Motif ID: PAX5.p2

Z-value: 1.295


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.467.0e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_133923992 2.568 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr3_-_133923906 2.346 NM_153240
NPHP3
nephronophthisis 3 (adolescent)
chr19_+_61742111 1.987 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr17_-_78199384 1.297 NM_019613
WDR45L
WDR45-like
chr14_-_52487558 1.279 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr2_+_235525355 1.248 NM_014521
SH3BP4
SH3-domain binding protein 4
chr1_+_24944554 1.135 CLIC4
chloride intracellular channel 4
chr2_-_98713862 1.124 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_179024002 1.057 NM_003690
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_69212192 1.054 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr2_-_98714020 1.054 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_52094613 1.041 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr13_+_27094018 1.033 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr1_-_109386112 1.015 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chrX_+_18353623 1.002 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr14_-_52487386 0.981 FERMT2
fermitin family member 2
chr6_-_109911125 0.973 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr20_-_3336586 0.961 C20orf194
chromosome 20 open reading frame 194
chr2_-_215382537 0.955 NM_000465
BARD1
BRCA1 associated RING domain 1
chr16_-_3225360 0.922 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr1_+_24944493 0.908 CLIC4
chloride intracellular channel 4
chr2_+_56264627 0.898 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr18_+_11971443 0.892 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_+_113734997 0.870 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr18_+_11971421 0.867 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr6_-_109911015 0.852 ZBTB24
zinc finger and BTB domain containing 24
chr6_+_132170847 0.841 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr3_-_127677451 0.838 NM_001040653
NM_025112
ZXDC

ZXD family zinc finger C

chr8_+_25098296 0.831 DOCK5
dedicator of cytokinesis 5
chr12_-_13044448 0.830 HEBP1
heme binding protein 1
chr12_-_13044314 0.829 HEBP1
heme binding protein 1
chr8_+_25098171 0.828 NM_024940
DOCK5
dedicator of cytokinesis 5
chr9_-_36391149 0.825 NM_194330
RNF38
ring finger protein 38
chr20_-_51644187 0.818 ZNF217
zinc finger protein 217
chr12_-_13044467 0.815 NM_015987
HEBP1
heme binding protein 1
chr11_+_101485946 0.808 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr6_-_99502528 0.796 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chr10_-_12124778 0.795 NM_015542
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_-_108860740 0.791 NM_005443
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr2_+_233270286 0.789 GIGYF2
GRB10 interacting GYF protein 2
chr10_+_171410 0.781 ZMYND11
zinc finger, MYND-type containing 11
chr17_+_26060617 0.778


chr9_-_33157300 0.769 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr1_-_115433570 0.766 NM_005725
TSPAN2
tetraspanin 2
chr1_-_93919789 0.764 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr2_-_11402150 0.762 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr10_-_35143900 0.754 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr14_+_103251798 0.754 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr3_-_198509276 0.749 DLG1
discs, large homolog 1 (Drosophila)
chr13_+_26029879 0.749 WASF3
WAS protein family, member 3
chr1_+_181259317 0.746


chr12_-_74711642 0.735 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_151171190 0.735 NM_002628
NM_053024
PFN2

profilin 2

chr8_-_99906944 0.732 NM_006281
STK3
serine/threonine kinase 3
chr16_+_67131161 0.732 NM_133458
ZFP90
zinc finger protein 90 homolog (mouse)
chr8_-_67687980 0.729 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr2_+_238265519 0.728 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr21_+_45318861 0.717 NM_001112
NM_001160230
NM_015833
NM_015834
ADARB1



adenosine deaminase, RNA-specific, B1



chr2_+_24126140 0.713 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr16_+_67130616 0.691 ZFP90
zinc finger protein 90 homolog (mouse)
chr1_+_24944346 0.688 NM_013943
CLIC4
chloride intracellular channel 4
chr13_+_43351968 0.688 NM_153218
C13orf31
chromosome 13 open reading frame 31
chr17_+_75849221 0.683 NM_020914
NM_020954
RNF213

ring finger protein 213

chr1_-_233879617 0.682 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_+_86943103 0.673 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr7_-_28186671 0.670 JAZF1
JAZF zinc finger 1
chr10_-_15250616 0.661 NM_004808
NMT2
N-myristoyltransferase 2
chr18_+_54489763 0.647 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr11_+_109468734 0.645 ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_86943074 0.645 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr13_-_113066366 0.644 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr10_-_62431203 0.639 RHOBTB1
Rho-related BTB domain containing 1
chr18_+_11971552 0.636 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr14_-_50367513 0.634 NM_016350
NM_020921
NM_182944
NM_182946
NIN



ninein (GSK3B interacting protein)



chr5_+_135392482 0.634 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr9_+_96807107 0.634 C9orf3
chromosome 9 open reading frame 3
chr13_+_97426713 0.632 IPO5
importin 5
chr3_+_32255158 0.627 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr4_-_158111995 0.626 NM_016205
PDGFC
platelet derived growth factor C
chr3_-_187025501 0.625 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr8_-_13035102 0.624 NM_006094
DLC1
deleted in liver cancer 1
chr10_-_135036805 0.620 NM_004092
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr13_-_43351825 0.620 NM_144974
CCDC122
coiled-coil domain containing 122
chr16_-_56789142 0.617 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr18_+_53862744 0.608 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_177837540 0.603 NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr18_+_9126742 0.593 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr2_-_99472843 0.592 REV1
REV1 homolog (S. cerevisiae)
chr5_+_122138677 0.592 SNX2
sorting nexin 2
chr10_+_124124083 0.589 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_-_23683214 0.587 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr21_+_46473494 0.585 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr20_-_23566325 0.579 NM_000099
CST3
cystatin C
chr5_-_114660139 0.579 NM_001040440
CCDC112
coiled-coil domain containing 112
chr1_-_23683308 0.578 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr2_-_158440587 0.577 NM_001111067
ACVR1
activin A receptor, type I
chr7_-_105712565 0.576 NAMPT
nicotinamide phosphoribosyltransferase
chr2_+_219354948 0.575 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr2_+_112529270 0.573 NM_032824
TMEM87B
transmembrane protein 87B
chr6_-_114398946 0.573 HDAC2
histone deacetylase 2
chr15_-_27901828 0.569 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr17_-_15407497 0.568 NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 read-through transcript
family with sequence similarity 18, member B2

chr5_+_122138661 0.568 SNX2
sorting nexin 2
chr13_-_27092677 0.568 NM_153371
LNX2
ligand of numb-protein X 2
chr5_+_122138636 0.566 NM_003100
SNX2
sorting nexin 2
chr14_+_55116549 0.565 NM_001079521
NM_001079522
NM_004986
NM_182926
KTN1



kinectin 1 (kinesin receptor)



chrX_+_17665483 0.562 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr7_+_115926855 0.562 CAV2
caveolin 2
chrX_-_132947141 0.561 GPC3
glypican 3
chr13_-_113066202 0.560 GRTP1
growth hormone regulated TBC protein 1
chr18_+_12937972 0.560 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr13_+_27094024 0.557 NM_015972
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr9_+_494661 0.555 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr6_+_17389752 0.549 NM_001143942
RBM24
RNA binding motif protein 24
chr4_+_3264509 0.548 RGS12
regulator of G-protein signaling 12
chr1_+_86942874 0.547 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr2_-_179023600 0.547 NM_001139518
NM_001139517
PRKRA

protein kinase, interferon-inducible double stranded RNA dependent activator

chr6_+_132170888 0.546 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr20_-_39680405 0.546 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr3_-_187025438 0.543 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr15_+_54998144 0.542 TCF12
transcription factor 12
chr6_-_99502495 0.538 FBXL4
F-box and leucine-rich repeat protein 4
chr17_-_74432800 0.535 TIMP2
TIMP metallopeptidase inhibitor 2
chr7_-_107883929 0.535 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr1_+_9275542 0.534 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr3_-_151171576 0.533 PFN2
profilin 2
chr13_+_26029799 0.533 NM_006646
WASF3
WAS protein family, member 3
chr18_+_27925923 0.533 RNF138
ring finger protein 138
chr2_-_114230455 0.530 SLC35F5
solute carrier family 35, member F5
chr8_-_71478041 0.530 NCOA2
nuclear receptor coactivator 2
chr6_-_13819463 0.529 RANBP9
RAN binding protein 9
chr6_-_101435727 0.529 ASCC3
activating signal cointegrator 1 complex subunit 3
chr18_+_12938010 0.527 SEH1L
SEH1-like (S. cerevisiae)
chr2_-_97572580 0.526


chr12_-_93568336 0.523 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr14_+_102128844 0.523 NM_015156
RCOR1
REST corepressor 1
chr15_-_53667800 0.521 PYGO1
pygopus homolog 1 (Drosophila)
chr4_-_170428564 0.520 SH3RF1
SH3 domain containing ring finger 1
chr3_-_123716471 0.518 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr2_+_10101081 0.518 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr2_-_16710551 0.514 NM_030797
FAM49A
family with sequence similarity 49, member A
chr8_+_38208165 0.514 NM_001164234
NM_015214
DDHD2

DDHD domain containing 2

chr6_+_160068553 0.513 WTAP
Wilms tumor 1 associated protein
chr17_-_72218535 0.511 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr20_-_55718351 0.511 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_-_171814026 0.510 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr4_-_102487649 0.509 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr13_+_110565587 0.509 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr18_+_54489798 0.509 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_95188989 0.509 NM_032788
ZNF514
zinc finger protein 514
chr3_-_127677400 0.508 ZXDC
ZXD family zinc finger C
chr4_-_37364327 0.507 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr1_+_9275518 0.506 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_-_50375143 0.503 NM_018728
MYO5C
myosin VC
chr6_-_119297851 0.502 MCM9
minichromosome maintenance complex component 9
chr17_-_60088773 0.500 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr18_-_43711143 0.498 SMAD2
SMAD family member 2
chr2_+_61146542 0.497 KIAA1841
KIAA1841
chr8_-_102287083 0.497 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr16_-_79687367 0.494 NM_004483
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr12_-_74711474 0.489 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr14_-_52232316 0.486 ERO1L
ERO1-like (S. cerevisiae)
chr4_-_177950658 0.485 NM_005429
VEGFC
vascular endothelial growth factor C
chr3_+_171558188 0.484 SKIL
SKI-like oncogene
chr14_-_38971370 0.481 NM_203301
FBXO33
F-box protein 33
chr5_+_79986254 0.479 MSH3
mutS homolog 3 (E. coli)
chr11_-_86343859 0.479 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr2_-_25328452 0.478 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr2_+_238265617 0.477 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr14_+_56927014 0.477 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_142664490 0.476 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr4_+_99401543 0.476 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr3_+_23961739 0.476 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr12_-_103055924 0.476 NM_006166
NFYB
nuclear transcription factor Y, beta
chr12_+_102982365 0.476 NM_013320
HCFC2
host cell factor C2
chr20_+_60130963 0.474 LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr14_+_99329198 0.474 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr18_+_53862386 0.472 NM_001144967
NM_015277
NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like

chr7_+_77004267 0.471 PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_-_72170533 0.470 STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_+_160068531 0.470 WTAP
Wilms tumor 1 associated protein
chr12_+_3056781 0.469 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr6_+_117910472 0.469 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr2_-_97978421 0.466 NM_015348
TMEM131
transmembrane protein 131
chr3_+_171558215 0.466 SKIL
SKI-like oncogene
chr13_+_95002942 0.465 NM_006984
CLDN10
claudin 10
chr4_-_53220073 0.463 NM_022832
USP46
ubiquitin specific peptidase 46
chr1_-_93199586 0.462 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr15_-_20637731 0.462 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_131021169 0.462 NM_016623
FAM49B
family with sequence similarity 49, member B
chr8_-_131021078 0.461 FAM49B
family with sequence similarity 49, member B
chr10_+_124124196 0.461 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_+_160068598 0.459 NM_152857
WTAP
Wilms tumor 1 associated protein
chr18_+_54489658 0.459 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_+_70459686 0.458 SRSF11
serine/arginine-rich splicing factor 11
chr12_+_2938703 0.457 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr7_+_55054152 0.456 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr10_+_121475628 0.455 INPP5F
inositol polyphosphate-5-phosphatase F
chr18_-_63334902 0.454 NM_032160
DSEL
dermatan sulfate epimerase-like
chr12_+_67290881 0.454 NM_001010942
NM_015646
RAP1B

RAP1B, member of RAS oncogene family


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 2.32e-31 GO:0044237 cellular metabolic process
1.23 3.86e-28 GO:0044260 cellular macromolecule metabolic process
1.17 5.63e-25 GO:0044238 primary metabolic process
1.15 3.05e-24 GO:0008152 metabolic process
1.09 8.34e-24 GO:0009987 cellular process
1.19 6.96e-22 GO:0043170 macromolecule metabolic process
1.34 1.22e-20 GO:0006464 protein modification process
1.32 1.30e-19 GO:0043412 macromolecule modification
1.27 7.08e-19 GO:0044267 cellular protein metabolic process
1.12 2.24e-13 GO:0050794 regulation of cellular process
1.21 2.95e-13 GO:0019538 protein metabolic process
1.11 8.56e-13 GO:0050789 regulation of biological process
1.10 1.61e-12 GO:0065007 biological regulation
1.30 4.34e-11 GO:0009966 regulation of signal transduction
1.24 4.64e-11 GO:0048523 negative regulation of cellular process
1.34 3.98e-10 GO:0006793 phosphorus metabolic process
1.34 3.98e-10 GO:0006796 phosphate metabolic process
1.20 6.58e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 1.01e-09 GO:0016043 cellular component organization
1.31 1.22e-09 GO:0044248 cellular catabolic process
1.18 2.40e-09 GO:0034641 cellular nitrogen compound metabolic process
1.16 3.43e-09 GO:0071840 cellular component organization or biogenesis
1.17 5.63e-09 GO:0006807 nitrogen compound metabolic process
1.25 8.51e-09 GO:0023051 regulation of signaling
1.26 1.75e-08 GO:0009056 catabolic process
1.40 2.91e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.14 4.50e-08 GO:0019222 regulation of metabolic process
1.20 5.02e-08 GO:0048519 negative regulation of biological process
1.24 1.02e-07 GO:0006996 organelle organization
1.34 3.38e-07 GO:0046907 intracellular transport
1.30 3.64e-07 GO:0007049 cell cycle
1.18 3.82e-07 GO:0071842 cellular component organization at cellular level
1.26 4.11e-07 GO:0051641 cellular localization
1.15 4.30e-07 GO:0060255 regulation of macromolecule metabolic process
1.42 4.35e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.15 5.27e-07 GO:0031323 regulation of cellular metabolic process
1.17 8.17e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.19 8.31e-07 GO:0090304 nucleic acid metabolic process
1.14 2.10e-06 GO:0080090 regulation of primary metabolic process
1.25 2.86e-06 GO:0033036 macromolecule localization
1.27 4.47e-06 GO:0051246 regulation of protein metabolic process
1.36 5.91e-06 GO:0009057 macromolecule catabolic process
1.39 7.00e-06 GO:0044265 cellular macromolecule catabolic process
1.12 8.42e-06 GO:0051716 cellular response to stimulus
1.73 9.72e-06 GO:0016311 dephosphorylation
1.32 1.02e-05 GO:0006468 protein phosphorylation
1.27 1.50e-05 GO:0032268 regulation of cellular protein metabolic process
1.46 1.62e-05 GO:0018193 peptidyl-amino acid modification
1.17 1.85e-05 GO:0048522 positive regulation of cellular process
1.26 2.26e-05 GO:0008104 protein localization
1.26 3.06e-05 GO:0043067 regulation of programmed cell death
1.26 4.03e-05 GO:0010941 regulation of cell death
1.26 6.72e-05 GO:0042981 regulation of apoptosis
1.16 6.93e-05 GO:0044249 cellular biosynthetic process
1.24 8.00e-05 GO:0051649 establishment of localization in cell
1.72 8.05e-05 GO:0006470 protein dephosphorylation
1.29 9.35e-05 GO:0051128 regulation of cellular component organization
1.15 1.10e-04 GO:0048518 positive regulation of biological process
1.15 1.20e-04 GO:0009058 biosynthetic process
1.21 1.33e-04 GO:0065009 regulation of molecular function
1.29 1.55e-04 GO:0031399 regulation of protein modification process
1.28 2.19e-04 GO:0016310 phosphorylation
1.61 2.51e-04 GO:0051493 regulation of cytoskeleton organization
1.27 2.67e-04 GO:0033554 cellular response to stress
1.27 2.80e-04 GO:0045184 establishment of protein localization
1.29 3.38e-04 GO:0016192 vesicle-mediated transport
1.26 4.21e-04 GO:0016265 death
1.26 5.11e-04 GO:0008219 cell death
1.12 5.73e-04 GO:0007165 signal transduction
1.18 6.03e-04 GO:0034645 cellular macromolecule biosynthetic process
1.17 6.83e-04 GO:0048583 regulation of response to stimulus
1.26 8.26e-04 GO:0015031 protein transport
1.51 8.26e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.43 8.28e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.18 9.67e-04 GO:0009059 macromolecule biosynthetic process
1.56 1.12e-03 GO:0051169 nuclear transport
1.28 1.13e-03 GO:0012501 programmed cell death
1.56 1.25e-03 GO:0006913 nucleocytoplasmic transport
1.30 1.32e-03 GO:0051726 regulation of cell cycle
1.11 1.32e-03 GO:0023052 signaling
1.41 1.66e-03 GO:0044257 cellular protein catabolic process
1.33 1.80e-03 GO:0034613 cellular protein localization
1.32 1.96e-03 GO:0070727 cellular macromolecule localization
1.28 2.13e-03 GO:0019220 regulation of phosphate metabolic process
1.28 2.13e-03 GO:0051174 regulation of phosphorus metabolic process
1.40 2.33e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.20 2.41e-03 GO:0035556 intracellular signal transduction
1.17 3.16e-03 GO:0016070 RNA metabolic process
1.61 3.22e-03 GO:0051099 positive regulation of binding
1.40 3.28e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.40 3.68e-03 GO:0019941 modification-dependent protein catabolic process
1.27 4.24e-03 GO:0006915 apoptosis
1.25 4.32e-03 GO:0022402 cell cycle process
1.38 4.79e-03 GO:0030163 protein catabolic process
1.32 4.95e-03 GO:0051338 regulation of transferase activity
1.28 6.26e-03 GO:0001932 regulation of protein phosphorylation
1.39 7.45e-03 GO:0033043 regulation of organelle organization
1.34 8.80e-03 GO:0043066 negative regulation of apoptosis
1.33 1.01e-02 GO:0060548 negative regulation of cell death
1.31 1.14e-02 GO:0043549 regulation of kinase activity
1.33 1.17e-02 GO:0043069 negative regulation of programmed cell death
1.28 1.40e-02 GO:0000278 mitotic cell cycle
1.26 1.76e-02 GO:0042325 regulation of phosphorylation
1.40 1.77e-02 GO:0032446 protein modification by small protein conjugation
1.34 1.80e-02 GO:0006886 intracellular protein transport
1.37 1.82e-02 GO:0070647 protein modification by small protein conjugation or removal
1.31 1.83e-02 GO:0045859 regulation of protein kinase activity
1.29 2.01e-02 GO:0010942 positive regulation of cell death
1.37 2.29e-02 GO:0051098 regulation of binding
1.25 2.31e-02 GO:0022403 cell cycle phase
1.12 2.42e-02 GO:0010468 regulation of gene expression
1.20 2.51e-02 GO:0010646 regulation of cell communication
1.22 2.58e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.35 2.72e-02 GO:0051301 cell division
1.20 2.73e-02 GO:0022607 cellular component assembly
2.61 2.95e-02 GO:0048008 platelet-derived growth factor receptor signaling pathway
1.29 3.01e-02 GO:0043068 positive regulation of programmed cell death
1.19 3.27e-02 GO:0050790 regulation of catalytic activity
1.59 3.32e-02 GO:0043388 positive regulation of DNA binding
1.89 3.41e-02 GO:0046519 sphingoid metabolic process
1.21 3.52e-02 GO:0009892 negative regulation of metabolic process
1.12 3.61e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.12 3.66e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 3.96e-02 GO:0016568 chromatin modification
1.34 4.03e-02 GO:0044419 interspecies interaction between organisms
1.18 4.19e-02 GO:0044085 cellular component biogenesis
1.10 4.55e-02 GO:0051179 localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 6.53e-55 GO:0005622 intracellular
1.13 3.04e-54 GO:0044424 intracellular part
1.17 1.29e-42 GO:0005737 cytoplasm
1.16 6.49e-42 GO:0043227 membrane-bounded organelle
1.15 1.59e-41 GO:0043231 intracellular membrane-bounded organelle
1.14 1.08e-40 GO:0043226 organelle
1.14 1.47e-40 GO:0043229 intracellular organelle
1.20 5.78e-34 GO:0044444 cytoplasmic part
1.19 5.24e-27 GO:0005634 nucleus
1.31 1.13e-20 GO:0005829 cytosol
1.15 2.99e-16 GO:0044422 organelle part
1.14 1.24e-15 GO:0044446 intracellular organelle part
1.24 1.39e-12 GO:0044428 nuclear part
1.03 1.31e-11 GO:0044464 cell part
1.03 1.48e-11 GO:0005623 cell
1.21 3.86e-10 GO:0070013 intracellular organelle lumen
1.20 8.71e-10 GO:0031974 membrane-enclosed lumen
1.20 1.80e-09 GO:0043233 organelle lumen
1.22 1.12e-08 GO:0031981 nuclear lumen
1.26 2.70e-08 GO:0005654 nucleoplasm
1.67 3.86e-07 GO:0031252 cell leading edge
1.21 7.41e-07 GO:0012505 endomembrane system
1.70 1.64e-06 GO:0005912 adherens junction
1.65 5.08e-06 GO:0070161 anchoring junction
1.25 1.36e-05 GO:0005794 Golgi apparatus
1.29 2.51e-05 GO:0044451 nucleoplasm part
1.41 4.51e-05 GO:0048471 perinuclear region of cytoplasm
1.16 4.67e-05 GO:0031090 organelle membrane
1.29 8.49e-05 GO:0015630 microtubule cytoskeleton
1.72 1.32e-04 GO:0030055 cell-substrate junction
1.73 3.29e-04 GO:0005925 focal adhesion
1.46 3.64e-04 GO:0005635 nuclear envelope
1.70 4.37e-04 GO:0005924 cell-substrate adherens junction
1.12 1.11e-03 GO:0043234 protein complex
1.37 1.41e-03 GO:0005815 microtubule organizing center
1.44 2.24e-03 GO:0005813 centrosome
1.12 3.93e-03 GO:0043228 non-membrane-bounded organelle
1.12 3.93e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.16 4.46e-03 GO:0005856 cytoskeleton
1.26 5.55e-03 GO:0044431 Golgi apparatus part
1.29 7.53e-03 GO:0000139 Golgi membrane
1.23 8.13e-03 GO:0031967 organelle envelope
1.17 8.15e-03 GO:0005739 mitochondrion
1.23 9.71e-03 GO:0031975 envelope
1.25 1.03e-02 GO:0030054 cell junction
1.39 1.66e-02 GO:0016323 basolateral plasma membrane
1.65 2.15e-02 GO:0030027 lamellipodium
1.64 3.61e-02 GO:0046930 pore complex
1.61 3.86e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 7.09e-31 GO:0005515 protein binding
1.08 1.69e-25 GO:0005488 binding
1.12 4.67e-10 GO:0003824 catalytic activity
1.21 5.66e-10 GO:0000166 nucleotide binding
1.32 2.97e-08 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.46 3.36e-08 GO:0019904 protein domain specific binding
1.34 4.71e-08 GO:0016301 kinase activity
1.21 9.91e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.21 1.14e-07 GO:0017076 purine nucleotide binding
1.21 1.26e-07 GO:0032553 ribonucleotide binding
1.21 1.26e-07 GO:0032555 purine ribonucleotide binding
1.34 1.76e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.44 2.62e-07 GO:0004674 protein serine/threonine kinase activity
1.22 3.88e-07 GO:0030554 adenyl nucleotide binding
1.22 5.59e-07 GO:0032559 adenyl ribonucleotide binding
1.22 7.46e-07 GO:0005524 ATP binding
1.36 1.31e-06 GO:0004672 protein kinase activity
1.69 1.93e-06 GO:0004721 phosphoprotein phosphatase activity
1.20 6.68e-06 GO:0016740 transferase activity
1.39 6.89e-06 GO:0030695 GTPase regulator activity
1.37 1.91e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.49 2.69e-05 GO:0032403 protein complex binding
1.29 4.76e-05 GO:0019899 enzyme binding
1.48 1.75e-04 GO:0016791 phosphatase activity
1.38 2.27e-04 GO:0000988 protein binding transcription factor activity
1.38 2.27e-04 GO:0000989 transcription factor binding transcription factor activity
1.43 2.65e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.43 2.98e-04 GO:0008134 transcription factor binding
1.38 3.18e-04 GO:0003712 transcription cofactor activity
1.75 3.84e-04 GO:0004725 protein tyrosine phosphatase activity
1.26 5.69e-04 GO:0042802 identical protein binding
1.56 7.97e-04 GO:0000287 magnesium ion binding
1.38 9.76e-04 GO:0042578 phosphoric ester hydrolase activity
1.43 1.03e-03 GO:0016881 acid-amino acid ligase activity
1.22 1.64e-03 GO:0030234 enzyme regulator activity
1.54 2.21e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.31 3.35e-03 GO:0016874 ligase activity
1.32 3.41e-03 GO:0042803 protein homodimerization activity
1.38 7.36e-03 GO:0005083 small GTPase regulator activity
1.41 1.21e-02 GO:0019787 small conjugating protein ligase activity
1.25 1.28e-02 GO:0046983 protein dimerization activity
1.23 1.67e-02 GO:0016788 hydrolase activity, acting on ester bonds
1.55 2.74e-02 GO:0035091 phosphatidylinositol binding
1.38 4.43e-02 GO:0019900 kinase binding