Motif ID: PATZ1.p2

Z-value: 0.738


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300715650.486.1e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_5289079 1.689 NM_001040661
NM_153247
 SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr21_+_46226072 1.490 NM_001848
 COL6A1
collagen, type VI, alpha 1
chr19_+_56506907 1.385 NM_001101372
 IGLON5
IgLON family member 5
chr20_-_30535045 1.365 C20orf112
chromosome 20 open reading frame 112
chr6_+_37245860 1.314 NM_002648
 PIM1
pim-1 oncogene
chr2_+_42128521 1.313 NM_138370
 PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr20_-_30534848 1.300 NM_080616
 C20orf112
chromosome 20 open reading frame 112
chr5_-_1165106 1.280 NM_006598
 SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr13_-_113066366 1.090 NM_024719
 GRTP1
growth hormone regulated TBC protein 1
chr18_-_24011349 1.087 NM_001792
 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr14_-_20636568 1.083 NM_016423
 ZNF219
zinc finger protein 219
chr20_-_62181588 1.068 NM_001039467
 RGS19
regulator of G-protein signaling 19
chr19_-_48835783 1.066 NM_145296
 CADM4
cell adhesion molecule 4
chr3_+_185580554 1.032 NM_003741
 CHRD
chordin
chr16_-_70475381 1.029 ZNF821
zinc finger protein 821
chr19_-_59676153 1.015 NM_145057
 CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr12_+_3056781 0.981 NM_001168320
NM_006675
 TSPAN9

tetraspanin 9

chr19_+_50041424 0.980 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_-_158335241 0.977 IGSF8
immunoglobulin superfamily, member 8
chr9_+_130223046 0.970 CERCAM
cerebral endothelial cell adhesion molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 99 entries
enrichment   p-value GO term description
1.41 2.35e-02 GO:0016569 covalent chromatin modification
1.41 3.38e-02 GO:0016570 histone modification
1.39 8.07e-06 GO:0016568 chromatin modification
1.38 6.95e-10 GO:0010629 negative regulation of gene expression
1.38 1.33e-02 GO:0051129 negative regulation of cellular component organization
1.36 1.41e-07 GO:0045892 negative regulation of transcription, DNA-dependent
1.36 4.60e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.35 1.36e-08 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.35 4.33e-07 GO:0051253 negative regulation of RNA metabolic process
1.33 5.89e-08 GO:0010558 negative regulation of macromolecule biosynthetic process
1.31 2.09e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 2.50e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.30 8.81e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.30 9.50e-07 GO:0009890 negative regulation of biosynthetic process
1.30 4.82e-04 GO:0031175 neuron projection development
1.29 6.37e-09 GO:0010605 negative regulation of macromolecule metabolic process
1.29 2.48e-03 GO:0048812 neuron projection morphogenesis
1.29 7.24e-03 GO:0007409 axonogenesis
1.27 5.31e-08 GO:0009892 negative regulation of metabolic process
1.27 3.88e-07 GO:0031324 negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
1.53 1.68e-02 GO:0016585 chromatin remodeling complex
1.44 1.69e-03 GO:0070161 anchoring junction
1.40 3.15e-02 GO:0005912 adherens junction
1.34 2.55e-02 GO:0000228 nuclear chromosome
1.29 4.00e-06 GO:0044431 Golgi apparatus part
1.29 8.10e-05 GO:0000139 Golgi membrane
1.28 4.46e-02 GO:0015629 actin cytoskeleton
1.26 5.01e-09 GO:0005794 Golgi apparatus
1.20 9.44e-03 GO:0015630 microtubule cytoskeleton
1.18 8.23e-10 GO:0044428 nuclear part
1.17 2.98e-06 GO:0012505 endomembrane system
1.17 3.66e-02 GO:0031982 vesicle
1.17 4.00e-02 GO:0031410 cytoplasmic vesicle
1.17 4.81e-02 GO:0031988 membrane-bounded vesicle
1.16 3.56e-06 GO:0031981 nuclear lumen
1.15 2.80e-06 GO:0005829 cytosol
1.15 4.61e-03 GO:0005654 nucleoplasm
1.14 4.72e-02 GO:0005783 endoplasmic reticulum
1.13 7.30e-17 GO:0005634 nucleus
1.13 3.02e-05 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
1.88 1.11e-03 GO:0008013 beta-catenin binding
1.50 1.26e-02 GO:0051020 GTPase binding
1.30 1.41e-05 GO:0008092 cytoskeletal protein binding
1.30 7.35e-03 GO:0003779 actin binding
1.29 1.39e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.29 5.80e-06 GO:0004672 protein kinase activity
1.29 6.23e-04 GO:0004674 protein serine/threonine kinase activity
1.28 1.68e-07 GO:0016301 kinase activity
1.28 4.55e-07 GO:0019899 enzyme binding
1.28 4.32e-02 GO:0016564 transcription repressor activity
1.27 5.02e-03 GO:0019904 protein domain specific binding
1.25 9.54e-07 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.24 2.62e-02 GO:0030695 GTPase regulator activity
1.23 1.26e-03 GO:0043565 sequence-specific DNA binding
1.23 4.88e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.21 2.50e-05 GO:0030528 transcription regulator activity
1.20 1.52e-04 GO:0001071 nucleic acid binding transcription factor activity
1.20 1.52e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.19 2.33e-02 GO:0042802 identical protein binding
1.15 2.86e-04 GO:0016740 transferase activity