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• Activity deltas table
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Motif ID: PAX5.p2

Z-value: 1.295

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_133923992	2.568		NPHP3-ACAD11	NPHP3-ACAD11 read-through transcript
chr3_-_133923906	2.346	NM_153240	NPHP3	nephronophthisis 3 (adolescent)
chr19_+_61742111	1.987	NM_020828	ZFP28	zinc finger protein 28 homolog (mouse)
chr17_-_78199384	1.297	NM_019613	WDR45L	WDR45-like
chr14_-_52487558	1.279	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr2_+_235525355	1.248	NM_014521	SH3BP4	SH3-domain binding protein 4
chr1_+_24944554	1.135		CLIC4	chloride intracellular channel 4
chr2_-_98713862	1.124		MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_179024002	1.057	NM_003690	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_69212192	1.054	NM_003968 NM_198195	UBA3	ubiquitin-like modifier activating enzyme 3
chr2_-_98714020	1.054	NM_012214	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_52094613	1.041	NM_001012398 NM_022476	AKTIP	AKT interacting protein
chr13_+_27094018	1.033		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr1_-_109386112	1.015	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chrX_+_18353623	1.002	NM_003159	CDKL5	cyclin-dependent kinase-like 5
chr14_-_52487386	0.981		FERMT2	fermitin family member 2
chr6_-_109911125	0.973	NM_001164313 NM_014797	ZBTB24	zinc finger and BTB domain containing 24
chr20_-_3336586	0.961		C20orf194	chromosome 20 open reading frame 194
chr2_-_215382537	0.955	NM_000465	BARD1	BRCA1 associated RING domain 1
chr16_-_3225360	0.922	NM_001145448 NM_198088 NM_001145446 NM_198087	ZNF200	zinc finger protein 200
chr1_+_24944493	0.908		CLIC4	chloride intracellular channel 4
chr2_+_56264627	0.898	NM_001080433	CCDC85A	coiled-coil domain containing 85A
chr18_+_11971443	0.892	NM_014214	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr1_+_113734997	0.870	NM_001142782 NM_152900	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr18_+_11971421	0.867		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr6_-_109911015	0.852		ZBTB24	zinc finger and BTB domain containing 24
chr6_+_132170847	0.841	NM_006208	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr3_-_127677451	0.838	NM_001040653 NM_025112	ZXDC	ZXD family zinc finger C
chr8_+_25098296	0.831		DOCK5	dedicator of cytokinesis 5
chr12_-_13044448	0.830		HEBP1	heme binding protein 1
chr12_-_13044314	0.829		HEBP1	heme binding protein 1
chr8_+_25098171	0.828	NM_024940	DOCK5	dedicator of cytokinesis 5
chr9_-_36391149	0.825	NM_194330	RNF38	ring finger protein 38
chr20_-_51644187	0.818		ZNF217	zinc finger protein 217
chr12_-_13044467	0.815	NM_015987	HEBP1	heme binding protein 1
chr11_+_101485946	0.808	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr6_-_99502528	0.796	NM_012160	FBXL4	F-box and leucine-rich repeat protein 4
chr10_-_12124778	0.795	NM_015542	UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_-_108860740	0.791	NM_005443	PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr2_+_233270286	0.789		GIGYF2	GRB10 interacting GYF protein 2
chr10_+_171410	0.781		ZMYND11	zinc finger, MYND-type containing 11
chr17_+_26060617	0.778
chr9_-_33157300	0.769		B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr1_-_115433570	0.766	NM_005725	TSPAN2	tetraspanin 2
chr1_-_93919789	0.764	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr2_-_11402150	0.762	NM_004850	ROCK2	Rho-associated, coiled-coil containing protein kinase 2
chr10_-_35143900	0.754	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr14_+_103251798	0.754	NM_001198953 NM_024071	ZFYVE21	zinc finger, FYVE domain containing 21
chr3_-_198509276	0.749		DLG1	discs, large homolog 1 (Drosophila)
chr13_+_26029879	0.749		WASF3	WAS protein family, member 3
chr1_+_181259317	0.746
chr12_-_74711642	0.735	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr3_-_151171190	0.735	NM_002628 NM_053024	PFN2	profilin 2
chr8_-_99906944	0.732	NM_006281	STK3	serine/threonine kinase 3
chr16_+_67131161	0.732	NM_133458	ZFP90	zinc finger protein 90 homolog (mouse)
chr8_-_67687980	0.729	NM_001080416 NM_001144755	MYBL1 LOC645895	v-myb myeloblastosis viral oncogene homolog (avian)-like 1 hypothetical LOC645895
chr2_+_238265519	0.728	NM_001137551 NM_001137552 NM_001137553 NM_004735	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr21_+_45318861	0.717	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr2_+_24126140	0.713		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr16_+_67130616	0.691		ZFP90	zinc finger protein 90 homolog (mouse)
chr1_+_24944346	0.688	NM_013943	CLIC4	chloride intracellular channel 4
chr13_+_43351968	0.688	NM_153218	C13orf31	chromosome 13 open reading frame 31
chr17_+_75849221	0.683	NM_020914 NM_020954	RNF213	ring finger protein 213
chr1_-_233879617	0.682	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr1_+_86943103	0.673		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr7_-_28186671	0.670		JAZF1	JAZF zinc finger 1
chr10_-_15250616	0.661	NM_004808	NMT2	N-myristoyltransferase 2
chr18_+_54489763	0.647		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr11_+_109468734	0.645		ZC3H12C	zinc finger CCCH-type containing 12C
chr1_+_86943074	0.645		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr13_-_113066366	0.644	NM_024719	GRTP1	growth hormone regulated TBC protein 1
chr10_-_62431203	0.639		RHOBTB1	Rho-related BTB domain containing 1
chr18_+_11971552	0.636		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr14_-_50367513	0.634	NM_016350 NM_020921 NM_182944 NM_182946	NIN	ninein (GSK3B interacting protein)
chr5_+_135392482	0.634	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr9_+_96807107	0.634		C9orf3	chromosome 9 open reading frame 3
chr13_+_97426713	0.632		IPO5	importin 5
chr3_+_32255158	0.627	NM_178868	CMTM8	CKLF-like MARVEL transmembrane domain containing 8
chr4_-_158111995	0.626	NM_016205	PDGFC	platelet derived growth factor C
chr3_-_187025501	0.625	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr8_-_13035102	0.624	NM_006094	DLC1	deleted in liver cancer 1
chr10_-_135036805	0.620	NM_004092	ECHS1	enoyl CoA hydratase, short chain, 1, mitochondrial
chr13_-_43351825	0.620	NM_144974	CCDC122	coiled-coil domain containing 122
chr16_-_56789142	0.617	NM_001896	CSNK2A2	casein kinase 2, alpha prime polypeptide
chr18_+_53862744	0.608		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_177837540	0.603		NFE2L2	nuclear factor (erythroid-derived 2)-like 2
chr18_+_9126742	0.593	NM_001083625 NM_015208	ANKRD12	ankyrin repeat domain 12
chr2_-_99472843	0.592		REV1	REV1 homolog (S. cerevisiae)
chr5_+_122138677	0.592		SNX2	sorting nexin 2
chr10_+_124124083	0.589	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_-_23683214	0.587		ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr21_+_46473494	0.585		MCM3AP-AS1	MCM3AP antisense RNA 1 (non-protein coding)
chr20_-_23566325	0.579	NM_000099	CST3	cystatin C
chr5_-_114660139	0.579	NM_001040440	CCDC112	coiled-coil domain containing 112
chr1_-_23683308	0.578	NM_001143778 NM_017707	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr2_-_158440587	0.577	NM_001111067	ACVR1	activin A receptor, type I
chr7_-_105712565	0.576		NAMPT	nicotinamide phosphoribosyltransferase
chr2_+_219354948	0.575		CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chr2_+_112529270	0.573	NM_032824	TMEM87B	transmembrane protein 87B
chr6_-_114398946	0.573		HDAC2	histone deacetylase 2
chr15_-_27901828	0.569	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr17_-_15407497	0.568	NM_001135036 NM_145301	FAM18B2-CDRT4 FAM18B2	FAM18B2-CDRT4 read-through transcript family with sequence similarity 18, member B2
chr5_+_122138661	0.568		SNX2	sorting nexin 2
chr13_-_27092677	0.568	NM_153371	LNX2	ligand of numb-protein X 2
chr5_+_122138636	0.566	NM_003100	SNX2	sorting nexin 2
chr14_+_55116549	0.565	NM_001079521 NM_001079522 NM_004986 NM_182926	KTN1	kinectin 1 (kinesin receptor)
chrX_+_17665483	0.562	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr7_+_115926855	0.562		CAV2	caveolin 2
chrX_-_132947141	0.561		GPC3	glypican 3
chr13_-_113066202	0.560		GRTP1	growth hormone regulated TBC protein 1
chr18_+_12937972	0.560	NM_001013437 NM_031216	SEH1L	SEH1-like (S. cerevisiae)
chr13_+_27094024	0.557	NM_015972	POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr9_+_494661	0.555	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr6_+_17389752	0.549	NM_001143942	RBM24	RNA binding motif protein 24
chr4_+_3264509	0.548		RGS12	regulator of G-protein signaling 12
chr1_+_86942874	0.547		SH3GLB1	SH3-domain GRB2-like endophilin B1
chr2_-_179023600	0.547	NM_001139518 NM_001139517	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr6_+_132170888	0.546		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr20_-_39680405	0.546	NM_032221	CHD6	chromodomain helicase DNA binding protein 6
chr3_-_187025438	0.543		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr15_+_54998144	0.542		TCF12	transcription factor 12
chr6_-_99502495	0.538		FBXL4	F-box and leucine-rich repeat protein 4
chr17_-_74432800	0.535		TIMP2	TIMP metallopeptidase inhibitor 2
chr7_-_107883929	0.535	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr1_+_9275542	0.534		SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr3_-_151171576	0.533		PFN2	profilin 2
chr13_+_26029799	0.533	NM_006646	WASF3	WAS protein family, member 3
chr18_+_27925923	0.533		RNF138	ring finger protein 138
chr2_-_114230455	0.530		SLC35F5	solute carrier family 35, member F5
chr8_-_71478041	0.530		NCOA2	nuclear receptor coactivator 2
chr6_-_13819463	0.529		RANBP9	RAN binding protein 9
chr6_-_101435727	0.529		ASCC3	activating signal cointegrator 1 complex subunit 3
chr18_+_12938010	0.527		SEH1L	SEH1-like (S. cerevisiae)
chr2_-_97572580	0.526
chr12_-_93568336	0.523	NM_020698	TMCC3	transmembrane and coiled-coil domain family 3
chr14_+_102128844	0.523	NM_015156	RCOR1	REST corepressor 1
chr15_-_53667800	0.521		PYGO1	pygopus homolog 1 (Drosophila)
chr4_-_170428564	0.520		SH3RF1	SH3 domain containing ring finger 1
chr3_-_123716471	0.518	NM_002264	KPNA1	karyopherin alpha 1 (importin alpha 5)
chr2_+_10101081	0.518	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr2_-_16710551	0.514	NM_030797	FAM49A	family with sequence similarity 49, member A
chr8_+_38208165	0.514	NM_001164234 NM_015214	DDHD2	DDHD domain containing 2
chr6_+_160068553	0.513		WTAP	Wilms tumor 1 associated protein
chr17_-_72218535	0.511	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr20_-_55718351	0.511	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr5_-_171814026	0.510	NM_001017995	SH3PXD2B	SH3 and PX domains 2B
chr4_-_102487649	0.509	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr13_+_110565587	0.509	NM_001113511 NM_001113512 NM_145735	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr18_+_54489798	0.509		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_95188989	0.509	NM_032788	ZNF514	zinc finger protein 514
chr3_-_127677400	0.508		ZXDC	ZXD family zinc finger C
chr4_-_37364327	0.507	NM_001085399 NM_001085400	RELL1	RELT-like 1
chr1_+_9275518	0.506	NM_025106	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr15_-_50375143	0.503	NM_018728	MYO5C	myosin VC
chr6_-_119297851	0.502		MCM9	minichromosome maintenance complex component 9
chr17_-_60088773	0.500	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr18_-_43711143	0.498		SMAD2	SMAD family member 2
chr2_+_61146542	0.497		KIAA1841	KIAA1841
chr8_-_102287083	0.497	NM_001042510 NM_016096	ZNF706	zinc finger protein 706
chr16_-_79687367	0.494	NM_004483	GCSH	glycine cleavage system protein H (aminomethyl carrier)
chr12_-_74711474	0.489		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr14_-_52232316	0.486		ERO1L	ERO1-like (S. cerevisiae)
chr4_-_177950658	0.485	NM_005429	VEGFC	vascular endothelial growth factor C
chr3_+_171558188	0.484		SKIL	SKI-like oncogene
chr14_-_38971370	0.481	NM_203301	FBXO33	F-box protein 33
chr5_+_79986254	0.479		MSH3	mutS homolog 3 (E. coli)
chr11_-_86343859	0.479	NM_012193	FZD4	frizzled homolog 4 (Drosophila)
chr2_-_25328452	0.478	NM_153759	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr2_+_238265617	0.477		LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr14_+_56927014	0.477	NM_001011713	NAA30	N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_142664490	0.476	NM_001032394 NM_001032395 NM_020455 NM_198569	GPR126	G protein-coupled receptor 126
chr4_+_99401543	0.476	NM_001100426 NM_001100427 NM_001100428 NM_001100429 NM_001100430 NM_021159	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1
chr3_+_23961739	0.476	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr12_-_103055924	0.476	NM_006166	NFYB	nuclear transcription factor Y, beta
chr12_+_102982365	0.476	NM_013320	HCFC2	host cell factor C2
chr20_+_60130963	0.474		LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr14_+_99329198	0.474	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr18_+_53862386	0.472	NM_001144967 NM_015277	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr7_+_77004267	0.471		PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr11_-_72170533	0.470		STARD10	StAR-related lipid transfer (START) domain containing 10
chr6_+_160068531	0.470		WTAP	Wilms tumor 1 associated protein
chr12_+_3056781	0.469	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr6_+_117910472	0.469	NM_173674	DCBLD1	discoidin, CUB and LCCL domain containing 1
chr2_-_97978421	0.466	NM_015348	TMEM131	transmembrane protein 131
chr3_+_171558215	0.466		SKIL	SKI-like oncogene
chr13_+_95002942	0.465	NM_006984	CLDN10	claudin 10
chr4_-_53220073	0.463	NM_022832	USP46	ubiquitin specific peptidase 46
chr1_-_93199586	0.462	NM_001006605	FAM69A	family with sequence similarity 69, member A
chr15_-_20637731	0.462	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_131021169	0.462	NM_016623	FAM49B	family with sequence similarity 49, member B
chr8_-_131021078	0.461		FAM49B	family with sequence similarity 49, member B
chr10_+_124124196	0.461		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_+_160068598	0.459	NM_152857	WTAP	Wilms tumor 1 associated protein
chr18_+_54489658	0.459		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_+_70459686	0.458		SRSF11	serine/arginine-rich splicing factor 11
chr12_+_2938703	0.457	NM_003213 NM_201441 NM_201443	TEAD4	TEA domain family member 4
chr7_+_55054152	0.456	NM_005228 NM_201282 NM_201283 NM_201284	EGFR	epidermal growth factor receptor
chr10_+_121475628	0.455		INPP5F	inositol polyphosphate-5-phosphatase F
chr18_-_63334902	0.454	NM_032160	DSEL	dermatan sulfate epimerase-like
chr12_+_67290881	0.454	NM_001010942 NM_015646	RAP1B	RAP1B, member of RAS oncogene family

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	2.32e-31	GO:0044237	cellular metabolic process
1.23	3.86e-28	GO:0044260	cellular macromolecule metabolic process
1.17	5.63e-25	GO:0044238	primary metabolic process
1.15	3.05e-24	GO:0008152	metabolic process
1.09	8.34e-24	GO:0009987	cellular process
1.19	6.96e-22	GO:0043170	macromolecule metabolic process
1.34	1.22e-20	GO:0006464	protein modification process
1.32	1.30e-19	GO:0043412	macromolecule modification
1.27	7.08e-19	GO:0044267	cellular protein metabolic process
1.12	2.24e-13	GO:0050794	regulation of cellular process
1.21	2.95e-13	GO:0019538	protein metabolic process
1.11	8.56e-13	GO:0050789	regulation of biological process
1.10	1.61e-12	GO:0065007	biological regulation
1.30	4.34e-11	GO:0009966	regulation of signal transduction
1.24	4.64e-11	GO:0048523	negative regulation of cellular process
1.34	3.98e-10	GO:0006793	phosphorus metabolic process
1.34	3.98e-10	GO:0006796	phosphate metabolic process
1.20	6.58e-10	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17	1.01e-09	GO:0016043	cellular component organization
1.31	1.22e-09	GO:0044248	cellular catabolic process
1.18	2.40e-09	GO:0034641	cellular nitrogen compound metabolic process
1.16	3.43e-09	GO:0071840	cellular component organization or biogenesis
1.17	5.63e-09	GO:0006807	nitrogen compound metabolic process
1.25	8.51e-09	GO:0023051	regulation of signaling
1.26	1.75e-08	GO:0009056	catabolic process
1.40	2.91e-08	GO:0007167	enzyme linked receptor protein signaling pathway
1.14	4.50e-08	GO:0019222	regulation of metabolic process
1.20	5.02e-08	GO:0048519	negative regulation of biological process
1.24	1.02e-07	GO:0006996	organelle organization
1.34	3.38e-07	GO:0046907	intracellular transport
1.30	3.64e-07	GO:0007049	cell cycle
1.18	3.82e-07	GO:0071842	cellular component organization at cellular level
1.26	4.11e-07	GO:0051641	cellular localization
1.15	4.30e-07	GO:0060255	regulation of macromolecule metabolic process
1.42	4.35e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	5.27e-07	GO:0031323	regulation of cellular metabolic process
1.17	8.17e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.19	8.31e-07	GO:0090304	nucleic acid metabolic process
1.14	2.10e-06	GO:0080090	regulation of primary metabolic process
1.25	2.86e-06	GO:0033036	macromolecule localization
1.27	4.47e-06	GO:0051246	regulation of protein metabolic process
1.36	5.91e-06	GO:0009057	macromolecule catabolic process
1.39	7.00e-06	GO:0044265	cellular macromolecule catabolic process
1.12	8.42e-06	GO:0051716	cellular response to stimulus
1.73	9.72e-06	GO:0016311	dephosphorylation
1.32	1.02e-05	GO:0006468	protein phosphorylation
1.27	1.50e-05	GO:0032268	regulation of cellular protein metabolic process
1.46	1.62e-05	GO:0018193	peptidyl-amino acid modification
1.17	1.85e-05	GO:0048522	positive regulation of cellular process
1.26	2.26e-05	GO:0008104	protein localization
1.26	3.06e-05	GO:0043067	regulation of programmed cell death
1.26	4.03e-05	GO:0010941	regulation of cell death
1.26	6.72e-05	GO:0042981	regulation of apoptosis
1.16	6.93e-05	GO:0044249	cellular biosynthetic process
1.24	8.00e-05	GO:0051649	establishment of localization in cell
1.72	8.05e-05	GO:0006470	protein dephosphorylation
1.29	9.35e-05	GO:0051128	regulation of cellular component organization
1.15	1.10e-04	GO:0048518	positive regulation of biological process
1.15	1.20e-04	GO:0009058	biosynthetic process
1.21	1.33e-04	GO:0065009	regulation of molecular function
1.29	1.55e-04	GO:0031399	regulation of protein modification process
1.28	2.19e-04	GO:0016310	phosphorylation
1.61	2.51e-04	GO:0051493	regulation of cytoskeleton organization
1.27	2.67e-04	GO:0033554	cellular response to stress
1.27	2.80e-04	GO:0045184	establishment of protein localization
1.29	3.38e-04	GO:0016192	vesicle-mediated transport
1.26	4.21e-04	GO:0016265	death
1.26	5.11e-04	GO:0008219	cell death
1.12	5.73e-04	GO:0007165	signal transduction
1.18	6.03e-04	GO:0034645	cellular macromolecule biosynthetic process
1.17	6.83e-04	GO:0048583	regulation of response to stimulus
1.26	8.26e-04	GO:0015031	protein transport
1.51	8.26e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.43	8.28e-04	GO:0006511	ubiquitin-dependent protein catabolic process
1.18	9.67e-04	GO:0009059	macromolecule biosynthetic process
1.56	1.12e-03	GO:0051169	nuclear transport
1.28	1.13e-03	GO:0012501	programmed cell death
1.56	1.25e-03	GO:0006913	nucleocytoplasmic transport
1.30	1.32e-03	GO:0051726	regulation of cell cycle
1.11	1.32e-03	GO:0023052	signaling
1.41	1.66e-03	GO:0044257	cellular protein catabolic process
1.33	1.80e-03	GO:0034613	cellular protein localization
1.32	1.96e-03	GO:0070727	cellular macromolecule localization
1.28	2.13e-03	GO:0019220	regulation of phosphate metabolic process
1.28	2.13e-03	GO:0051174	regulation of phosphorus metabolic process
1.40	2.33e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
1.20	2.41e-03	GO:0035556	intracellular signal transduction
1.17	3.16e-03	GO:0016070	RNA metabolic process
1.61	3.22e-03	GO:0051099	positive regulation of binding
1.40	3.28e-03	GO:0043632	modification-dependent macromolecule catabolic process
1.40	3.68e-03	GO:0019941	modification-dependent protein catabolic process
1.27	4.24e-03	GO:0006915	apoptosis
1.25	4.32e-03	GO:0022402	cell cycle process
1.38	4.79e-03	GO:0030163	protein catabolic process
1.32	4.95e-03	GO:0051338	regulation of transferase activity
1.28	6.26e-03	GO:0001932	regulation of protein phosphorylation
1.39	7.45e-03	GO:0033043	regulation of organelle organization
1.34	8.80e-03	GO:0043066	negative regulation of apoptosis
1.33	1.01e-02	GO:0060548	negative regulation of cell death
1.31	1.14e-02	GO:0043549	regulation of kinase activity
1.33	1.17e-02	GO:0043069	negative regulation of programmed cell death
1.28	1.40e-02	GO:0000278	mitotic cell cycle
1.26	1.76e-02	GO:0042325	regulation of phosphorylation
1.40	1.77e-02	GO:0032446	protein modification by small protein conjugation
1.34	1.80e-02	GO:0006886	intracellular protein transport
1.37	1.82e-02	GO:0070647	protein modification by small protein conjugation or removal
1.31	1.83e-02	GO:0045859	regulation of protein kinase activity
1.29	2.01e-02	GO:0010942	positive regulation of cell death
1.37	2.29e-02	GO:0051098	regulation of binding
1.25	2.31e-02	GO:0022403	cell cycle phase
1.12	2.42e-02	GO:0010468	regulation of gene expression
1.20	2.51e-02	GO:0010646	regulation of cell communication
1.22	2.58e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.35	2.72e-02	GO:0051301	cell division
1.20	2.73e-02	GO:0022607	cellular component assembly
2.61	2.95e-02	GO:0048008	platelet-derived growth factor receptor signaling pathway
1.29	3.01e-02	GO:0043068	positive regulation of programmed cell death
1.19	3.27e-02	GO:0050790	regulation of catalytic activity
1.59	3.32e-02	GO:0043388	positive regulation of DNA binding
1.89	3.41e-02	GO:0046519	sphingoid metabolic process
1.21	3.52e-02	GO:0009892	negative regulation of metabolic process
1.12	3.61e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.12	3.66e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	3.96e-02	GO:0016568	chromatin modification
1.34	4.03e-02	GO:0044419	interspecies interaction between organisms
1.18	4.19e-02	GO:0044085	cellular component biogenesis
1.10	4.55e-02	GO:0051179	localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	6.53e-55	GO:0005622	intracellular
1.13	3.04e-54	GO:0044424	intracellular part
1.17	1.29e-42	GO:0005737	cytoplasm
1.16	6.49e-42	GO:0043227	membrane-bounded organelle
1.15	1.59e-41	GO:0043231	intracellular membrane-bounded organelle
1.14	1.08e-40	GO:0043226	organelle
1.14	1.47e-40	GO:0043229	intracellular organelle
1.20	5.78e-34	GO:0044444	cytoplasmic part
1.19	5.24e-27	GO:0005634	nucleus
1.31	1.13e-20	GO:0005829	cytosol
1.15	2.99e-16	GO:0044422	organelle part
1.14	1.24e-15	GO:0044446	intracellular organelle part
1.24	1.39e-12	GO:0044428	nuclear part
1.03	1.31e-11	GO:0044464	cell part
1.03	1.48e-11	GO:0005623	cell
1.21	3.86e-10	GO:0070013	intracellular organelle lumen
1.20	8.71e-10	GO:0031974	membrane-enclosed lumen
1.20	1.80e-09	GO:0043233	organelle lumen
1.22	1.12e-08	GO:0031981	nuclear lumen
1.26	2.70e-08	GO:0005654	nucleoplasm
1.67	3.86e-07	GO:0031252	cell leading edge
1.21	7.41e-07	GO:0012505	endomembrane system
1.70	1.64e-06	GO:0005912	adherens junction
1.65	5.08e-06	GO:0070161	anchoring junction
1.25	1.36e-05	GO:0005794	Golgi apparatus
1.29	2.51e-05	GO:0044451	nucleoplasm part
1.41	4.51e-05	GO:0048471	perinuclear region of cytoplasm
1.16	4.67e-05	GO:0031090	organelle membrane
1.29	8.49e-05	GO:0015630	microtubule cytoskeleton
1.72	1.32e-04	GO:0030055	cell-substrate junction
1.73	3.29e-04	GO:0005925	focal adhesion
1.46	3.64e-04	GO:0005635	nuclear envelope
1.70	4.37e-04	GO:0005924	cell-substrate adherens junction
1.12	1.11e-03	GO:0043234	protein complex
1.37	1.41e-03	GO:0005815	microtubule organizing center
1.44	2.24e-03	GO:0005813	centrosome
1.12	3.93e-03	GO:0043228	non-membrane-bounded organelle
1.12	3.93e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.16	4.46e-03	GO:0005856	cytoskeleton
1.26	5.55e-03	GO:0044431	Golgi apparatus part
1.29	7.53e-03	GO:0000139	Golgi membrane
1.23	8.13e-03	GO:0031967	organelle envelope
1.17	8.15e-03	GO:0005739	mitochondrion
1.23	9.71e-03	GO:0031975	envelope
1.25	1.03e-02	GO:0030054	cell junction
1.39	1.66e-02	GO:0016323	basolateral plasma membrane
1.65	2.15e-02	GO:0030027	lamellipodium
1.64	3.61e-02	GO:0046930	pore complex
1.61	3.86e-02	GO:0016585	chromatin remodeling complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	7.09e-31	GO:0005515	protein binding
1.08	1.69e-25	GO:0005488	binding
1.12	4.67e-10	GO:0003824	catalytic activity
1.21	5.66e-10	GO:0000166	nucleotide binding
1.32	2.97e-08	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.46	3.36e-08	GO:0019904	protein domain specific binding
1.34	4.71e-08	GO:0016301	kinase activity
1.21	9.91e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.21	1.14e-07	GO:0017076	purine nucleotide binding
1.21	1.26e-07	GO:0032553	ribonucleotide binding
1.21	1.26e-07	GO:0032555	purine ribonucleotide binding
1.34	1.76e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.44	2.62e-07	GO:0004674	protein serine/threonine kinase activity
1.22	3.88e-07	GO:0030554	adenyl nucleotide binding
1.22	5.59e-07	GO:0032559	adenyl ribonucleotide binding
1.22	7.46e-07	GO:0005524	ATP binding
1.36	1.31e-06	GO:0004672	protein kinase activity
1.69	1.93e-06	GO:0004721	phosphoprotein phosphatase activity
1.20	6.68e-06	GO:0016740	transferase activity
1.39	6.89e-06	GO:0030695	GTPase regulator activity
1.37	1.91e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.49	2.69e-05	GO:0032403	protein complex binding
1.29	4.76e-05	GO:0019899	enzyme binding
1.48	1.75e-04	GO:0016791	phosphatase activity
1.38	2.27e-04	GO:0000988	protein binding transcription factor activity
1.38	2.27e-04	GO:0000989	transcription factor binding transcription factor activity
1.43	2.65e-04	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.43	2.98e-04	GO:0008134	transcription factor binding
1.38	3.18e-04	GO:0003712	transcription cofactor activity
1.75	3.84e-04	GO:0004725	protein tyrosine phosphatase activity
1.26	5.69e-04	GO:0042802	identical protein binding
1.56	7.97e-04	GO:0000287	magnesium ion binding
1.38	9.76e-04	GO:0042578	phosphoric ester hydrolase activity
1.43	1.03e-03	GO:0016881	acid-amino acid ligase activity
1.22	1.64e-03	GO:0030234	enzyme regulator activity
1.54	2.21e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.31	3.35e-03	GO:0016874	ligase activity
1.32	3.41e-03	GO:0042803	protein homodimerization activity
1.38	7.36e-03	GO:0005083	small GTPase regulator activity
1.41	1.21e-02	GO:0019787	small conjugating protein ligase activity
1.25	1.28e-02	GO:0046983	protein dimerization activity
1.23	1.67e-02	GO:0016788	hydrolase activity, acting on ester bonds
1.55	2.74e-02	GO:0035091	phosphatidylinositol binding
1.38	4.43e-02	GO:0019900	kinase binding