Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 1.466


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX2chr19_-_6061561,
chr19_-_6061491
0.741.2e-03Click!
RFXAPchr13_+_36291306-0.351.8e-01Click!
RFX1chr19_-_139778750.302.6e-01Click!
RFXANKchr19_+_19164732-0.273.2e-01Click!
RFX4chr12_+_1056026060.273.2e-01Click!
RFX3chr9_-_3515973-0.185.0e-01Click!
RFX5chr1_-_149586341-0.126.6e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_149649593 3.121 NM_015981
NM_171825
CAMK2A

calcium/calmodulin-dependent protein kinase II alpha

chr11_+_102485293 2.645 NM_001080463
NM_001377
DYNC2H1

dynein, cytoplasmic 2, heavy chain 1

chr22_+_29393914 2.381


chr2_+_242460553 1.935 NM_173821
C2orf85
chromosome 2 open reading frame 85
chr14_+_105012106 1.877 NM_001312
CRIP2
cysteine-rich protein 2
chr5_-_149649380 1.862 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr3_-_130630021 1.742 NM_207307
C3orf25
chromosome 3 open reading frame 25
chr15_+_68971835 1.735 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr11_+_85763425 1.732 NM_001156474
NM_021827
CCDC81

coiled-coil domain containing 81

chr4_-_156517423 1.696 MAP9
microtubule-associated protein 9
chr5_-_179712920 1.675 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr15_-_68971665 1.660 NM_020147
THAP10
THAP domain containing 10
chr2_-_187422141 1.652 NM_182521
ZSWIM2
zinc finger, SWIM-type containing 2
chr19_+_1401117 1.572 NM_005883
APC2
adenomatosis polyposis coli 2
chr5_+_157031138 1.568 NM_001145132
C5orf52
chromosome 5 open reading frame 52
chr4_-_156517544 1.561 NM_001039580
MAP9
microtubule-associated protein 9
chr5_-_157031022 1.536 SOX30
SRY (sex determining region Y)-box 30
chr22_-_43272567 1.526 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr14_+_99329198 1.518 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr11_-_65860450 1.488 NM_004292
RIN1
Ras and Rab interactor 1
chr17_-_16413188 1.457 NM_020653
ZNF287
zinc finger protein 287
chr6_-_109868400 1.436 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr14_-_59001804 1.415 NM_022571
GPR135
G protein-coupled receptor 135
chr11_+_61204392 1.410 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr16_-_65984836 1.396 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr14_-_59001603 1.393 GPR135
G protein-coupled receptor 135
chr19_-_51690989 1.383 NM_020709
PNMAL2
PNMA-like 2
chr7_-_44195405 1.380 NM_000162
GCK
glucokinase (hexokinase 4)
chr10_+_127575097 1.360 NM_145235
FANK1
fibronectin type III and ankyrin repeat domains 1
chr1_-_109458001 1.358 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr16_+_2016807 1.356 NM_001130012
NM_004785
SLC9A3R2

solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

chr6_+_135860631 1.349 NCRNA00271
non-protein coding RNA 271
chr3_-_59010777 1.313 C3orf67
chromosome 3 open reading frame 67
chr6_+_46728590 1.308 NM_004277
SLC25A27
solute carrier family 25, member 27
chr17_+_260408 1.302 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr7_-_156125876 1.286 C7orf13
chromosome 7 open reading frame 13
chr19_-_7459867 1.286 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr19_+_1401208 1.283 APC2
adenomatosis polyposis coli 2
chr8_+_120497732 1.267 NM_002514
NOV
nephroblastoma overexpressed gene
chr19_-_60382529 1.263 SYT5
synaptotagmin V
chr12_+_46863632 1.250 NM_001013635
C12orf68
chromosome 12 open reading frame 68
chr1_-_6502655 1.245 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr11_-_75056761 1.241 MAP6
microtubule-associated protein 6
chr22_-_41815277 1.240 NM_012263
TTLL1
tubulin tyrosine ligase-like family, member 1
chr9_-_134743984 1.239 NM_152572
AK8
adenylate kinase 8
chr22_-_29393786 1.238 NM_152511
DUSP18
dual specificity phosphatase 18
chr8_-_49810270 1.234 NM_001142857
NM_024593
EFCAB1

EF-hand calcium binding domain 1

chr19_-_4486202 1.214 NM_001013706
PLIN5
perilipin 5
chr6_-_35216981 1.184 NM_001093728
NM_018679
TCP11

t-complex 11 homolog (mouse)

chr2_+_128119908 1.182 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr17_-_8020332 1.182 NM_032354
NM_183065
TMEM107

transmembrane protein 107

chr4_+_87734489 1.168 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr10_-_133995323 1.162 STK32C
serine/threonine kinase 32C
chr12_+_79362256 1.156 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr16_+_3002457 1.148 NM_020982
CLDN9
claudin 9
chr3_-_42789738 1.146 NM_144719
CCDC13
coiled-coil domain containing 13
chr7_+_48041632 1.132 NM_001100159
C7orf57
chromosome 7 open reading frame 57
chr11_+_6998275 1.130 NM_176822
NLRP14
NLR family, pyrin domain containing 14
chr16_-_66007650 1.113 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr7_-_139987044 1.107 DENND2A
DENN/MADD domain containing 2A
chr14_-_88087575 1.105 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr3_-_27385856 1.090 NM_199347
NEK10
NIMA (never in mitosis gene a)- related kinase 10
chr7_+_138469029 1.080 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr1_-_48710263 1.078 SPATA6
spermatogenesis associated 6
chr11_-_75057062 1.078 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr16_-_87450849 1.064 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr6_-_152744022 1.057 SYNE1
spectrin repeat containing, nuclear envelope 1
chr6_-_121697305 1.056 NM_152730
C6orf170
chromosome 6 open reading frame 170
chr12_-_83954185 1.055 NM_001100917
TSPAN19
tetraspanin 19
chr19_-_51666503 1.045 PNMAL1
PNMA-like 1
chr17_-_58239382 1.045 NM_152598
MARCH10
membrane-associated ring finger (C3HC4) 10
chr19_-_63301418 1.044 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr1_+_22011344 1.040 NM_001013693
LDLRAD2
low density lipoprotein receptor class A domain containing 2
chr14_+_23908141 1.032 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr19_-_51666629 1.031 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr22_-_36679479 1.030 NM_032561
C22orf23
chromosome 22 open reading frame 23
chr12_+_120840829 1.024 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr19_-_63301402 1.023 ZSCAN18
zinc finger and SCAN domain containing 18
chr7_+_30777512 1.023 NM_032222
FAM188B
family with sequence similarity 188, member B
chr13_+_30404809 1.020 NM_152325
C13orf26
chromosome 13 open reading frame 26
chr12_-_112394259 1.008 NM_022363
LHX5
LIM homeobox 5
chr1_+_43410587 1.008 NM_001167965
NM_152498
NM_001167966
WDR65


WD repeat domain 65


chr14_+_105063975 0.997 NM_025268
TMEM121
transmembrane protein 121
chr19_-_63643400 0.988 NM_003433
ZNF132
zinc finger protein 132
chr4_-_171161486 0.979 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr1_+_33319287 0.977 NM_052998
ADC
arginine decarboxylase
chr17_-_71648965 0.976 NM_001454
FOXJ1
forkhead box J1
chr8_-_133756943 0.972 NM_012472
LRRC6
leucine rich repeat containing 6
chr19_-_55709577 0.961 NM_001024656
ASPDH
aspartate dehydrogenase domain containing
chr20_+_19981157 0.960 NM_015585
C20orf26
chromosome 20 open reading frame 26
chr19_-_63776442 0.950 MZF1
myeloid zinc finger 1
chr11_-_66117061 0.946 NM_018219
CCDC87
coiled-coil domain containing 87
chr8_-_94781836 0.943 LOC642924
hypothetical LOC642924
chr1_-_158182006 0.940 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr15_+_94674849 0.939 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_-_58538110 0.927 FAM107A
family with sequence similarity 107, member A
chr2_-_110319828 0.912 NPHP1
nephronophthisis 1 (juvenile)
chr1_-_48710378 0.910 NM_019073
SPATA6
spermatogenesis associated 6
chr6_-_152744143 0.907 SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_35143570 0.902 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr9_-_139101089 0.896 LOC100289341
similar to hCG2022304
chrX_+_117841761 0.892 NM_173798
ZCCHC12
zinc finger, CCHC domain containing 12
chr9_-_139128979 0.889 DPP7
dipeptidyl-peptidase 7
chr9_-_109291866 0.888 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr21_+_37661063 0.881 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr15_-_37862311 0.875 NM_152597
FSIP1
fibrous sheath interacting protein 1
chr16_+_29731058 0.871 PRRT2
proline-rich transmembrane protein 2
chr1_-_167663278 0.870 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr4_-_76774594 0.870 NM_003948
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr7_-_35192177 0.870 DPY19L2P1
dpy-19-like 2 pseudogene 1 (C. elegans)
chr10_-_128199986 0.869 NM_001004298
C10orf90
chromosome 10 open reading frame 90
chr19_-_63776547 0.868 MZF1
myeloid zinc finger 1
chr1_-_36688556 0.865 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr2_+_45022540 0.865 NM_005413
SIX3
SIX homeobox 3
chr20_-_43853945 0.862 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr19_-_63301386 0.861 ZSCAN18
zinc finger and SCAN domain containing 18
chr11_+_110890719 0.857 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr9_-_139143980 0.854


chr19_-_1441340 0.849 PCSK4
proprotein convertase subtilisin/kexin type 4
chr3_+_49002774 0.848 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr19_+_55571493 0.847 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr17_-_15185623 0.844 NM_031898
TEKT3
tektin 3
chr19_-_63565890 0.842 NM_198458
ZNF497
zinc finger protein 497
chr22_-_29393591 0.839 DUSP18
dual specificity phosphatase 18
chr1_+_153413675 0.837 TRIM46
tripartite motif containing 46
chr19_-_7896974 0.836 NM_206833
CTXN1
cortexin 1
chr9_+_111442888 0.833 NM_001037293
PALM2
paralemmin 2
chr2_-_175578156 0.827 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr13_-_43259032 0.826 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr8_+_13468722 0.825 NM_001007090
C8orf48
chromosome 8 open reading frame 48
chr10_+_25345513 0.823 NM_024838
THNSL1
threonine synthase-like 1 (S. cerevisiae)
chr14_-_73250094 0.820 NM_006029
PNMA1
paraneoplastic antigen MA1
chr3_-_59010740 0.819 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr17_+_6495694 0.819 NM_001105520
C17orf100
chromosome 17 open reading frame 100
chr9_-_109291575 0.816 KLF4
Kruppel-like factor 4 (gut)
chr8_+_144870482 0.813 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr1_-_158136521 0.812 NM_012337
CCDC19
coiled-coil domain containing 19
chr21_+_45532377 0.802 LOC642852
hypothetical LOC642852
chr10_-_17283623 0.801 TRDMT1
tRNA aspartic acid methyltransferase 1
chr4_+_40446670 0.797 NM_024677
NSUN7
NOP2/Sun domain family, member 7
chr12_-_62348506 0.790 NM_173812
DPY19L2
dpy-19-like 2 (C. elegans)
chrX_-_48578878 0.789 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_110319866 0.789 NM_000272
NM_001128178
NM_001128179
NM_207181
NPHP1



nephronophthisis 1 (juvenile)



chr5_-_133730663 0.784 NM_001113575
NM_016508
CDKL3

cyclin-dependent kinase-like 3

chr3_+_46717826 0.773 NM_147196
TMIE
transmembrane inner ear
chr10_+_125415860 0.771 NM_153442
GPR26
G protein-coupled receptor 26
chr16_-_87450734 0.770 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr7_-_13997389 0.770 NM_001163149
ETV1
ets variant 1
chr16_-_674357 0.768 NM_001005920
JMJD8
jumonji domain containing 8
chr11_-_67032675 0.766 NM_005851
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr22_+_25383392 0.765 MIAT
myocardial infarction associated transcript (non-protein coding)
chr17_-_58877276 0.765 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr19_+_2047930 0.764 IZUMO4
IZUMO family member 4
chr7_-_4889772 0.763 NM_018059
RADIL
Ras association and DIL domains
chr11_-_64641700 0.762 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr1_-_16436032 0.760 NM_030907
RSG1
REM2 and RAB-like small GTPase 1
chr17_-_40339919 0.760 GFAP
glial fibrillary acidic protein
chr10_+_133995629 0.753 NM_001143757
LRRC27
leucine rich repeat containing 27
chr7_+_2565137 0.749 NM_001100390
NM_152558
IQCE

IQ motif containing E

chr1_+_201711578 0.746 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr11_-_6998041 0.744 NM_013249
ZNF214
zinc finger protein 214
chr16_-_674318 0.741 JMJD8
jumonji domain containing 8
chr3_-_139315011 0.741 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr5_+_34875025 0.732 NM_144725
TTC23L
tetratricopeptide repeat domain 23-like
chr1_+_44230011 0.730 CCDC24
coiled-coil domain containing 24
chr19_+_40958206 0.722 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr19_-_1441403 0.716 NM_017573
PCSK4
proprotein convertase subtilisin/kexin type 4
chr1_-_153445592 0.715 THBS3
thrombospondin 3
chr15_+_37862398 0.714


chr10_-_133995315 0.714 STK32C
serine/threonine kinase 32C
chrX_-_71268475 0.714 NM_001024455
RGAG4
retrotransposon gag domain containing 4
chr11_-_10671608 0.713 NM_001100167
MRVI1
murine retrovirus integration site 1 homolog
chr17_+_76003574 0.710 FLJ35220
hypothetical protein FLJ35220
chr19_+_1397268 0.705 APC2
adenomatosis polyposis coli 2
chr1_-_50262076 0.704 AGBL4
ATP/GTP binding protein-like 4
chr22_-_37382252 0.696 LOC646851
hypothetical LOC646851
chr19_-_60369731 0.696 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr3_-_57505107 0.695 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr11_+_101423378 0.691 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr17_+_76003583 0.691 FLJ35220
hypothetical protein FLJ35220
chr2_+_173308841 0.689 RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_54565181 0.687 NM_021147
CCNO
cyclin O
chr11_-_85074848 0.686 NM_152723
CCDC89
coiled-coil domain containing 89
chr1_+_165330710 0.684 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr10_-_25344871 0.683 NM_145010
ENKUR
enkurin, TRPC channel interacting protein
chr1_+_55044323 0.676 NM_001110533
NM_152607
C1orf177

chromosome 1 open reading frame 177

chr1_+_15446354 0.672 NM_052929
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr14_+_75114692 0.669 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr9_+_129509088 0.668 NM_001012502
C9orf117
chromosome 9 open reading frame 117
chr7_+_21549357 0.666 NM_003777
DNAH11
dynein, axonemal, heavy chain 11
chr6_-_39801088 0.664 NM_145027
KIF6
kinesin family member 6
chr11_-_10671873 0.660 MRVI1
murine retrovirus integration site 1 homolog
chr11_+_85243791 0.658 NM_173556
CCDC83
coiled-coil domain containing 83
chr19_-_6344005 0.656 NM_002096
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr1_-_167603623 0.654 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr1_-_1925135 0.653 NM_001080484
KIAA1751
KIAA1751
chr11_-_10671736 0.652 MRVI1
murine retrovirus integration site 1 homolog
chr2_+_228444570 0.642 NM_178821
WDR69
WD repeat domain 69
chr1_-_26505653 0.641 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr3_-_71860958 0.638 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 1.24e-02 GO:XXXXXXX unannotated

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
8.02 4.85e-11 GO:0005930 axoneme
8.90 2.10e-09 GO:0035085 cilium axoneme
4.25 1.07e-08 GO:0005929 cilium
6.21 2.92e-07 GO:0044441 cilium part
2.59 5.82e-04 GO:0005874 microtubule
5.73 6.25e-04 GO:0019861 flagellum
13.59 3.39e-03 GO:0035086 flagellar axoneme
13.59 3.39e-03 GO:0097014 microtubule-based flagellar cytoplasm

Nothing significant found in function category.