Motif ID: IRF1,2,7.p3

Z-value: 4.882


Transcription factors associated with IRF1,2,7.p3:

Gene SymbolEntrez IDGene Name
IRF1 3659 interferon regulatory factor 1
IRF2 3660 interferon regulatory factor 2
IRF7 3665 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IRF2chr4_-_1856326100.448.9e-02Click!
IRF1chr5_-_1318543250.439.4e-02Click!
IRF7chr11_-_6059200.253.6e-01Click!


Activity profile for motif IRF1,2,7.p3.

activity profile for motif IRF1,2,7.p3


Sorted Z-values histogram for motif IRF1,2,7.p3

Sorted Z-values for motif IRF1,2,7.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of IRF1,2,7.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_78858675 10.476 NM_006820
IFI44L
interferon-induced protein 44-like
chr12_+_111900650 8.604 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr10_+_91077581 5.910 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr21_+_41655786 5.343 NM_002463
LOC100131190
MX2
hypothetical protein LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr12_+_25096755 5.249 LRMP
lymphoid-restricted membrane protein
chr10_+_91082218 4.866 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91142301 4.410 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_-_27871306 3.911 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr1_-_27871287 3.858 IFI6
interferon, alpha-inducible protein 6
chr1_-_27871245 3.805 IFI6
interferon, alpha-inducible protein 6
chr17_-_37518213 3.721 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr22_+_17012841 3.560 USP18
ubiquitin specific peptidase 18
chr1_+_938709 3.542 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr7_+_73826244 3.532 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr4_+_142777172 3.421 NM_000585
NM_172174
IL15

interleukin 15

chr22_+_17012704 3.393 NM_017414
USP18
ubiquitin specific peptidase 18
chr19_-_7672978 3.283 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr12_+_93066370 3.243 NM_005761
PLXNC1
plexin C1
chr1_+_78888064 3.170 NM_006417
IFI44
interferon-induced protein 44
chr7_+_150013716 3.136 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr1_+_157246305 3.131 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr12_+_111860609 3.030 NM_006187
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr10_+_91051685 2.963 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr4_-_40212670 2.952 NM_019027
RBM47
RNA binding motif protein 47
chr21_+_41714311 2.945 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr4_+_89519134 2.918 HERC6
hect domain and RLD 6
chr3_+_188568861 2.914 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr7_-_92615593 2.852 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr11_+_5667392 2.847 TRIM22
tripartite motif containing 22
chr4_+_89597257 2.812 NM_016323
HERC5
hect domain and RLD 5
chr6_-_31432543 2.794 HLA-B
major histocompatibility complex, class I, B
chr12_+_25096472 2.773 NM_006152
LRMP
lymphoid-restricted membrane protein
chr12_+_111860384 2.772 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr5_-_95184121 2.770 GLRX
glutaredoxin (thioltransferase)
chr22_-_34886727 2.722 NM_145640
APOL3
apolipoprotein L, 3
chr1_-_9052207 2.720 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr13_-_42464301 2.714 NM_001002264
NM_033255
EPSTI1

epithelial stromal interaction 1 (breast)

chr16_-_66528152 2.705 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr16_-_66528235 2.686 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_111860684 2.665 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr3_+_114733907 2.592 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr6_+_32929902 2.555 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr17_+_6600080 2.514 XAF1
XIAP associated factor 1
chr12_+_111829121 2.507 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr15_+_86983038 2.424 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_-_230792844 2.400 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr5_-_95184221 2.334 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr17_+_6599879 2.290 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr6_-_32929390 2.247 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_37081387 2.213 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr6_+_6533932 2.175 NM_004271
LY86
lymphocyte antigen 86
chr3_-_173723754 2.166 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr9_+_5440455 2.153 NM_014143
CD274
CD274 molecule
chr7_-_149960218 2.145 GIMAP6
GTPase, IMAP family member 6
chr6_-_32919751 2.112 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr16_+_55580910 2.112 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr1_+_157067729 2.110 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr4_+_37569093 2.107 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_7463175 2.105 NM_198474
OLFML1
olfactomedin-like 1
chr22_+_34374358 2.088 NM_030641
APOL6
apolipoprotein L, 6
chr1_-_2486313 2.071 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr19_-_18058632 2.052 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr6_+_26548678 2.048 NM_006994
NM_197974
BTN3A3

butyrophilin, subfamily 3, member A3

chr15_-_42790805 2.040


chr17_+_44643067 2.035 ABI3
ABI family, member 3
chr22_+_34979118 2.031 APOL1
apolipoprotein L, 1
chr11_-_60475558 2.001 NM_016582
SLC15A3
solute carrier family 15, member 3
chr1_-_89303478 1.943 NM_002053
GBP1
guanylate binding protein 1, interferon-inducible, 67kDa
chr1_-_25164061 1.909 NM_001031680
RUNX3
runt-related transcription factor 3
chr9_-_32516164 1.905 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_128367961 1.903 NM_001098627
IRF5
interferon regulatory factor 5
chr5_-_156322784 1.898 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr5_+_131774478 1.897 NM_001013717
C5orf56
chromosome 5 open reading frame 56
chr17_-_44642934 1.875 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr6_+_116889248 1.869 NM_001010919
FAM26F
family with sequence similarity 26, member F
chr17_+_69974361 1.866 CD300A
CD300a molecule
chr9_+_5500544 1.861 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr5_+_156628929 1.834 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr6_-_32929570 1.820 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr20_-_24986501 1.787 ACSS1
acyl-CoA synthetase short-chain family member 1
chr20_+_44180355 1.775 CD40
CD40 molecule, TNF receptor superfamily member 5
chr12_+_8167494 1.760 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chr10_+_11087280 1.754 CELF2
CUGBP, Elav-like family member 2
chr13_+_48968097 1.743 PHF11
PHD finger protein 11
chr3_+_123882355 1.732 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr3_-_49826360 1.724 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr9_-_21067804 1.723 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr16_+_10878539 1.723 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr3_-_49826221 1.723 UBA7
ubiquitin-like modifier activating enzyme 7
chr22_+_34979062 1.702 NM_001136540
NM_001136541
NM_003661
NM_145343
APOL1



apolipoprotein L, 1



chr6_-_133126278 1.699 NM_078488
VNN2
vanin 2
chr6_-_30289092 1.683 NM_003449
TRIM26
tripartite motif containing 26
chr21_+_41719847 1.654 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr13_+_48968528 1.648 NM_001040444
PHF11
PHD finger protein 11
chr12_+_6431437 1.647 NM_018009
TAPBPL
TAP binding protein-like
chr16_+_29739256 1.635 MVP
major vault protein
chr17_-_30783631 1.630 NM_018042
SLFN12
schlafen family member 12
chr6_-_32929721 1.628 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_25982418 1.616 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr6_+_26510443 1.615 NM_001145008
NM_001145009
NM_007048
NM_194441
BTN3A1



butyrophilin, subfamily 3, member A1



chr16_-_49272617 1.615 SNX20
sorting nexin 20
chr2_+_230989150 1.614 SP100
SP100 nuclear antigen
chr11_-_57091656 1.595 NM_004223
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr1_-_159306369 1.563 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr2_+_61243132 1.547 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr22_+_34374421 1.536 APOL6
apolipoprotein L, 6
chrX_+_37524190 1.518 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr9_-_35802142 1.508 NM_001039592
NM_172312
SPAG8

sperm associated antigen 8

chr12_+_100795480 1.493 DRAM1
DNA-damage regulated autophagy modulator 1
chr2_-_6923215 1.474 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_12149637 1.466 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr1_-_9052170 1.464 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chrX_+_37524250 1.457 CYBB
cytochrome b-245, beta polypeptide
chr9_-_21375258 1.452 NM_000605
IFNA2
interferon, alpha 2
chr12_-_9913724 1.445 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr7_-_92585253 1.420 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr1_-_89261021 1.417 NM_018284
GBP3
guanylate binding protein 3
chr17_+_69974375 1.409 CD300A
CD300a molecule
chr4_-_38460983 1.397 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr11_+_5602782 1.396 NM_021616
TRIM34
tripartite motif containing 34
chr2_+_68445821 1.387 NM_002664
PLEK
pleckstrin
chr1_-_9052253 1.369 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr1_-_159306327 1.366 ARHGAP30
Rho GTPase activating protein 30
chr10_+_92970302 1.333 NM_032373
PCGF5
polycomb group ring finger 5
chr6_+_26473376 1.331 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr13_-_33148899 1.323 STARD13
StAR-related lipid transfer (START) domain containing 13
chr14_-_69953433 1.322 NM_018373
SYNJ2BP
synaptojanin 2 binding protein
chr3_-_115825742 1.315 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_11694172 1.304 ETV6
ets variant 6
chr22_-_16080265 1.304 CECR1
cat eye syndrome chromosome region, candidate 1
chrX_+_80344253 1.301 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr17_+_22982344 1.290 LGALS9
lectin, galactoside-binding, soluble, 9
chr9_-_21177529 1.288 NM_021068
IFNA4
interferon, alpha 4
chrX_+_38096679 1.288 NM_000531
OTC
ornithine carbamoyltransferase
chr13_-_29321599 1.284 UBL3
ubiquitin-like 3
chr2_-_227737009 1.282 COL4A4
collagen, type IV, alpha 4
chr7_-_92585205 1.281 SAMD9
sterile alpha motif domain containing 9
chrX_+_14457340 1.279 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr17_+_22982319 1.277 LGALS9
lectin, galactoside-binding, soluble, 9
chr10_+_63478974 1.274 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr16_-_49272741 1.274 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr4_-_169476391 1.270 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr10_-_6059460 1.267 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr17_+_22982383 1.263 LGALS9
lectin, galactoside-binding, soluble, 9
chr8_-_145132582 1.261 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr6_+_32713160 1.257 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr17_+_22982372 1.252 LGALS9
lectin, galactoside-binding, soluble, 9
chr6_-_110843432 1.243 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr2_-_191587169 1.242 NM_007315
NM_139266
STAT1

signal transducer and activator of transcription 1, 91kDa

chr5_-_149772563 1.239 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chrX_+_56772391 1.237 LOC550643
hypothetical LOC550643
chr12_+_54011750 1.235 NM_054104
OR6C3
olfactory receptor, family 6, subfamily C, member 3
chr10_+_97461525 1.234 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr19_+_6838576 1.232 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr5_-_149772469 1.225 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr12_+_12115668 1.218 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr10_+_92970487 1.215 PCGF5
polycomb group ring finger 5
chr3_+_120904555 1.213 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr17_+_44642587 1.212 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr19_+_55124211 1.208 NM_001193646
ATF5
activating transcription factor 5
chr17_-_35328368 1.207 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr2_+_33555182 1.201 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_+_91164283 1.190 NM_012420
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr17_+_22982278 1.188 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr3_-_123766113 1.177 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr3_-_123765767 1.168 NM_001146102
NM_001146105
NM_001146104
NM_001146106
PARP9



poly (ADP-ribose) polymerase family, member 9



chr2_+_230798687 1.162 NM_001005176
NM_007237
SP140

SP140 nuclear body protein

chr18_+_59726183 1.161 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_208568811 1.157 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr8_-_145132551 1.157 PARP10
poly (ADP-ribose) polymerase family, member 10
chr12_+_29267863 1.154 NM_018099
FAR2
fatty acyl CoA reductase 2
chr11_-_107087943 1.147 NM_003063
SLN
sarcolipin
chr11_+_1830763 1.137 NM_002339
LSP1
lymphocyte-specific protein 1
chr11_-_605920 1.118 IRF7
interferon regulatory factor 7
chr19_+_10058023 1.110 C19orf66
chromosome 19 open reading frame 66
chr17_+_69974116 1.108 NM_007261
CD300A
CD300a molecule
chr6_+_31648071 1.108 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr2_-_225519974 1.100 DOCK10
dedicator of cytokinesis 10
chr6_-_152542293 1.100 NM_133650
SYNE1
spectrin repeat containing, nuclear envelope 1
chr19_+_10057972 1.088 C19orf66
chromosome 19 open reading frame 66
chr2_+_33554824 1.085 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_+_44180296 1.075 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr7_-_76883642 1.070 NM_017439
PION
pigeon homolog (Drosophila)
chr1_-_13546097 1.068 NM_001024661
NM_001099854
PRAMEF13
PRAMEF14
PRAME family member 13
PRAME family member 14
chrX_+_80343958 1.064 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr5_-_169340321 1.056 NM_001129891
FAM196B
family with sequence similarity 196, member B
chr19_-_6393004 1.055 SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr22_+_37802955 1.048 NM_021822
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr2_+_68445936 1.041 PLEK
pleckstrin
chr10_+_97505398 1.038 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr3_-_115960807 1.026 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr22_+_36008465 1.017 CYTH4
cytohesin 4
chr2_-_191587127 1.011 STAT1
signal transducer and activator of transcription 1, 91kDa
chr5_-_135729062 1.008 NM_001167576
NM_001167577
NM_020389
TRPC7


transient receptor potential cation channel, subfamily C, member 7


chr22_+_37747063 1.006 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr16_+_56134077 1.001 NM_153837
GPR114
G protein-coupled receptor 114
chr2_-_191587153 1.001 STAT1
signal transducer and activator of transcription 1, 91kDa
chr18_+_46659484 0.986 ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr4_-_157094443 0.981 NM_001334
CTSO
cathepsin O
chr6_-_27948065 0.978 NM_003533
HIST1H3I
histone cluster 1, H3i

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
9.10 5.48e-24 GO:0060337 type I interferon-mediated signaling pathway
9.10 5.48e-24 GO:0071357 cellular response to type I interferon
8.96 1.20e-23 GO:0034340 response to type I interferon
3.49 3.00e-19 GO:0045087 innate immune response
2.62 1.22e-18 GO:0006955 immune response
2.20 1.48e-18 GO:0002376 immune system process
4.43 3.80e-17 GO:0019221 cytokine-mediated signaling pathway
4.15 1.90e-16 GO:0071345 cellular response to cytokine stimulus
4.58 3.50e-15 GO:0009615 response to virus
2.28 7.97e-13 GO:0006952 defense response
3.27 8.00e-13 GO:0034097 response to cytokine stimulus
8.36 1.01e-08 GO:0060338 regulation of type I interferon-mediated signaling pathway
2.52 4.82e-08 GO:0051707 response to other organism
2.43 7.31e-08 GO:0050776 regulation of immune response
2.33 8.26e-08 GO:0009607 response to biotic stimulus
2.70 1.09e-07 GO:0031347 regulation of defense response
1.96 1.12e-07 GO:0051704 multi-organism process
3.34 2.64e-07 GO:0045088 regulation of innate immune response
2.06 5.76e-07 GO:0002682 regulation of immune system process
2.10 7.31e-07 GO:0071310 cellular response to organic substance
1.25 1.13e-05 GO:0050896 response to stimulus
4.81 1.25e-05 GO:0001959 regulation of cytokine-mediated signaling pathway
8.62 1.61e-05 GO:0048002 antigen processing and presentation of peptide antigen
4.73 1.68e-05 GO:0060759 regulation of response to cytokine stimulus
2.13 1.91e-05 GO:0080134 regulation of response to stress
1.45 3.09e-05 GO:0006950 response to stress
3.92 2.27e-04 GO:0034341 response to interferon-gamma
2.25 2.70e-04 GO:0044419 interspecies interaction between organisms
1.73 3.45e-04 GO:0070887 cellular response to chemical stimulus
4.15 3.87e-04 GO:0071346 cellular response to interferon-gamma
9.65 6.20e-04 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
13.44 1.06e-03 GO:0019883 antigen processing and presentation of endogenous antigen
1.45 2.17e-03 GO:0048583 regulation of response to stimulus
1.31 2.31e-03 GO:0007165 signal transduction
4.57 2.55e-03 GO:0032479 regulation of type I interferon production
4.05 2.73e-03 GO:0060333 interferon-gamma-mediated signaling pathway
4.28 2.73e-03 GO:0019882 antigen processing and presentation
2.00 3.35e-03 GO:0002684 positive regulation of immune system process
2.90 5.18e-03 GO:0001819 positive regulation of cytokine production
2.15 5.69e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.26 5.85e-03 GO:0051716 cellular response to stimulus
2.10 9.39e-03 GO:0044257 cellular protein catabolic process
2.01 2.26e-02 GO:0030163 protein catabolic process
5.23 2.39e-02 GO:0032480 negative regulation of type I interferon production
1.16 2.54e-02 GO:0050789 regulation of biological process
1.26 2.97e-02 GO:0023052 signaling
1.40 3.12e-02 GO:0007166 cell surface receptor linked signaling pathway
1.74 3.27e-02 GO:0009057 macromolecule catabolic process
2.05 4.01e-02 GO:0019941 modification-dependent protein catabolic process
2.14 4.27e-02 GO:0001817 regulation of cytokine production
2.03 4.68e-02 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 9.16e-03 GO:0005737 cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.80 3.69e-05 GO:0005126 cytokine receptor binding
11.76 9.15e-04 GO:0005132 interferon-alpha/beta receptor binding
2.36 5.27e-03 GO:0005125 cytokine activity