Motif ID: TFEB.p2

Z-value: 1.439


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41781655-0.371.6e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_112999538 2.703 LAMP1
lysosomal-associated membrane protein 1
chr17_-_44043361 2.410 NM_004502
HOXB7
homeobox B7
chr13_+_112999590 2.326 LAMP1
lysosomal-associated membrane protein 1
chr13_+_112999462 2.306 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chrX_-_100801472 2.027 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr7_-_27162688 1.815 NM_006896
HOXA7
homeobox A7
chr3_-_113763454 1.679 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr2_+_85834111 1.613 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_-_197173159 1.412 LOC100131234
familial acute myelogenous leukemia related factor
chrX_+_55760774 1.397 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr17_-_7078399 1.378 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr1_-_68470585 1.372 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr5_+_34692124 1.367 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr4_+_120167721 1.311 SYNPO2
synaptopodin 2
chr22_+_34107087 1.287 HMOX1
heme oxygenase (decycling) 1
chr8_-_95343716 1.257 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr8_-_95343696 1.248 GEM
GTP binding protein overexpressed in skeletal muscle
chr2_-_40510923 1.246 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr19_-_52710129 1.242 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr9_-_16860719 1.204 NM_017637
BNC2
basonuclin 2
chr8_-_71743908 1.190 LACTB2
lactamase, beta 2
chr15_-_38000379 1.188 NM_007223
GPR176
G protein-coupled receptor 176
chrX_-_34585287 1.184 NM_031442
TMEM47
transmembrane protein 47
chr13_-_95094920 1.184 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr5_+_34692239 1.175 RAI14
retinoic acid induced 14
chr17_-_7078446 1.164 NM_004422
DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr22_+_34107051 1.157 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr4_+_128870968 1.155 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr11_+_120399966 1.144 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr9_-_16860664 1.133 BNC2
basonuclin 2
chr17_+_3486753 1.130 CTNS
cystinosis, nephropathic
chr1_-_94475840 1.103 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr7_-_47588652 1.090 TNS3
tensin 3
chr1_-_32054164 1.083 NM_144569
SPOCD1
SPOC domain containing 1
chr2_+_223625105 1.061 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr3_-_113763449 1.055 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr4_+_120167770 1.051 SYNPO2
synaptopodin 2
chr5_+_34692352 1.048 NM_001145520
RAI14
retinoic acid induced 14
chr16_-_1341766 1.032 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr17_-_44042924 1.028 HOXB7
homeobox B7
chr10_-_14090459 1.023 FRMD4A
FERM domain containing 4A
chr7_-_47588160 1.006 TNS3
tensin 3
chr19_+_10625896 1.002 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr4_-_47160476 0.996 COMMD8
COMM domain containing 8
chr16_-_87450734 0.974 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr13_-_73605914 0.959 NM_007249
KLF12
Kruppel-like factor 12
chr2_+_219751145 0.950 NM_024293
FAM134A
family with sequence similarity 134, member A
chr16_+_31132842 0.939 NM_001008274
TRIM72
tripartite motif containing 72
chr1_+_216585298 0.935 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr19_+_5632139 0.927 HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr2_-_227372574 0.926 IRS1
insulin receptor substrate 1
chrX_-_100549444 0.922 GLA
galactosidase, alpha
chr8_-_71743973 0.922 NM_016027
LACTB2
lactamase, beta 2
chr8_+_133856738 0.918 NM_016018
NM_032205
NM_198513
PHF20L1


PHD finger protein 20-like 1


chr19_-_10625449 0.915 LOC147727
hypothetical LOC147727
chr2_+_187266899 0.895 NM_177454
FAM171B
family with sequence similarity 171, member B
chr17_-_7471832 0.887 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr3_+_108442205 0.878 LOC344595
hypothetical LOC344595
chr3_-_188946168 0.877 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr16_-_69277355 0.871 NM_138383
MTSS1L
metastasis suppressor 1-like
chr2_+_46779553 0.869 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr20_+_43953372 0.860 CTSA
cathepsin A
chr2_-_133144094 0.860 LYPD1
LY6/PLAUR domain containing 1
chr19_-_3451620 0.851 NM_031304
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr11_+_9642200 0.833 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr12_-_57600336 0.827 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr17_-_7078304 0.826 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr12_-_57600564 0.825 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr17_-_44026042 0.819 NM_002147
HOXB5
homeobox B5
chr3_+_129927714 0.810 RAB7A
RAB7A, member RAS oncogene family
chr1_+_201364050 0.805 ADORA1
adenosine A1 receptor
chr17_-_43977273 0.803 NM_002145
HOXB2
homeobox B2
chr11_+_9642226 0.799 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr2_-_196744546 0.799 NM_004226
STK17B
serine/threonine kinase 17b
chrX_+_102471769 0.797 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr3_+_129927668 0.789 NM_004637
RAB7A
RAB7A, member RAS oncogene family
chr11_-_36267510 0.785 COMMD9
COMM domain containing 9
chr11_+_9642182 0.783 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr1_-_201162991 0.780 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr3_+_129927723 0.777 RAB7A
RAB7A, member RAS oncogene family
chr2_+_219751192 0.773 FAM134A
family with sequence similarity 134, member A
chr3_+_129927716 0.768 RAB7A
RAB7A, member RAS oncogene family
chr10_+_99248605 0.766 NM_024954
UBTD1
ubiquitin domain containing 1
chr14_-_67353046 0.763 NM_015346
ZFYVE26
zinc finger, FYVE domain containing 26
chr3_-_158700036 0.762 NM_024621
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr4_-_149582948 0.760 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr5_-_150517499 0.759 ANXA6
annexin A6
chr12_-_54409059 0.756 CD63
CD63 molecule
chr4_-_77354011 0.755 NM_005506
SCARB2
scavenger receptor class B, member 2
chr3_+_114948550 0.753 NM_001690
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_-_172109119 0.750 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr18_+_54682261 0.750 ZNF532
zinc finger protein 532
chr13_-_109236897 0.743 NM_003749
IRS2
insulin receptor substrate 2
chr21_-_35343448 0.741 RUNX1
runt-related transcription factor 1
chr11_+_67532592 0.739 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr7_-_44071640 0.725 NM_000290
PGAM2
phosphoglycerate mutase 2 (muscle)
chr7_-_27149750 0.725 NM_019102
HOXA5
homeobox A5
chr2_+_231771622 0.719 ARMC9
armadillo repeat containing 9
chr13_-_20533703 0.715 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr13_-_20533629 0.713 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr2_+_231771584 0.713 NM_025139
ARMC9
armadillo repeat containing 9
chr2_+_219751230 0.713 FAM134A
family with sequence similarity 134, member A
chr11_+_9642229 0.711 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr6_+_151602787 0.711 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_1741680 0.707 CTSD
cathepsin D
chr21_-_35343456 0.706 NM_001754
RUNX1
runt-related transcription factor 1
chr21_-_35343500 0.705 RUNX1
runt-related transcription factor 1
chr2_-_219750975 0.704 C2orf24
chromosome 2 open reading frame 24
chr5_-_172687798 0.704 STC2
stanniocalcin 2
chr1_+_17121012 0.700 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr19_+_54149843 0.699 NM_004324
NM_138761
NM_138763
NM_138764
BAX



BCL2-associated X protein



chr3_-_188945921 0.697 BCL6
B-cell CLL/lymphoma 6
chr19_+_14405100 0.696 NM_002741
PKN1
protein kinase N1
chr5_+_133734768 0.694 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr3_+_134239860 0.693 NM_001136469
NM_023943
TMEM108

transmembrane protein 108

chrX_-_106846924 0.690 NM_004089
TSC22D3
TSC22 domain family, member 3
chr19_+_14405216 0.690 PKN1
protein kinase N1
chr9_+_116389918 0.690 ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr7_+_27102197 0.689


chr7_+_27102508 0.687


chr12_+_6703686 0.686 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr5_+_148766632 0.686 LOC728264
hypothetical LOC728264
chr6_+_151603201 0.685 AKAP12
A kinase (PRKA) anchor protein 12
chr16_-_1465021 0.685 CLCN7
chloride channel 7
chr3_-_171786468 0.684 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr19_-_9908014 0.679 NM_058164
OLFM2
olfactomedin 2
chr7_-_47588266 0.679 TNS3
tensin 3
chr13_+_48582389 0.675 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr17_-_44022595 0.674 HOXB3
homeobox B3
chr6_+_151603264 0.671


chr12_+_54396099 0.669 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 read-through transcript
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_+_238060602 0.665 NM_001042467
NM_024101
MLPH

melanophilin

chr5_+_176663385 0.665 PRELID1
PRELI domain containing 1
chr10_+_70553993 0.664 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr17_-_33043514 0.660 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr1_-_202595666 0.660 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr3_-_49370755 0.659 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr11_-_47427263 0.655 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr19_+_54708389 0.653 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_-_203557379 0.652 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr11_-_1741663 0.652 CTSD
cathepsin D
chr7_+_17304707 0.652 NM_001621
AHR
aryl hydrocarbon receptor
chrX_+_10084984 0.649 NM_001830
CLCN4
chloride channel 4
chr14_+_102458745 0.649 NM_030943
AMN
amnionless homolog (mouse)
chr16_-_57276108 0.648 NM_018231
SLC38A7
solute carrier family 38, member 7
chr11_+_101485946 0.647 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr9_-_89779180 0.645 CDK20
cyclin-dependent kinase 20
chr16_-_71549149 0.644 ZFHX3
zinc finger homeobox 3
chr8_-_54918369 0.640 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr7_+_27191534 0.639 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr5_+_72957736 0.637 NM_001080479
NM_001177693
RGNEF

190 kDa guanine nucleotide exchange factor

chr1_-_151775221 0.632 NM_014624
S100A6
S100 calcium binding protein A6
chr10_+_102746819 0.631 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr9_+_116389814 0.628 NM_004888
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr18_+_75967902 0.625 NM_014913
ADNP2
ADNP homeobox 2
chr3_-_49370682 0.618 GPX1
glutathione peroxidase 1
chr9_-_135379888 0.617 NM_001080483
TMEM8C
transmembrane protein 8C
chr2_+_238712101 0.615 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr2_+_231771623 0.612 ARMC9
armadillo repeat containing 9
chr11_+_119701047 0.608 NM_001198670
NM_001198671
NM_001198672
NM_001198673
NM_001198674
NM_001198675
NM_174926
TMEM136






transmembrane protein 136






chrX_+_101862297 0.608 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
BHLHB9





basic helix-loop-helix domain containing, class B, 9





chrX_+_100692071 0.606 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr22_+_34025872 0.605 TOM1
target of myb1 (chicken)
chr2_+_148495043 0.604 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr5_-_150517454 0.603 ANXA6
annexin A6
chr8_+_1759502 0.602 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr3_+_133619193 0.599 NM_015268
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr1_-_152797820 0.595 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr12_-_108918570 0.594 NM_001135213
NM_001135214
NM_014776
NM_057169
NM_057170
NM_139201
GIT2





G protein-coupled receptor kinase interacting ArfGAP 2





chr18_-_41801237 0.594 NM_020964
EPG5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr17_-_74487527 0.594 NM_005567
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr13_-_35818603 0.589 NM_001142296
NM_015087
SPG20

spastic paraplegia 20 (Troyer syndrome)

chr17_+_75689955 0.588 GAA
glucosidase, alpha; acid
chr17_-_44010543 0.587 NM_024015
HOXB4
homeobox B4
chr4_-_164473107 0.585 NM_000909
NPY1R
neuropeptide Y receptor Y1
chr12_-_54409067 0.585 CD63
CD63 molecule
chr1_-_94475504 0.581 ARHGAP29
Rho GTPase activating protein 29
chr12_-_108918440 0.581 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr13_-_49057707 0.581 NM_018191
RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr9_-_139128979 0.579 DPP7
dipeptidyl-peptidase 7
chr17_+_18159294 0.576 NM_144775
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr14_+_19993181 0.575 APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr16_-_1465007 0.575 CLCN7
chloride channel 7
chr14_-_91642703 0.574 NM_001127696
NM_001127697
NM_001164774
NM_001164776
NM_001164777
NM_001164778
NM_001164779
NM_001164780
NM_001164781
NM_001164782
NM_004993
NM_030660
ATXN3











ataxin 3











chr11_+_66915997 0.573 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr8_-_133140808 0.572 NM_001080399
OC90
otoconin 90
chr4_-_95482994 0.571 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chr12_-_47604930 0.570 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr1_+_181871830 0.565 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr6_-_169392771 0.564


chr1_-_153477673 0.563 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr1_+_44213229 0.562 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr15_+_46200460 0.561 NM_205850
SLC24A5
solute carrier family 24, member 5
chr19_-_5291700 0.558 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr12_+_52806103 0.555 LOC400043
hypothetical LOC400043
chr3_-_172109075 0.555 EIF5A2
eukaryotic translation initiation factor 5A2
chr3_+_185515013 0.550 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_153477511 0.546 GBA
glucosidase, beta, acid
chr3_+_160002605 0.543 MFSD1
major facilitator superfamily domain containing 1
chr1_-_152797760 0.543 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.83 9.78e-07 GO:0033036 macromolecule localization
1.94 1.02e-06 GO:0008104 protein localization
6.65 1.50e-06 GO:0007033 vacuole organization
1.99 1.44e-05 GO:0015031 protein transport
1.95 3.14e-05 GO:0045184 establishment of protein localization
8.13 6.29e-05 GO:0007040 lysosome organization
2.20 1.88e-04 GO:0034613 cellular protein localization
7.32 2.29e-04 GO:0015682 ferric iron transport
7.32 2.29e-04 GO:0033572 transferrin transport
2.19 2.30e-04 GO:0070727 cellular macromolecule localization
1.69 5.12e-04 GO:0051641 cellular localization
2.47 5.78e-04 GO:0071495 cellular response to endogenous stimulus
1.87 1.25e-03 GO:0046907 intracellular transport
4.82 1.59e-03 GO:0048704 embryonic skeletal system morphogenesis
1.71 1.59e-03 GO:0051649 establishment of localization in cell
1.36 1.67e-03 GO:0051179 localization
4.58 3.06e-03 GO:0006818 hydrogen transport
4.04 3.31e-03 GO:0048706 embryonic skeletal system development
2.37 6.08e-03 GO:0032870 cellular response to hormone stimulus
2.19 6.15e-03 GO:0006886 intracellular protein transport
1.37 6.37e-03 GO:0051234 establishment of localization
1.37 8.40e-03 GO:0006810 transport
3.19 8.56e-03 GO:0048705 skeletal system morphogenesis
4.40 1.17e-02 GO:0015992 proton transport
2.56 1.62e-02 GO:0071375 cellular response to peptide hormone stimulus
3.05 1.78e-02 GO:0008286 insulin receptor signaling pathway
2.85 1.93e-02 GO:0009952 anterior/posterior pattern formation
5.99 2.25e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
5.99 2.25e-02 GO:0015991 ATP hydrolysis coupled proton transport
1.11 3.29e-02 GO:0009987 cellular process
1.81 3.59e-02 GO:0009719 response to endogenous stimulus
2.81 3.77e-02 GO:0048562 embryonic organ morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.14 4.14e-20 GO:0005773 vacuole
4.83 9.51e-14 GO:0044437 vacuolar part
4.92 1.21e-13 GO:0005774 vacuolar membrane
3.73 3.50e-13 GO:0000323 lytic vacuole
3.73 3.50e-13 GO:0005764 lysosome
1.26 7.40e-12 GO:0043231 intracellular membrane-bounded organelle
1.26 9.44e-12 GO:0043227 membrane-bounded organelle
1.18 3.80e-11 GO:0044424 intracellular part
1.22 9.41e-11 GO:0043226 organelle
1.22 1.06e-10 GO:0043229 intracellular organelle
1.17 5.85e-10 GO:0005622 intracellular
4.51 2.56e-08 GO:0005765 lysosomal membrane
1.33 4.87e-08 GO:0044446 intracellular organelle part
1.33 4.99e-08 GO:0044422 organelle part
1.23 1.09e-07 GO:0005737 cytoplasm
1.31 1.33e-07 GO:0044444 cytoplasmic part
2.41 1.39e-06 GO:0005768 endosome
2.90 3.36e-06 GO:0010008 endosome membrane
9.98 3.98e-06 GO:0033176 proton-transporting V-type ATPase complex
2.88 4.16e-06 GO:0044440 endosomal part
3.58 1.18e-04 GO:0005770 late endosome
4.37 9.46e-04 GO:0031902 late endosome membrane
3.05 1.06e-03 GO:0005769 early endosome
1.23 1.60e-03 GO:0005634 nucleus
1.43 1.97e-03 GO:0031090 organelle membrane
5.11 2.22e-03 GO:0016469 proton-transporting two-sector ATPase complex
1.42 3.17e-03 GO:0044428 nuclear part
1.29 9.18e-03 GO:0032991 macromolecular complex
1.38 1.08e-02 GO:0043233 organelle lumen
1.38 1.08e-02 GO:0031974 membrane-enclosed lumen
1.43 1.13e-02 GO:0031981 nuclear lumen
11.09 1.17e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
1.70 1.23e-02 GO:0031410 cytoplasmic vesicle
1.38 1.37e-02 GO:0070013 intracellular organelle lumen
1.67 1.73e-02 GO:0031982 vesicle
1.51 1.74e-02 GO:0005654 nucleoplasm
1.69 2.58e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.30 2.88e-02 GO:0043234 protein complex
1.66 4.29e-02 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 8.45e-05 GO:0005515 protein binding
6.65 5.64e-04 GO:0019829 cation-transporting ATPase activity
1.11 8.49e-04 GO:0005488 binding
7.76 7.42e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
3.76 1.63e-02 GO:0042625 ATPase activity, coupled to transmembrane movement of ions