Motif ID: PAX5.p2

Z-value: 1.295


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.467.0e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_133923992 2.568 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr3_-_133923906 2.346 NM_153240
 NPHP3
nephronophthisis 3 (adolescent)
chr19_+_61742111 1.987 NM_020828
 ZFP28
zinc finger protein 28 homolog (mouse)
chr17_-_78199384 1.297 NM_019613
 WDR45L
WDR45-like
chr14_-_52487558 1.279 NM_001134999
NM_001135000
NM_006832
 FERMT2


fermitin family member 2


chr2_+_235525355 1.248 NM_014521
 SH3BP4
SH3-domain binding protein 4
chr1_+_24944554 1.135 CLIC4
chloride intracellular channel 4
chr2_-_98713862 1.124 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_179024002 1.057 NM_003690
 PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_69212192 1.054 NM_003968
NM_198195
 UBA3

ubiquitin-like modifier activating enzyme 3

chr2_-_98714020 1.054 NM_012214
 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_52094613 1.041 NM_001012398
NM_022476
 AKTIP

AKT interacting protein

chr13_+_27094018 1.033 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr1_-_109386112 1.015 NM_001142550
NM_001142551
NM_014969
 WDR47


WD repeat domain 47


chrX_+_18353623 1.002 NM_003159
 CDKL5
cyclin-dependent kinase-like 5
chr14_-_52487386 0.981 FERMT2
fermitin family member 2
chr6_-_109911125 0.973 NM_001164313
NM_014797
 ZBTB24

zinc finger and BTB domain containing 24

chr20_-_3336586 0.961 C20orf194
chromosome 20 open reading frame 194
chr2_-_215382537 0.955 NM_000465
 BARD1
BRCA1 associated RING domain 1
chr16_-_3225360 0.922 NM_001145448
NM_198088
NM_001145446
NM_198087
 ZNF200



zinc finger protein 200




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 127 entries
enrichment   p-value GO term description
2.61 2.95e-02 GO:0048008 platelet-derived growth factor receptor signaling pathway
1.89 3.41e-02 GO:0046519 sphingoid metabolic process
1.73 9.72e-06 GO:0016311 dephosphorylation
1.72 8.05e-05 GO:0006470 protein dephosphorylation
1.61 2.51e-04 GO:0051493 regulation of cytoskeleton organization
1.61 3.22e-03 GO:0051099 positive regulation of binding
1.59 3.32e-02 GO:0043388 positive regulation of DNA binding
1.56 1.12e-03 GO:0051169 nuclear transport
1.56 1.25e-03 GO:0006913 nucleocytoplasmic transport
1.51 8.26e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.46 1.62e-05 GO:0018193 peptidyl-amino acid modification
1.43 8.28e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.42 4.35e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.41 1.66e-03 GO:0044257 cellular protein catabolic process
1.40 2.91e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.40 2.33e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.40 3.28e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.40 3.68e-03 GO:0019941 modification-dependent protein catabolic process
1.40 1.77e-02 GO:0032446 protein modification by small protein conjugation
1.39 7.00e-06 GO:0044265 cellular macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
1.73 3.29e-04 GO:0005925 focal adhesion
1.72 1.32e-04 GO:0030055 cell-substrate junction
1.70 1.64e-06 GO:0005912 adherens junction
1.70 4.37e-04 GO:0005924 cell-substrate adherens junction
1.67 3.86e-07 GO:0031252 cell leading edge
1.65 5.08e-06 GO:0070161 anchoring junction
1.65 2.15e-02 GO:0030027 lamellipodium
1.64 3.61e-02 GO:0046930 pore complex
1.61 3.86e-02 GO:0016585 chromatin remodeling complex
1.46 3.64e-04 GO:0005635 nuclear envelope
1.44 2.24e-03 GO:0005813 centrosome
1.41 4.51e-05 GO:0048471 perinuclear region of cytoplasm
1.39 1.66e-02 GO:0016323 basolateral plasma membrane
1.37 1.41e-03 GO:0005815 microtubule organizing center
1.31 1.13e-20 GO:0005829 cytosol
1.29 2.51e-05 GO:0044451 nucleoplasm part
1.29 8.49e-05 GO:0015630 microtubule cytoskeleton
1.29 7.53e-03 GO:0000139 Golgi membrane
1.26 2.70e-08 GO:0005654 nucleoplasm
1.26 5.55e-03 GO:0044431 Golgi apparatus part

Gene overrepresentation in function category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
1.75 3.84e-04 GO:0004725 protein tyrosine phosphatase activity
1.69 1.93e-06 GO:0004721 phosphoprotein phosphatase activity
1.56 7.97e-04 GO:0000287 magnesium ion binding
1.55 2.74e-02 GO:0035091 phosphatidylinositol binding
1.54 2.21e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.49 2.69e-05 GO:0032403 protein complex binding
1.48 1.75e-04 GO:0016791 phosphatase activity
1.46 3.36e-08 GO:0019904 protein domain specific binding
1.44 2.62e-07 GO:0004674 protein serine/threonine kinase activity
1.43 2.65e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.43 2.98e-04 GO:0008134 transcription factor binding
1.43 1.03e-03 GO:0016881 acid-amino acid ligase activity
1.41 1.21e-02 GO:0019787 small conjugating protein ligase activity
1.39 6.89e-06 GO:0030695 GTPase regulator activity
1.38 2.27e-04 GO:0000988 protein binding transcription factor activity
1.38 2.27e-04 GO:0000989 transcription factor binding transcription factor activity
1.38 3.18e-04 GO:0003712 transcription cofactor activity
1.38 9.76e-04 GO:0042578 phosphoric ester hydrolase activity
1.38 7.36e-03 GO:0005083 small GTPase regulator activity
1.38 4.43e-02 GO:0019900 kinase binding