Motif ID: PAX8.p2

Z-value: 0.182


Transcription factors associated with PAX8.p2:

Gene SymbolEntrez IDGene Name
PAX8 7849 paired box 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX8chr2_-_1137529570.087.8e-01Click!


Activity profile for motif PAX8.p2.

activity profile for motif PAX8.p2


Sorted Z-values histogram for motif PAX8.p2

Sorted Z-values for motif PAX8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX8.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91346054 0.115 NM_001025232
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr8_+_39911630 0.095 NM_194294
IDO2
indoleamine 2,3-dioxygenase 2
chr1_+_246703249 0.078 NM_001005495
OR2T3
olfactory receptor, family 2, subfamily T, member 3
chr6_-_31215089 0.062 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr1_-_27825178 0.061 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_-_44464722 0.053


chr7_+_129771865 0.048 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr2_-_179380301 0.044 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr1_+_556968 0.041


chr10_+_85923473 0.040 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr4_+_75449720 0.036 NM_001432
EREG
epiregulin
chr2_+_79106333 0.035 NM_001008387
NM_198448
REG3G

regenerating islet-derived 3 gamma

chr11_+_4466684 0.026 NM_001005171
OR52K1
olfactory receptor, family 52, subfamily K, member 1
chr7_+_156128431 0.024 NM_001184997
RNF32
ring finger protein 32
chr12_-_101115677 0.024 NM_002674
PMCH
pro-melanin-concentrating hormone
chr7_-_99604171 0.023 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr1_-_246804680 0.022 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr7_+_110518297 0.021 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr2_-_87102453 0.020 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr12_-_101396459 0.019 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_-_64568641 0.019 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr17_+_9686572 0.018 GLP2R
glucagon-like peptide 2 receptor
chr7_+_149842850 0.014 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr1_+_150997129 0.014 NM_001025231
KPRP
keratinocyte proline-rich protein
chr3_+_11153778 0.011 NM_001098213
HRH1
histamine receptor H1
chrX_-_33139349 0.008 NM_004006
DMD
dystrophin
chr1_+_152566899 0.007 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr1_+_66570683 0.006 PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_+_129057152 0.006 NM_001040110
NRF1
nuclear respiratory factor 1
chr17_-_23721485 0.005 NM_000638
VTN
vitronectin
chr1_-_47179729 0.004 NM_000778
CYP4A11
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 11
cytochrome P450, family 4, subfamily A, polypeptide 22
chr9_-_4656665 0.004 NM_001039395
C9orf68
chromosome 9 open reading frame 68
chr13_-_102209422 0.003 NM_001146197
C13orf40
chromosome 13 open reading frame 40
chr10_+_135190855 0.003 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr5_-_94250357 0.002 MCTP1
multiple C2 domains, transmembrane 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.73 1.94e-02 GO:0005626 insoluble fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
266.05 1.02e-03 GO:0018685 alkane 1-monooxygenase activity
17.33 3.54e-03 GO:0020037 heme binding
152.04 3.56e-03 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
16.28 4.52e-03 GO:0046906 tetrapyrrole binding
19.74 2.19e-02 GO:0004497 monooxygenase activity
10.26 2.66e-02 GO:0005506 iron ion binding