Motif ID: CTCF.p2

Z-value: 1.519


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_66153810-0.155.7e-01Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_2330712 1.428 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr9_+_115957537 1.422 COL27A1
collagen, type XXVII, alpha 1
chr9_-_93751900 1.377 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr16_-_2330738 1.354 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr22_-_20637188 1.123 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr16_-_2330594 1.121 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr3_+_38010618 1.023 VILL
villin-like
chr22_-_20637212 0.991 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr7_-_100009205 0.903 NM_001168682
SAP25
sin3A-binding protein 25
chr11_+_117983515 0.892 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr10_-_79459296 0.882 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr19_+_52908412 0.876 NM_014601
EHD2
EH-domain containing 2
chr9_+_130005429 0.873 NM_001005336
NM_004408
DNM1

dynamin 1

chr3_+_49183983 0.838 NM_173546
KLHDC8B
kelch domain containing 8B
chr11_+_63775572 0.826 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr10_-_79459170 0.825 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr5_+_53849396 0.816 SNX18
sorting nexin 18
chr7_-_22506320 0.803 NM_001164460
NM_207342
MGC87042

STEAP family protein MGC87042

chr19_-_4351470 0.787 NM_003025
SH3GL1
SH3-domain GRB2-like 1
chr17_-_75624048 0.786 NM_019020
TBC1D16
TBC1 domain family, member 16
chr5_+_53849518 0.779 SNX18
sorting nexin 18
chr11_-_44928803 0.777 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr22_+_18085990 0.776 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr7_-_100262971 0.755 NM_004444
EPHB4
EPH receptor B4
chr7_+_72720256 0.737 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr3_+_47841478 0.731 DHX30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr7_+_72720093 0.704 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr22_+_18085891 0.675 SEPT5
septin 5
chr1_+_161308318 0.672 NM_001113380
RGS4
regulator of G-protein signaling 4
chr11_-_65860450 0.663 NM_004292
RIN1
Ras and Rab interactor 1
chr3_-_129694717 0.656 NM_032638
GATA2
GATA binding protein 2
chr19_-_4351357 0.656 SH3GL1
SH3-domain GRB2-like 1
chr17_-_24078075 0.652 NM_001160407
TLCD1
TLC domain containing 1
chr7_-_38341697 0.649 TRGV7
T cell receptor gamma variable 7 pseudogene
chr12_+_47494882 0.646 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr9_+_130005489 0.646 DNM1
dynamin 1
chr1_+_28717349 0.644 RCC1
regulator of chromosome condensation 1
chrX_-_134764397 0.642 NM_001017436
CT45A3
CT45A4
CT45A2
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A2
chr9_+_130222511 0.640 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_94147616 0.640 GCLM
glutamate-cysteine ligase, modifier subunit
chr9_+_130222943 0.637 CERCAM
cerebral endothelial cell adhesion molecule
chr9_+_130005487 0.630 DNM1
dynamin 1
chr17_-_59342319 0.624 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr5_+_148501178 0.623 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr11_-_65962836 0.619 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr14_+_22375632 0.619 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr19_+_5774817 0.613 NM_004558
NRTN
neurturin
chr19_+_60505205 0.604 BRSK1
BR serine/threonine kinase 1
chr17_+_1905104 0.599 NM_006497
HIC1
hypermethylated in cancer 1
chr5_-_146813343 0.596 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr19_+_10388448 0.593 PDE4A
phosphodiesterase 4A, cAMP-specific
chrX_+_134711153 0.589 NM_001017435
CT45A3
CT45A2
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A2
chr9_+_138680064 0.588 EGFL7
EGF-like-domain, multiple 7
chr14_-_90352395 0.584


chrX_+_46938246 0.582 UBA1
ubiquitin-like modifier activating enzyme 1
chr2_-_27162868 0.569


chr18_+_8599670 0.562


chr1_-_32054164 0.554 NM_144569
SPOCD1
SPOC domain containing 1
chr14_-_90352513 0.553 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chr16_-_730889 0.546 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr9_-_139262009 0.544 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr1_+_27591738 0.538 NM_005281
GPR3
G protein-coupled receptor 3
chr11_+_61204392 0.527 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr10_+_102749222 0.524 LZTS2
leucine zipper, putative tumor suppressor 2
chr14_+_22375656 0.520 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr8_+_43067805 0.513 NM_032237
SGK196
protein kinase-like protein SgK196
chr9_-_139060416 0.512 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr11_+_66790465 0.511 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr8_+_43067817 0.501


chr9_-_38059207 0.499 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chrX_-_134798808 0.498 NM_001017438
CT45A3
CT45A4
CT45A5
CT45A6
CT45A1
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A5
cancer/testis antigen family 45, member A6
cancer/testis antigen family 45, member A1
chr5_+_180514548 0.495 NM_206880
OR2V2
olfactory receptor, family 2, subfamily V, member 2
chr10_+_72102563 0.491 NM_080722
NM_139155
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr11_+_62136788 0.489 NM_000327
ROM1
retinal outer segment membrane protein 1
chr3_-_49942198 0.489 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr6_+_35418346 0.489 PPARD
peroxisome proliferator-activated receptor delta
chrX_+_49480643 0.487 NM_007003
PAGE4
P antigen family, member 4 (prostate associated)
chr19_-_52426055 0.487 NM_014417
BBC3
BCL2 binding component 3
chr1_+_17121012 0.484 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chrX_+_46938215 0.479 UBA1
ubiquitin-like modifier activating enzyme 1
chr5_+_53849251 0.475 NM_001145427
NM_001102575
NM_052870
SNX18


sorting nexin 18


chr1_-_6537139 0.474 NOL9
nucleolar protein 9
chr9_+_33614214 0.474 ANXA2P2
annexin A2 pseudogene 2
chr1_-_17638797 0.471 NM_018715
RCC2
regulator of chromosome condensation 2
chr6_+_139055244 0.470 FLJ46906
hypothetical LOC441172
chr16_+_170334 0.463 NM_005331
HBQ1
hemoglobin, theta 1
chr14_+_22375753 0.463 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr19_-_1799447 0.462 NM_020695
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr9_+_130941508 0.461


chr19_-_54231884 0.456 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr9_-_100598315 0.454 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr12_-_32800064 0.448 NM_001040436
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chrX_-_117003310 0.446 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr14_+_22375747 0.445 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr1_+_16639753 0.444 NM_001145277
NM_001145278
NM_018090
NECAP2


NECAP endocytosis associated 2


chr9_-_129993615 0.440 NM_001131016
NM_001131017
NM_001131018
CIZ1


CDKN1A interacting zinc finger protein 1


chr19_-_46551607 0.439 TGFB1
transforming growth factor, beta 1
chr21_+_44549486 0.439 PFKL
phosphofructokinase, liver
chr22_-_17512097 0.438 DGCR14
DiGeorge syndrome critical region gene 14
chr9_+_130838720 0.438 FAM73B
family with sequence similarity 73, member B
chr10_+_73241645 0.431 NM_001171935
NM_001171936
CDH23

cadherin-related 23

chr11_+_66790505 0.429 ADRBK1
adrenergic, beta, receptor kinase 1
chr5_-_179267426 0.427 TBC1D9B
TBC1 domain family, member 9B (with GRAM domain)
chr5_-_179267456 0.425 NM_015043
NM_198868
TBC1D9B

TBC1 domain family, member 9B (with GRAM domain)

chr1_-_113051545 0.425 NM_001042678
NM_175744
RHOC

ras homolog gene family, member C

chr1_+_16639805 0.425 NECAP2
NECAP endocytosis associated 2
chrX_-_131181141 0.422 RAP2C
RAP2C, member of RAS oncogene family
chr6_-_18230829 0.422 NM_198586
NHLRC1
NHL repeat containing 1
chr7_-_38355949 0.421


chr10_+_99322187 0.421 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr17_+_45911216 0.420 RSAD1
radical S-adenosyl methionine domain containing 1
chr19_+_4742756 0.418 FEM1A
fem-1 homolog a (C. elegans)
chr8_-_145521297 0.418 DGAT1
diacylglycerol O-acyltransferase 1
chr1_-_40140126 0.418 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr19_-_18913011 0.414 HOMER3
homer homolog 3 (Drosophila)
chr1_-_170679830 0.413 PIGC
phosphatidylinositol glycan anchor biosynthesis, class C
chr12_+_6903886 0.413 NM_001007026
ATN1
atrophin 1
chr22_+_18388602 0.412 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr1_-_36338436 0.411 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr12_+_103133631 0.410 NM_001093771
TXNRD1
thioredoxin reductase 1
chr4_+_152417774 0.410 NM_183375
PRSS48
protease, serine, 48
chr19_-_18913017 0.409 HOMER3
homer homolog 3 (Drosophila)
chr6_-_43531763 0.404 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr20_+_56848127 0.404 GNAS
GNAS complex locus
chr1_-_113051248 0.399 RHOC
ras homolog gene family, member C
chr19_+_54669283 0.397 NM_001459
FLT3LG
fms-related tyrosine kinase 3 ligand
chr1_-_94147537 0.397 GCLM
glutamate-cysteine ligase, modifier subunit
chrX_+_46938178 0.396 UBA1
ubiquitin-like modifier activating enzyme 1
chr16_+_30903963 0.394 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr19_-_1799359 0.392 REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr10_-_49534304 0.391 ARHGAP22
Rho GTPase activating protein 22
chr9_-_135014343 0.390 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr19_+_18560494 0.390 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr3_-_129852182 0.390 RPN1
ribophorin I
chr5_-_136862786 0.388 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_+_246167115 0.388 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr2_-_39310176 0.387 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr1_-_153412356 0.384 NM_173852
KRTCAP2
keratinocyte associated protein 2
chr19_+_60857227 0.384 NM_001012478
NM_007279
U2AF2

U2 small nuclear RNA auxiliary factor 2

chr1_+_221966951 0.383 CAPN2
calpain 2, (m/II) large subunit
chr1_+_16639822 0.382 NECAP2
NECAP endocytosis associated 2
chr4_-_1980500 0.382 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr7_+_111908143 0.382 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr11_+_64705261 0.381 NM_001198868
CAPN1
calpain 1, (mu/I) large subunit
chr1_-_6684465 0.380 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr12_+_92487728 0.380 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr1_-_224662156 0.380 PARP1
poly (ADP-ribose) polymerase 1
chr22_+_18388633 0.379 C22orf25
chromosome 22 open reading frame 25
chr22_+_29808845 0.379 SMTN
smoothelin
chr15_+_65904994 0.378 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr1_+_28717234 0.377 NM_001048194
NM_001048195
NM_001269
RCC1


regulator of chromosome condensation 1


chr12_-_119123276 0.377 RPLP0P6
RPLP0
ribosomal protein, large, P0 pseudogene 6
ribosomal protein, large, P0
chr19_+_43585644 0.377 FAM98C
family with sequence similarity 98, member C
chr19_+_4742727 0.376 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr9_-_138742420 0.374 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chr22_-_17512174 0.373 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr1_-_17638729 0.372 RCC2
regulator of chromosome condensation 2
chr11_-_788196 0.370 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_33669190 0.367 PHC2
polyhomeotic homolog 2 (Drosophila)
chr10_-_15801661 0.366 NM_003638
ITGA8
integrin, alpha 8
chrX_+_77052879 0.364 ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr19_+_41237597 0.363 NM_001083961
NM_173636
WDR62

WD repeat domain 62

chr4_-_1980756 0.356 NM_005663
WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr11_+_61276576 0.354 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr1_-_1614040 0.353 NM_001110781
SLC35E2B
solute carrier family 35, member E2B
chr19_-_18912899 0.352 HOMER3
homer homolog 3 (Drosophila)
chr4_-_164473107 0.352 NM_000909
NPY1R
neuropeptide Y receptor Y1
chr3_-_185218311 0.349 NM_001023587
NM_005688
ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr6_-_110786167 0.349 NM_001123364
C6orf186
chromosome 6 open reading frame 186
chr2_+_182464713 0.348 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr19_+_4742757 0.348 FEM1A
fem-1 homolog a (C. elegans)
chr1_-_6684426 0.347 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr8_-_145521108 0.346 DGAT1
diacylglycerol O-acyltransferase 1
chr3_+_50167424 0.341 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_-_18913032 0.341 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr5_+_69732561 0.339 SMA4
glucuronidase, beta pseudogene
chr7_-_27149750 0.339 NM_019102
HOXA5
homeobox A5
chr22_-_21231421 0.339 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr12_-_119123292 0.337 RPLP0
ribosomal protein, large, P0
chr17_-_40565207 0.337 NM_133373
PLCD3
phospholipase C, delta 3
chr8_-_145605540 0.336 NM_013291
CPSF1
cleavage and polyadenylation specific factor 1, 160kDa
chr19_-_10807866 0.336 NM_006858
TMED1
transmembrane emp24 protein transport domain containing 1
chr22_-_19122047 0.334 SCARF2
scavenger receptor class F, member 2
chr1_-_200396354 0.333 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr11_-_64641700 0.333 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr16_+_65870891 0.332 NM_001129729
NM_001129731
PLEKHG4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

chr3_-_38046034 0.332 NM_006225
PLCD1
phospholipase C, delta 1
chr11_+_66790724 0.329 ADRBK1
adrenergic, beta, receptor kinase 1
chr1_+_152511708 0.327 HAX1
HCLS1 associated protein X-1
chr1_+_108765634 0.325 LOC400768
hypothetical LOC400768
chr1_-_170679833 0.325 NM_002642
NM_153747
PIGC

phosphatidylinositol glycan anchor biosynthesis, class C

chr3_-_129852400 0.324 NM_002950
RPN1
ribophorin I
chr6_+_35418295 0.324 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr22_-_29833484 0.321 NM_080430
SELM
selenoprotein M
chr17_-_30493382 0.320 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr1_-_33110668 0.319 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr1_-_113051200 0.319 NM_001042679
RHOC
ras homolog gene family, member C
chr11_-_130291584 0.317 NM_014758
SNX19
sorting nexin 19
chr1_-_170679794 0.316 PIGC
phosphatidylinositol glycan anchor biosynthesis, class C
chr12_-_119187932 0.315 NM_001080855
NM_002859
PXN

paxillin


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 1.27e-04 GO:0005622 intracellular
1.13 2.87e-03 GO:0044424 intracellular part
1.18 3.54e-03 GO:0005737 cytoplasm
1.24 4.49e-03 GO:0044444 cytoplasmic part
1.47 5.49e-03 GO:0005829 cytosol
4.12 4.30e-02 GO:0015934 large ribosomal subunit

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 1.15e-03 GO:0005515 protein binding