Motif ID: DBP.p2

Z-value: 1.576


Transcription factors associated with DBP.p2:

Gene SymbolEntrez IDGene Name
DBP 1628 D site of albumin promoter (albumin D-box) binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
DBPchr19_-_538323810.029.5e-01Click!


Activity profile for motif DBP.p2.

activity profile for motif DBP.p2


Sorted Z-values histogram for motif DBP.p2

Sorted Z-values for motif DBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_50342814 1.218 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr2_-_189752575 1.176 NM_000393
COL5A2
collagen, type V, alpha 2
chr14_-_72430545 1.136 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr1_+_114323552 1.112 NM_020190
OLFML3
olfactomedin-like 3
chr7_+_120416680 1.102 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr17_-_44006808 1.093 NM_002146
HOXB3
homeobox B3
chr4_-_159313613 1.074 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr15_-_88150823 1.071 ANPEP
alanyl (membrane) aminopeptidase
chr1_+_221168388 1.047 NM_032890
DISP1
dispatched homolog 1 (Drosophila)
chr4_-_186969202 1.042 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186969041 1.000 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr1_-_53972464 0.982 NM_147193
GLIS1
GLIS family zinc finger 1
chr18_-_21184824 0.969


chr1_+_84382529 0.964 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_36533903 0.959 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr1_-_171442937 0.944 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr12_-_90029328 0.931 LUM
lumican
chr12_-_90029672 0.918 NM_002345
LUM
lumican
chr6_+_45404031 0.914 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr11_-_85107569 0.906 NM_206929
SYTL2
synaptotagmin-like 2
chr9_+_18464090 0.901 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr3_+_8750485 0.882 NM_033337
NM_001234
CAV3

caveolin 3

chr5_-_151764857 0.862 NM_020167
NMUR2
neuromedin U receptor 2
chr4_-_23500706 0.859 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr10_+_685887 0.859 C10orf108
chromosome 10 open reading frame 108
chr10_+_97749837 0.844 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr2_-_192419896 0.843 SDPR
serum deprivation response
chr3_-_148604760 0.838 NM_001168378
ZIC4
Zic family member 4
chr12_+_99391681 0.813 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr6_-_117853710 0.809 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr4_-_159312973 0.807 FAM198B
family with sequence similarity 198, member B
chr18_-_63333487 0.805 DSEL
dermatan sulfate epimerase-like
chr11_+_112337411 0.804 NCAM1
neural cell adhesion molecule 1
chr1_+_103961476 0.792 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr17_-_44037332 0.789 NM_018952
HOXB6
homeobox B6
chrX_+_77889861 0.783 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr8_-_68821131 0.780 NM_020361
CPA6
carboxypeptidase A6
chr5_+_71538456 0.772 MAP1B
microtubule-associated protein 1B
chr18_-_21185968 0.761 ZNF521
zinc finger protein 521
chr11_-_4346191 0.745 NM_001005161
OR52B4
olfactory receptor, family 52, subfamily B, member 4
chr3_-_150578023 0.732 TM4SF1
transmembrane 4 L six family member 1
chr4_+_87070449 0.727 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr9_-_94226380 0.720 NM_005014
OMD
osteomodulin
chr15_-_31147376 0.719 NM_001103184
FMN1
formin 1
chr16_+_85169615 0.715 NM_005250
FOXL1
forkhead box L1
chr11_+_112337491 0.707 NCAM1
neural cell adhesion molecule 1
chr12_+_99391870 0.701 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr10_-_60792225 0.697 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr18_-_21186107 0.695 NM_015461
ZNF521
zinc finger protein 521
chr1_-_39871226 0.694 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr15_+_78520634 0.691 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr15_+_30797466 0.684 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr11_+_112337299 0.674 NCAM1
neural cell adhesion molecule 1
chr2_-_180319013 0.674 NM_001113397
ZNF385B
zinc finger protein 385B
chr3_-_113842133 0.673 CCDC80
coiled-coil domain containing 80
chr7_+_128257698 0.671 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr12_-_119249938 0.668 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr2_-_144994038 0.662 ZEB2
zinc finger E-box binding homeobox 2
chr9_+_18464138 0.660 ADAMTSL1
ADAMTS-like 1
chr9_-_35948150 0.657 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr6_+_136214495 0.657 NM_018945
PDE7B
phosphodiesterase 7B
chr10_-_31328426 0.654 NM_001143769
ZNF438
zinc finger protein 438
chr9_-_74757735 0.652 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr3_-_115826481 0.651 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_25135783 0.651 NM_001169
AQP8
aquaporin 8
chr9_-_124280025 0.649 NM_001004451
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr4_+_54790020 0.646 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr19_+_43616167 0.641 NM_000540
NM_001042723
RYR1

ryanodine receptor 1 (skeletal)

chr4_-_159313167 0.641 NM_016613
FAM198B
family with sequence similarity 198, member B
chr5_+_137447479 0.637 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr2_-_144991386 0.636 ZEB2
zinc finger E-box binding homeobox 2
chr12_+_6884157 0.634 NM_001135217
NM_006992
NM_201650
LRRC23


leucine rich repeat containing 23


chr6_+_131190237 0.629 NM_001195597
LOC285733
hypothetical LOC285733
chr3_-_113842350 0.628 CCDC80
coiled-coil domain containing 80
chr11_+_110631916 0.626 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr1_+_213245507 0.625 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr7_+_134226690 0.620 NM_033139
NM_033140
CALD1

caldesmon 1

chr11_+_113672407 0.620 NNMT
nicotinamide N-methyltransferase
chr12_-_54392328 0.609 NM_001144997
ITGA7
integrin, alpha 7
chr4_-_16509354 0.607 LDB2
LIM domain binding 2
chr1_+_84382562 0.607 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_90100733 0.598 NM_001920
DCN
decorin
chr3_-_150578103 0.596 TM4SF1
transmembrane 4 L six family member 1
chr3_-_113842255 0.595 CCDC80
coiled-coil domain containing 80
chr1_-_220788048 0.590 NM_024746
HHIPL2
HHIP-like 2
chr17_+_45598363 0.589 NM_000023
NM_001135697
SGCA

sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)

chr7_-_135083906 0.584 NM_205855
FAM180A
family with sequence similarity 180, member A
chr2_+_66519949 0.583 MEIS1
Meis homeobox 1
chr15_+_64782468 0.583 SMAD6
SMAD family member 6
chr20_+_54420574 0.580 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr7_+_142629251 0.576 NM_176882
TAS2R40
taste receptor, type 2, member 40
chr4_+_81337663 0.572 NM_001099403
PRDM8
PR domain containing 8
chr11_+_112337199 0.562 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr9_+_117955890 0.559 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_-_90100679 0.559 DCN
decorin
chr4_+_41234944 0.559 LIMCH1
LIM and calponin homology domains 1
chr17_-_44022595 0.558 HOXB3
homeobox B3
chr5_-_39430180 0.553 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_-_90100710 0.551 DCN
decorin
chr2_-_190635566 0.546 NM_005259
MSTN
myostatin
chr8_-_67253234 0.546 NM_000756
CRH
corticotropin releasing hormone
chr4_-_159311959 0.543 FAM198B
family with sequence similarity 198, member B
chr5_-_95184221 0.534 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr4_+_88973144 0.529 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr3_+_35696119 0.528 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr5_-_95184121 0.527 GLRX
glutaredoxin (thioltransferase)
chr5_+_176449156 0.527 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr7_-_75876830 0.525 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr8_+_106400322 0.524 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr3_-_52454082 0.517 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr14_-_36121536 0.513 NM_014360
NKX2-8
NK2 homeobox 8
chr3_+_100840129 0.508 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr1_+_84382575 0.504 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_+_56888588 0.501 NM_018488
TBX4
T-box 4
chr3_-_113842237 0.498 CCDC80
coiled-coil domain containing 80
chr17_-_7023378 0.496 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr4_+_54790190 0.495 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr6_+_88111289 0.492 NM_001010868
C6orf163
chromosome 6 open reading frame 163
chr1_+_162795538 0.489 PBX1
pre-B-cell leukemia homeobox 1
chr11_-_85103438 0.486 NM_032379
SYTL2
synaptotagmin-like 2
chr7_+_143437539 0.482 NM_001005480
OR2A2
olfactory receptor, family 2, subfamily A, member 2
chr13_+_97856148 0.480


chr11_+_48466844 0.480 NM_001005512
OR4A47
olfactory receptor, family 4, subfamily A, member 47
chr4_+_114433551 0.478 ANK2
ankyrin 2, neuronal
chr3_-_188935363 0.476 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr8_-_124818754 0.469 NM_001003954
NM_004306
ANXA13

annexin A13

chr12_-_54522881 0.466 NM_002429
MMP19
matrix metallopeptidase 19
chr17_+_36493927 0.464 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr6_-_119512035 0.464 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr8_-_20156971 0.463 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr1_+_84402962 0.461 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_72673753 0.456 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr5_-_95794416 0.453 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr5_-_27074407 0.449 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr3_-_38810504 0.448 NM_006514
SCN10A
sodium channel, voltage-gated, type X, alpha subunit
chr1_-_143075560 0.448 NM_178230
NM_001143883
NM_001135789
PPIAL4A
PPIAL4G
PPIAL4B
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4G
peptidylprolyl isomerase A (cyclophilin A)-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr9_-_14388981 0.447 NM_001190738
NFIB
nuclear factor I/B
chr11_+_20000938 0.443 NAV2
neuron navigator 2
chr10_+_52504239 0.443 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr22_-_16127520 0.440 CECR3
cat eye syndrome chromosome region, candidate 3
chr13_+_57103789 0.439 NM_001040429
PCDH17
protocadherin 17
chr1_-_201321711 0.434 MYOG
myogenin (myogenic factor 4)
chr4_-_24590867 0.433 NM_173463
CCDC149
coiled-coil domain containing 149
chr7_+_134226727 0.432 CALD1
caldesmon 1
chr1_-_161380562 0.432 RGS5
regulator of G-protein signaling 5
chr13_+_22653059 0.431 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr7_+_100557098 0.431 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_-_194844061 0.430 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr9_-_13240313 0.429 NM_003829
MPDZ
multiple PDZ domain protein
chr9_-_21207303 0.427 NM_002173
IFNA16
interferon, alpha 16
chr1_-_201411533 0.427 NM_004997
MYBPH
myosin binding protein H
chr1_-_149611768 0.424 NM_003944
SELENBP1
selenium binding protein 1
chr17_-_44026321 0.424 HOXB5
homeobox B5
chr2_-_144991556 0.424 ZEB2
zinc finger E-box binding homeobox 2
chr2_-_144994349 0.422 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chrX_-_77801480 0.420 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr16_-_88623809 0.420 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr7_+_120416103 0.419 C7orf58
chromosome 7 open reading frame 58
chr3_+_139211639 0.419 NM_016369
CLDN18
claudin 18
chr7_-_124217978 0.419 NM_001024603
LOC154872
hypothetical protein LOC154872
chr5_-_55564942 0.419 NM_024669
ANKRD55
ankyrin repeat domain 55
chrX_+_10084984 0.417 NM_001830
CLCN4
chloride channel 4
chr11_+_72660894 0.417 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr4_-_16509126 0.416 LDB2
LIM domain binding 2
chr10_+_50177192 0.415 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr5_-_58331515 0.415 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_90731671 0.413 NM_003505
FZD1
frizzled homolog 1 (Drosophila)
chr10_-_56230953 0.413 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr10_+_11087280 0.412 CELF2
CUGBP, Elav-like family member 2
chr21_+_29439768 0.412 C21orf7
chromosome 21 open reading frame 7
chr2_+_108360798 0.411 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr4_+_159662349 0.410 NM_021634
RXFP1
relaxin/insulin-like family peptide receptor 1
chr17_-_43977273 0.408 NM_002145
HOXB2
homeobox B2
chr13_+_92677012 0.407 NM_005708
GPC6
glypican 6
chr4_+_154345039 0.407 NM_015271
TRIM2
tripartite motif containing 2
chr5_+_54491702 0.405 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr4_-_138673014 0.403 PCDH18
protocadherin 18
chr16_+_31105579 0.401


chr5_-_39460787 0.401 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr9_-_83494198 0.400 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr3_-_147361626 0.399 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr18_+_30651923 0.397 NM_001198943
DTNA
dystrobrevin, alpha
chr20_-_218957 0.394 C20orf96
chromosome 20 open reading frame 96
chr2_-_215955206 0.393 FN1
fibronectin 1
chr9_-_14769530 0.391 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr6_+_26153590 0.391 NM_003531
HIST1H3C
histone cluster 1, H3c
chr1_+_203503214 0.390 TMCC2
transmembrane and coiled-coil domain family 2
chr1_+_146910634 0.390 NM_001144032
PPIAL4E
peptidylprolyl isomerase A (cyclophilin A)-like 4E
chr19_+_614381 0.387


chr4_-_138673078 0.386 NM_019035
PCDH18
protocadherin 18
chr10_-_100985548 0.382 NM_001166244
NM_001166245
NM_001166246
NM_021828
HPSE2



heparanase 2



chr15_+_66711380 0.381 NM_001190457
CORO2B
coronin, actin binding protein, 2B
chr2_+_166137091 0.380 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_-_69434650 0.379 PTPRR
protein tyrosine phosphatase, receptor type, R
chrX_+_66705407 0.378 NM_001011645
AR
androgen receptor
chr2_+_157822355 0.375 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_-_55460451 0.375 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr21_+_44941514 0.373 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr3_+_171621721 0.372 NM_001185056
CLDN11
claudin 11
chr4_+_120276386 0.372 NM_016599
MYOZ2
myozenin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 7.06e-12 GO:0032501 multicellular organismal process
1.32 1.65e-09 GO:0032502 developmental process
1.33 3.50e-09 GO:0007275 multicellular organismal development
1.37 6.59e-09 GO:0048731 system development
1.54 1.03e-08 GO:0007399 nervous system development
1.32 1.25e-07 GO:0048856 anatomical structure development
1.38 5.18e-06 GO:0030154 cell differentiation
1.37 7.08e-06 GO:0048869 cellular developmental process
1.78 6.49e-05 GO:0007417 central nervous system development
1.35 2.58e-04 GO:0048513 organ development
1.91 7.77e-04 GO:0060284 regulation of cell development
1.34 2.04e-03 GO:0003008 system process
2.14 2.28e-03 GO:0007517 muscle organ development
2.07 5.78e-03 GO:0045664 regulation of neuron differentiation
2.34 6.57e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.45 6.87e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.77 8.43e-03 GO:0007420 brain development
1.54 8.51e-03 GO:0009790 embryo development
1.46 1.08e-02 GO:0022008 neurogenesis
1.35 1.17e-02 GO:0009653 anatomical structure morphogenesis
1.47 1.49e-02 GO:0048699 generation of neurons
1.46 2.07e-02 GO:0040011 locomotion
2.25 2.26e-02 GO:0001503 ossification
1.79 2.72e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.51 3.51e-02 GO:0010628 positive regulation of gene expression
1.89 3.53e-02 GO:0003002 regionalization
1.61 3.80e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
4.27 3.95e-02 GO:0016441 posttranscriptional gene silencing
4.27 3.95e-02 GO:0035194 posttranscriptional gene silencing by RNA
1.86 4.28e-02 GO:0050767 regulation of neurogenesis
1.47 4.79e-02 GO:0007267 cell-cell signaling
1.53 4.89e-02 GO:0009887 organ morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.57 1.11e-03 GO:0030054 cell junction
1.28 1.95e-03 GO:0005576 extracellular region
1.69 2.04e-03 GO:0045202 synapse
2.17 2.04e-03 GO:0045211 postsynaptic membrane
1.18 3.05e-03 GO:0005886 plasma membrane
1.68 4.48e-03 GO:0031012 extracellular matrix
1.17 4.60e-03 GO:0071944 cell periphery
1.39 4.74e-03 GO:0044421 extracellular region part
2.16 2.59e-02 GO:0030016 myofibril
1.67 2.84e-02 GO:0005578 proteinaceous extracellular matrix
1.68 3.63e-02 GO:0044456 synapse part
1.22 4.04e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.51 2.62e-05 GO:0030528 transcription regulator activity
6.95 4.86e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
1.33 2.70e-02 GO:0004888 transmembrane receptor activity