Motif ID: PRDM1.p3

Z-value: 1.729


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_106640881-0.263.3e-01Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_16717887 2.332 BNC2
basonuclin 2
chr4_+_142777172 1.621 NM_000585
NM_172174
IL15

interleukin 15

chr17_+_6600080 1.549 XAF1
XIAP associated factor 1
chr3_-_115825742 1.367 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_8518508 1.247 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr12_+_6431437 1.204 NM_018009
TAPBPL
TAP binding protein-like
chr1_+_110254755 1.182 NM_000757
NM_172210
NM_172211
NM_172212
CSF1



colony stimulating factor 1 (macrophage)



chr1_+_110254979 1.124 CSF1
colony stimulating factor 1 (macrophage)
chr4_-_186814852 1.082 SORBS2
sorbin and SH3 domain containing 2
chr12_+_25096472 1.070 NM_006152
LRMP
lymphoid-restricted membrane protein
chr8_-_29176490 1.063 NM_015254
KIF13B
kinesin family member 13B
chr22_-_28972683 1.020 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_-_112682401 1.002 LAMA4
laminin, alpha 4
chr11_-_40272239 0.988 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr4_-_186815116 0.973 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr3_+_8518539 0.973 LMCD1
LIM and cysteine-rich domains 1
chr2_+_205118801 0.969 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr16_+_55580910 0.936 NM_032206
NLRC5
NLR family, CARD domain containing 5
chrX_-_100920493 0.923 GK
glycerol kinase
chrX_+_10084984 0.921 NM_001830
CLCN4
chloride channel 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
50.64 3.42e-04 GO:0002483 antigen processing and presentation of endogenous peptide antigen
50.64 3.42e-04 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
36.17 2.34e-03 GO:0019883 antigen processing and presentation of endogenous antigen
19.48 4.43e-02 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
12.25 2.30e-07 GO:0060337 type I interferon-mediated signaling pathway
12.25 2.30e-07 GO:0071357 cellular response to type I interferon
12.06 2.80e-07 GO:0034340 response to type I interferon
6.63 9.69e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
5.51 4.30e-05 GO:0019221 cytokine-mediated signaling pathway
5.35 1.17e-03 GO:0009615 response to virus
5.28 3.01e-05 GO:0071345 cellular response to cytokine stimulus
3.81 3.14e-03 GO:0034097 response to cytokine stimulus
3.48 3.06e-03 GO:0045087 innate immune response
3.00 4.13e-02 GO:0051707 response to other organism
2.94 5.38e-05 GO:0006955 immune response
2.94 6.65e-04 GO:0071310 cellular response to organic substance
2.70 3.29e-03 GO:0002682 regulation of immune system process
2.58 6.72e-04 GO:0051704 multi-organism process
2.56 2.74e-03 GO:0006508 proteolysis
2.56 2.74e-03 GO:0006952 defense response

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
63.29 4.32e-02 GO:0071797 LUBAC complex
12.66 4.20e-02 GO:0005839 proteasome core complex
7.17 3.14e-02 GO:0035770 RNA granule
7.04 1.02e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
4.11 9.36e-03 GO:0005126 cytokine receptor binding
2.46 3.40e-02 GO:0008233 peptidase activity
2.03 4.32e-02 GO:0001071 nucleic acid binding transcription factor activity
2.03 4.32e-02 GO:0003700 sequence-specific DNA binding transcription factor activity