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Motif ID: HSF1,2.p2

Z-value: 1.103

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_44234525	1.710	NM_007058	CAPN11	calpain 11
chr12_+_118100977	1.552	NM_014365	HSPB8	heat shock 22kDa protein 8
chr5_-_110090264	1.466	NM_001039763	TMEM232	transmembrane protein 232
chr3_-_36756355	1.453	NM_033403	DCLK3	doublecortin-like kinase 3
chr5_-_112798436	1.331	NM_032028	TSSK1B	testis-specific serine kinase 1B
chr11_+_12265022	1.288	NM_032867	MICALCL	MICAL C-terminal like
chr6_-_31890765	1.248	NM_005527	HSPA1L	heat shock 70kDa protein 1-like
chr9_-_90983501	1.230	NM_016848	SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr2_+_210152609	1.225	NM_002374 NM_031845 NM_031847	MAP2	microtubule-associated protein 2
chr1_+_12757570	1.200	NM_001080830	PRAMEF12	PRAME family member 12
chr19_+_40298571	1.180	NM_001136007 NM_001136008 NM_001136009 NM_001136010 NM_001136011 NM_001136012 NM_005971 NM_021910	FXYD3	FXYD domain containing ion transport regulator 3
chr14_-_21108714	1.157	NM_001005465	OR10G3	olfactory receptor, family 10, subfamily G, member 3
chr12_-_12994584	1.096	NM_018654	GPRC5D	G protein-coupled receptor, family C, group 5, member D
chr20_+_31334601	1.092	NM_033197	C20orf114	chromosome 20 open reading frame 114
chr11_+_68818175	1.077	NM_138768	MYEOV	myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr7_-_75876830	1.074	NM_080744	SRCRB4D	scavenger receptor cysteine rich domain containing, group B (4 domains)
chr6_+_54281161	1.036	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr22_+_22907443	1.035	NM_019601	SUSD2	sushi domain containing 2
chr6_+_29472310	1.006	NM_013936	OR12D2	olfactory receptor, family 12, subfamily D, member 2
chr2_-_113259441	0.990	NM_000575	IL1A	interleukin 1, alpha
chr11_-_104411065	0.984	NM_001223 NM_033292 NM_033293 NM_033294 NM_033295	CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr6_+_31891259	0.980	NM_005345	HSPA1A	heat shock 70kDa protein 1A
chr17_-_36890877	0.973	NM_002280	KRT35	keratin 35
chr9_+_108726257	0.959		ZNF462	zinc finger protein 462
chr7_-_27133163	0.953	NM_153631	HOXA3	homeobox A3
chr3_-_64648703	0.949		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_-_80386258	0.947		SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_111053488	0.942	NM_001178130 NM_001178131 NM_001963	EGF	epidermal growth factor
chr1_-_173979292	0.941	NM_003285	TNR	tenascin R (restrictin, janusin)
chr5_+_79366746	0.917	NM_003248	THBS4	thrombospondin 4
chr1_+_155052094	0.910	NM_001007792	NTRK1	neurotrophic tyrosine kinase, receptor, type 1
chr5_+_147423727	0.893	NM_001127698 NM_001127699 NM_006846	SPINK5	serine peptidase inhibitor, Kazal type 5
chr7_-_80386602	0.889	NM_006379	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_217268492	0.886	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr8_+_32698892	0.885	NM_001159996	NRG1	neuregulin 1
chr12_+_8557402	0.879	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr2_-_197383120	0.878	NM_213608	C2orf66	chromosome 2 open reading frame 66
chr12_-_14887648	0.870	NM_021071	ART4	ADP-ribosyltransferase 4 (Dombrock blood group)
chr12_+_47584159	0.864	NM_033124	CCDC65	coiled-coil domain containing 65
chr6_+_31891293	0.862		HSPA1A	heat shock 70kDa protein 1A
chr7_-_36730525	0.862	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chr6_+_31190505	0.849	NM_014068	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr5_-_41107161	0.830	NM_173489	HEATR7B2	HEAT repeat family member 7B2
chr20_+_55338221	0.823	NM_012444 NM_198265	SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
chr19_+_50693570	0.820	NM_001080401	PPM1N	protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr10_+_122206455	0.819	NM_001030059	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A
chr5_-_135318420	0.797	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr17_+_53670785	0.795	NM_001160102 NM_006151	LPO	lactoperoxidase
chr2_+_219532590	0.794	NM_003936	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr5_-_22248630	0.792		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr15_+_52092392	0.792	NM_001080534	UNC13C	unc-13 homolog C (C. elegans)
chr7_-_127042810	0.785	NM_006193	PAX4	paired box 4
chr2_+_161981138	0.779		TBR1	T-box, brain, 1
chr14_+_62740878	0.778	NM_020663	RHOJ	ras homolog gene family, member J
chr16_+_4546491	0.773	NM_001145011	LOC342346	hypothetical protein LOC342346
chr10_+_18280773	0.751	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr5_-_148422799	0.750	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr22_+_22907417	0.746		SUSD2	sushi domain containing 2
chr2_+_166137091	0.730	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr3_+_160269734	0.729	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr1_-_148175383	0.728	NM_001145862	MTMR11	myotubularin related protein 11
chr12_-_3472245	0.726		LOC100129223	hypothetical LOC100129223
chr12_+_120055013	0.725	NM_002562	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7
chr7_+_129807467	0.723	NM_001868	CPA1	carboxypeptidase A1 (pancreatic)
chr12_-_121753795	0.721	NM_177551	GPR109A	G protein-coupled receptor 109A
chr19_-_54258935	0.719	NM_006179	NTF4	neurotrophin 4
chr2_-_142605739	0.717	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr2_+_26768894	0.716	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr1_-_112333192	0.712	NM_004980 NM_172198	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_-_150353179	0.704	NM_007113	TCHH	trichohyalin
chr11_-_34491878	0.702	NM_001422	ELF5	E74-like factor 5 (ets domain transcription factor)
chr20_+_19818209	0.702	NM_018993	RIN2	Ras and Rab interactor 2
chr14_-_22458134	0.698		RBM23	RNA binding motif protein 23
chr2_+_234292162	0.698	NM_007120	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr6_+_31903374	0.694	NM_005346	HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr11_-_10671736	0.694		MRVI1	murine retrovirus integration site 1 homolog
chr3_-_9265592	0.691		SRGAP3	SLIT-ROBO Rho GTPase activating protein 3
chrX_+_152454773	0.688	NM_001001344 NM_021949	ATP2B3	ATPase, Ca++ transporting, plasma membrane 3
chr11_-_6298284	0.688	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr4_+_77575276	0.687	NM_020859	SHROOM3	shroom family member 3
chr6_+_46728590	0.683	NM_004277	SLC25A27	solute carrier family 25, member 27
chr8_-_37916803	0.683	NM_152413	GOT1L1	glutamic-oxaloacetic transaminase 1-like 1
chr20_-_61574259	0.680	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr1_+_47674275	0.679	NM_004474	FOXD2	forkhead box D2
chr18_+_27152049	0.677	NM_001942	DSG1	desmoglein 1
chr19_-_54252813	0.664		CGB7	chorionic gonadotropin, beta polypeptide 7
chr9_+_83748234	0.664	NM_207416	FAM75D3	family with sequence similarity 75, member D3
chr10_-_90601655	0.663	NM_144590	ANKRD22	ankyrin repeat domain 22
chr17_+_21249040	0.661	NM_001194958	KCNJ18	potassium inwardly-rectifying channel, subfamily J, member 18
chr19_-_60557875	0.660	NM_144613	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr10_+_135190855	0.657	NM_000773	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_-_153820535	0.655	NM_152680	TMEM154	transmembrane protein 154
chr2_-_189752575	0.655	NM_000393	COL5A2	collagen, type V, alpha 2
chr17_-_24068759	0.645	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chr11_-_35503720	0.637	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr1_-_200946038	0.636	NM_177402	SYT2	synaptotagmin II
chr6_+_32817140	0.629	NM_020056	HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2
chr16_+_54158084	0.623	NM_032330	CAPNS2	calpain, small subunit 2
chr1_+_109450116	0.620
chr9_-_89939719	0.614	NM_001166137	FAM75C2	family with sequence similarity 75, member C2
chr11_+_1812115	0.614	NM_138567	SYT8	synaptotagmin VIII
chr6_+_116939500	0.608	NM_153711	FAM26E	family with sequence similarity 26, member E
chr9_+_831689	0.606	NM_021951	DMRT1	doublesex and mab-3 related transcription factor 1
chr15_-_39973566	0.605	NM_016642	SPTBN5	spectrin, beta, non-erythrocytic 5
chr19_+_3073297	0.605		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr1_-_158190585	0.599	NM_001146172 NM_001146173 NM_033438	SLAMF9	SLAM family member 9
chr12_-_51253875	0.598	NM_175053	KRT74	keratin 74
chr3_-_48607596	0.598	NM_000094	COL7A1	collagen, type VII, alpha 1
chr19_-_53941835	0.597	NM_182575	IZUMO1	izumo sperm-egg fusion 1
chr2_+_202379442	0.596	NM_139158	CDK15	cyclin-dependent kinase 15
chr18_+_18003401	0.591	NM_005257	GATA6	GATA binding protein 6
chr16_-_73012740	0.590	NM_001011880	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr17_-_76897590	0.588	NM_178519	C17orf55	chromosome 17 open reading frame 55
chr7_-_83662152	0.586	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_21818881	0.584	NM_004982	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr11_-_47692877	0.581	NM_024783	AGBL2	ATP/GTP binding protein-like 2
chr2_-_39040981	0.580		LOC375196	hypothetical LOC375196
chr8_+_22078622	0.578		BMP1	bone morphogenetic protein 1
chr19_+_3073560	0.578
chr3_+_44665220	0.577	NM_003420	ZNF35	zinc finger protein 35
chr6_+_134800533	0.576		LOC154092	hypothetical LOC154092
chr2_+_220007943	0.573	NM_005876	SPEG	SPEG complex locus
chr2_+_210152399	0.572		MAP2	microtubule-associated protein 2
chr12_+_10054492	0.571	NM_001129998 NM_205852	CLEC12B	C-type lectin domain family 12, member B
chr1_-_148175345	0.566		MTMR11	myotubularin related protein 11
chr4_-_160175782	0.566	NM_152543	C4orf45	chromosome 4 open reading frame 45
chr11_-_121492010	0.563	NM_001001786	BLID	BH3-like motif containing, cell death inducer
chr12_-_121224676	0.563	NM_001014336	IL31	interleukin 31
chr5_-_146813343	0.563	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr6_+_152168500	0.562	NM_001122741	ESR1	estrogen receptor 1
chr14_-_22458199	0.561		RBM23	RNA binding motif protein 23
chr7_+_75769927	0.560		HSPB1	heat shock 27kDa protein 1
chr3_-_74652952	0.560	NM_020872	CNTN3	contactin 3 (plasmacytoma associated)
chr11_-_10671608	0.557	NM_001100167	MRVI1	murine retrovirus integration site 1 homolog
chr19_-_60383280	0.556	NM_003180	SYT5	synaptotagmin V
chr9_-_90983195	0.552		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr19_-_14750347	0.552	NM_013447 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921	EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr6_+_83129641	0.552	NM_006670	TPBG	trophoblast glycoprotein
chr17_-_71648965	0.550	NM_001454	FOXJ1	forkhead box J1
chr8_-_142307854	0.543	NM_001080431	SLC45A4	solute carrier family 45, member 4
chr4_-_123092358	0.541	NM_001130698	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr3_-_135131207	0.540	NM_025041	C3orf36	chromosome 3 open reading frame 36
chr2_-_169596078	0.538	NM_003742	ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr17_-_10217046	0.536	NM_003802	MYH13	myosin, heavy chain 13, skeletal muscle
chr12_-_83830710	0.535	NM_001146335 NM_018057 NM_182767	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr3_+_191588354	0.535	NM_006580	CLDN16	claudin 16
chr8_+_39890484	0.534	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr19_+_15079141	0.531	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr12_-_121767272	0.531	NM_006018	GPR109B	G protein-coupled receptor 109B
chr9_-_116732403	0.526	NM_001244	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8
chr11_+_89458765	0.525	NM_001143975	UBTFL1	upstream binding transcription factor, RNA polymerase I-like 1
chr3_+_1109619	0.525	NM_014461	CNTN6	contactin 6
chrX_-_10495476	0.523	NM_001193278 NM_001193279 NM_001193280 NM_001193281	MID1	midline 1 (Opitz/BBB syndrome)
chr9_-_72926333	0.522	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr3_-_184756101	0.522	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr3_+_98016114	0.520	NM_001080448	EPHA6	EPH receptor A6
chr11_+_64079665	0.518	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr2_+_113533155	0.518	NM_012275	IL1F5	interleukin 1 family, member 5 (delta)
chr19_-_14490227	0.516		DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_-_169392771	0.514
chr9_+_36159384	0.514	NM_005893	CCIN	calicin
chr7_-_4867963	0.513	NM_020144	PAPOLB	poly(A) polymerase beta (testis specific)
chr3_-_64186151	0.513	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr14_-_76564374	0.509		IRF2BPL	interferon regulatory factor 2 binding protein-like
chr17_+_7199178	0.509	NM_198154	TMEM95	transmembrane protein 95
chr12_-_51298599	0.509	NM_175068	KRT73	keratin 73
chrX_-_110542040	0.507	NM_178151 NM_001195553 NM_178152 NM_178153	DCX	doublecortin
chr6_+_47774247	0.506	NM_153838	GPR115	G protein-coupled receptor 115
chr8_-_26427304	0.505	NM_007257	PNMA2	paraneoplastic antigen MA2
chr18_-_26996742	0.503	NM_004948 NM_024421	DSC1	desmocollin 1
chr14_-_59407103	0.502	NM_021136	RTN1	reticulon 1
chr5_-_22889487	0.500	NM_004061	CDH12	cadherin 12, type 2 (N-cadherin 2)
chr6_-_117193505	0.500	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr8_-_23768242	0.498	NM_003155	STC1	stanniocalcin 1
chr22_+_30769018	0.496	NM_000343	SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr17_-_40348378	0.496	NM_001131019 NM_002055	GFAP	glial fibrillary acidic protein
chr11_-_27637771	0.496	NM_001143816 NM_170735	BDNF	brain-derived neurotrophic factor
chr6_+_159510416	0.494	NM_032532	FNDC1	fibronectin type III domain containing 1
chr12_+_6768966	0.491		CD4	CD4 molecule
chr2_+_234490781	0.489	NM_024080	TRPM8	transient receptor potential cation channel, subfamily M, member 8
chr1_-_150092702	0.489	NM_182578	THEM5	thioesterase superfamily member 5
chr5_+_140762551	0.488	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr19_+_56049982	0.488	NM_001030047 NM_001030048 NM_001030050 NM_001648	KLK3	kallikrein-related peptidase 3
chr3_-_59010777	0.482		C3orf67	chromosome 3 open reading frame 67
chr7_+_134114912	0.480		CALD1	caldesmon 1
chr5_-_83052606	0.479	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr5_+_139485703	0.477	NM_001007189	C5orf53	chromosome 5 open reading frame 53
chr4_+_71713324	0.477	NM_031889	ENAM	enamelin
chr14_+_28306633	0.474		FOXG1	forkhead box G1
chr16_+_29697090	0.472		ZG16	zymogen granule protein 16 homolog (rat)
chr11_-_133332089	0.471	NM_014987	IGSF9B	immunoglobulin superfamily, member 9B
chr9_+_34979674	0.468	NM_001135004 NM_012266	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_-_68821131	0.468	NM_020361	CPA6	carboxypeptidase A6
chr13_+_109932934	0.465		COL4A2	collagen, type IV, alpha 2
chr18_+_29573152	0.465		ASXL3	additional sex combs like 3 (Drosophila)
chr22_+_44828338	0.462
chr7_-_14847479	0.461	NM_004080 NM_145695	DGKB	diacylglycerol kinase, beta 90kDa
chr14_-_80934523	0.461	NM_033104	STON2	stonin 2
chr5_-_180560535	0.458	NM_203297	TRIM7	tripartite motif containing 7
chr11_+_123405506	0.457	NM_001004464	OR10G8	olfactory receptor, family 10, subfamily G, member 8

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.31	9.27e-15	GO:0032501	multicellular organismal process
1.32	2.36e-08	GO:0007275	multicellular organismal development
1.28	5.97e-07	GO:0032502	developmental process
1.34	1.03e-06	GO:0048731	system development
1.71	2.14e-06	GO:0007155	cell adhesion
1.71	2.14e-06	GO:0022610	biological adhesion
1.30	4.63e-06	GO:0048856	anatomical structure development
1.43	8.00e-06	GO:0003008	system process
1.44	3.54e-05	GO:0009653	anatomical structure morphogenesis
1.56	3.15e-04	GO:0040011	locomotion
1.87	4.16e-04	GO:0060429	epithelium development
1.70	4.95e-04	GO:0006928	cellular component movement
1.33	6.01e-04	GO:0030154	cell differentiation
1.54	8.16e-04	GO:0009888	tissue development
1.41	8.59e-04	GO:0050877	neurological system process
1.32	1.05e-03	GO:0048869	cellular developmental process
1.34	1.75e-03	GO:0048513	organ development
1.38	2.08e-03	GO:0007399	nervous system development
1.82	5.25e-03	GO:0007389	pattern specification process
1.73	5.37e-03	GO:0007608	sensory perception of smell
6.64	7.51e-03	GO:0060600	dichotomous subdivision of an epithelial terminal unit
1.49	8.98e-03	GO:0007600	sensory perception
2.87	9.37e-03	GO:0048762	mesenchymal cell differentiation
1.65	1.51e-02	GO:0007606	sensory perception of chemical stimulus
2.03	3.44e-02	GO:0030855	epithelial cell differentiation
1.48	4.45e-02	GO:2000026	regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.31	2.68e-11	GO:0005886	plasma membrane
1.30	3.64e-11	GO:0071944	cell periphery
1.67	5.19e-10	GO:0044421	extracellular region part
1.45	6.24e-10	GO:0005576	extracellular region
2.15	2.10e-09	GO:0031012	extracellular matrix
2.12	2.07e-07	GO:0005578	proteinaceous extracellular matrix
1.17	1.38e-05	GO:0044425	membrane part
1.18	3.03e-05	GO:0031224	intrinsic to membrane
1.17	1.50e-04	GO:0016021	integral to membrane
1.29	5.28e-04	GO:0044459	plasma membrane part
1.50	8.49e-04	GO:0005615	extracellular space
1.12	9.45e-04	GO:0016020	membrane
2.18	2.98e-02	GO:0044420	extracellular matrix part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.38	4.14e-05	GO:0004872	receptor activity
1.42	2.96e-04	GO:0004888	transmembrane receptor activity
1.31	3.28e-04	GO:0004871	signal transducer activity
1.31	3.28e-04	GO:0060089	molecular transducer activity
1.74	1.68e-03	GO:0004984	olfactory receptor activity
1.50	1.18e-02	GO:0005509	calcium ion binding
1.76	2.86e-02	GO:0005261	cation channel activity
1.41	3.18e-02	GO:0004930	G-protein coupled receptor activity
1.45	4.63e-02	GO:0043565	sequence-specific DNA binding