Motif ID: MYFfamily.p2

Z-value: 0.974


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.552.9e-02Click!
MYF5chr12_+_796348200.467.4e-02Click!
MYOGchr1_-_2013217110.467.6e-02Click!
MYF6chr12_+_796255380.371.6e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_34948758 4.125 NM_005584
 MAB21L1
mab-21-like 1 (C. elegans)
chr5_-_139402989 3.247 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
 NRG2




neuregulin 2




chr11_-_129803515 3.231 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr8_-_23768242 2.869 NM_003155
 STC1
stanniocalcin 1
chr11_-_129803712 2.840 NM_007037
 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr9_-_130980302 2.517 IER5L
immediate early response 5-like
chr2_-_48836313 2.382 NM_000233
 LHCGR
luteinizing hormone/choriogonadotropin receptor
chr13_-_109236897 2.306 NM_003749
 IRS2
insulin receptor substrate 2
chr17_+_36493927 2.260 NM_033061
 KRTAP4-7
keratin associated protein 4-7
chr18_-_21186107 2.253 NM_015461
 ZNF521
zinc finger protein 521
chr9_-_130980359 2.192 NM_203434
 IER5L
immediate early response 5-like
chr20_-_23014828 2.137 NM_012072
 CD93
CD93 molecule
chr18_-_21185968 2.132 ZNF521
zinc finger protein 521
chr17_-_36533903 1.961 NM_031854
 KRTAP4-12
keratin associated protein 4-12
chr17_-_36577949 1.893 NM_033187
 KRTAP4-3
keratin associated protein 4-3
chr5_-_178704934 1.883 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr6_+_99389318 1.831 POU3F2
POU class 3 homeobox 2
chr22_+_20068039 1.831 NM_001128635
 RIMBP3B
RIMS binding protein 3B
chr6_-_91063181 1.749 NM_021813
 BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr10_-_90957028 1.737 NM_003956
 CH25H
cholesterol 25-hydroxylase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 83 entries
enrichment   p-value GO term description
3.10 1.04e-02 GO:0061035 regulation of cartilage development
2.15 5.46e-03 GO:0048839 inner ear development
2.05 4.50e-03 GO:0019933 cAMP-mediated signaling
2.05 2.90e-02 GO:0007605 sensory perception of sound
1.99 1.62e-02 GO:0043583 ear development
1.98 2.37e-03 GO:0007156 homophilic cell adhesion
1.96 3.92e-02 GO:0048736 appendage development
1.96 3.92e-02 GO:0060173 limb development
1.89 4.90e-03 GO:0019935 cyclic-nucleotide-mediated signaling
1.85 2.16e-02 GO:0046883 regulation of hormone secretion
1.84 4.70e-02 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.81 2.41e-02 GO:0006813 potassium ion transport
1.69 3.32e-13 GO:0007155 cell adhesion
1.69 3.32e-13 GO:0022610 biological adhesion
1.69 1.35e-04 GO:0007411 axon guidance
1.67 2.42e-07 GO:0000904 cell morphogenesis involved in differentiation
1.67 1.20e-03 GO:0016337 cell-cell adhesion
1.66 6.60e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.66 9.82e-04 GO:0007610 behavior
1.65 3.23e-02 GO:0030168 platelet activation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
4.32 6.15e-03 GO:0005583 fibrillar collagen
2.81 8.02e-05 GO:0031093 platelet alpha granule lumen
2.79 2.90e-03 GO:0005581 collagen
2.75 1.37e-04 GO:0034774 secretory granule lumen
2.64 1.92e-07 GO:0045095 keratin filament
2.64 2.27e-04 GO:0031983 vesicle lumen
2.64 3.77e-04 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.42 1.55e-04 GO:0005604 basement membrane
2.37 3.08e-03 GO:0031091 platelet alpha granule
2.24 3.73e-06 GO:0044420 extracellular matrix part
2.06 9.62e-14 GO:0005578 proteinaceous extracellular matrix
2.05 3.79e-16 GO:0031012 extracellular matrix
2.02 3.78e-02 GO:0033267 axon part
2.00 1.43e-02 GO:0008076 voltage-gated potassium channel complex
2.00 1.43e-02 GO:0034705 potassium channel complex
1.96 3.30e-04 GO:0034703 cation channel complex
1.93 9.34e-07 GO:0034702 ion channel complex
1.91 1.85e-03 GO:0031225 anchored to membrane
1.80 1.22e-03 GO:0005882 intermediate filament
1.70 4.30e-03 GO:0045111 intermediate filament cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
3.45 1.52e-03 GO:0005520 insulin-like growth factor binding
2.23 1.59e-02 GO:0005178 integrin binding
2.16 1.66e-02 GO:0030594 neurotransmitter receptor activity
2.13 2.28e-02 GO:0005230 extracellular ligand-gated ion channel activity
2.11 1.04e-02 GO:0042165 neurotransmitter binding
2.05 2.99e-02 GO:0005201 extracellular matrix structural constituent
2.02 2.35e-03 GO:0019838 growth factor binding
1.93 5.86e-04 GO:0022843 voltage-gated cation channel activity
1.93 8.88e-03 GO:0008201 heparin binding
1.89 7.05e-03 GO:0005267 potassium channel activity
1.86 1.65e-08 GO:0022836 gated channel activity
1.86 9.67e-05 GO:0005244 voltage-gated ion channel activity
1.86 9.67e-05 GO:0022832 voltage-gated channel activity
1.86 2.48e-03 GO:0005539 glycosaminoglycan binding
1.82 2.79e-03 GO:0001871 pattern binding
1.82 2.79e-03 GO:0030247 polysaccharide binding
1.76 1.79e-05 GO:0005261 cation channel activity
1.73 2.52e-02 GO:0008083 growth factor activity
1.69 5.84e-07 GO:0005216 ion channel activity
1.67 1.70e-06 GO:0022838 substrate-specific channel activity