Motif ID: PATZ1.p2

Z-value: 0.738


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300715650.486.1e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_5289079 1.689 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr21_+_46226072 1.490 NM_001848
COL6A1
collagen, type VI, alpha 1
chr19_+_56506907 1.385 NM_001101372
IGLON5
IgLON family member 5
chr20_-_30535045 1.365 C20orf112
chromosome 20 open reading frame 112
chr6_+_37245860 1.314 NM_002648
PIM1
pim-1 oncogene
chr2_+_42128521 1.313 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr20_-_30534848 1.300 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr5_-_1165106 1.280 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr13_-_113066366 1.090 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr18_-_24011349 1.087 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr14_-_20636568 1.083 NM_016423
ZNF219
zinc finger protein 219
chr20_-_62181588 1.068 NM_001039467
RGS19
regulator of G-protein signaling 19
chr19_-_48835783 1.066 NM_145296
CADM4
cell adhesion molecule 4
chr3_+_185580554 1.032 NM_003741
CHRD
chordin
chr16_-_70475381 1.029 ZNF821
zinc finger protein 821
chr19_-_59676153 1.015 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr12_+_3056781 0.981 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr19_+_50041424 0.980 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_-_158335241 0.977 IGSF8
immunoglobulin superfamily, member 8
chr9_+_130223046 0.970 CERCAM
cerebral endothelial cell adhesion molecule
chr18_-_24010944 0.953 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chrX_-_1291526 0.950 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr7_+_72720093 0.948 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr1_-_158334983 0.945 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chrX_+_9392980 0.936 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr20_-_3102169 0.933 ProSAPiP1
ProSAPiP1 protein
chr10_+_114699953 0.904 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr12_+_55808514 0.902 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr14_-_20636337 0.879 ZNF219
zinc finger protein 219
chr19_+_50041232 0.878 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr19_+_59064471 0.878 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr20_-_62181231 0.866 NM_005873
RGS19
regulator of G-protein signaling 19
chr22_+_49459935 0.865 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chrX_+_152643516 0.856 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr7_+_72720256 0.853 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr19_+_47040863 0.850 NM_001040283
DMRTC2
DMRT-like family C2
chr19_+_40213431 0.826 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr9_-_125732005 0.825 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr19_-_55524445 0.813 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chrX_+_138060 0.810 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr1_-_11637325 0.809 NM_012168
FBXO2
F-box protein 2
chr17_+_52688842 0.805 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr16_-_88613287 0.804 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr8_-_144722141 0.796 C8orf73
chromosome 8 open reading frame 73
chr4_+_1764802 0.792 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr19_+_59064795 0.791 MYADM
myeloid-associated differentiation marker
chr1_-_23623713 0.789 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr1_-_11637058 0.785 FBXO2
F-box protein 2
chr20_+_3661316 0.769 NM_001197327
NM_052970
HSPA12B

heat shock 70kD protein 12B

chr16_+_88542639 0.768 NM_017702
NM_207514
DEF8

differentially expressed in FDCP 8 homolog (mouse)

chr19_+_59062962 0.763 MYADM
myeloid-associated differentiation marker
chr1_-_158334885 0.762 IGSF8
immunoglobulin superfamily, member 8
chr17_-_76622967 0.758 FLJ90757
hypothetical LOC440465
chr4_+_3264509 0.757 RGS12
regulator of G-protein signaling 12
chr7_-_51351825 0.755 COBL
cordon-bleu homolog (mouse)
chr7_-_100077072 0.751 NM_003227
TFR2
transferrin receptor 2
chr12_-_47468985 0.749 NM_020983
ADCY6
adenylate cyclase 6
chr19_+_61344501 0.743 ZNF444
zinc finger protein 444
chr9_+_130222943 0.735 CERCAM
cerebral endothelial cell adhesion molecule
chr20_+_34357604 0.723 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr7_-_158073121 0.717 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_+_38979502 0.711 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr15_+_78232194 0.710 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr11_+_65443303 0.709 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_61344341 0.708 NM_018337
ZNF444
zinc finger protein 444
chr17_+_34114924 0.708 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_30014993 0.703 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr22_-_19122107 0.702 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr19_-_1518875 0.699 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr22_-_19122047 0.689 SCARF2
scavenger receptor class F, member 2
chr15_+_78232232 0.686 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr22_+_48951286 0.684 NM_001160300
NM_052839
PANX2

pannexin 2

chr11_+_56984702 0.682 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr1_-_11636983 0.674 FBXO2
F-box protein 2
chr14_+_20608179 0.665 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr14_-_37134191 0.663 NM_004496
FOXA1
forkhead box A1
chr12_+_6800950 0.662 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr19_+_18069596 0.662 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr3_-_52419086 0.661 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr17_-_73636362 0.660 TMC6
transmembrane channel-like 6
chr5_+_172193826 0.657 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr9_+_137511448 0.657 NM_014811
KIAA0649
KIAA0649
chr2_-_218551786 0.653 TNS1
tensin 1
chr19_+_59062937 0.652 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr17_+_56832255 0.644 TBX2
T-box 2
chr11_-_74914514 0.641 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chrX_+_2756810 0.634 NM_001079855
NM_001184702
NM_001184703
NM_001184704
NM_003918
GYG2




glycogenin 2




chr20_-_51644187 0.631 ZNF217
zinc finger protein 217
chr17_+_34115383 0.630 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_55896844 0.626 NM_007224
NXPH4
neurexophilin 4
chr3_-_14964403 0.625


chr11_+_359723 0.624 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr16_-_11257539 0.621 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr17_-_75385371 0.618 NM_020649
CBX8
chromobox homolog 8
chr11_-_60819110 0.617 VWCE
von Willebrand factor C and EGF domains
chr16_-_51138306 0.616 NM_001080430
TOX3
TOX high mobility group box family member 3
chr2_-_200030944 0.615 NM_001172509
SATB2
SATB homeobox 2
chr19_-_52426055 0.608 NM_014417
BBC3
BCL2 binding component 3
chr15_+_78232160 0.607 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr14_+_104852225 0.607 PACS2
phosphofurin acidic cluster sorting protein 2
chr2_+_218896219 0.605 PNKD
paroxysmal nonkinesigenic dyskinesia
chr7_+_6622051 0.603 NM_017560
ZNF853
zinc finger protein 853
chr12_+_2774550 0.601 FKBP4
FK506 binding protein 4, 59kDa
chr19_+_52451642 0.600 CCDC9
coiled-coil domain containing 9
chr5_+_109052945 0.598 MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_-_39632845 0.597 ATXN7L3
ataxin 7-like 3
chr11_-_60819273 0.597 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr1_-_21868380 0.596 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_+_7891884 0.595 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr7_-_103417198 0.595 NM_005045
NM_173054
RELN

reelin

chr14_-_21064182 0.590 SALL2
sal-like 2 (Drosophila)
chr9_-_129370954 0.588 FAM129B
family with sequence similarity 129, member B
chr20_+_4077409 0.583 NM_175839
NM_175840
NM_175841
NM_175842
SMOX



spermine oxidase



chr10_-_95350949 0.578 NM_006744
RBP4
retinol binding protein 4, plasma
chr20_+_4077466 0.574 SMOX
spermine oxidase
chr1_+_243200251 0.570 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr2_+_63131466 0.569 NM_014562
OTX1
orthodenticle homeobox 1
chr20_+_60906605 0.568 NM_007346
OGFR
opioid growth factor receptor
chr19_-_18578631 0.567 NM_004750
CRLF1
cytokine receptor-like factor 1
chr17_+_44429748 0.567 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr16_+_49139694 0.561 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr6_+_44203335 0.559 NM_018426
TMEM63B
transmembrane protein 63B
chr16_-_49742651 0.558 NM_002968
SALL1
sal-like 1 (Drosophila)
chr16_+_1299180 0.555 NM_194261
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr19_-_18578577 0.553 CRLF1
cytokine receptor-like factor 1
chr16_+_87741416 0.551


chr6_-_44203155 0.549 NM_032111
MRPL14
mitochondrial ribosomal protein L14
chr17_-_7061641 0.545 NM_001128827
DLG4
discs, large homolog 4 (Drosophila)
chr2_-_166940710 0.545 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr17_-_34157962 0.543 NM_007144
PCGF2
polycomb group ring finger 2
chr20_+_30813851 0.542 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr2_-_42574587 0.541 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr6_-_41855564 0.533 NM_006653
FRS3
fibroblast growth factor receptor substrate 3
chr19_+_54708389 0.533 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_87047159 0.531 ZFPM1
zinc finger protein, multitype 1
chr3_+_50279993 0.531 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr15_-_43267441 0.530 SHF
Src homology 2 domain containing F
chr12_-_123023312 0.527 CCDC92
coiled-coil domain containing 92
chr16_-_29817841 0.526 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr16_+_29892714 0.523 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr16_+_88422354 0.522 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr2_+_218896102 0.521 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr20_+_29526751 0.520 NM_014012
REM1
RAS (RAD and GEM)-like GTP-binding 1
chr19_+_40223249 0.518 NM_002151
NM_182983
HPN

hepsin

chr1_+_224317036 0.516 NM_002107
H3F3A
H3 histone, family 3A
chr16_+_1299361 0.514 NM_194260
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr12_+_55808696 0.513 LRP1
low density lipoprotein receptor-related protein 1
chr20_-_22512893 0.512 FOXA2
forkhead box A2
chr1_-_44912704 0.511 TMEM53
transmembrane protein 53
chr14_-_37134050 0.510 FOXA1
forkhead box A1
chr11_-_64247230 0.510 NM_015080
NM_138732
NRXN2

neurexin 2

chr3_+_185536376 0.510 NM_001171093
FAM131A
family with sequence similarity 131, member A
chr11_-_70641267 0.509 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr19_+_47480445 0.508 NM_015125
CIC
capicua homolog (Drosophila)
chr19_-_41215380 0.508 CLIP3
CAP-GLY domain containing linker protein 3
chr9_+_130222511 0.506 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr17_+_7252225 0.506 NM_020795
NLGN2
neuroligin 2
chr17_-_38978253 0.506 ETV4
ets variant 4
chr22_+_47350781 0.505 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr16_+_29730909 0.505 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr3_+_13496714 0.504 NM_024827
NM_001136041
HDAC11

histone deacetylase 11

chr19_+_52451570 0.503 NM_015603
CCDC9
coiled-coil domain containing 9
chr2_-_239987629 0.503 HDAC4
histone deacetylase 4
chr9_+_136358145 0.502 RXRA
retinoid X receptor, alpha
chr22_+_49293520 0.502 NCAPH2
non-SMC condensin II complex, subunit H2
chr19_-_14062230 0.500 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr20_+_62181878 0.500 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr19_+_12995782 0.499 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr22_-_30072329 0.498 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr1_-_32574185 0.496 NM_023009
MARCKSL1
MARCKS-like 1
chr19_+_40958206 0.496 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr20_+_30814048 0.495 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr7_+_73080362 0.495 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr2_+_70981233 0.495 VAX2
ventral anterior homeobox 2
chr19_+_11327061 0.490 NM_001170635
NM_022737
LPPR2

lipid phosphate phosphatase-related protein type 2

chr2_-_216008689 0.490 FN1
fibronectin 1
chr11_-_86343859 0.489 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr7_+_100156358 0.489 NM_000799
EPO
erythropoietin
chr1_+_160306093 0.488 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr20_-_17610704 0.486 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr15_-_43267139 0.486 SHF
Src homology 2 domain containing F
chr9_+_132961723 0.484 AIF1L
allograft inflammatory factor 1-like
chr3_-_14964620 0.483


chr10_+_134201262 0.482 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr7_-_74705276 0.481 NM_001145064
GATSL2
GATS protein-like 2
chr17_-_78249750 0.480 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr19_+_59062982 0.479 MYADM
myeloid-associated differentiation marker
chr8_+_145700272 0.479 NM_005309
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
chr6_+_7053183 0.478 RREB1
ras responsive element binding protein 1
chr16_+_31036474 0.478 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr12_+_56621711 0.475 NM_033276
XRCC6BP1
XRCC6 binding protein 1
chr5_+_176446425 0.474 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr18_+_44319365 0.474 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr6_-_44203131 0.474 MRPL14
mitochondrial ribosomal protein L14
chr17_-_40401138 0.472 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr2_+_112372671 0.472 MERTK
c-mer proto-oncogene tyrosine kinase
chr14_-_20636909 0.469 NM_001101672
ZNF219
zinc finger protein 219
chr1_-_54644663 0.469 NM_001009955
SSBP3
single stranded DNA binding protein 3
chr17_-_63965156 0.468 NM_017983
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr17_-_38978772 0.467 NM_001986
ETV4
ets variant 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 2.41e-22 GO:0009987 cellular process
1.11 1.96e-13 GO:0044237 cellular metabolic process
1.14 1.08e-12 GO:0044260 cellular macromolecule metabolic process
1.10 2.32e-12 GO:0050794 regulation of cellular process
1.16 2.33e-11 GO:0016043 cellular component organization
1.08 5.35e-11 GO:0065007 biological regulation
1.38 6.95e-10 GO:0010629 negative regulation of gene expression
1.09 8.07e-10 GO:0008152 metabolic process
1.14 1.14e-09 GO:0071840 cellular component organization or biogenesis
1.08 1.20e-09 GO:0050789 regulation of biological process
1.09 3.17e-09 GO:0044238 primary metabolic process
1.20 3.67e-09 GO:0006464 protein modification process
1.29 6.37e-09 GO:0010605 negative regulation of macromolecule metabolic process
1.16 8.65e-09 GO:0071842 cellular component organization at cellular level
1.35 1.36e-08 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.18 1.77e-08 GO:0048523 negative regulation of cellular process
1.13 2.39e-08 GO:0031323 regulation of cellular metabolic process
1.27 5.31e-08 GO:0009892 negative regulation of metabolic process
1.33 5.89e-08 GO:0010558 negative regulation of macromolecule biosynthetic process
1.10 9.20e-08 GO:0043170 macromolecule metabolic process
1.16 9.39e-08 GO:0044267 cellular protein metabolic process
1.36 1.41e-07 GO:0045892 negative regulation of transcription, DNA-dependent
1.27 3.88e-07 GO:0031324 negative regulation of cellular metabolic process
1.35 4.33e-07 GO:0051253 negative regulation of RNA metabolic process
1.12 4.43e-07 GO:0080090 regulation of primary metabolic process
1.15 4.71e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.18 6.79e-07 GO:0043412 macromolecule modification
1.30 8.81e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.25 9.30e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 9.50e-07 GO:0009890 negative regulation of biosynthetic process
1.11 1.05e-06 GO:0019222 regulation of metabolic process
1.31 2.09e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 2.50e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.15 2.93e-06 GO:0048519 negative regulation of biological process
1.15 3.96e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.14 4.24e-06 GO:0010468 regulation of gene expression
1.12 7.03e-06 GO:0060255 regulation of macromolecule metabolic process
1.39 8.07e-06 GO:0016568 chromatin modification
1.14 1.01e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 1.04e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.25 2.12e-05 GO:0016265 death
1.13 2.13e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.25 2.27e-05 GO:0008219 cell death
1.36 4.60e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.14 7.42e-05 GO:0051252 regulation of RNA metabolic process
1.18 1.13e-04 GO:0007399 nervous system development
1.13 1.35e-04 GO:0031326 regulation of cellular biosynthetic process
1.17 1.54e-04 GO:0006996 organelle organization
1.14 2.02e-04 GO:0006355 regulation of transcription, DNA-dependent
1.12 2.64e-04 GO:0009889 regulation of biosynthetic process
1.30 4.82e-04 GO:0031175 neuron projection development
1.22 1.09e-03 GO:0048699 generation of neurons
1.10 1.53e-03 GO:0051179 localization
1.11 1.64e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 1.74e-03 GO:0044249 cellular biosynthetic process
1.21 1.82e-03 GO:0022008 neurogenesis
1.13 1.90e-03 GO:0030154 cell differentiation
1.15 2.18e-03 GO:0034645 cellular macromolecule biosynthetic process
1.16 2.24e-03 GO:0009653 anatomical structure morphogenesis
1.11 2.25e-03 GO:0019538 protein metabolic process
1.29 2.48e-03 GO:0048812 neuron projection morphogenesis
1.16 2.54e-03 GO:0009966 regulation of signal transduction
1.24 2.68e-03 GO:0030030 cell projection organization
1.20 2.70e-03 GO:0048468 cell development
1.15 2.82e-03 GO:0009059 macromolecule biosynthetic process
1.19 2.91e-03 GO:0007049 cell cycle
1.10 3.18e-03 GO:0051234 establishment of localization
1.12 3.27e-03 GO:0048522 positive regulation of cellular process
1.21 3.75e-03 GO:0006351 transcription, DNA-dependent
1.19 3.96e-03 GO:0006793 phosphorus metabolic process
1.19 3.96e-03 GO:0006796 phosphate metabolic process
1.23 4.06e-03 GO:0030182 neuron differentiation
1.10 4.24e-03 GO:0006810 transport
1.16 5.16e-03 GO:0035556 intracellular signal transduction
1.11 7.04e-03 GO:0009058 biosynthetic process
1.29 7.24e-03 GO:0007409 axonogenesis
1.12 7.81e-03 GO:0048869 cellular developmental process
1.22 8.03e-03 GO:0012501 programmed cell death
1.25 8.87e-03 GO:0048666 neuron development
1.26 1.00e-02 GO:0048858 cell projection morphogenesis
1.09 1.20e-02 GO:0007275 multicellular organismal development
1.38 1.33e-02 GO:0051129 negative regulation of cellular component organization
1.21 1.40e-02 GO:0006915 apoptosis
1.09 1.48e-02 GO:0032502 developmental process
1.26 1.48e-02 GO:0032990 cell part morphogenesis
1.27 1.57e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.20 1.68e-02 GO:0016310 phosphorylation
1.15 1.84e-02 GO:0033036 macromolecule localization
1.09 2.17e-02 GO:0048856 anatomical structure development
1.41 2.35e-02 GO:0016569 covalent chromatin modification
1.20 2.40e-02 GO:0016192 vesicle-mediated transport
1.10 2.46e-02 GO:0048731 system development
1.21 2.67e-02 GO:0006468 protein phosphorylation
1.09 3.27e-02 GO:0034641 cellular nitrogen compound metabolic process
1.41 3.38e-02 GO:0016570 histone modification
1.13 3.65e-02 GO:0023051 regulation of signaling
1.22 3.73e-02 GO:0051726 regulation of cell cycle
1.25 4.08e-02 GO:0000904 cell morphogenesis involved in differentiation
1.22 4.93e-02 GO:0051276 chromosome organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.94e-36 GO:0005622 intracellular
1.09 1.06e-33 GO:0044424 intracellular part
1.10 5.35e-25 GO:0043227 membrane-bounded organelle
1.10 1.17e-24 GO:0043231 intracellular membrane-bounded organelle
1.11 3.97e-24 GO:0005737 cytoplasm
1.09 5.26e-24 GO:0043226 organelle
1.09 1.20e-23 GO:0043229 intracellular organelle
1.13 7.30e-17 GO:0005634 nucleus
1.11 3.53e-13 GO:0044444 cytoplasmic part
1.18 8.23e-10 GO:0044428 nuclear part
1.26 5.01e-09 GO:0005794 Golgi apparatus
1.10 8.04e-09 GO:0044446 intracellular organelle part
1.09 1.22e-08 GO:0044422 organelle part
1.03 1.75e-08 GO:0005623 cell
1.03 2.11e-08 GO:0044464 cell part
1.15 2.80e-06 GO:0005829 cytosol
1.17 2.98e-06 GO:0012505 endomembrane system
1.16 3.56e-06 GO:0031981 nuclear lumen
1.29 4.00e-06 GO:0044431 Golgi apparatus part
1.13 3.02e-05 GO:0043233 organelle lumen
1.13 3.58e-05 GO:0070013 intracellular organelle lumen
1.29 8.10e-05 GO:0000139 Golgi membrane
1.13 8.91e-05 GO:0031974 membrane-enclosed lumen
1.12 1.46e-03 GO:0031090 organelle membrane
1.44 1.69e-03 GO:0070161 anchoring junction
1.09 4.35e-03 GO:0043234 protein complex
1.15 4.61e-03 GO:0005654 nucleoplasm
1.20 9.44e-03 GO:0015630 microtubule cytoskeleton
1.53 1.68e-02 GO:0016585 chromatin remodeling complex
1.34 2.55e-02 GO:0000228 nuclear chromosome
1.40 3.15e-02 GO:0005912 adherens junction
1.17 3.66e-02 GO:0031982 vesicle
1.17 4.00e-02 GO:0031410 cytoplasmic vesicle
1.28 4.46e-02 GO:0015629 actin cytoskeleton
1.14 4.72e-02 GO:0005783 endoplasmic reticulum
1.17 4.81e-02 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 2.47e-29 GO:0005515 protein binding
1.07 2.46e-23 GO:0005488 binding
1.29 1.39e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 1.68e-07 GO:0016301 kinase activity
1.28 4.55e-07 GO:0019899 enzyme binding
1.25 9.54e-07 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.29 5.80e-06 GO:0004672 protein kinase activity
1.30 1.41e-05 GO:0008092 cytoskeletal protein binding
1.21 2.50e-05 GO:0030528 transcription regulator activity
1.11 9.35e-05 GO:0003676 nucleic acid binding
1.20 1.52e-04 GO:0001071 nucleic acid binding transcription factor activity
1.20 1.52e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.13 1.81e-04 GO:0003677 DNA binding
1.15 2.86e-04 GO:0016740 transferase activity
1.29 6.23e-04 GO:0004674 protein serine/threonine kinase activity
1.12 8.82e-04 GO:0000166 nucleotide binding
1.88 1.11e-03 GO:0008013 beta-catenin binding
1.23 1.26e-03 GO:0043565 sequence-specific DNA binding
1.27 5.02e-03 GO:0019904 protein domain specific binding
1.30 7.35e-03 GO:0003779 actin binding
1.50 1.26e-02 GO:0051020 GTPase binding
1.12 1.76e-02 GO:0017076 purine nucleotide binding
1.12 1.78e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.19 2.33e-02 GO:0042802 identical protein binding
1.11 2.55e-02 GO:0032553 ribonucleotide binding
1.11 2.55e-02 GO:0032555 purine ribonucleotide binding
1.24 2.62e-02 GO:0030695 GTPase regulator activity
1.13 2.80e-02 GO:0030554 adenyl nucleotide binding
1.06 2.91e-02 GO:0003824 catalytic activity
1.28 4.32e-02 GO:0016564 transcription repressor activity
1.13 4.41e-02 GO:0005524 ATP binding
1.23 4.88e-02 GO:0060589 nucleoside-triphosphatase regulator activity