Motif ID: MYFfamily.p2

Z-value: 0.974


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.552.9e-02Click!
MYF5chr12_+_796348200.467.4e-02Click!
MYOGchr1_-_2013217110.467.6e-02Click!
MYF6chr12_+_796255380.371.6e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_34948758 4.125 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr5_-_139402989 3.247 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr11_-_129803515 3.231 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr8_-_23768242 2.869 NM_003155
STC1
stanniocalcin 1
chr11_-_129803712 2.840 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr9_-_130980302 2.517 IER5L
immediate early response 5-like
chr2_-_48836313 2.382 NM_000233
LHCGR
luteinizing hormone/choriogonadotropin receptor
chr13_-_109236897 2.306 NM_003749
IRS2
insulin receptor substrate 2
chr17_+_36493927 2.260 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr18_-_21186107 2.253 NM_015461
ZNF521
zinc finger protein 521
chr9_-_130980359 2.192 NM_203434
IER5L
immediate early response 5-like
chr20_-_23014828 2.137 NM_012072
CD93
CD93 molecule
chr18_-_21185968 2.132 ZNF521
zinc finger protein 521
chr17_-_36533903 1.961 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr17_-_36577949 1.893 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr5_-_178704934 1.883 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr6_+_99389318 1.831 POU3F2
POU class 3 homeobox 2
chr22_+_20068039 1.831 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr6_-_91063181 1.749 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr10_-_90957028 1.737 NM_003956
CH25H
cholesterol 25-hydroxylase
chr5_-_146238336 1.710 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_-_72520735 1.693 NM_173808
NEGR1
neuronal growth regulator 1
chr3_-_130807865 1.650 NM_015103
PLXND1
plexin D1
chr6_+_124166767 1.641 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr13_-_78075683 1.627 NM_006237
POU4F1
POU class 4 homeobox 1
chr16_+_29731058 1.607 PRRT2
proline-rich transmembrane protein 2
chrX_-_92815222 1.605 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr17_-_36528113 1.591 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr15_-_90999606 1.591 NM_207446
FAM174B
family with sequence similarity 174, member B
chr9_-_38414422 1.587 NM_001007563
IGFBPL1
insulin-like growth factor binding protein-like 1
chr1_-_169888373 1.575 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr10_+_89409332 1.563 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr8_+_56177567 1.560 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr3_+_85090721 1.536 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr6_-_32299757 1.532 NM_004557
NOTCH4
notch 4
chr20_-_33489383 1.510 NM_000557
GDF5
growth differentiation factor 5
chr3_-_18441763 1.492 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr16_+_85101605 1.479 NM_001451
FOXF1
forkhead box F1
chr20_+_2743613 1.470 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr16_+_85101734 1.453 FOXF1
forkhead box F1
chr15_+_94674849 1.439 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_106400322 1.374 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr1_-_32002222 1.366 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr2_+_187266899 1.328 NM_177454
FAM171B
family with sequence similarity 171, member B
chr12_+_130878870 1.309 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr10_-_30356344 1.303 KIAA1462
KIAA1462
chr19_-_13478037 1.281 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr5_+_140844810 1.263 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr9_+_4480193 1.257 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr7_-_27206249 1.226 NM_000522
HOXA13
homeobox A13
chr16_+_2461500 1.221 NM_006181
NTN3
netrin 3
chr11_+_74629597 1.205 NM_001195528
LOC441617
hypothetical LOC441617
chr10_+_120957084 1.197 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr12_+_120055013 1.197 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_-_137182125 1.190 NM_004717
DGKI
diacylglycerol kinase, iota
chr15_+_90738108 1.188 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr15_+_38437703 1.185 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr17_-_7701465 1.184 LSMD1
LSM domain containing 1
chrX_-_30237403 1.179 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr9_+_35896188 1.165 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr5_-_147142457 1.163 JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_-_36436979 1.159 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr1_+_170077234 1.154 NM_001136127
NM_015569
DNM3

dynamin 3

chr9_-_25668230 1.152 TUSC1
tumor suppressor candidate 1
chr16_-_66571863 1.144 NM_001129758
NM_022357
DPEP3

dipeptidase 3

chr13_+_34948885 1.144 NBEA
neurobeachin
chr1_+_22909916 1.141 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr1_-_72521079 1.135


chr22_-_19122047 1.133 SCARF2
scavenger receptor class F, member 2
chr22_+_28206180 1.131 NM_021076
NEFH
neurofilament, heavy polypeptide
chr9_-_139184247 1.131 NM_001013653
LRRC26
leucine rich repeat containing 26
chr2_+_114916368 1.116 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr9_-_66233945 1.108


chr10_+_42892506 1.107 NM_020630
NM_020975
RET

ret proto-oncogene

chr17_+_7846636 1.105 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr9_-_100510657 1.092 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_+_126579203 1.083 NM_182487
OLFML2A
olfactomedin-like 2A
chr9_+_27099138 1.065 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr7_+_100037817 1.060 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr3_-_62835601 1.049


chr1_+_199108705 1.048 NM_005298
GPR25
G protein-coupled receptor 25
chr3_-_144164867 1.048 NM_198504
PAQR9
progestin and adipoQ receptor family member IX
chr2_-_11727705 1.045 NM_012344
NTSR2
neurotensin receptor 2
chr10_+_52504239 1.038 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr7_+_90731671 1.030 NM_003505
FZD1
frizzled homolog 1 (Drosophila)
chr7_+_137182230 1.029


chr11_-_1576057 1.026 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr2_+_128119908 1.023 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr19_+_1226510 1.009 NM_017914
C19orf24
chromosome 19 open reading frame 24
chr12_-_53099277 1.002 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_+_70915960 1.001 NM_001012503
KRTAP5-7
keratin associated protein 5-7
chr11_+_65414677 0.996 CCDC85B
coiled-coil domain containing 85B
chr19_+_47509274 0.973 NM_173633
TMEM145
transmembrane protein 145
chr14_+_58174489 0.970 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr5_-_147142368 0.968 JAKMIP2
janus kinase and microtubule interacting protein 2
chr12_-_53099269 0.968 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_-_147142444 0.966 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr3_-_87122936 0.956 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr12_+_4788602 0.950 NM_002235
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr9_+_76302071 0.945 NM_006914
RORB
RAR-related orphan receptor B
chr4_-_13155135 0.943 NM_001189
NKX3-2
NK3 homeobox 2
chr8_-_68821131 0.942 NM_020361
CPA6
carboxypeptidase A6
chr12_+_6915698 0.941


chr5_-_147142249 0.940 JAKMIP2
janus kinase and microtubule interacting protein 2
chr19_+_56319948 0.936 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chrX_+_12066505 0.932 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr14_+_28306633 0.925 FOXG1
forkhead box G1
chr5_-_178705036 0.924 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr10_+_115793795 0.922 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr1_-_2451543 0.916 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr12_-_53099203 0.911 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_83830710 0.902 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr22_+_29333069 0.901 NM_000355
NM_001184726
TCN2

transcobalamin II

chr6_+_45498262 0.900 RUNX2
runt-related transcription factor 2
chrX_-_53367246 0.899 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr13_-_71338558 0.898 DACH1
dachshund homolog 1 (Drosophila)
chr5_+_128823904 0.890 NM_133638
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr15_+_39008822 0.890 NM_019074
DLL4
delta-like 4 (Drosophila)
chr5_+_126654354 0.863 NM_032446
MEGF10
multiple EGF-like-domains 10
chr7_-_27190882 0.862 HOXA11
homeobox A11
chr8_+_65656164 0.860 BHLHE22
basic helix-loop-helix family, member e22
chr10_-_79067476 0.850 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_+_58908152 0.849 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr1_-_102235377 0.845 NM_058170
OLFM3
olfactomedin 3
chr12_+_50342814 0.839 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr9_+_86474393 0.839 NM_001018065
NM_001018066
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr2_-_74498351 0.838 NM_001145054
C2orf81
chromosome 2 open reading frame 81
chr2_-_216944911 0.836 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr14_+_23590939 0.831 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr20_-_47618059 0.831 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr17_+_1906262 0.825 NM_001098202
HIC1
hypermethylated in cancer 1
chr11_-_106394039 0.820 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr3_-_191321601 0.815 NM_018192
LEPREL1
leprecan-like 1
chr5_+_137829065 0.812 EGR1
early growth response 1
chr2_+_100087812 0.806


chr7_+_119700924 0.804 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr1_+_22842704 0.804 NM_001114101
NM_172369
C1QC

complement component 1, q subcomponent, C chain

chr5_-_99898788 0.803


chr10_+_71833905 0.798 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr2_-_217267742 0.798 IGFBP5
insulin-like growth factor binding protein 5
chr3_-_170864111 0.797 NM_004991
MECOM
MDS1 and EVI1 complex locus
chr2_-_39040981 0.792 LOC375196
hypothetical LOC375196
chr15_+_45796802 0.788 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_-_139992621 0.779 NM_000591
CD14
CD14 molecule
chr10_-_21845721 0.778 C10orf140
chromosome 10 open reading frame 140
chr2_+_185171480 0.775 ZNF804A
zinc finger protein 804A
chr3_+_112273352 0.771 PVRL3
poliovirus receptor-related 3
chr2_-_172675480 0.771 NM_004405
DLX2
distal-less homeobox 2
chr1_+_109810743 0.770 SYPL2
synaptophysin-like 2
chr6_+_96570565 0.769 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr4_+_134292630 0.767 PCDH10
protocadherin 10
chr4_-_142273881 0.765 NM_020724
RNF150
ring finger protein 150
chr19_-_15204194 0.763 NM_024794
EPHX3
epoxide hydrolase 3
chr2_+_79593567 0.761 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr8_+_104452877 0.761 CTHRC1
collagen triple helix repeat containing 1
chr16_+_29730909 0.760 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr9_+_33667169 0.759


chr1_+_219119623 0.759 HLX
H2.0-like homeobox
chr8_+_99508425 0.757 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr17_-_74433048 0.752 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr5_+_129268352 0.749 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr1_-_38285033 0.747 NM_002699
POU3F1
POU class 3 homeobox 1
chr9_+_101623957 0.742 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chrX_+_21302317 0.740 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr10_+_63803921 0.738 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr15_+_89229275 0.736 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr16_-_87450849 0.735 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr3_-_73756668 0.735 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr15_+_89228668 0.733 NM_001143785
NM_002005
FES

feline sarcoma oncogene

chr1_-_67163001 0.730 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr14_-_59407103 0.724 NM_021136
RTN1
reticulon 1
chr19_-_52426055 0.720 NM_014417
BBC3
BCL2 binding component 3
chr16_+_66433882 0.719 THAP11
THAP domain containing 11
chr9_-_131422842 0.716 NM_199350
C9orf50
chromosome 9 open reading frame 50
chr20_-_61462960 0.708 NM_000744
CHRNA4
cholinergic receptor, nicotinic, alpha 4
chr13_+_109757593 0.704 NM_001846
COL4A2
collagen, type IV, alpha 2
chr15_+_45797977 0.704 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr2_-_219633481 0.702 NM_002181
IHH
Indian hedgehog
chr3_+_3816079 0.701 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr7_+_39956396 0.699


chr17_-_36456949 0.698 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr3_-_124650081 0.697 NM_183357
ADCY5
adenylate cyclase 5
chr11_-_132907499 0.696 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr8_+_37672427 0.695 NM_025069
ZNF703
zinc finger protein 703
chr7_+_103756339 0.694 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr12_+_101876151 0.692 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr14_-_50631407 0.684 TRIM9
tripartite motif containing 9
chrX_+_153767803 0.679 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr9_+_136673534 0.673 COL5A1
collagen, type V, alpha 1
chr14_-_50631794 0.671 TRIM9
tripartite motif containing 9
chr7_+_27190688 0.669


chr13_+_34414390 0.669 NM_015678
NBEA
neurobeachin
chr21_+_46226072 0.668 NM_001848
COL6A1
collagen, type VI, alpha 1
chr14_-_105851580 0.666 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_-_134156437 0.665 SLA
Src-like-adaptor
chr6_+_26291936 0.665 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr17_+_11085464 0.659 NM_001173461
NM_001173462
NM_207386
SHISA6


shisa homolog 6 (Xenopus laevis)


chr4_-_24641404 0.658 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr8_-_140784416 0.656 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr15_-_41698251 0.656 NM_153700
STRC
stereocilin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 1.02e-13 GO:0032502 developmental process
1.33 1.71e-13 GO:0048731 system development
1.31 2.67e-13 GO:0048856 anatomical structure development
1.22 3.03e-13 GO:0032501 multicellular organismal process
1.69 3.32e-13 GO:0007155 cell adhesion
1.69 3.32e-13 GO:0022610 biological adhesion
1.28 1.09e-12 GO:0007275 multicellular organismal development
1.46 2.43e-12 GO:0007399 nervous system development
1.39 7.01e-11 GO:0007166 cell surface receptor linked signaling pathway
1.43 2.01e-10 GO:0009653 anatomical structure morphogenesis
1.58 2.46e-10 GO:0048699 generation of neurons
1.24 3.81e-10 GO:0023052 signaling
1.54 1.70e-09 GO:0022008 neurogenesis
1.53 1.82e-09 GO:0048468 cell development
1.61 6.33e-09 GO:0030182 neuron differentiation
1.24 3.21e-08 GO:0007165 signal transduction
1.32 6.61e-08 GO:0030154 cell differentiation
1.31 7.02e-08 GO:0048869 cellular developmental process
1.67 2.42e-07 GO:0000904 cell morphogenesis involved in differentiation
1.60 1.00e-06 GO:0048666 neuron development
1.31 1.24e-06 GO:0048513 organ development
1.66 6.60e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.64 1.08e-05 GO:0048812 neuron projection morphogenesis
1.55 1.24e-05 GO:0000902 cell morphogenesis
1.60 1.25e-05 GO:0031175 neuron projection development
1.44 1.50e-05 GO:0040011 locomotion
1.52 2.31e-05 GO:0032989 cellular component morphogenesis
1.35 2.63e-05 GO:0051239 regulation of multicellular organismal process
1.63 3.87e-05 GO:0007409 axonogenesis
1.57 5.62e-05 GO:0007417 central nervous system development
1.39 1.13e-04 GO:0032879 regulation of localization
1.69 1.35e-04 GO:0007411 axon guidance
1.50 1.66e-04 GO:0009887 organ morphogenesis
1.54 2.44e-04 GO:0006935 chemotaxis
1.54 2.44e-04 GO:0042330 taxis
1.54 3.10e-04 GO:0048858 cell projection morphogenesis
1.47 3.45e-04 GO:0030030 cell projection organization
1.51 3.75e-04 GO:0007186 G-protein coupled receptor protein signaling pathway
1.52 5.39e-04 GO:0032990 cell part morphogenesis
1.66 9.82e-04 GO:0007610 behavior
1.67 1.20e-03 GO:0016337 cell-cell adhesion
1.54 1.91e-03 GO:0007268 synaptic transmission
1.98 2.37e-03 GO:0007156 homophilic cell adhesion
1.40 2.46e-03 GO:0007267 cell-cell signaling
2.05 4.50e-03 GO:0019933 cAMP-mediated signaling
1.89 4.90e-03 GO:0019935 cyclic-nucleotide-mediated signaling
1.36 5.39e-03 GO:0009888 tissue development
2.15 5.46e-03 GO:0048839 inner ear development
1.25 5.60e-03 GO:0023051 regulation of signaling
1.57 5.70e-03 GO:0007420 brain development
1.62 6.74e-03 GO:0019932 second-messenger-mediated signaling
1.48 7.64e-03 GO:0019226 transmission of nerve impulse
1.48 7.64e-03 GO:0035637 multicellular organismal signaling
1.59 9.98e-03 GO:0051046 regulation of secretion
3.10 1.04e-02 GO:0061035 regulation of cartilage development
1.34 1.17e-02 GO:0050793 regulation of developmental process
1.59 1.25e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.34 1.32e-02 GO:0006811 ion transport
1.61 1.36e-02 GO:0051270 regulation of cellular component movement
1.99 1.62e-02 GO:0043583 ear development
1.64 1.80e-02 GO:0030334 regulation of cell migration
1.30 1.92e-02 GO:0010646 regulation of cell communication
1.31 2.06e-02 GO:0009605 response to external stimulus
1.85 2.16e-02 GO:0046883 regulation of hormone secretion
1.60 2.23e-02 GO:0040012 regulation of locomotion
1.14 2.24e-02 GO:0051716 cellular response to stimulus
1.45 2.26e-02 GO:0001775 cell activation
1.81 2.41e-02 GO:0006813 potassium ion transport
1.09 2.45e-02 GO:0050794 regulation of cellular process
1.37 2.54e-02 GO:0051049 regulation of transport
2.05 2.90e-02 GO:0007605 sensory perception of sound
1.62 2.95e-02 GO:2000145 regulation of cell motility
1.41 3.10e-02 GO:0006812 cation transport
1.65 3.23e-02 GO:0030168 platelet activation
1.45 3.25e-02 GO:0030001 metal ion transport
1.48 3.36e-02 GO:0060341 regulation of cellular localization
1.63 3.72e-02 GO:0050767 regulation of neurogenesis
1.59 3.72e-02 GO:0007423 sensory organ development
1.96 3.92e-02 GO:0048736 appendage development
1.96 3.92e-02 GO:0060173 limb development
1.53 4.20e-02 GO:0044057 regulation of system process
1.84 4.70e-02 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.35 4.82e-02 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 5.06e-22 GO:0005576 extracellular region
1.41 1.83e-17 GO:0044459 plasma membrane part
1.27 3.00e-16 GO:0071944 cell periphery
1.27 3.61e-16 GO:0005886 plasma membrane
2.05 3.79e-16 GO:0031012 extracellular matrix
1.58 7.65e-15 GO:0044421 extracellular region part
1.18 7.29e-14 GO:0044425 membrane part
2.06 9.62e-14 GO:0005578 proteinaceous extracellular matrix
1.20 3.06e-13 GO:0031224 intrinsic to membrane
1.48 3.08e-12 GO:0031226 intrinsic to plasma membrane
1.46 2.70e-11 GO:0005887 integral to plasma membrane
1.14 9.08e-11 GO:0016020 membrane
1.18 3.06e-10 GO:0016021 integral to membrane
2.64 1.92e-07 GO:0045095 keratin filament
1.47 6.97e-07 GO:0005615 extracellular space
1.93 9.34e-07 GO:0034702 ion channel complex
2.24 3.73e-06 GO:0044420 extracellular matrix part
2.81 8.02e-05 GO:0031093 platelet alpha granule lumen
2.75 1.37e-04 GO:0034774 secretory granule lumen
2.42 1.55e-04 GO:0005604 basement membrane
2.64 2.27e-04 GO:0031983 vesicle lumen
1.64 3.01e-04 GO:0044456 synapse part
1.54 3.10e-04 GO:0045202 synapse
1.96 3.30e-04 GO:0034703 cation channel complex
2.64 3.77e-04 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.43 5.58e-04 GO:0030054 cell junction
1.53 1.04e-03 GO:0009986 cell surface
1.80 1.22e-03 GO:0005882 intermediate filament
1.91 1.85e-03 GO:0031225 anchored to membrane
2.79 2.90e-03 GO:0005581 collagen
2.37 3.08e-03 GO:0031091 platelet alpha granule
1.70 4.30e-03 GO:0045111 intermediate filament cytoskeleton
4.32 6.15e-03 GO:0005583 fibrillar collagen
2.00 1.43e-02 GO:0008076 voltage-gated potassium channel complex
2.00 1.43e-02 GO:0034705 potassium channel complex
2.02 3.78e-02 GO:0033267 axon part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.86 1.65e-08 GO:0022836 gated channel activity
1.69 5.84e-07 GO:0005216 ion channel activity
1.52 1.25e-06 GO:0005509 calcium ion binding
1.67 1.70e-06 GO:0022838 substrate-specific channel activity
1.63 6.53e-06 GO:0015267 channel activity
1.62 7.69e-06 GO:0022803 passive transmembrane transporter activity
1.76 1.79e-05 GO:0005261 cation channel activity
1.86 9.67e-05 GO:0005244 voltage-gated ion channel activity
1.86 9.67e-05 GO:0022832 voltage-gated channel activity
1.23 1.99e-04 GO:0004871 signal transducer activity
1.23 1.99e-04 GO:0060089 molecular transducer activity
1.34 2.72e-04 GO:0005102 receptor binding
1.93 5.86e-04 GO:0022843 voltage-gated cation channel activity
1.24 1.42e-03 GO:0004872 receptor activity
3.45 1.52e-03 GO:0005520 insulin-like growth factor binding
2.02 2.35e-03 GO:0019838 growth factor binding
1.86 2.48e-03 GO:0005539 glycosaminoglycan binding
1.52 2.68e-03 GO:0030246 carbohydrate binding
1.82 2.79e-03 GO:0001871 pattern binding
1.82 2.79e-03 GO:0030247 polysaccharide binding
1.36 4.42e-03 GO:0015075 ion transmembrane transporter activity
1.89 7.05e-03 GO:0005267 potassium channel activity
1.93 8.88e-03 GO:0008201 heparin binding
2.11 1.04e-02 GO:0042165 neurotransmitter binding
2.23 1.59e-02 GO:0005178 integrin binding
2.16 1.66e-02 GO:0030594 neurotransmitter receptor activity
2.13 2.28e-02 GO:0005230 extracellular ligand-gated ion channel activity
1.73 2.52e-02 GO:0008083 growth factor activity
2.05 2.99e-02 GO:0005201 extracellular matrix structural constituent