89806436	0.979	NM_006467	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr7_+_128257698	0.979	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr22_+_18081968	0.961	NM_002688	SEPT5	septin 5
chr1_+_234372454	0.955	NM_003272	GPR137B	G protein-coupled receptor 137B
chr10_-_74925753	0.947	NM_001142353 NM_001142354 NM_021132	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr22_+_38183262	0.938	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr6_+_135544170	0.932		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr5_-_114660139	0.930	NM_001040440	CCDC112	coiled-coil domain containing 112
chr1_+_35507145	0.928	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr1_-_32574185	0.919	NM_023009	MARCKSL1	MARCKS-like 1
chr10_+_11100075	0.917		CELF2	CUGBP, Elav-like family member 2
chr12_-_95317928	0.903		CDK17	cyclin-dependent kinase 17
chr5_-_137116746	0.897		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr21_-_39642808	0.895		HMGN1	high-mobility group nucleosome binding domain 1
chr16_-_19803606	0.882	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr6_-_85530617	0.880	NM_001080508	TBX18	T-box 18
chr3_+_171558188	0.870		SKIL	SKI-like oncogene
chr3_+_171558215	0.861		SKIL	SKI-like oncogene
chr2_-_210744158	0.858	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr18_+_12937972	0.856	NM_001013437 NM_031216	SEH1L	SEH1-like (S. cerevisiae)
chr6_+_133604181	0.855	NM_004100 NM_172103 NM_172105	EYA4	eyes absent homolog 4 (Drosophila)
chr10_+_93160066	0.853	NM_173497 NM_182765	HECTD2	HECT domain containing 2
chr10_-_74925653	0.850		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr1_+_224317044	0.821		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr3_-_184180985	0.804	NM_020640	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr1_+_78126787	0.802	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr2_+_191222077	0.801	NM_005966	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)
chr10_-_74925724	0.800		PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme
chr17_-_44010543	0.787	NM_024015	HOXB4	homeobox B4
chr6_+_18263514	0.779	NM_153042	KDM1B	lysine (K)-specific demethylase 1B
chr10_-_33286792	0.776	NM_133376	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr21_+_16024157	0.775		USP25	ubiquitin specific peptidase 25
chr19_-_54314090	0.773	NM_018111	C19orf73	chromosome 19 open reading frame 73
chr6_+_111911226	0.772		LOC643749	hypothetical LOC643749
chr1_+_65763978	0.769		LEPR	leptin receptor
chr17_+_63252668	0.766		BPTF	bromodomain PHD finger transcription factor
chr3_-_172660545	0.761	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr1_+_65763945	0.752	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr1_+_177261627	0.751		FAM20B	family with sequence similarity 20, member B
chr2_-_144991386	0.750		ZEB2	zinc finger E-box binding homeobox 2
chr6_+_135544138	0.744	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr5_-_88215034	0.738	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr10_+_89613399	0.729		PTEN	phosphatase and tensin homolog
chr11_+_46359878	0.721	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr17_+_63252704	0.720		BPTF	bromodomain PHD finger transcription factor
chr5_+_176493233	0.718	NM_022455	NSD1	nuclear receptor binding SET domain protein 1
chr9_-_15500209	0.708	NM_021144	PSIP1	PC4 and SFRS1 interacting protein 1
chr9_-_100510657	0.706	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr7_-_140270749	0.701	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr10_+_94598204	0.700	NM_019053	EXOC6	exocyst complex component 6
chr12_+_19484044	0.699		AEBP2	AE binding protein 2
chr1_+_39229474	0.698	NM_001136275 NM_024595	AKIRIN1	akirin 1
chr5_+_176493488	0.697		NSD1	nuclear receptor binding SET domain protein 1
chr7_-_27206249	0.694	NM_000522	HOXA13	homeobox A13
chr6_+_133604203	0.692		EYA4	eyes absent homolog 4 (Drosophila)
chr2_+_181553333	0.685	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr3_-_88190737	0.682	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr5_+_76542461	0.679	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_-_174537021	0.678	NM_001017371	SP3	Sp3 transcription factor
chr13_+_77170470	0.676	NM_001040153	SLAIN1	SLAIN motif family, member 1
chr12_-_122415327	0.676		SBNO1	strawberry notch homolog 1 (Drosophila)
chr10_+_49184658	0.662		MAPK8	mitogen-activated protein kinase 8
chrX_-_153952447	0.660	NM_001018024 NM_001018025	MTCP1NB MTCP1	mature T-cell proliferation 1 neighbor mature T-cell proliferation 1
chr17_+_63252087	0.655	NM_004459 NM_182641	BPTF	bromodomain PHD finger transcription factor
chr9_+_130491668	0.654		SET	SET nuclear oncogene
chr8_+_57286875	0.652		CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7
chr5_-_81082614	0.648		SSBP2	single-stranded DNA binding protein 2
chr2_+_56264627	0.645	NM_001080433	CCDC85A	coiled-coil domain containing 85A
chr16_+_65620536	0.640	NM_001755 NM_022845	CBFB	core-binding factor, beta subunit
chr22_+_42751487	0.640	NM_013327	PARVB	parvin, beta
chr2_+_198377561	0.639	NM_006226	PLCL1	phospholipase C-like 1
chr19_+_60487578	0.636		BRSK1	BR serine/threonine kinase 1
chr6_+_143423723	0.635		AIG1	androgen-induced 1
chr21_-_39642935	0.634		HMGN1	high-mobility group nucleosome binding domain 1
chr6_-_46566969	0.632		RCAN2	regulator of calcineurin 2
chr5_+_86599800	0.627		RASA1	RAS p21 protein activator (GTPase activating protein) 1
chr21_+_46473494	0.627		MCM3AP-AS1	MCM3AP antisense RNA 1 (non-protein coding)
chr8_+_16929116	0.623	NM_181723	EFHA2	EF-hand domain family, member A2
chr2_-_219141199	0.620	NM_020935	USP37	ubiquitin specific peptidase 37
chr20_-_30636535	0.614		LOC284804	hypothetical protein LOC284804
chr12_+_102982365	0.612	NM_013320	HCFC2	host cell factor C2
chr10_+_89613071	0.610	NM_000314	PTEN	phosphatase and tensin homolog
chr16_+_51722285	0.607		CHD9	chromodomain helicase DNA binding protein 9
chr12_+_19484387	0.604		AEBP2	AE binding protein 2
chr6_+_76368337	0.604	NM_001100409 NM_015571	SENP6	SUMO1/sentrin specific peptidase 6
chr3_+_20056857	0.603		KAT2B	K(lysine) acetyltransferase 2B
chr7_+_119700924	0.602	NM_012281	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2
chr8_+_17058377	0.600		ZDHHC2	zinc finger, DHHC-type containing 2
chr8_-_74821610	0.597		STAU2 LOC729696	staufen, RNA binding protein, homolog 2 (Drosophila) hypothetical protein LOC729696
chr11_+_107304344	0.597	NM_017516	RAB39	RAB39, member RAS oncogene family
chr18_-_802268	0.595	NM_005433	YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr14_-_52327895	0.591		GNPNAT1	glucosamine-phosphate N-acetyltransferase 1
chrX_-_16798383	0.588	NM_002893	RBBP7	retinoblastoma binding protein 7
chr9_+_130491291	0.584	NM_003011	SET	SET nuclear oncogene
chr6_+_84799969	0.582	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2
chr8_+_26204997	0.581		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr10_+_93160033	0.580
chr10_-_43082372	0.579	NM_145313	RASGEF1A	RasGEF domain family, member 1A
chr21_-_39642712	0.578		HMGN1	high-mobility group nucleosome binding domain 1
chr1_-_93199586	0.577	NM_001006605	FAM69A	family with sequence similarity 69, member A
chrX_-_16798363	0.573		RBBP7	retinoblastoma binding protein 7
chr12_+_75682016	0.572		ZDHHC17	zinc finger, DHHC-type containing 17
chr14_-_22840249	0.571
chr8_-_74821636	0.571	NM_001164380 NM_001164381 NM_001164382 NM_001164383 NM_001164385 NM_014393	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)
chr15_+_73922838	0.570		UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chr5_-_40834232	0.569		PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit
chr3_-_38666122	0.568	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr12_+_129388385	0.566	NM_001190971 NM_004764	PIWIL1	piwi-like 1 (Drosophila)
chr6_-_153494076	0.565	NM_012419	RGS17	regulator of G-protein signaling 17
chr7_+_106472243	0.565	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_35507197	0.564		ZMYM4	zinc finger, MYM-type 4
chr3_-_25680723	0.563	NM_001068	TOP2B	topoisomerase (DNA) II beta 180kDa
chr1_-_115433570	0.561	NM_005725	TSPAN2	tetraspanin 2
chr9_+_130491370	0.560		SET	SET nuclear oncogene
chr5_-_137396677	0.558	NM_001101800 NM_001101801 NM_016603	FAM13B	family with sequence similarity 13, member B
chr7_+_35807352	0.552		SEPT7	septin 7
chr15_+_73923047	0.551		UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chrX_-_16798096	0.550		RBBP7	retinoblastoma binding protein 7
chrX_-_135161185	0.550	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr10_-_64248932	0.550	NM_001136178	EGR2	early growth response 2
chr6_+_19945578	0.547	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr9_-_15500899	0.546	NM_001128217 NM_033222	PSIP1	PC4 and SFRS1 interacting protein 1
chr1_-_166171838	0.545	NM_015415	BRP44	brain protein 44
chr7_+_35807139	0.545	NM_001011553 NM_001788	SEPT7	septin 7
chr17_-_60345364	0.543	NM_199340	LRRC37A3	leucine rich repeat containing 37, member A3
chr11_+_32870935	0.540	NM_001076786	QSER1	glutamine and serine rich 1
chr5_-_167938875	0.539		PANK3	pantothenate kinase 3
chr6_-_79844618	0.539		PHIP	pleckstrin homology domain interacting protein
chr12_+_75682146	0.539		ZDHHC17	zinc finger, DHHC-type containing 17
chr7_+_64136078	0.537		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_+_210525885	0.536		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr14_-_101623139	0.536	NM_005348	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr12_+_50271283	0.535	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr3_+_23822481	0.533		UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr7_-_120823556	0.532		FAM3C	family with sequence similarity 3, member C
chr12_+_49444509	0.531		ATF1	activating transcription factor 1
chr18_+_12938010	0.529		SEH1L	SEH1-like (S. cerevisiae)
chr2_-_225615556	0.523	NM_014689	DOCK10	dedicator of cytokinesis 10
chr6_+_76367944	0.522		SENP6	SUMO1/sentrin specific peptidase 6
chr12_-_99060590	0.520		UHRF1BP1L	UHRF1 binding protein 1-like
chr7_+_64975778	0.518		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr14_-_101623097	0.518		HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_-_181871473	0.517		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr13_+_24844084	0.516	NM_016529	ATP8A2	ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr8_+_172199	0.514	NM_173539 NM_001042415 NM_001042416	ZNF596	zinc finger protein 596
chr4_-_71924052	0.513	NM_001098477	GRSF1	G-rich RNA sequence binding factor 1
chr2_+_102602579	0.512	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr1_-_224441024	0.511	NM_022735	ACBD3	acyl-CoA binding domain containing 3
chr1_-_58784967	0.510	NM_145243	OMA1	OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr2_+_207016525	0.510	NM_003812	ADAM23	ADAM metallopeptidase domain 23
chr15_+_73922676	0.510	NM_173469	UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chr7_+_102502852	0.508		ARMC10	armadillo repeat containing 10
chr1_+_67168470	0.506	NM_001077701 NM_001077704	MIER1	mesoderm induction early response 1 homolog (Xenopus laevis)
chr9_-_126945536	0.506	NM_001144877 NM_173690	SCAI	suppressor of cancer cell invasion
chr12_+_69046241	0.505	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr13_-_40533072	0.504		ELF1	E74-like factor 1 (ets domain transcription factor)
chr6_+_76368462	0.504		SENP6	SUMO1/sentrin specific peptidase 6
chr2_+_181553613	0.503		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr5_-_114659863	0.503	NM_152549	CCDC112	coiled-coil domain containing 112
chr4_+_108965167	0.502	NM_001136258	SGMS2	sphingomyelin synthase 2
chr1_-_182273114	0.501		GLT25D2	glycosyltransferase 25 domain containing 2
chr4_+_154606900	0.501	NM_001131007 NM_015196	KIAA0922	KIAA0922
chr6_-_79844606	0.498		PHIP	pleckstrin homology domain interacting protein
chr12_-_116983276	0.497	NM_018639	WSB2	WD repeat and SOCS box containing 2
chr14_-_57688560	0.492	NM_001001872	C14orf37	chromosome 14 open reading frame 37
chr7_-_120823591	0.491	NM_001040020 NM_014888	FAM3C	family with sequence similarity 3, member C
chr12_-_99060771	0.490	NM_001006947 NM_015054	UHRF1BP1L	UHRF1 binding protein 1-like
chrX_-_19918958	0.490		LOC729609	hypothetical LOC729609
chr2_+_135392857	0.489	NM_001241 NM_058241	CCNT2	cyclin T2
chr1_-_181871416	0.487		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr9_-_134220179	0.486	NM_015046	SETX	senataxin
chr1_-_181871462	0.485		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr10_+_89613347	0.484		PTEN	phosphatase and tensin homolog
chrX_+_9392980	0.483	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr12_+_75681973	0.481	NM_015336	ZDHHC17	zinc finger, DHHC-type containing 17
chr10_+_64951114	0.479	NM_001001330	REEP3	receptor accessory protein 3
chr7_+_35807369	0.478		SEPT7	septin 7
chr1_-_224441023	0.477		ACBD3	acyl-CoA binding domain containing 3
chr10_+_94439658	0.476	NM_002729	HHEX	hematopoietically expressed homeobox
chr14_+_66777578	0.476	NM_022474	MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.22	1.07e-20	GO:0044237	cellular metabolic process
1.28	5.89e-20	GO:0044260	cellular macromolecule metabolic process
1.11	2.42e-17	GO:0009987	cellular process
1.23	2.98e-15	GO:0043170	macromolecule metabolic process
1.19	3.79e-15	GO:0044238	primary metabolic process
1.32	6.02e-14	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	4.07e-13	GO:0008152	metabolic process
1.16	5.08e-13	GO:0050794	regulation of cellular process
1.32	1.64e-12	GO:0044267	cellular protein metabolic process
1.27	1.96e-12	GO:0006807	nitrogen compound metabolic process
1.25	3.48e-12	GO:0031323	regulation of cellular metabolic process
1.38	3.63e-12	GO:0006464	protein modification process
1.27	4.00e-12	GO:0034641	cellular nitrogen compound metabolic process
1.15	8.34e-12	GO:0050789	regulation of biological process
1.14	1.22e-11	GO:0065007	biological regulation
1.26	3.45e-11	GO:0060255	regulation of macromolecule metabolic process
1.35	5.32e-11	GO:0043412	macromolecule modification
1.29	2.20e-10	GO:0010468	regulation of gene expression
1.22	2.39e-10	GO:0019222	regulation of metabolic process
1.24	4.97e-10	GO:0080090	regulation of primary metabolic process
1.84	2.84e-09	GO:0070647	protein modification by small protein conjugation or removal
1.28	5.23e-09	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.28	9.94e-09	GO:0010556	regulation of macromolecule biosynthetic process
1.88	2.15e-08	GO:0032446	protein modification by small protein conjugation
1.24	2.97e-08	GO:0019538	protein metabolic process
1.28	3.96e-08	GO:0051252	regulation of RNA metabolic process
1.25	7.63e-08	GO:0031326	regulation of cellular biosynthetic process
1.25	8.48e-08	GO:0009889	regulation of biosynthetic process
1.32	1.66e-07	GO:0016070	RNA metabolic process
1.28	1.78e-07	GO:0090304	nucleic acid metabolic process
1.24	5.90e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70	1.15e-06	GO:0016568	chromatin modification
1.83	1.48e-06	GO:0016567	protein ubiquitination
1.23	1.55e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.26	4.42e-06	GO:0006355	regulation of transcription, DNA-dependent
1.23	1.07e-05	GO:0071842	cellular component organization at cellular level
1.35	2.30e-05	GO:0044248	cellular catabolic process
1.52	3.33e-05	GO:0016071	mRNA metabolic process
1.42	5.91e-05	GO:0046907	intracellular transport
1.51	6.63e-05	GO:0044265	cellular macromolecule catabolic process
1.28	7.62e-05	GO:0006996	organelle organization
1.18	1.01e-04	GO:0016043	cellular component organization
1.20	1.20e-04	GO:0071841	cellular component organization or biogenesis at cellular level
2.17	1.67e-04	GO:0040029	regulation of gene expression, epigenetic
1.37	2.14e-04	GO:0022008	neurogenesis
1.31	2.44e-04	GO:0051641	cellular localization
1.43	4.10e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.17	4.35e-04	GO:0071840	cellular component organization or biogenesis
1.51	4.96e-04	GO:0006325	chromatin organization
1.28	5.28e-04	GO:0007399	nervous system development
1.61	6.12e-04	GO:0019941	modification-dependent protein catabolic process
2.30	6.17e-04	GO:0000209	protein polyubiquitination
1.60	6.87e-04	GO:0051603	proteolysis involved in cellular protein catabolic process
1.81	7.55e-04	GO:0016569	covalent chromatin modification
1.61	7.87e-04	GO:0006511	ubiquitin-dependent protein catabolic process
1.92	7.99e-04	GO:0006184	GTP catabolic process
1.60	8.84e-04	GO:0043632	modification-dependent macromolecule catabolic process
1.59	9.85e-04	GO:0009259	ribonucleotide metabolic process
1.58	1.04e-03	GO:0044257	cellular protein catabolic process
1.45	1.23e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.36	1.48e-03	GO:0048699	generation of neurons
1.64	1.56e-03	GO:0010608	posttranscriptional regulation of gene expression
1.55	1.83e-03	GO:0030163	protein catabolic process
1.79	1.98e-03	GO:0016570	histone modification
1.85	1.98e-03	GO:0046039	GTP metabolic process
1.46	2.03e-03	GO:0006753	nucleoside phosphate metabolic process
1.46	2.03e-03	GO:0009117	nucleotide metabolic process
1.50	2.17e-03	GO:0072521	purine-containing compound metabolic process
1.41	2.56e-03	GO:0009057	macromolecule catabolic process
1.52	2.66e-03	GO:0006163	purine nucleotide metabolic process
1.30	3.26e-03	GO:0051649	establishment of localization in cell
1.32	3.63e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.57	3.73e-03	GO:0009150	purine ribonucleotide metabolic process
1.31	5.78e-03	GO:0032268	regulation of cellular protein metabolic process
1.18	6.87e-03	GO:0009058	biosynthetic process
1.39	7.57e-03	GO:0051276	chromosome organization
1.19	7.67e-03	GO:0048522	positive regulation of cellular process
1.19	8.58e-03	GO:0044249	cellular biosynthetic process
1.20	9.31e-03	GO:0048523	negative regulation of cellular process
1.19	9.59e-03	GO:0048519	negative regulation of biological process
1.62	9.71e-03	GO:0072523	purine-containing compound catabolic process
1.56	9.86e-03	GO:0009141	nucleoside triphosphate metabolic process
1.56	1.07e-02	GO:0009144	purine nucleoside triphosphate metabolic process
1.49	1.13e-02	GO:0006397	mRNA processing
1.32	1.14e-02	GO:0006351	transcription, DNA-dependent
1.15	1.20e-02	GO:0051179	localization
1.56	1.22e-02	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.62	1.25e-02	GO:0006195	purine nucleotide catabolic process
1.56	1.44e-02	GO:0009199	ribonucleoside triphosphate metabolic process
1.21	1.79e-02	GO:0010467	gene expression
2.83	1.82e-02	GO:0070936	protein K48-linked ubiquitination
1.59	1.89e-02	GO:0009166	nucleotide catabolic process
1.22	1.89e-02	GO:0023051	regulation of signaling
1.50	1.90e-02	GO:0018193	peptidyl-amino acid modification
1.73	2.30e-02	GO:0006417	regulation of translation
1.63	2.34e-02	GO:0009261	ribonucleotide catabolic process
1.27	2.63e-02	GO:0010604	positive regulation of macromolecule metabolic process
1.28	2.69e-02	GO:0007049	cell cycle
1.63	3.01e-02	GO:0009203	ribonucleoside triphosphate catabolic process
1.63	3.01e-02	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.62	3.20e-02	GO:0009143	nucleoside triphosphate catabolic process
1.62	3.20e-02	GO:0009154	purine ribonucleotide catabolic process
2.08	3.25e-02	GO:0031123	RNA 3'-end processing
1.62	3.63e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.23	3.79e-02	GO:0009056	catabolic process
2.17	3.90e-02	GO:0031124	mRNA 3'-end processing
1.82	3.98e-02	GO:0006403	RNA localization
1.27	4.84e-02	GO:0051246	regulation of protein metabolic process
1.40	4.84e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.28	4.90e-02	GO:0006793	phosphorus metabolic process
1.28	4.90e-02	GO:0006796	phosphate metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.57e-47	GO:0044424	intracellular part
1.16	2.20e-47	GO:0005622	intracellular
1.18	1.20e-34	GO:0043226	organelle
1.18	1.69e-34	GO:0043229	intracellular organelle
1.28	2.32e-31	GO:0005634	nucleus
1.19	2.36e-31	GO:0043227	membrane-bounded organelle
1.19	3.92e-31	GO:0043231	intracellular membrane-bounded organelle
1.16	3.44e-21	GO:0005737	cytoplasm
1.34	6.27e-13	GO:0044428	nuclear part
1.36	5.90e-12	GO:0031981	nuclear lumen
1.05	6.12e-11	GO:0044464	cell part
1.05	6.64e-11	GO:0005623	cell
1.32	7.90e-11	GO:0005829	cytosol
1.41	1.17e-10	GO:0005654	nucleoplasm
1.15	1.48e-09	GO:0044444	cytoplasmic part
1.24	6.14e-09	GO:0043234	protein complex
1.21	6.58e-09	GO:0032991	macromolecular complex
1.15	1.26e-08	GO:0044446	intracellular organelle part
1.15	4.24e-08	GO:0044422	organelle part
1.26	6.80e-08	GO:0070013	intracellular organelle lumen
1.25	1.97e-07	GO:0031974	membrane-enclosed lumen
1.25	3.65e-07	GO:0043233	organelle lumen
2.20	4.14e-05	GO:0016585	chromatin remodeling complex
3.67	3.01e-04	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.72	1.56e-03	GO:0031252	cell leading edge
1.35	1.67e-03	GO:0044451	nucleoplasm part
1.16	2.69e-03	GO:0043228	non-membrane-bounded organelle
1.16	2.69e-03	GO:0043232	intracellular non-membrane-bounded organelle
2.32	4.14e-03	GO:0035770	RNA granule
1.45	1.67e-02	GO:0048471	perinuclear region of cytoplasm
1.30	4.08e-02	GO:0015630	microtubule cytoskeleton
1.57	4.65e-02	GO:0030425	dendrite

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	3.51e-27	GO:0005515	protein binding
1.11	2.00e-21	GO:0005488	binding
1.23	4.02e-10	GO:0003676	nucleic acid binding
1.29	5.32e-10	GO:0000166	nucleotide binding
1.23	3.38e-06	GO:0003677	DNA binding
1.40	1.04e-05	GO:0003723	RNA binding
1.24	1.43e-05	GO:0008270	zinc ion binding
1.67	1.72e-05	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.75	3.34e-05	GO:0019787	small conjugating protein ligase activity
1.70	3.42e-05	GO:0016881	acid-amino acid ligase activity
2.73	1.10e-04	GO:0046332	SMAD binding
1.24	1.19e-04	GO:0032553	ribonucleotide binding
1.24	1.19e-04	GO:0032555	purine ribonucleotide binding
1.15	1.29e-04	GO:0046872	metal ion binding
1.23	1.32e-04	GO:0017076	purine nucleotide binding
1.15	1.70e-04	GO:0043167	ion binding
1.15	2.14e-04	GO:0043169	cation binding
1.23	2.39e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.20	2.83e-04	GO:0046914	transition metal ion binding
1.65	2.00e-03	GO:0004842	ubiquitin-protein ligase activity
1.28	5.09e-03	GO:0030528	transcription regulator activity
1.67	6.93e-03	GO:0003682	chromatin binding
1.32	1.15e-02	GO:0019899	enzyme binding
1.21	1.37e-02	GO:0030554	adenyl nucleotide binding
1.21	1.43e-02	GO:0032559	adenyl ribonucleotide binding
1.40	1.65e-02	GO:0016874	ligase activity
1.43	2.73e-02	GO:0003712	transcription cofactor activity
1.43	3.11e-02	GO:0000988	protein binding transcription factor activity
1.43	3.11e-02	GO:0000989	transcription factor binding transcription factor activity
3.87	3.47e-02	GO:0070411	I-SMAD binding
1.20	4.25e-02	GO:0005524	ATP binding
1.10	4.27e-02	GO:0003824	catalytic activity
1.57	4.51e-02	GO:0003924	GTPase activity