Motif ID: CUX2.p2

Z-value: 0.418


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CUX2chr12_+_1099562100.116.9e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_196874759 0.392 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr13_-_45654292 0.358 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_45654296 0.358 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_132196533 0.343 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr7_-_92615593 0.322 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr2_-_88946767 0.319


chr1_+_246150942 0.264 NM_001005522
OR2T8
olfactory receptor, family 2, subfamily T, member 8
chr11_+_22646229 0.237 NM_177553
GAS2
growth arrest-specific 2
chr11_-_74478405 0.229 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr13_-_45654327 0.227 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_196874839 0.224 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_23476497 0.217 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr11_+_59038961 0.187 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chr3_+_153499883 0.186 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr3_+_35696119 0.178 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr8_-_108579270 0.159 NM_001146
ANGPT1
angiopoietin 1
chr7_-_100077072 0.146 NM_003227
TFR2
transferrin receptor 2
chr1_+_196874867 0.142 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_169634330 0.135 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_27815475 0.134 NM_001146221
LOC100287284
MANSC domain-containing protein ENSP00000370673
chr12_-_7709734 0.133 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr5_-_160044844 0.127 ATP10B
ATPase, class V, type 10B
chr9_-_5294579 0.125 NM_005059
NM_134441
RLN2

relaxin 2

chr10_+_68355797 0.120 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr8_+_77756077 0.114 ZFHX4
zinc finger homeobox 4
chr12_-_52939584 0.107 NM_001127322
CBX5
chromobox homolog 5
chrX_+_123307812 0.106 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr12_-_52939636 0.101 NM_001127321
CBX5
chromobox homolog 5
chr13_-_35327798 0.092 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr1_+_160002746 0.092 ATF6
activating transcription factor 6
chr6_-_161614962 0.091 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_-_154719560 0.088 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr17_-_30545489 0.088 NM_152462
AMAC1
acyl-malonyl condensing enzyme 1
chr11_-_58368555 0.087 NM_145016
GLYATL2
glycine-N-acyltransferase-like 2
chr17_-_44043278 0.086 HOXB7
homeobox B7
chr12_-_53661888 0.086 NM_001098815
KIAA0748
KIAA0748
chr17_-_44043361 0.084 NM_004502
HOXB7
homeobox B7
chr1_+_160002733 0.083 ATF6
activating transcription factor 6
chr14_+_87560646 0.083 LOC283587
hypothetical protein LOC283587
chr12_+_109956210 0.082 NM_015267
CUX2
cut-like homeobox 2
chr3_-_15773061 0.079 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr8_+_18293034 0.079 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr14_-_20098929 0.077 NM_001001673
NM_001110356
NM_001110357
NM_001110358
NM_001110359
NM_001110360
NM_001110361
RNASE9






ribonuclease, RNase A family, 9 (non-active)






chr1_-_51660328 0.074 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr6_-_68655708 0.074


chr8_+_77756061 0.073 NM_024721
ZFHX4
zinc finger homeobox 4
chr16_+_11966464 0.071 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr14_+_28311740 0.070 C14orf23
chromosome 14 open reading frame 23
chr8_-_86477585 0.069 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr13_-_83354425 0.067 SLITRK1
SLIT and NTRK-like family, member 1
chr5_+_40877053 0.067 NM_032587
CARD6
caspase recruitment domain family, member 6
chr17_-_44042924 0.066 HOXB7
homeobox B7
chr1_+_160002693 0.066 NM_007348
ATF6
activating transcription factor 6
chr1_+_357502 0.065 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr10_-_69125932 0.065 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr8_-_82557956 0.063 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr1_+_103961476 0.063 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr11_+_5732498 0.061 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chr1_-_611896 0.060 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr7_+_99263571 0.059 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr7_-_36730525 0.058 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr12_+_40117751 0.057 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr7_-_112515035 0.056 GPR85
G protein-coupled receptor 85
chr6_-_10939095 0.053 NM_005906
MAK
male germ cell-associated kinase
chr7_-_91632525 0.052 NM_001161528
LOC401387
leucine-rich repeat and death domain-containing protein
chr20_+_31219543 0.049 NM_080574
C20orf70
chromosome 20 open reading frame 70
chr3_+_63403792 0.048 NM_144642
SYNPR
synaptoporin
chr19_-_53935648 0.047 NM_017805
RASIP1
Ras interacting protein 1
chr7_-_112515068 0.047 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr4_-_70861301 0.046 NM_001891
CSN2
casein beta
chr11_+_61794205 0.045 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr10_+_92621221 0.045 RPP30
ribonuclease P/MRP 30kDa subunit
chr4_-_72868598 0.044 NM_000583
GC
group-specific component (vitamin D binding protein)
chr16_+_29971955 0.044 ALDOA
aldolase A, fructose-bisphosphate
chr5_+_57823017 0.044 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr10_-_42183441 0.044 LOC283027
hypothetical protein LOC283027
chr1_+_185064654 0.043 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrX_+_134482212 0.043 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr10_+_90474280 0.042 NM_001080518
LIPK
lipase, family member K
chr2_-_162717159 0.042 NM_002054
GCG
glucagon
chr3_-_15814678 0.040 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr12_+_21570457 0.040 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr12_-_116890410 0.040 NM_173598
KSR2
kinase suppressor of ras 2
chr3_+_44667504 0.038 ZNF35
zinc finger protein 35
chrX_-_135166306 0.038 NM_001173516
MAP7D3
MAP7 domain containing 3
chr3_+_85858321 0.037 NM_153184
CADM2
cell adhesion molecule 2
chr13_+_51933228 0.036 CKAP2
cytoskeleton associated protein 2
chr3_+_135996734 0.036 NM_004441
EPHB1
EPH receptor B1
chr13_-_83354474 0.035 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr6_+_32817140 0.035 NM_020056
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr6_+_159229606 0.034 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chrX_-_63532057 0.034 NM_017677
MTMR8
myotubularin related protein 8
chr4_-_77176163 0.034 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr11_-_5766621 0.033 NM_001001913
OR52N1
olfactory receptor, family 52, subfamily N, member 1
chr4_+_77214886 0.032 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr6_-_26216299 0.032 NM_005323
HIST1H1T
histone cluster 1, H1t
chr17_+_36599664 0.032 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr12_-_11230809 0.031 NM_181429
TAS2R42
taste receptor, type 2, member 42
chr11_-_34489693 0.030 NM_198381
ELF5
E74-like factor 5 (ets domain transcription factor)
chr17_+_53670785 0.030 NM_001160102
NM_006151
LPO

lactoperoxidase

chrX_-_11194015 0.029 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr22_-_38619739 0.028 NM_152512
ENTHD1
ENTH domain containing 1
chr5_+_140227951 0.028 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr8_+_11225904 0.027 NM_054028
AMAC1L2
acyl-malonyl condensing enzyme 1-like 2
chr17_-_77469316 0.027 SIRT7
sirtuin 7
chr15_+_56511466 0.027 NM_000236
LIPC
lipase, hepatic
chr18_+_59767567 0.026 NM_001123366
HMSD
histocompatibility (minor) serpin domain containing
chr12_-_10870134 0.026 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr10_-_69095362 0.026 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr4_+_71330797 0.026 NM_001145006
MUC7
mucin 7, secreted
chr16_+_65938753 0.025 NM_001161575
LRRC36
leucine rich repeat containing 36
chr11_+_55899675 0.025 NM_001005204
NM_001013356
OR8U1
OR8U8
olfactory receptor, family 8, subfamily U, member 1
olfactory receptor, family 8, subfamily U, member 8
chr4_-_47160476 0.025 COMMD8
COMM domain containing 8
chrX_-_118610880 0.024 NM_001173488
NKRF
NFKB repressing factor
chr4_-_68766392 0.024 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr9_-_114814286 0.023 NM_001101338
ZNF883
zinc finger protein 883
chr8_+_17874128 0.023 PCM1
pericentriolar material 1
chr7_+_93373755 0.023 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_-_178461710 0.022 NM_001077196
PDE11A
phosphodiesterase 11A
chr15_-_86890796 0.021 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr17_-_61655915 0.021 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_94250357 0.021 MCTP1
multiple C2 domains, transmembrane 1
chr10_+_104493701 0.020 C10orf26
chromosome 10 open reading frame 26
chr10_+_95507555 0.020 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr11_+_64949365 0.020 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_116580892 0.020 TAGLN
transgelin
chr11_+_94398069 0.019 NM_001161630
KDM4DL
lysine (K)-specific demethylase 4D-like
chr14_+_18447521 0.018 NM_001013354
OR11H12
olfactory receptor, family 11, subfamily H, member 12
chr3_-_25658829 0.018 TOP2B
topoisomerase (DNA) II beta 180kDa
chr8_-_107023 0.018 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr2_-_152538694 0.018 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr3_+_159310631 0.018 RSRC1
arginine/serine-rich coiled-coil 1
chr4_-_2200755 0.018 NM_181808
POLN
polymerase (DNA directed) nu
chr6_+_116956868 0.018 NM_153036
FAM26D
family with sequence similarity 26, member D
chr12_+_50342814 0.017 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_106248706 0.017 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr10_-_93992982 0.017 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr13_+_30207668 0.017 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr20_-_33705244 0.016 NM_003915
CPNE1
copine I
chr5_+_60969392 0.016 NM_173667
FLJ37543
hypothetical protein FLJ37543
chrX_+_30158473 0.016 NM_002365
MAGEB3
melanoma antigen family B, 3
chr3_-_42427026 0.015 NM_144634
LYZL4
lysozyme-like 4
chr3_+_161040439 0.015 SCHIP1
schwannomin interacting protein 1
chr6_+_27400518 0.015 NM_032030
FKSG83
FKSG83
chr18_-_29273979 0.014 NM_001105528
C18orf34
chromosome 18 open reading frame 34
chr11_+_60223622 0.014 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr18_-_29882555 0.014 NM_001198549
NOL4
nucleolar protein 4
chr2_+_204509698 0.014 NM_012092
ICOS
inducible T-cell co-stimulator
chr5_-_145503190 0.013 LARS
leucyl-tRNA synthetase
chr15_+_36014748 0.013 NM_152453
TMCO5A
transmembrane and coiled-coil domains 5A
chr11_-_57964221 0.013 NM_001004733
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr12_+_73217817 0.013 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr11_+_59902530 0.012 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr1_-_147665783 0.012 HIST2H2BF
histone cluster 2, H2bf
chr2_+_108230082 0.012 NM_001008743
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr6_+_155579788 0.012 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr18_-_62422195 0.012 NM_021153
CDH19
cadherin 19, type 2
chr2_+_69055208 0.011 NM_019617
GKN1
gastrokine 1
chr4_+_187424111 0.011 NM_000128
F11
coagulation factor XI
chr8_+_17866373 0.011 PCM1
pericentriolar material 1
chr12_+_14429499 0.011 ATF7IP
activating transcription factor 7 interacting protein
chr11_+_55407348 0.011 NM_032681
SPRYD5
SPRY domain containing 5
chr7_+_113853790 0.010 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr17_-_77469280 0.010 SIRT7
sirtuin 7
chr8_-_15140162 0.010 NM_139167
SGCZ
sarcoglycan, zeta
chr21_+_30690165 0.010 NM_181599
KRTAP13-1
keratin associated protein 13-1
chr14_+_55148488 0.010 KTN1
kinectin 1 (kinesin receptor)
chr5_+_180726874 0.010 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr11_-_123799976 0.010 NM_001005196
OR8B4
olfactory receptor, family 8, subfamily B, member 4
chr6_+_31081707 0.010 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr10_-_98326435 0.009 TM9SF3
transmembrane 9 superfamily member 3
chr9_+_124172644 0.009 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_98646367 0.008 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chrX_-_117003310 0.008 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr13_+_50813168 0.008 NM_001101320
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr1_+_204797079 0.008 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr4_-_82345224 0.007 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr3_+_46894239 0.007 NM_000316
PTH1R
parathyroid hormone 1 receptor
chrX_+_10084984 0.006 NM_001830
CLCN4
chloride channel 4
chr1_-_245942679 0.006 NM_001005286
OR6F1
olfactory receptor, family 6, subfamily F, member 1
chr6_-_32268615 0.005 GPSM3
G-protein signaling modulator 3
chr17_+_65009986 0.005 MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_144374513 0.005 RNF115
ring finger protein 115
chr12_-_11354620 0.005 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr5_+_121493113 0.003 NM_207317
ZNF474
zinc finger protein 474
chr1_+_117098579 0.003 NM_001767
CD2
CD2 molecule
chr10_-_98280299 0.002 TM9SF3
transmembrane 9 superfamily member 3
chr16_+_29971971 0.002 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr12_+_124377114 0.002 NM_052907
TMEM132B
transmembrane protein 132B
chr11_-_56166490 0.001 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr2_-_61098867 0.001 NM_144709
PUS10
pseudouridylate synthase 10

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.34 4.49e-04 GO:0007606 sensory perception of chemical stimulus
4.24 2.97e-03 GO:0007608 sensory perception of smell

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.44 4.42e-04 GO:0004984 olfactory receptor activity
2.71 1.48e-02 GO:0004930 G-protein coupled receptor activity
2.29 2.01e-02 GO:0004888 transmembrane receptor activity