Motif ID: TFAP2B.p2

Z-value: 0.805


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP2Bchr6_+_50894397-0.165.6e-01Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_39664706 1.730 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr10_-_99175685 1.077


chr17_-_24940728 0.917 NM_001085454
NM_014030
GIT1

G protein-coupled receptor kinase interacting ArfGAP 1

chr17_-_24940521 0.849 GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr10_+_134060681 0.735 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr17_-_24940746 0.713 GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr19_-_1518875 0.694 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr9_+_123501186 0.677 DAB2IP
DAB2 interacting protein
chrX_+_9943793 0.647 NM_015691
WWC3
WWC family member 3
chr22_+_48951286 0.641 NM_001160300
NM_052839
PANX2

pannexin 2

chr5_-_176833197 0.619 DBN1
drebrin 1
chr2_+_241023908 0.599 GPC1
glypican 1
chr9_+_136358145 0.581 RXRA
retinoid X receptor, alpha
chr5_-_176833259 0.573 NM_004395
DBN1
drebrin 1
chr9_+_131974506 0.571 NM_014286
NCS1
neuronal calcium sensor 1
chr9_+_137511448 0.555 NM_014811
KIAA0649
KIAA0649
chr5_-_2804768 0.555 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr9_+_136358134 0.550 NM_002957
RXRA
retinoid X receptor, alpha
chr1_+_22909916 0.546 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr9_+_95378492 0.515 NM_005392
PHF2
PHD finger protein 2
chr22_-_48607449 0.515 BRD1
bromodomain containing 1
chr19_+_12966970 0.510 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_1274618 0.510 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr20_+_61842063 0.489 SLC2A4RG
SLC2A4 regulator
chr19_-_1543691 0.488 MBD3
methyl-CpG binding domain protein 3
chr4_-_2233504 0.488 NM_006454
MXD4
MAX dimerization protein 4
chr6_+_1335067 0.486 NM_001452
FOXF2
forkhead box F2
chr14_-_22596522 0.475 NM_022478
NM_144985
CDH24

cadherin 24, type 2

chr7_-_139987044 0.472 DENND2A
DENN/MADD domain containing 2A
chr1_+_19843261 0.463 NM_005380
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr13_+_113546943 0.460 GAS6
growth arrest-specific 6
chr14_-_102045849 0.460 NM_152326
ANKRD9
ankyrin repeat domain 9
chr10_+_104394185 0.455 NM_030912
TRIM8
tripartite motif containing 8
chr2_-_127580975 0.452 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
BIN1









bridging integrator 1









chr16_-_79395379 0.452 NM_152342
CDYL2
chromodomain protein, Y-like 2
chr14_-_90352513 0.448 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chr14_-_102045749 0.447 ANKRD9
ankyrin repeat domain 9
chr22_+_36286350 0.442 NM_152243
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr7_-_74705276 0.438 NM_001145064
GATSL2
GATS protein-like 2
chr7_-_50828608 0.432 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr19_-_4016467 0.427 ZBTB7A
zinc finger and BTB domain containing 7A
chr1_-_1274160 0.424 NM_004421
DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr10_+_99463468 0.423 MARVELD1
MARVEL domain containing 1
chr7_+_1536847 0.413 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr13_-_109236897 0.406 NM_003749
IRS2
insulin receptor substrate 2
chr9_-_139060285 0.401 NPDC1
neural proliferation, differentiation and control, 1
chr7_+_150442652 0.397 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_+_7834124 0.392 EVI5L
ecotropic viral integration site 5-like
chr1_-_1233109 0.386 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr4_+_3264509 0.385 RGS12
regulator of G-protein signaling 12
chr15_+_97009194 0.383 IGF1R
insulin-like growth factor 1 receptor
chr3_-_130517759 0.381 NM_006026
H1FX
H1 histone family, member X
chr12_-_1573591 0.379 NM_152441
FBXL14
F-box and leucine-rich repeat protein 14
chr8_+_37672427 0.377 NM_025069
ZNF703
zinc finger protein 703
chr4_-_1232882 0.376 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chr1_+_9275542 0.372 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr11_-_525532 0.371 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr1_-_22136263 0.370 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr20_-_60375695 0.368 NM_005560
LAMA5
laminin, alpha 5
chr7_+_3307445 0.367 NM_152744
SDK1
sidekick homolog 1, cell adhesion molecule (chicken)
chr4_-_1232742 0.366 CTBP1
C-terminal binding protein 1
chr16_+_88517187 0.366 NM_006086
TUBB3
tubulin, beta 3
chr3_-_187025501 0.364 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr14_+_101899104 0.359 TECPR2
tectonin beta-propeller repeat containing 2
chr1_-_31154023 0.357 NM_014654
SDC3
syndecan 3
chr2_-_1727247 0.356 PXDN
peroxidasin homolog (Drosophila)
chr22_-_48607199 0.356 BRD1
bromodomain containing 1
chr17_-_53387493 0.356 CUEDC1
CUE domain containing 1
chr2_-_1727220 0.355 PXDN
peroxidasin homolog (Drosophila)
chr2_-_73193419 0.354 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr14_-_104333060 0.351 AKT1
v-akt murine thymoma viral oncogene homolog 1
chr16_-_3870121 0.351 NM_001079846
NM_004380
CREBBP

CREB binding protein

chr19_-_614155 0.350 RNF126
ring finger protein 126
chr16_-_4106186 0.350 NM_001116
ADCY9
adenylate cyclase 9
chr9_+_139633264 0.346 NM_001145527
NM_024757
EHMT1

euchromatic histone-lysine N-methyltransferase 1

chr19_-_614158 0.345 RNF126
ring finger protein 126
chr4_-_957269 0.344 DGKQ
diacylglycerol kinase, theta 110kDa
chr19_+_3958690 0.341 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr1_-_95165089 0.340 NM_001839
CNN3
calponin 3, acidic
chr13_+_113546912 0.339 GAS6
growth arrest-specific 6
chr17_+_56831951 0.339 NM_005994
TBX2
T-box 2
chr1_-_33669190 0.338 PHC2
polyhomeotic homolog 2 (Drosophila)
chr19_-_36531958 0.338 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr12_-_119187871 0.338 PXN
paxillin
chr12_-_108802561 0.335 NM_016433
GLTP
glycolipid transfer protein
chr14_-_90352395 0.334


chr14_+_74964261 0.333 NM_001135047
JDP2
Jun dimerization protein 2
chr18_-_72663193 0.332 LOC100131655
hypothetical LOC100131655
chr19_-_614219 0.330 NM_194460
RNF126
ring finger protein 126
chr11_+_12355600 0.330 NM_018222
PARVA
parvin, alpha
chr13_+_97593469 0.329 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr5_+_14196287 0.329 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr9_-_38059207 0.327 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr17_-_75624048 0.326 NM_019020
TBC1D16
TBC1 domain family, member 16
chr2_+_241023703 0.326 NM_002081
GPC1
glypican 1
chr19_+_40213431 0.326 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr13_+_109757593 0.326 NM_001846
COL4A2
collagen, type IV, alpha 2
chr19_-_614195 0.325 RNF126
ring finger protein 126
chr18_+_54681657 0.325 ZNF532
zinc finger protein 532
chr4_-_177950658 0.324 NM_005429
VEGFC
vascular endothelial growth factor C
chr17_+_56832492 0.322 TBX2
T-box 2
chr12_+_130878870 0.322 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr13_-_98536640 0.321 NM_001130049
NM_015296
DOCK9

dedicator of cytokinesis 9

chr5_-_178705036 0.317 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr14_-_104333123 0.317 NM_001014431
NM_001014432
AKT1

v-akt murine thymoma viral oncogene homolog 1

chr13_-_109757442 0.315 NM_001845
COL4A1
collagen, type IV, alpha 1
chr4_-_7991992 0.315 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr17_-_75808680 0.314 NM_000199
SGSH
N-sulfoglucosamine sulfohydrolase
chr22_-_41446740 0.313 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chr16_+_2016807 0.313 NM_001130012
NM_004785
SLC9A3R2

solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

chr5_-_178704934 0.313 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr9_-_38059082 0.313 SHB
Src homology 2 domain containing adaptor protein B
chr19_-_1543633 0.312 NM_003926
MBD3
methyl-CpG binding domain protein 3
chr4_-_2233606 0.312 MXD4
MAX dimerization protein 4
chr5_+_53849396 0.312 SNX18
sorting nexin 18
chr8_+_32525269 0.311 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr1_-_200380321 0.310 ARL8A
ADP-ribosylation factor-like 8A
chr22_+_44277354 0.309 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr7_-_100262971 0.308 NM_004444
EPHB4
EPH receptor B4
chr19_+_38376980 0.307 LRP3
low density lipoprotein receptor-related protein 3
chr2_-_235070431 0.306 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr3_-_195835298 0.306 NM_001011655
NM_001166305
NM_001166306
NM_138399
TMEM44



transmembrane protein 44



chr2_-_73193566 0.305 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr13_+_113546897 0.304 GAS6
growth arrest-specific 6
chr20_-_61676003 0.304 NM_001037335
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr19_-_50987487 0.303 DMWD
dystrophia myotonica, WD repeat containing
chr12_+_127317900 0.303 NM_001136103
TMEM132C
transmembrane protein 132C
chr15_-_68933481 0.303 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr20_+_59260847 0.302 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr22_-_49042065 0.300 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr7_+_44754700 0.300 ZMIZ2
zinc finger, MIZ-type containing 2
chr10_+_123912930 0.300 TACC2
transforming, acidic coiled-coil containing protein 2
chr22_+_38075703 0.300 NM_004711
NM_145731
SYNGR1

synaptogyrin 1

chr17_+_56832255 0.299 TBX2
T-box 2
chr12_-_105165805 0.298 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr17_+_78630793 0.298 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr1_+_2149993 0.297 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr7_-_50828159 0.297 GRB10
growth factor receptor-bound protein 10
chr14_-_104706159 0.296 NM_002226
NM_145159
JAG2

jagged 2

chr21_+_45649719 0.296


chr8_+_25097983 0.295 DOCK5
dedicator of cytokinesis 5
chr19_-_50987625 0.295 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr3_-_129024665 0.293 NM_001003794
MGLL
monoglyceride lipase
chr6_+_83130673 0.293 NM_001166392
TPBG
trophoblast glycoprotein
chr19_+_2187815 0.292 NM_007165
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr9_-_112840064 0.292 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr1_+_199884152 0.291 NAV1
neuron navigator 1
chr2_+_220015016 0.290 SPEG
SPEG complex locus
chr19_-_1814425 0.289 KLF16
Kruppel-like factor 16
chr13_+_97593411 0.288 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr17_+_75808685 0.288 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr14_-_104705753 0.287 JAG2
jagged 2
chr16_+_1299361 0.287 NM_194260
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr2_-_239987629 0.286 HDAC4
histone deacetylase 4
chr12_+_50271283 0.285 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr7_-_150960086 0.285 NM_024429
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_+_3045528 0.283 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr11_+_65802221 0.283 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr16_+_3010311 0.282 NM_016639
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr17_+_18069593 0.282 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr17_-_24068759 0.281 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr9_+_137119334 0.279 OLFM1
olfactomedin 1
chr16_-_56393871 0.279 KIFC3
kinesin family member C3
chr3_-_195835593 0.277 TMEM44
transmembrane protein 44
chr17_-_829655 0.275 NM_022463
NXN
nucleoredoxin
chr22_+_18499354 0.275 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr5_+_10617431 0.274 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr17_+_24944605 0.273 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr12_+_120944174 0.273 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr4_+_1232942 0.272 C4orf42
chromosome 4 open reading frame 42
chr20_+_4077409 0.272 NM_175839
NM_175840
NM_175841
NM_175842
SMOX



spermine oxidase



chr7_-_150495799 0.271 NM_001098834
GBX1
gastrulation brain homeobox 1
chr1_-_22342001 0.271 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr5_+_72452131 0.270 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr9_+_136673534 0.270 COL5A1
collagen, type V, alpha 1
chr1_+_64012154 0.269 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr16_-_3870714 0.269 CREBBP
CREB binding protein
chr10_-_725522 0.269 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr6_+_148705646 0.268 SASH1
SAM and SH3 domain containing 1
chr4_-_5945596 0.268 NM_001014809
CRMP1
collapsin response mediator protein 1
chr10_+_133850325 0.268 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr1_+_199884072 0.267 NM_020443
NAV1
neuron navigator 1
chr6_-_117193505 0.266 NM_001085480
FAM162B
family with sequence similarity 162, member B
chr14_-_100104014 0.266 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr12_+_26003218 0.266 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr19_-_15304307 0.264 BRD4
bromodomain containing 4
chr11_+_65443303 0.264 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr10_+_123913094 0.262 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr7_-_5427367 0.261


chr19_+_38377329 0.261 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr1_+_156229934 0.260 KIRREL
kin of IRRE like (Drosophila)
chr22_-_32646325 0.259 NM_004737
NM_133642
LARGE

like-glycosyltransferase

chr19_-_18913017 0.259 HOMER3
homer homolog 3 (Drosophila)
chr14_+_101899051 0.259 NM_001172631
NM_014844
TECPR2

tectonin beta-propeller repeat containing 2

chr12_+_95112385 0.259 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr16_+_387176 0.258 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr1_+_15883403 0.258 NM_015164
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr22_-_49041786 0.258 MAPK12
mitogen-activated protein kinase 12
chr10_-_131652007 0.258 NM_001005463
EBF3
early B-cell factor 3
chr9_-_129370954 0.258 FAM129B
family with sequence similarity 129, member B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 1.11e-19 GO:0009987 cellular process
1.14 4.33e-16 GO:0044237 cellular metabolic process
1.18 1.36e-15 GO:0044260 cellular macromolecule metabolic process
1.12 3.67e-13 GO:0050794 regulation of cellular process
1.31 1.80e-12 GO:0009653 anatomical structure morphogenesis
1.25 8.26e-12 GO:0048523 negative regulation of cellular process
1.15 1.14e-11 GO:0043170 macromolecule metabolic process
1.11 1.35e-11 GO:0008152 metabolic process
1.11 1.56e-11 GO:0050789 regulation of biological process
1.26 1.50e-10 GO:0006464 protein modification process
1.10 1.53e-10 GO:0065007 biological regulation
1.11 5.85e-10 GO:0044238 primary metabolic process
1.22 7.30e-10 GO:0048519 negative regulation of biological process
1.28 1.23e-09 GO:0007399 nervous system development
1.24 1.53e-09 GO:0043412 macromolecule modification
1.16 1.56e-09 GO:0032502 developmental process
1.21 1.63e-09 GO:0044267 cellular protein metabolic process
1.49 1.79e-09 GO:0000904 cell morphogenesis involved in differentiation
1.26 3.97e-09 GO:0023051 regulation of signaling
1.43 4.65e-09 GO:0032989 cellular component morphogenesis
1.28 6.15e-09 GO:0009966 regulation of signal transduction
1.43 1.59e-08 GO:0000902 cell morphogenesis
1.17 2.39e-08 GO:0048856 anatomical structure development
1.34 2.55e-08 GO:0048468 cell development
1.16 2.60e-08 GO:0016043 cellular component organization
1.46 3.30e-08 GO:0032990 cell part morphogenesis
1.46 4.23e-08 GO:0048858 cell projection morphogenesis
1.21 6.56e-08 GO:0048869 cellular developmental process
1.16 9.81e-08 GO:0007275 multicellular organismal development
1.15 1.03e-07 GO:0031323 regulation of cellular metabolic process
1.21 1.34e-07 GO:0030154 cell differentiation
1.39 1.86e-07 GO:0030030 cell projection organization
1.15 3.48e-07 GO:0080090 regulation of primary metabolic process
1.46 3.71e-07 GO:0048812 neuron projection morphogenesis
1.33 3.81e-07 GO:0048699 generation of neurons
1.32 3.89e-07 GO:0022008 neurogenesis
1.47 4.10e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.17 4.48e-07 GO:0048731 system development
1.47 4.98e-07 GO:0007409 axonogenesis
1.14 5.12e-07 GO:0019222 regulation of metabolic process
1.15 5.68e-07 GO:0060255 regulation of macromolecule metabolic process
1.15 6.16e-07 GO:0071840 cellular component organization or biogenesis
1.43 1.31e-06 GO:0031175 neuron projection development
1.16 1.79e-06 GO:0019538 protein metabolic process
1.17 2.54e-06 GO:0071842 cellular component organization at cellular level
1.39 2.72e-06 GO:0048666 neuron development
1.33 3.63e-06 GO:0016192 vesicle-mediated transport
1.16 1.78e-05 GO:0010468 regulation of gene expression
1.45 2.05e-05 GO:0007264 small GTPase mediated signal transduction
1.16 2.35e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.32 4.63e-05 GO:0030182 neuron differentiation
1.23 5.09e-05 GO:0035556 intracellular signal transduction
1.37 5.95e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 7.73e-05 GO:0009892 negative regulation of metabolic process
1.16 1.06e-04 GO:0048522 positive regulation of cellular process
1.46 1.21e-04 GO:0007411 axon guidance
1.32 1.36e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.27 1.66e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.16 2.03e-04 GO:0051252 regulation of RNA metabolic process
1.15 3.58e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.26 4.13e-04 GO:0031324 negative regulation of cellular metabolic process
1.12 4.47e-04 GO:0051179 localization
1.13 5.07e-04 GO:0051234 establishment of localization
1.14 5.16e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 5.19e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 6.75e-04 GO:0006793 phosphorus metabolic process
1.24 6.75e-04 GO:0006796 phosphate metabolic process
1.26 7.54e-04 GO:0006351 transcription, DNA-dependent
1.29 9.99e-04 GO:0045595 regulation of cell differentiation
1.40 1.02e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.28 1.15e-03 GO:0006468 protein phosphorylation
1.31 1.15e-03 GO:0010629 negative regulation of gene expression
1.14 1.36e-03 GO:0031326 regulation of cellular biosynthetic process
1.14 1.62e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.26 1.69e-03 GO:0051128 regulation of cellular component organization
1.35 1.81e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.14 2.15e-03 GO:0048518 positive regulation of biological process
1.24 2.24e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.13 2.31e-03 GO:0006810 transport
1.34 2.34e-03 GO:0072358 cardiovascular system development
1.34 2.34e-03 GO:0072359 circulatory system development
1.13 2.47e-03 GO:0009889 regulation of biosynthetic process
1.20 2.51e-03 GO:0051641 cellular localization
1.22 2.53e-03 GO:0051649 establishment of localization in cell
1.30 3.20e-03 GO:0009887 organ morphogenesis
1.28 3.51e-03 GO:0009790 embryo development
1.38 3.60e-03 GO:0048598 embryonic morphogenesis
1.14 3.83e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.21 4.28e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.41 4.47e-03 GO:0060284 regulation of cell development
1.15 4.55e-03 GO:0006355 regulation of transcription, DNA-dependent
1.31 5.77e-03 GO:0051253 negative regulation of RNA metabolic process
1.20 6.57e-03 GO:0031325 positive regulation of cellular metabolic process
1.23 7.04e-03 GO:0050793 regulation of developmental process
1.62 7.81e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.22 9.14e-03 GO:0032268 regulation of cellular protein metabolic process
1.27 9.25e-03 GO:0051254 positive regulation of RNA metabolic process
1.30 9.90e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.27 1.03e-02 GO:0009890 negative regulation of biosynthetic process
1.13 1.18e-02 GO:0044249 cellular biosynthetic process
1.75 1.19e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.46 1.20e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.10 1.28e-02 GO:0023052 signaling
1.11 1.35e-02 GO:0007165 signal transduction
1.22 1.37e-02 GO:0032774 RNA biosynthetic process
1.24 1.44e-02 GO:0046907 intracellular transport
1.26 1.54e-02 GO:0010628 positive regulation of gene expression
1.20 1.59e-02 GO:0044248 cellular catabolic process
1.26 1.62e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.15 1.69e-02 GO:0048583 regulation of response to stimulus
1.16 2.48e-02 GO:0016070 RNA metabolic process
1.16 2.58e-02 GO:0009059 macromolecule biosynthetic process
1.27 2.65e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.11 2.69e-02 GO:0034641 cellular nitrogen compound metabolic process
1.18 2.92e-02 GO:0009893 positive regulation of metabolic process
1.13 2.96e-02 GO:0009058 biosynthetic process
1.20 3.57e-02 GO:0051246 regulation of protein metabolic process
1.16 3.86e-02 GO:0034645 cellular macromolecule biosynthetic process
1.34 4.04e-02 GO:0009792 embryo development ending in birth or egg hatching
1.26 4.17e-02 GO:0009057 macromolecule catabolic process
1.39 4.32e-02 GO:0032446 protein modification by small protein conjugation
1.11 4.33e-02 GO:0006807 nitrogen compound metabolic process
1.44 4.36e-02 GO:0045786 negative regulation of cell cycle
1.26 4.57e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 4.84e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 4.84e-02 GO:0090304 nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 1.32e-39 GO:0005622 intracellular
1.11 1.62e-36 GO:0044424 intracellular part
1.14 2.65e-30 GO:0005737 cytoplasm
1.12 7.00e-22 GO:0043227 membrane-bounded organelle
1.10 1.13e-21 GO:0043226 organelle
1.12 1.37e-21 GO:0043231 intracellular membrane-bounded organelle
1.10 1.44e-21 GO:0043229 intracellular organelle
1.14 4.02e-16 GO:0044444 cytoplasmic part
1.14 1.99e-13 GO:0005634 nucleus
1.12 5.59e-10 GO:0044422 organelle part
1.03 7.13e-10 GO:0044464 cell part
1.12 7.47e-10 GO:0044446 intracellular organelle part
1.03 7.94e-10 GO:0005623 cell
1.21 9.69e-09 GO:0005829 cytosol
1.18 9.18e-07 GO:0031090 organelle membrane
1.34 9.23e-06 GO:0044431 Golgi apparatus part
1.25 2.84e-05 GO:0005794 Golgi apparatus
1.34 2.17e-04 GO:0000139 Golgi membrane
1.18 2.97e-04 GO:0012505 endomembrane system
1.53 7.61e-04 GO:0031252 cell leading edge
1.14 1.20e-03 GO:0044428 nuclear part
1.28 1.26e-03 GO:0030054 cell junction
1.55 2.26e-03 GO:0005912 adherens junction
1.18 3.62e-03 GO:0005654 nucleoplasm
1.15 5.66e-03 GO:0031981 nuclear lumen
1.49 7.79e-03 GO:0070161 anchoring junction
1.13 8.97e-03 GO:0070013 intracellular organelle lumen
1.12 1.31e-02 GO:0043233 organelle lumen
1.12 1.71e-02 GO:0031974 membrane-enclosed lumen
1.58 1.88e-02 GO:0030055 cell-substrate junction
1.61 2.13e-02 GO:0005925 focal adhesion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.31e-22 GO:0005515 protein binding
1.07 1.06e-17 GO:0005488 binding
1.51 6.52e-05 GO:0016791 phosphatase activity
1.09 3.83e-04 GO:0003824 catalytic activity
1.23 4.35e-04 GO:0001071 nucleic acid binding transcription factor activity
1.23 4.35e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 4.67e-04 GO:0004721 phosphoprotein phosphatase activity
1.26 6.12e-04 GO:0016301 kinase activity
1.24 8.62e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.33 1.10e-03 GO:0030695 GTPase regulator activity
1.16 1.40e-03 GO:0016740 transferase activity
1.22 1.54e-03 GO:0030528 transcription regulator activity
1.32 2.39e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.29 2.73e-03 GO:0008092 cytoskeletal protein binding
1.25 3.62e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.27 3.68e-03 GO:0004672 protein kinase activity
1.34 4.56e-03 GO:0008047 enzyme activator activity
1.13 4.59e-03 GO:0000166 nucleotide binding
1.31 7.18e-03 GO:0019904 protein domain specific binding
1.21 9.18e-03 GO:0030234 enzyme regulator activity
1.10 1.04e-02 GO:0003676 nucleic acid binding
1.51 1.05e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.29 3.23e-02 GO:0004674 protein serine/threonine kinase activity
1.12 3.52e-02 GO:0003677 DNA binding
1.36 4.58e-02 GO:0016881 acid-amino acid ligase activity