Motif ID: EHF.p2

Z-value: 1.108


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_34599227-0.283.0e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_174968595 3.040 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr6_-_166676016 3.012 SFT2D1
SFT2 domain containing 1
chrX_-_7855400 2.908 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chrX_-_7855764 2.907 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr10_-_15942461 2.467 NM_024948
FAM188A
family with sequence similarity 188, member A
chr16_-_20725272 2.345 NM_001142725
NM_080663
ERI2

ERI1 exoribonuclease family member 2

chr1_+_167604056 2.212 BLZF1
basic leucine zipper nuclear factor 1
chr1_-_111308017 2.209 NM_001006945
NM_018372
C1orf103

chromosome 1 open reading frame 103

chr5_+_158622843 2.186 UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr5_-_87600371 2.105 NM_153354
TMEM161B
transmembrane protein 161B
chr5_+_69732561 2.083 SMA4
glucuronidase, beta pseudogene
chr17_+_55139807 2.059 VMP1
vacuole membrane protein 1
chr6_-_166675980 2.004 NM_145169
SFT2D1
SFT2 domain containing 1
chr5_+_93980108 1.979 NM_032290
ANKRD32
ankyrin repeat domain 32
chr7_-_135312574 1.977 MTPN
myotrophin
chr15_-_63596656 1.951 NM_197960
DPP8
dipeptidyl-peptidase 8
chr2_-_27147995 1.940 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr9_-_85761472 1.912 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr1_-_164004611 1.895 TMCO1
transmembrane and coiled-coil domains 1
chr10_+_12278185 1.874 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr7_-_91713044 1.867 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr18_-_17434581 1.866 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr9_-_114520118 1.863 C9orf80
chromosome 9 open reading frame 80
chr1_+_211291153 1.849 NM_001136138
NM_012424
RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1

chr7_+_107997527 1.844 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr18_-_17434655 1.831 NM_052911
ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr2_-_37047113 1.830 NM_003162
STRN
striatin, calmodulin binding protein
chr12_+_51979721 1.811 NM_021640
C12orf10
chromosome 12 open reading frame 10
chr3_+_151747266 1.775 EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chrX_-_15782826 1.762


chr8_+_38153453 1.750 BAG4
BCL2-associated athanogene 4
chrX_+_11039326 1.720 NM_001122608
NM_001171991
NM_005333
HCCS


holocytochrome c synthase


chrX_+_11039380 1.701 HCCS
holocytochrome c synthase
chr14_+_95899541 1.695 C14orf129
chromosome 14 open reading frame 129
chr5_+_132230214 1.667 NM_014402
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr8_-_95634845 1.660 NM_015496
NM_183009
KIAA1429

KIAA1429

chr6_-_108688918 1.658 SNX3
sorting nexin 3
chr4_-_84031358 1.631 NM_001191049
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_-_230494862 1.630 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr8_+_38153223 1.623 NM_004874
BAG4
BCL2-associated athanogene 4
chr5_+_10303410 1.608 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr6_-_28475478 1.601 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr1_+_39229474 1.600 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr13_+_45524950 1.595


chr7_-_128482417 1.593 NM_001191028
NM_012470
TNPO3

transportin 3

chr19_+_6415259 1.587 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr7_-_91713232 1.583 NM_194455
NM_194456
KRIT1

KRIT1, ankyrin repeat containing

chr17_+_55139841 1.576 VMP1
vacuole membrane protein 1
chr10_+_12277935 1.523 NM_006023
CDC123
cell division cycle 123 homolog (S. cerevisiae)
chrX_-_131179598 1.521 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr11_+_8660913 1.520 RPL27A
ribosomal protein L27a
chr3_-_28365284 1.519 AZI2
5-azacytidine induced 2
chr1_-_54291378 1.512 TMEM59
transmembrane protein 59
chr9_+_37110535 1.510 ZCCHC7
zinc finger, CCHC domain containing 7
chr16_-_70400040 1.510 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_-_164004730 1.507 NM_019026
TMCO1
transmembrane and coiled-coil domains 1
chr1_-_234834410 1.494 NM_018072
HEATR1
HEAT repeat containing 1
chr1_+_118273887 1.482 NM_006784
WDR3
WD repeat domain 3
chr6_-_28663045 1.479 NM_052923
SCAND3
SCAN domain containing 3
chr14_-_23771401 1.469 NM_006156
NEDD8
neural precursor cell expressed, developmentally down-regulated 8
chr9_+_33254876 1.461 NM_001195536
NM_016410
CHMP5

chromatin modifying protein 5

chr17_+_55139793 1.457 VMP1
vacuole membrane protein 1
chr3_+_151747204 1.454 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr2_+_187162969 1.445 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr3_+_15444056 1.434 NM_033083
EAF1
ELL associated factor 1
chr1_-_9925908 1.429 LZIC
leucine zipper and CTNNBIP1 domain containing
chr2_+_3600784 1.428 RPS7
ribosomal protein S7
chr12_+_99185289 1.428 SCYL2
SCY1-like 2 (S. cerevisiae)
chr4_+_186554958 1.425 ANKRD37
ankyrin repeat domain 37
chr20_-_33750457 1.420 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_-_9613191 1.418 ADAM17
ADAM metallopeptidase domain 17
chr1_+_153513810 1.418 NM_020897
HCN3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr16_+_20725267 1.412 NM_001144924
NM_001199053
NM_030941
LOC81691


exonuclease NEF-sp


chr1_+_43628136 1.410 NM_001012961
C1orf84
chromosome 1 open reading frame 84
chr5_+_158622666 1.404 NM_145049
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr7_-_135312734 1.402 NM_145808
NM_001128619
MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr2_+_176842368 1.394 NM_006554
MTX2
metaxin 2
chr17_-_55139538 1.393 NM_016077
PTRH2
peptidyl-tRNA hydrolase 2
chr17_+_55139743 1.389 VMP1
vacuole membrane protein 1
chr6_+_34833244 1.383 SNRPC
small nuclear ribonucleoprotein polypeptide C
chr2_+_9481224 1.379 CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
chr15_+_41450642 1.370 TUBGCP4
tubulin, gamma complex associated protein 4
chr16_+_20725511 1.361 LOC81691
exonuclease NEF-sp
chr6_-_108688860 1.359 SNX3
sorting nexin 3
chr2_-_43676603 1.353 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chrX_+_150316351 1.347 VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_+_216525267 1.343 RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr9_-_114520184 1.334 NM_021218
C9orf80
chromosome 9 open reading frame 80
chr10_+_97879645 1.329 ZNF518A
zinc finger protein 518A
chr2_-_9613278 1.321 ADAM17
ADAM metallopeptidase domain 17
chr8_-_59734742 1.313 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr19_-_61324412 1.310 ZNF787
zinc finger protein 787
chr15_+_21361901 1.300 MKRN3
makorin ring finger protein 3
chr16_-_70400232 1.298 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr2_+_88772388 1.294 RPIA
ribose 5-phosphate isomerase A
chr6_+_43711566 1.293 MAD2L1BP
MAD2L1 binding protein
chr1_+_22251706 1.287 NM_001039802
NM_001791
NM_044472
CDC42


cell division cycle 42 (GTP binding protein, 25kDa)


chr6_+_169844161 1.283 NM_001029863
C6orf120
chromosome 6 open reading frame 120
chr2_-_9613336 1.281 NM_003183
ADAM17
ADAM metallopeptidase domain 17
chr6_+_7335011 1.281 NM_031480
RIOK1
RIO kinase 1 (yeast)
chr7_+_98994199 1.280 ZNF655
zinc finger protein 655
chr20_+_29598848 1.279 HM13
histocompatibility (minor) 13
chr6_+_111687174 1.277 NM_153369
KIAA1919
KIAA1919
chr1_-_158268347 1.275 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr7_-_128482354 1.273 TNPO3
transportin 3
chr1_+_42896634 1.270 NM_006347
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr5_-_69917721 1.269 SMA4
glucuronidase, beta pseudogene
chr12_-_91063441 1.269 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_-_59734801 1.263 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr19_+_57492236 1.253 NM_144684
ZNF480
zinc finger protein 480
chr2_-_230494956 1.253 TRIP12
thyroid hormone receptor interactor 12
chr6_+_43711532 1.253 NM_014628
MAD2L1BP
MAD2L1 binding protein
chr3_-_132704339 1.245 NM_007208
MRPL3
mitochondrial ribosomal protein L3
chrX_+_122821217 1.244 NM_001167
XIAP
X-linked inhibitor of apoptosis
chr7_+_99451110 1.244 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr5_+_78944052 1.241 PAPD4
PAP associated domain containing 4
chr11_-_8942577 1.239 TMEM9B
TMEM9 domain family, member B
chr17_-_46692369 1.237 NM_017643
MBTD1
mbt domain containing 1
chr6_-_108688817 1.234 SNX3
sorting nexin 3
chr16_-_23559978 1.231 NM_024675
PALB2
partner and localizer of BRCA2
chr7_+_107171809 1.229 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chrX_-_130792297 1.227 LOC286467
hypothetical LOC286467
chr1_-_71319265 1.224 ZRANB2
zinc finger, RAN-binding domain containing 2
chr10_+_12278200 1.222 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr1_+_202097355 1.217 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr3_-_15443985 1.217 NM_152396
METTL6
methyltransferase like 6
chr21_+_36614347 1.214 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr20_-_36095236 1.212 NM_014657
TTI1
Tel2 interacting protein 1 homolog (S. pombe)
chr17_+_38238970 1.207 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr6_+_28200365 1.204 NM_025231
ZSCAN16
zinc finger and SCAN domain containing 16
chr11_+_123997980 1.202 TBRG1
transforming growth factor beta regulator 1
chr2_+_138975946 1.199


chr4_-_84031329 1.195 SEC31A
SEC31 homolog A (S. cerevisiae)
chr12_-_42438816 1.192 NM_001098615
NM_001098614
NM_031292
PUS7L


pseudouridylate synthase 7 homolog (S. cerevisiae)-like


chr1_+_45822246 1.187 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr20_+_16658608 1.186 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr6_-_49538810 1.182 NM_000255
MUT
methylmalonyl CoA mutase
chr1_+_211291274 1.178 RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr7_-_128482059 1.178 TNPO3
transportin 3
chr17_+_63144500 1.177 NM_015462
NOL11
nucleolar protein 11
chr2_-_44442447 1.176 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr7_+_98994363 1.172 NM_001009958
NM_001009960
NM_001085367
NM_001085368
ZNF655



zinc finger protein 655



chr3_+_159310543 1.168 NM_016625
RSRC1
arginine/serine-rich coiled-coil 1
chr2_+_32356492 1.162 YIPF4
Yip1 domain family, member 4
chr1_-_245401874 1.161 NM_003431
ZNF124
zinc finger protein 124
chr5_+_78943998 1.158 NM_001114393
NM_001114394
NM_173797
PAPD4


PAP associated domain containing 4


chr1_+_202097386 1.158 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr7_+_134997751 1.156 NM_001130929
SLC13A4
PL-5283
solute carrier family 13 (sodium/sulfate symporters), member 4
PL-5283 protein
chr12_+_99185334 1.155 NM_017988
SCYL2
SCY1-like 2 (S. cerevisiae)
chr15_+_21361546 1.148 NM_005664
MKRN3
makorin ring finger protein 3
chr5_-_140051072 1.139 HARS
histidyl-tRNA synthetase
chr16_+_67931033 1.137 NM_016101
NIP7
nuclear import 7 homolog (S. cerevisiae)
chr5_-_60493985 1.132 NM_001048249
C5orf43
chromosome 5 open reading frame 43
chr6_-_32251864 1.129 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr7_+_98994129 1.128 ZNF655
zinc finger protein 655
chr2_+_187163232 1.127 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr6_-_108689000 1.126 NM_003795
NM_152827
SNX3

sorting nexin 3

chr11_+_85690900 1.126 NM_016401
C11orf73
chromosome 11 open reading frame 73
chr1_-_168129606 1.124 SCYL3
SCY1-like 3 (S. cerevisiae)
chr6_-_32251877 1.124 NM_006411
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr1_+_216525251 1.122 NM_016052
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr2_+_122124034 1.122 LOC254128
hypothetical LOC254128
chr4_-_84031294 1.121 SEC31A
SEC31 homolog A (S. cerevisiae)
chr20_+_43028590 1.120 STK4
serine/threonine kinase 4
chr10_+_12278213 1.119 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr5_+_134012133 1.117 NM_021982
SEC24A
SEC24 family, member A (S. cerevisiae)
chr16_-_20725252 1.117 ERI2
ERI1 exoribonuclease family member 2
chr11_-_8942531 1.116 NM_020644
TMEM9B
TMEM9 domain family, member B
chr16_-_11917235 1.111 GSPT1
G1 to S phase transition 1
chr2_+_118562499 1.111 NM_016133
INSIG2
insulin induced gene 2
chr4_-_140224794 1.109 ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_-_57149588 1.103 NM_001023
NM_001146227
RPS20

ribosomal protein S20

chrX_+_146801236 1.102 FMR1
fragile X mental retardation 1
chr5_+_74098828 1.101 NM_014886
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr1_+_32460557 1.099 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr3_-_173010921 1.099 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chr14_+_22368923 1.096 NM_178336
NM_180982
NM_181304
NM_181305
NM_181306
NM_181307
MRPL52





mitochondrial ribosomal protein L52





chr8_+_126054719 1.092 NM_152412
ZNF572
zinc finger protein 572
chr18_-_17434811 1.090 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_+_111450177 1.088 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr9_+_37110506 1.087 ZCCHC7
zinc finger, CCHC domain containing 7
chr6_-_160130679 1.087 TCP1
t-complex 1
chr2_-_70374349 1.086 NM_003096
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr7_+_65843077 1.086 NM_014504
RABGEF1
RAB guanine nucleotide exchange factor (GEF) 1
chr5_+_140051325 1.084 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr10_+_97879457 1.083 NM_014803
ZNF518A
zinc finger protein 518A
chr1_+_22224571 1.081 HSPC157
hypothetical LOC29092
chr14_-_23781328 1.081 TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_10242763 1.079 ICAM1
intercellular adhesion molecule 1
chr6_-_32251773 1.072 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr21_-_32906729 1.071 NM_021254
C21orf59
chromosome 21 open reading frame 59
chr1_+_23942442 1.068 NM_003198
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr2_+_32356460 1.064 NM_032312
YIPF4
Yip1 domain family, member 4
chr4_-_84031396 1.063 NM_001077206
NM_001077207
NM_001077208
NM_016211
NM_014933
SEC31A




SEC31 homolog A (S. cerevisiae)




chr4_-_84031362 1.063 SEC31A
SEC31 homolog A (S. cerevisiae)
chr11_+_32561931 1.059 NM_006360
EIF3M
eukaryotic translation initiation factor 3, subunit M
chr6_+_111409933 1.059 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr19_+_40431678 1.059 LSR
lipolysis stimulated lipoprotein receptor
chr5_-_140051137 1.057 NM_002109
HARS
histidyl-tRNA synthetase
chr9_+_37110468 1.055 NM_032226
ZCCHC7
zinc finger, CCHC domain containing 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 1.73e-40 GO:0044260 cellular macromolecule metabolic process
1.35 3.08e-31 GO:0043170 macromolecule metabolic process
1.59 4.08e-30 GO:0090304 nucleic acid metabolic process
1.27 1.45e-25 GO:0044237 cellular metabolic process
1.47 2.59e-25 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 3.96e-24 GO:0010467 gene expression
1.61 1.05e-23 GO:0016070 RNA metabolic process
1.57 7.40e-20 GO:0034645 cellular macromolecule biosynthetic process
1.56 1.30e-19 GO:0009059 macromolecule biosynthetic process
1.23 4.81e-19 GO:0044238 primary metabolic process
1.43 1.23e-18 GO:0044267 cellular protein metabolic process
1.21 3.40e-18 GO:0008152 metabolic process
2.15 2.45e-17 GO:0016032 viral reproduction
1.36 8.18e-17 GO:0034641 cellular nitrogen compound metabolic process
1.98 1.27e-16 GO:0016071 mRNA metabolic process
1.89 1.40e-16 GO:0006396 RNA processing
1.33 3.95e-15 GO:0006807 nitrogen compound metabolic process
2.02 1.01e-12 GO:0006397 mRNA processing
2.46 1.29e-12 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.46 1.29e-12 GO:0000398 nuclear mRNA splicing, via spliceosome
1.69 2.00e-12 GO:0046907 intracellular transport
2.43 2.24e-12 GO:0000375 RNA splicing, via transesterification reactions
2.13 3.52e-12 GO:0006412 translation
1.65 5.93e-12 GO:0015031 protein transport
1.35 1.63e-11 GO:0044249 cellular biosynthetic process
1.63 2.51e-11 GO:0045184 establishment of protein localization
1.31 3.57e-11 GO:0019538 protein metabolic process
1.32 5.24e-11 GO:0071841 cellular component organization or biogenesis at cellular level
2.37 5.66e-11 GO:0022613 ribonucleoprotein complex biogenesis
1.28 7.00e-11 GO:0071840 cellular component organization or biogenesis
1.44 7.45e-11 GO:0006996 organelle organization
1.54 2.37e-10 GO:0008104 protein localization
1.80 2.87e-10 GO:0006974 response to DNA damage stimulus
2.05 3.40e-10 GO:0008380 RNA splicing
1.32 5.55e-10 GO:0009058 biosynthetic process
2.25 1.48e-09 GO:0071843 cellular component biogenesis at cellular level
1.66 3.15e-08 GO:0009057 macromolecule catabolic process
1.29 3.17e-08 GO:0071842 cellular component organization at cellular level
1.99 5.20e-08 GO:0010608 posttranscriptional regulation of gene expression
1.43 5.75e-08 GO:0033036 macromolecule localization
1.70 9.14e-08 GO:0044265 cellular macromolecule catabolic process
1.25 9.31e-08 GO:0016043 cellular component organization
2.88 4.86e-07 GO:0006353 transcription termination, DNA-dependent
1.28 6.10e-07 GO:0010468 regulation of gene expression
1.46 6.89e-07 GO:0007049 cell cycle
1.41 7.71e-07 GO:0051641 cellular localization
1.80 9.20e-07 GO:0030163 protein catabolic process
1.08 1.10e-06 GO:0009987 cellular process
1.82 1.71e-06 GO:0044257 cellular protein catabolic process
1.43 1.76e-06 GO:0051649 establishment of localization in cell
1.82 2.73e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
1.23 3.15e-06 GO:0060255 regulation of macromolecule metabolic process
1.46 3.43e-06 GO:0032774 RNA biosynthetic process
2.64 3.96e-06 GO:0071826 ribonucleoprotein complex subunit organization
1.83 4.68e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.49 4.77e-06 GO:0033554 cellular response to stress
1.60 5.32e-06 GO:0000278 mitotic cell cycle
1.57 6.62e-06 GO:0051726 regulation of cell cycle
1.81 6.64e-06 GO:0019941 modification-dependent protein catabolic process
1.59 7.48e-06 GO:0006259 DNA metabolic process
2.66 7.98e-06 GO:0022618 ribonucleoprotein complex assembly
1.20 8.88e-06 GO:0019222 regulation of metabolic process
1.80 9.71e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.26 1.29e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.26 2.86e-05 GO:0042254 ribosome biogenesis
1.47 3.30e-05 GO:0022402 cell cycle process
1.69 3.35e-05 GO:0006886 intracellular protein transport
1.60 3.98e-05 GO:0034613 cellular protein localization
2.08 5.07e-05 GO:0006417 regulation of translation
1.25 5.14e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.59 6.04e-05 GO:0070727 cellular macromolecule localization
2.18 6.20e-05 GO:0048193 Golgi vesicle transport
1.93 7.06e-05 GO:0033365 protein localization to organelle
1.76 9.69e-05 GO:0051325 interphase
1.59 1.24e-04 GO:0034621 cellular macromolecular complex subunit organization
1.72 1.26e-04 GO:0070647 protein modification by small protein conjugation or removal
1.19 1.73e-04 GO:0031323 regulation of cellular metabolic process
1.75 1.83e-04 GO:0051329 interphase of mitotic cell cycle
1.37 1.94e-04 GO:0044248 cellular catabolic process
1.27 2.02e-04 GO:0043412 macromolecule modification
2.62 2.37e-04 GO:0072594 establishment of protein localization to organelle
1.46 2.42e-04 GO:0016192 vesicle-mediated transport
1.32 2.57e-04 GO:0009056 catabolic process
1.43 3.10e-04 GO:0043933 macromolecular complex subunit organization
1.69 3.40e-04 GO:0006281 DNA repair
1.76 3.52e-04 GO:0032446 protein modification by small protein conjugation
2.50 3.84e-04 GO:0006354 transcription elongation, DNA-dependent
1.47 4.03e-04 GO:0022403 cell cycle phase
1.27 5.12e-04 GO:0006464 protein modification process
2.20 6.45e-04 GO:0051320 S phase
1.22 6.48e-04 GO:0031326 regulation of cellular biosynthetic process
1.22 6.69e-04 GO:0009889 regulation of biosynthetic process
2.61 7.34e-04 GO:0071158 positive regulation of cell cycle arrest
2.43 8.09e-04 GO:0000216 M/G1 transition of mitotic cell cycle
2.18 1.08e-03 GO:0000084 S phase of mitotic cell cycle
1.82 1.08e-03 GO:0071156 regulation of cell cycle arrest
2.03 1.15e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.83 1.16e-03 GO:0000075 cell cycle checkpoint
1.75 1.39e-03 GO:0016567 protein ubiquitination
1.72 2.11e-03 GO:0034660 ncRNA metabolic process
1.18 2.30e-03 GO:0080090 regulation of primary metabolic process
1.94 2.37e-03 GO:0010498 proteasomal protein catabolic process
1.94 2.37e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.23 2.58e-03 GO:0051252 regulation of RNA metabolic process
2.55 3.40e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.55 3.40e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
2.55 3.40e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.55 3.40e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.55 3.40e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.55 3.40e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
2.55 3.40e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.55 3.40e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.45 3.52e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.27 3.62e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.42 4.46e-03 GO:0006915 apoptosis
1.42 4.61e-03 GO:0012501 programmed cell death
1.38 4.80e-03 GO:0006351 transcription, DNA-dependent
1.37 6.21e-03 GO:0016265 death
2.15 6.22e-03 GO:0006414 translational elongation
1.37 6.72e-03 GO:0008219 cell death
2.10 6.85e-03 GO:0032984 macromolecular complex disassembly
2.10 6.85e-03 GO:0034623 cellular macromolecular complex disassembly
1.65 7.52e-03 GO:0006366 transcription from RNA polymerase II promoter
2.49 8.77e-03 GO:0006368 transcription elongation from RNA polymerase II promoter
2.29 9.37e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.29 9.37e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
2.29 9.37e-03 GO:0071779 G1/S transition checkpoint
2.24 1.04e-02 GO:0051351 positive regulation of ligase activity
2.24 1.04e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.21 1.13e-02 GO:0006415 translational termination
2.04 1.19e-02 GO:0031570 DNA integrity checkpoint
1.59 1.19e-02 GO:0010564 regulation of cell cycle process
2.17 1.22e-02 GO:0006352 transcription initiation, DNA-dependent
1.95 1.22e-02 GO:0010565 regulation of cellular ketone metabolic process
2.06 1.46e-02 GO:0000077 DNA damage checkpoint
3.06 1.66e-02 GO:0000245 spliceosome assembly
1.79 1.67e-02 GO:0022411 cellular component disassembly
1.79 1.67e-02 GO:0071845 cellular component disassembly at cellular level
2.12 1.71e-02 GO:0043241 protein complex disassembly
2.12 1.71e-02 GO:0043624 cellular protein complex disassembly
2.23 1.75e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.56 1.86e-02 GO:0016568 chromatin modification
2.04 1.89e-02 GO:0042770 signal transduction in response to DNA damage
1.19 2.10e-02 GO:0051171 regulation of nitrogen compound metabolic process
2.74 2.19e-02 GO:0006369 termination of RNA polymerase II transcription
1.30 2.33e-02 GO:0044085 cellular component biogenesis
2.30 2.43e-02 GO:0051352 negative regulation of ligase activity
2.30 2.43e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.98 2.48e-02 GO:0031018 endocrine pancreas development
1.73 2.98e-02 GO:0006605 protein targeting
2.32 2.99e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.27 3.34e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.11 3.54e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
2.22 3.67e-02 GO:0031123 RNA 3'-end processing
2.08 3.68e-02 GO:0051340 regulation of ligase activity
1.21 3.92e-02 GO:0006355 regulation of transcription, DNA-dependent
3.63 3.99e-02 GO:0006362 transcription elongation from RNA polymerase I promoter
2.15 4.23e-02 GO:0019080 viral genome expression
2.15 4.23e-02 GO:0019083 viral transcription
2.57 4.49e-02 GO:0006446 regulation of translational initiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 3.82e-69 GO:0044424 intracellular part
1.21 9.41e-68 GO:0005622 intracellular
1.30 5.17e-67 GO:0043231 intracellular membrane-bounded organelle
1.30 7.66e-67 GO:0043227 membrane-bounded organelle
1.26 1.59e-62 GO:0043229 intracellular organelle
1.26 2.54e-62 GO:0043226 organelle
1.39 3.43e-47 GO:0005634 nucleus
1.33 6.40e-35 GO:0044446 intracellular organelle part
1.32 2.90e-33 GO:0044422 organelle part
1.59 3.27e-31 GO:0044428 nuclear part
1.54 5.19e-29 GO:0031974 membrane-enclosed lumen
1.55 1.60e-28 GO:0070013 intracellular organelle lumen
1.54 5.43e-28 GO:0043233 organelle lumen
1.60 1.32e-26 GO:0031981 nuclear lumen
1.19 1.18e-21 GO:0005737 cytoplasm
2.08 4.90e-21 GO:0030529 ribonucleoprotein complex
1.24 1.70e-19 GO:0044444 cytoplasmic part
1.34 1.37e-18 GO:0032991 macromolecular complex
1.59 1.46e-17 GO:0005654 nucleoplasm
1.35 4.02e-10 GO:0005829 cytosol
1.29 1.33e-09 GO:0043228 non-membrane-bounded organelle
1.29 1.33e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.72 5.53e-09 GO:0005730 nucleolus
1.05 3.02e-08 GO:0044464 cell part
1.05 3.22e-08 GO:0005623 cell
1.40 6.80e-08 GO:0005739 mitochondrion
1.55 1.07e-07 GO:0044451 nucleoplasm part
1.25 1.58e-07 GO:0043234 protein complex
2.77 2.06e-07 GO:0071013 catalytic step 2 spliceosome
2.11 2.42e-07 GO:0005840 ribosome
2.29 4.95e-07 GO:0005681 spliceosomal complex
1.27 3.96e-06 GO:0031090 organelle membrane
2.88 2.61e-05 GO:0005798 Golgi-associated vesicle
1.54 2.72e-05 GO:0005694 chromosome
1.48 3.11e-05 GO:0044429 mitochondrial part
1.83 7.78e-05 GO:0016604 nuclear body
1.44 1.43e-04 GO:0031967 organelle envelope
1.37 1.52e-04 GO:0005794 Golgi apparatus
2.07 3.82e-04 GO:0016607 nuclear speck
1.53 3.91e-04 GO:0044427 chromosomal part
1.41 4.72e-04 GO:0031975 envelope
3.24 4.97e-04 GO:0030660 Golgi-associated vesicle membrane
2.47 1.28e-03 GO:0000502 proteasome complex
1.95 1.34e-03 GO:0000151 ubiquitin ligase complex
2.30 2.02e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.35 3.74e-03 GO:0030117 membrane coat
2.35 3.74e-03 GO:0048475 coated membrane
2.80 4.29e-03 GO:0030120 vesicle coat
4.11 7.82e-03 GO:0030663 COPI coated vesicle membrane
1.67 1.25e-02 GO:0000228 nuclear chromosome
2.18 1.46e-02 GO:0022626 cytosolic ribosome
2.10 1.62e-02 GO:0000790 nuclear chromatin
1.43 2.08e-02 GO:0005740 mitochondrial envelope
2.26 2.60e-02 GO:0015934 large ribosomal subunit
1.43 3.44e-02 GO:0031966 mitochondrial membrane
2.78 4.39e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.69 4.73e-02 GO:0044454 nuclear chromosome part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 1.27e-27 GO:0003676 nucleic acid binding
1.78 1.94e-18 GO:0003723 RNA binding
1.18 4.34e-16 GO:0005515 protein binding
1.10 3.76e-14 GO:0005488 binding
1.31 6.64e-08 GO:0008270 zinc ion binding
1.29 8.47e-08 GO:0003677 DNA binding
2.18 2.39e-06 GO:0003735 structural constituent of ribosome
1.25 1.95e-05 GO:0046914 transition metal ion binding
1.54 4.49e-04 GO:0016874 ligase activity
2.34 5.98e-04 GO:0008135 translation factor activity, nucleic acid binding
2.14 1.02e-03 GO:0008026 ATP-dependent helicase activity
2.14 1.02e-03 GO:0070035 purine NTP-dependent helicase activity
1.96 1.57e-03 GO:0004386 helicase activity
1.62 7.80e-03 GO:0016881 acid-amino acid ligase activity
1.52 1.67e-02 GO:0016887 ATPase activity
1.56 1.90e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.63 2.62e-02 GO:0019787 small conjugating protein ligase activity