Motif ID: SPIB.p2

Z-value: 2.329


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_556140060.312.4e-01Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_44643067 2.713 ABI3
ABI family, member 3
chr18_-_51219880 2.548 TCF4
transcription factor 4
chr12_-_15005761 2.477 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_175207521 2.274 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr4_+_91035025 2.207 NM_007351
MMRN1
multimerin 1
chr6_-_32742265 1.662 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr18_-_59137488 1.632 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr21_-_38792173 1.630 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr9_+_263025 1.593 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr7_+_149778869 1.519 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr12_+_25096755 1.498 LRMP
lymphoid-restricted membrane protein
chr3_-_113701073 1.468 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr6_-_159386007 1.376 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr18_-_16945763 1.367 NM_005406
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr7_+_149778815 1.365 GIMAP8
GTPase, IMAP family member 8
chr17_+_64922420 1.359 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_174557191 1.343 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr10_-_64246129 1.281 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr2_-_225519974 1.274 DOCK10
dedicator of cytokinesis 10
chr19_+_14554895 1.252 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr2_-_197165495 1.216 NM_020760
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_-_101658094 1.172 NM_001159694
NM_016242
EMCN

endomucin

chr3_-_122862447 1.150 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_+_31661934 1.146 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chrX_-_44945025 1.139 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr14_+_87541220 1.124 NM_003608
GPR65
G protein-coupled receptor 65
chr12_+_25096472 1.123 NM_006152
LRMP
lymphoid-restricted membrane protein
chr7_+_149779011 1.119 GIMAP8
GTPase, IMAP family member 8
chrX_-_100527799 1.111 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr17_-_44642934 1.100 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_+_168996852 1.097 DOCK2
dedicator of cytokinesis 2
chr9_-_129580732 1.083 NM_170600
SH2D3C
SH2 domain containing 3C
chr7_+_150013716 1.069 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr10_+_26767288 1.058 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_+_106293112 1.047 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr11_+_59979857 1.042 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chrX_+_48427137 1.033 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr3_-_122862391 1.014 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_25473528 1.007 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_181826633 1.006 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr14_+_49157150 0.996 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_+_53177806 0.996 NCKAP1L
NCK-associated protein 1-like
chr10_+_12431477 0.990 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr18_-_59138192 0.988 BCL2
B-cell CLL/lymphoma 2
chr2_-_197883739 0.983 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chrX_+_48427103 0.978 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_-_101073632 0.960 NM_001011657
ZMAT1
zinc finger, matrin-type 1
chr3_+_120495906 0.948 NM_020754
ARHGAP31
Rho GTPase activating protein 31
chr1_+_159943385 0.947 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr1_-_181826086 0.941 NCF2
neutrophil cytosolic factor 2
chr12_+_4253143 0.933 NM_001759
CCND2
cyclin D2
chr18_-_16945613 0.923 ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr10_+_31647425 0.918 ZEB1
zinc finger E-box binding homeobox 1
chr2_-_197883569 0.917 ANKRD44
ankyrin repeat domain 44
chr7_-_37454933 0.902 NM_014800
ELMO1
engulfment and cell motility 1
chr12_+_53177789 0.892 NCKAP1L
NCK-associated protein 1-like
chr11_+_63864263 0.879 NM_032251
CCDC88B
coiled-coil domain containing 88B
chrX_-_74292800 0.865 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr10_-_53129315 0.863 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr12_+_53177758 0.863 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr16_+_28413421 0.861 NM_018690
APOBR
apolipoprotein B receptor
chr4_+_39874921 0.858 NM_004310
RHOH
ras homolog gene family, member H
chr1_+_100957883 0.855 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr10_+_70517823 0.851 NM_002727
SRGN
serglycin
chr17_+_44642587 0.849 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr9_+_119506274 0.848 NM_138554
TLR4
toll-like receptor 4
chr1_-_158759606 0.837 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr7_+_106292975 0.837 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_-_54317102 0.825 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr6_+_108593907 0.817 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr6_-_6265874 0.816 F13A1
coagulation factor XIII, A1 polypeptide
chr2_-_96174865 0.809 NM_004418
DUSP2
dual specificity phosphatase 2
chr8_+_69027143 0.804 NM_024870
NM_025170
PREX2

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

chr1_-_181826292 0.803 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr6_-_154719560 0.791 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_+_106292932 0.787 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_-_169657192 0.782 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr10_+_129735796 0.775 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr12_-_116890410 0.773 NM_173598
KSR2
kinase suppressor of ras 2
chrX_+_86659370 0.766 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr6_-_6265896 0.764 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr10_-_98470164 0.753 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr1_-_25128951 0.749 RUNX3
runt-related transcription factor 3
chr6_+_31651319 0.748 NM_000594
TNF
tumor necrosis factor
chr1_-_171441234 0.746 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr17_+_31664143 0.744 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_-_111848265 0.743 NM_000677
NM_020683
ADORA3

adenosine A3 receptor

chr11_+_113435640 0.741 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr8_-_99126942 0.741 NM_000989
RPL30
ribosomal protein L30
chr7_+_149895390 0.741 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr16_+_64958025 0.741 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chr6_-_33085329 0.741 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr6_+_130381408 0.735 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr17_+_73638430 0.731 NM_152468
TMC8
transmembrane channel-like 8
chr1_+_43410587 0.731 NM_001167965
NM_152498
NM_001167966
WDR65


WD repeat domain 65


chr11_-_64327197 0.723 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr3_+_133923758 0.717 NCRNA00119
non-protein coding RNA 119
chr8_-_92151363 0.716


chr7_-_4867963 0.713 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chrX_+_56772391 0.710 LOC550643
hypothetical LOC550643
chr12_+_79625538 0.701 NM_002469
MYF6
myogenic factor 6 (herculin)
chr2_+_102401580 0.697 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr5_-_169657312 0.696 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_7348194 0.691 NM_001080454
ACSM4
acyl-CoA synthetase medium-chain family member 4
chrX_-_20194831 0.690 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr9_+_4975243 0.690 NM_004972
JAK2
Janus kinase 2
chr11_+_101693403 0.689 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr1_+_182040837 0.685 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_27972269 0.684 NM_177424
STX12
syntaxin 12
chr1_-_144426918 0.680 NM_007053
CD160
CD160 molecule
chr10_+_70517863 0.676 SRGN
serglycin
chr6_-_25044156 0.667 FAM65B
family with sequence similarity 65, member B
chr5_-_169657395 0.666 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_-_213723298 0.664 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr22_+_29333069 0.662 NM_000355
NM_001184726
TCN2

transcobalamin II

chr1_-_23758503 0.658 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr17_+_69974361 0.655 CD300A
CD300a molecule
chr9_+_119506446 0.654 TLR4
toll-like receptor 4
chr1_+_101134276 0.653 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr2_+_157000197 0.651 NM_001083112
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr19_+_46774370 0.651 NM_001098506
NM_033543
CEACAM21

carcinoembryonic antigen-related cell adhesion molecule 21

chrX_-_103288263 0.650 NM_001012755
MCART6
mitochondrial carrier triple repeat 6
chr6_+_336738 0.648 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chr1_+_165865953 0.645 NM_052862
RCSD1
RCSD domain containing 1
chr3_-_123223658 0.642 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr6_-_33085290 0.642 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr8_-_6407882 0.641 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chrX_+_134482212 0.639 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr13_-_101852028 0.637 NM_175929
FGF14
fibroblast growth factor 14
chrX_+_134482387 0.635 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_-_92122219 0.635 NM_018710
TMEM55A
transmembrane protein 55A
chr3_+_180348818 0.630 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr8_-_108579270 0.629 NM_001146
ANGPT1
angiopoietin 1
chr10_-_27189898 0.628 ABI1
abl-interactor 1
chr14_+_64040979 0.619 NM_001123329
NM_014950
ZBTB1

zinc finger and BTB domain containing 1

chrX_+_15428820 0.616 NM_203281
BMX
BMX non-receptor tyrosine kinase
chrX_-_20195062 0.616 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_-_224974954 0.614 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr5_-_158459276 0.613 NM_024007
EBF1
early B-cell factor 1
chr7_-_98844211 0.609 NM_014891
PDAP1
PDGFA associated protein 1
chr15_+_68971835 0.607 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr16_+_29582065 0.606 SPN
sialophorin
chr1_-_23758871 0.605 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_+_48223183 0.598 NM_001004727
OR4X2
olfactory receptor, family 4, subfamily X, member 2
chr11_+_128067598 0.595 NM_001167681
FLI1
Friend leukemia virus integration 1
chr5_+_158622666 0.594 NM_145049
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr1_+_207995999 0.593 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr17_-_18890963 0.591 NM_006613
GRAP
GRB2-related adaptor protein
chr10_+_17891348 0.591 NM_001009567
NM_002438
MRC1L1
MRC1
mannose receptor, C type 1-like 1
mannose receptor, C type 1
chrX_+_74410618 0.588 NM_145052
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr17_-_59437782 0.587 NM_000873
ICAM2
intercellular adhesion molecule 2
chr15_+_49760841 0.584 NM_001165257
NM_013243
SCG3

secretogranin III

chr5_-_169657360 0.581 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_40337454 0.580 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_46438447 0.579 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr8_-_29263714 0.579 NM_001394
DUSP4
dual specificity phosphatase 4
chrX_-_111953009 0.578 NM_001113490
AMOT
angiomotin
chr2_+_157001072 0.576 NM_000408
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr19_+_54530458 0.576 CD37
CD37 molecule
chr17_+_29606408 0.576 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr10_-_64246080 0.574 EGR2
early growth response 2
chr7_+_87401368 0.573 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr2_-_197883703 0.572 ANKRD44
ankyrin repeat domain 44
chr1_-_31003181 0.570 LAPTM5
lysosomal protein transmembrane 5
chr1_+_111818111 0.570 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr5_-_156468614 0.566 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chr17_-_40843530 0.565 ARHGAP27
Rho GTPase activating protein 27
chr11_-_58736897 0.564 NM_001039396
MPEG1
macrophage expressed 1
chr10_+_70553993 0.559 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr2_+_68445821 0.557 NM_002664
PLEK
pleckstrin
chr8_+_105421226 0.556 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr7_+_27191534 0.556 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr5_-_138822475 0.555 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr13_-_45654327 0.555 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_+_37524250 0.554 CYBB
cytochrome b-245, beta polypeptide
chr3_+_16901455 0.553 NM_001144382
PLCL2
phospholipase C-like 2
chr17_+_7180571 0.553 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr10_+_26767268 0.552 NM_019043
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr14_+_64041170 0.550 ZBTB1
zinc finger and BTB domain containing 1
chr4_+_87070449 0.546 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr16_+_29581783 0.545 NM_001030288
SPN
sialophorin
chr4_-_35922288 0.543 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_5602782 0.540 NM_021616
TRIM34
tripartite motif containing 34
chr19_+_6723705 0.540 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr19_+_54530485 0.538 NM_001040031
NM_001774
CD37

CD37 molecule

chr8_-_114518194 0.532 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr5_-_139402989 0.532 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr7_+_23603495 0.531 NM_138771
CCDC126
coiled-coil domain containing 126
chr12_-_101398429 0.530 IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_-_107667728 0.530 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr6_+_12398514 0.530 NM_001168319
NM_001955
EDN1

endothelin 1

chr11_+_10787328 0.529


chr9_+_27099138 0.529 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr8_-_57149588 0.527 NM_001023
NM_001146227
RPS20

ribosomal protein S20

chr12_-_108918560 0.527 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr2_+_155263338 0.525 NM_002239
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_-_184756101 0.525 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_-_188021117 0.525 NM_005795
CALCRL
calcitonin receptor-like
chr4_+_156807311 0.523 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr17_+_9670105 0.519 NM_004246
GLP2R
glucagon-like peptide 2 receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 3.17e-10 GO:0002376 immune system process
1.10 5.74e-06 GO:0050794 regulation of cellular process
1.38 1.88e-05 GO:0006955 immune response
1.16 3.75e-05 GO:0007165 signal transduction
1.08 1.16e-04 GO:0065007 biological regulation
1.75 2.58e-04 GO:0051251 positive regulation of lymphocyte activation
1.69 7.00e-04 GO:0050867 positive regulation of cell activation
1.08 8.99e-04 GO:0050789 regulation of biological process
1.41 9.26e-04 GO:0044265 cellular macromolecule catabolic process
1.80 9.94e-04 GO:0050870 positive regulation of T cell activation
1.68 1.56e-03 GO:0002696 positive regulation of leukocyte activation
1.13 2.11e-03 GO:0023052 signaling
1.68 2.56e-03 GO:0050863 regulation of T cell activation
1.12 3.09e-03 GO:0051716 cellular response to stimulus
1.49 3.15e-03 GO:0070647 protein modification by small protein conjugation or removal
1.56 3.85e-03 GO:0050865 regulation of cell activation
2.13 4.55e-03 GO:0031294 lymphocyte costimulation
2.13 4.55e-03 GO:0031295 T cell costimulation
1.11 6.37e-03 GO:0044260 cellular macromolecule metabolic process
1.38 8.87e-03 GO:0007599 hemostasis
1.58 9.02e-03 GO:0051249 regulation of lymphocyte activation
1.38 9.27e-03 GO:0007596 blood coagulation
1.38 9.27e-03 GO:0050817 coagulation
1.53 1.57e-02 GO:0002694 regulation of leukocyte activation
1.67 1.57e-02 GO:0050900 leukocyte migration
1.33 1.78e-02 GO:0009057 macromolecule catabolic process
1.49 2.20e-02 GO:0032446 protein modification by small protein conjugation
1.84 2.63e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.30 2.86e-02 GO:0002682 regulation of immune system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.03 1.01e-06 GO:0044464 cell part
1.03 1.09e-06 GO:0005623 cell
1.11 6.52e-06 GO:0005634 nucleus
1.06 1.51e-03 GO:0043227 membrane-bounded organelle
1.06 1.70e-03 GO:0043231 intracellular membrane-bounded organelle
1.16 4.89e-03 GO:0044428 nuclear part
1.04 6.51e-03 GO:0005622 intracellular
1.04 9.27e-03 GO:0044424 intracellular part
1.17 9.77e-03 GO:0031981 nuclear lumen
1.05 2.05e-02 GO:0043229 intracellular organelle
1.66 2.49e-02 GO:0016607 nuclear speck
1.05 2.81e-02 GO:0043226 organelle
1.47 3.98e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.31 4.08e-04 GO:0003723 RNA binding
1.12 6.09e-03 GO:0003676 nucleic acid binding
1.07 9.67e-03 GO:0005515 protein binding
1.04 4.17e-02 GO:0005488 binding