Motif ID: TFEB.p2

Z-value: 1.439


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41781655-0.371.6e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_112999538 2.703 LAMP1
lysosomal-associated membrane protein 1
chr17_-_44043361 2.410 NM_004502
 HOXB7
homeobox B7
chr13_+_112999590 2.326 LAMP1
lysosomal-associated membrane protein 1
chr13_+_112999462 2.306 NM_005561
 LAMP1
lysosomal-associated membrane protein 1
chrX_-_100801472 2.027 NM_014782
NM_177949
 ARMCX2

armadillo repeat containing, X-linked 2

chr7_-_27162688 1.815 NM_006896
 HOXA7
homeobox A7
chr3_-_113763454 1.679 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr2_+_85834111 1.613 NM_032827
 ATOH8
atonal homolog 8 (Drosophila)
chr1_-_197173159 1.412 LOC100131234
familial acute myelogenous leukemia related factor
chrX_+_55760774 1.397 NM_006064
NM_016656
 RRAGB

Ras-related GTP binding B

chr17_-_7078399 1.378 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr1_-_68470585 1.372 NM_001002292
NM_001193334
NM_024911
 WLS


wntless homolog (Drosophila)


chr5_+_34692124 1.367 NM_001145522
NM_015577
 RAI14

retinoic acid induced 14

chr4_+_120167721 1.311 SYNPO2
synaptopodin 2
chr22_+_34107087 1.287 HMOX1
heme oxygenase (decycling) 1
chr8_-_95343716 1.257 NM_005261
NM_181702
 GEM

GTP binding protein overexpressed in skeletal muscle

chr8_-_95343696 1.248 GEM
GTP binding protein overexpressed in skeletal muscle
chr2_-_40510923 1.246 NM_001112800
NM_001112801
NM_021097
 SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr19_-_52710129 1.242 NM_003827
 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr9_-_16860719 1.204 NM_017637
 BNC2
basonuclin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
8.13 6.29e-05 GO:0007040 lysosome organization
7.32 2.29e-04 GO:0015682 ferric iron transport
7.32 2.29e-04 GO:0033572 transferrin transport
6.65 1.50e-06 GO:0007033 vacuole organization
5.99 2.25e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
5.99 2.25e-02 GO:0015991 ATP hydrolysis coupled proton transport
4.82 1.59e-03 GO:0048704 embryonic skeletal system morphogenesis
4.58 3.06e-03 GO:0006818 hydrogen transport
4.40 1.17e-02 GO:0015992 proton transport
4.04 3.31e-03 GO:0048706 embryonic skeletal system development
3.19 8.56e-03 GO:0048705 skeletal system morphogenesis
3.05 1.78e-02 GO:0008286 insulin receptor signaling pathway
2.85 1.93e-02 GO:0009952 anterior/posterior pattern formation
2.81 3.77e-02 GO:0048562 embryonic organ morphogenesis
2.56 1.62e-02 GO:0071375 cellular response to peptide hormone stimulus
2.47 5.78e-04 GO:0071495 cellular response to endogenous stimulus
2.37 6.08e-03 GO:0032870 cellular response to hormone stimulus
2.20 1.88e-04 GO:0034613 cellular protein localization
2.19 2.30e-04 GO:0070727 cellular macromolecule localization
2.19 6.15e-03 GO:0006886 intracellular protein transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
11.09 1.17e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
9.98 3.98e-06 GO:0033176 proton-transporting V-type ATPase complex
5.11 2.22e-03 GO:0016469 proton-transporting two-sector ATPase complex
4.92 1.21e-13 GO:0005774 vacuolar membrane
4.83 9.51e-14 GO:0044437 vacuolar part
4.51 2.56e-08 GO:0005765 lysosomal membrane
4.37 9.46e-04 GO:0031902 late endosome membrane
4.14 4.14e-20 GO:0005773 vacuole
3.73 3.50e-13 GO:0000323 lytic vacuole
3.73 3.50e-13 GO:0005764 lysosome
3.58 1.18e-04 GO:0005770 late endosome
3.05 1.06e-03 GO:0005769 early endosome
2.90 3.36e-06 GO:0010008 endosome membrane
2.88 4.16e-06 GO:0044440 endosomal part
2.41 1.39e-06 GO:0005768 endosome
1.70 1.23e-02 GO:0031410 cytoplasmic vesicle
1.69 2.58e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.67 1.73e-02 GO:0031982 vesicle
1.66 4.29e-02 GO:0031988 membrane-bounded vesicle
1.51 1.74e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
7.76 7.42e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
6.65 5.64e-04 GO:0019829 cation-transporting ATPase activity
3.76 1.63e-02 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
1.22 8.45e-05 GO:0005515 protein binding
1.11 8.49e-04 GO:0005488 binding