Motif ID: ZIC1..3.p2

Z-value: 1.175


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC1chr3_+_1486105160.562.5e-02Click!
ZIC3chrX_+_1364763530.351.8e-01Click!
ZIC2chr13_+_99432258-0.107.1e-01Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_85169615 1.823 NM_005250
FOXL1
forkhead box L1
chr3_-_73756668 1.786 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr9_-_112840064 1.375 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr4_-_149582948 1.267 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr17_-_40594652 1.185


chr4_-_149582754 1.175 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr4_+_72271218 1.154 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr5_-_156935283 1.116


chr22_-_26527469 1.036 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr7_+_44110527 1.025 AEBP1
AE binding protein 1
chr7_+_44110470 0.959 NM_001129
AEBP1
AE binding protein 1
chr3_+_139211639 0.935 NM_016369
CLDN18
claudin 18
chr14_+_28306633 0.902 FOXG1
forkhead box G1
chr21_-_27139143 0.870 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr21_-_27139563 0.855 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_-_126375864 0.850 KIRREL3
kin of IRRE like 3 (Drosophila)
chr5_-_168660293 0.842 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr1_-_39877928 0.840 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr3_-_55490401 0.838 WNT5A
wingless-type MMTV integration site family, member 5A
chr14_+_100362204 0.815 MEG3
maternally expressed 3 (non-protein coding)
chr22_+_35777561 0.799 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr19_+_16296632 0.788 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr11_+_111288669 0.781 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr17_+_58058783 0.770 MRC2
mannose receptor, C type 2
chr5_+_150008030 0.766 SYNPO
synaptopodin
chr6_-_169392771 0.766


chr9_-_35948150 0.760 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr1_-_38285033 0.758 NM_002699
POU3F1
POU class 3 homeobox 1
chr17_+_45703765 0.757 NM_001168215
TMEM92
transmembrane protein 92
chr7_+_27190688 0.731


chr17_+_56832492 0.727 TBX2
T-box 2
chr9_+_108665168 0.724 NM_021224
ZNF462
zinc finger protein 462
chr17_+_56884560 0.712 TBX4
T-box 4
chr9_+_112470871 0.712 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr12_-_6668880 0.709 NM_001039917
NM_001039919
NM_001039920
NM_001135734
ZNF384



zinc finger protein 384



chr5_-_156935317 0.708 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr3_-_39209075 0.703 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr12_+_52653176 0.702 NM_014212
HOXC11
homeobox C11
chr3_+_160964574 0.699 SCHIP1
schwannomin interacting protein 1
chr11_+_75056343 0.696


chr2_-_27339278 0.692 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr3_-_197120276 0.690 NM_005781
TNK2
tyrosine kinase, non-receptor, 2
chr2_+_219991342 0.683 NM_001927
DES
desmin
chr16_+_31390567 0.681 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr14_+_64076916 0.679 NM_021979
HSPA2
heat shock 70kDa protein 2
chr20_-_61728774 0.676 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr6_-_29703913 0.674 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr14_+_64077171 0.674 HSPA2
heat shock 70kDa protein 2
chr16_+_30951915 0.670 STX4
syntaxin 4
chr22_-_42589543 0.655 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr1_-_27802947 0.650 AHDC1
AT hook, DNA binding motif, containing 1
chr16_+_54070302 0.646 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr9_+_134027154 0.642 NM_032536
NTNG2
netrin G2
chr17_+_260408 0.639 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr6_+_1335067 0.634 NM_001452
FOXF2
forkhead box F2
chr1_-_39877883 0.631 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr11_-_126375895 0.622 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr5_+_140835788 0.621 PCDHGC3
protocadherin gamma subfamily C, 3
chr11_-_11987115 0.617 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr19_+_60851207 0.614 CCDC106
coiled-coil domain containing 106
chr17_-_40401138 0.613 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr19_+_10900502 0.613 C19orf52
chromosome 19 open reading frame 52
chr14_-_104515738 0.611 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr5_+_140835727 0.608 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr17_+_36515166 0.600 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr17_+_7549138 0.599 NM_001406
EFNB3
ephrin-B3
chr2_+_202607554 0.599 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr7_+_68702252 0.588 AUTS2
autism susceptibility candidate 2
chr3_+_112273464 0.588 NM_015480
PVRL3
poliovirus receptor-related 3
chr15_+_37660568 0.583 NM_003246
THBS1
thrombospondin 1
chr19_+_16296734 0.581 KLF2
Kruppel-like factor 2 (lung)
chr9_+_34980266 0.579 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_+_49013424 0.573 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr8_+_1909437 0.573 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr16_+_65840275 0.565 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr5_+_52812165 0.564 FST
follistatin
chr17_-_40674883 0.563


chr2_+_238673689 0.561 NM_194312
ESPNL
espin-like
chr11_+_64608307 0.560 ZFPL1
zinc finger protein-like 1
chr1_+_179324458 0.552 IER5
immediate early response 5
chr9_-_112840801 0.539 LPAR1
lysophosphatidic acid receptor 1
chr9_+_34979674 0.539 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr22_-_44751671 0.538 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr16_+_85158357 0.531 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr19_+_627346 0.531 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr5_+_175725050 0.529 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr14_+_100362236 0.526 MEG3
maternally expressed 3 (non-protein coding)
chr8_-_22044463 0.522 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr20_-_56859352 0.521 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr7_-_150576660 0.520 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_109883864 0.517 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr13_-_73605914 0.516 NM_007249
KLF12
Kruppel-like factor 12
chr10_-_105202012 0.515 CALHM2
calcium homeostasis modulator 2
chr16_-_2099854 0.514 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr20_+_61798446 0.510 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr14_+_105012106 0.509 NM_001312
CRIP2
cysteine-rich protein 2
chr1_-_234096793 0.508


chr11_-_61415429 0.507 NM_021727
FADS3
fatty acid desaturase 3
chr14_+_85066265 0.506 FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_11986704 0.505 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr12_+_55808514 0.504 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr11_+_19691397 0.503 NM_145117
NM_182964
NAV2

neuron navigator 2

chr15_+_72209039 0.497 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_168899936 0.493 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr1_-_1233109 0.493 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr1_-_40140126 0.493 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr19_+_60487345 0.492 NM_032430
BRSK1
BR serine/threonine kinase 1
chr12_-_50871953 0.491 NM_001081492
NM_182507
KRT80

keratin 80

chr16_-_1999760 0.487 NM_178167
ZNF598
zinc finger protein 598
chr15_+_72208751 0.487 NM_001130136
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_+_131285747 0.485 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr11_-_11987198 0.484 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr3_+_128874458 0.483 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr6_+_45498262 0.483 RUNX2
runt-related transcription factor 2
chr19_-_50987625 0.483 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr19_-_54835162 0.481 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr3_+_50272648 0.481


chr17_-_28644118 0.481 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr2_-_26058831 0.480 KIF3C
kinesin family member 3C
chr7_-_6557591 0.479 NM_001145118
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr13_-_109236897 0.476 NM_003749
IRS2
insulin receptor substrate 2
chr17_-_15185623 0.474 NM_031898
TEKT3
tektin 3
chr19_-_53912025 0.474 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr12_-_3732614 0.473 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr11_-_11600118 0.472 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr17_+_7252225 0.472 NM_020795
NLGN2
neuroligin 2
chr11_-_66898223 0.471 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chrX_-_53367246 0.470 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chrX_+_101792949 0.467 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr17_+_73738985 0.464 NM_001145529
TMEM235
transmembrane protein 235
chr1_+_155130146 0.463 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr8_-_116750427 0.462 TRPS1
trichorhinophalangeal syndrome I
chr6_+_45498354 0.459 RUNX2
runt-related transcription factor 2
chr22_-_17545872 0.457 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_-_27967458 0.453 LOC100302650
hypothetical LOC100302650
chr9_+_101623957 0.453 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr17_-_44010543 0.451 NM_024015
HOXB4
homeobox B4
chrX_+_51944658 0.450 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr12_+_6179736 0.450 NM_001769
CD9
CD9 molecule
chr11_-_110917632 0.449


chr9_-_130912728 0.447 NM_000755
CRAT
carnitine O-acetyltransferase
chr16_+_30952350 0.447 STX4
syntaxin 4
chr11_+_65802221 0.445 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr11_-_111287657 0.444 NM_001885
CRYAB
crystallin, alpha B
chr11_-_65396775 0.442 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr10_+_72102563 0.439 NM_080722
NM_139155
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr3_+_112273352 0.437 PVRL3
poliovirus receptor-related 3
chr1_+_99502655 0.436 LPPR4
lipid phosphate phosphatase-related protein type 4
chr11_+_19328846 0.436 NM_001111018
NAV2
neuron navigator 2
chrX_-_100801472 0.434 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr11_+_111288686 0.433 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr2_-_144991386 0.432 ZEB2
zinc finger E-box binding homeobox 2
chr16_+_87021379 0.430 NM_001127464
ZNF469
zinc finger protein 469
chr19_-_5291700 0.429 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr3_+_139200347 0.429 NM_001002026
CLDN18
claudin 18
chr10_+_75343352 0.428 PLAU
plasminogen activator, urokinase
chr7_+_43118721 0.428 NM_015052
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr1_-_27802688 0.428 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr14_+_102662416 0.428 NM_006291
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr4_-_140696740 0.426 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr9_-_103289154 0.424 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr19_+_60487578 0.424 BRSK1
BR serine/threonine kinase 1
chr11_-_35503720 0.424 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chrX_+_149282097 0.422 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr19_+_7505037 0.422 NM_006702
NM_001166112
PNPLA6

patatin-like phospholipase domain containing 6

chr1_-_35143570 0.422 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr11_-_118055564 0.422 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chr12_-_6668680 0.421 ZNF384
zinc finger protein 384
chr22_-_17546234 0.418 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_-_26058941 0.417 NM_002254
KIF3C
kinesin family member 3C
chr19_-_45611110 0.417 NM_020956
NM_181882
PRX

periaxin

chr17_+_23722689 0.417 SARM1
sterile alpha and TIR motif containing 1
chr7_-_150576634 0.415 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr7_+_100037817 0.415 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr12_+_55808696 0.415 LRP1
low density lipoprotein receptor-related protein 1
chr20_+_25176698 0.414 NM_002862
PYGB
phosphorylase, glycogen; brain
chr12_-_70952572 0.414 LOC283392
hypothetical LOC283392
chr5_-_83715947 0.414 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr7_+_68701704 0.413 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr7_-_27180398 0.412 NM_018951
HOXA10
homeobox A10
chr16_+_3345889 0.412 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr6_+_149109841 0.410 NM_005715
UST
uronyl-2-sulfotransferase
chr6_-_29703725 0.410 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chrX_-_30237403 0.408 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr15_+_41597097 0.408 NM_002373
MAP1A
microtubule-associated protein 1A
chr11_+_112337491 0.407 NCAM1
neural cell adhesion molecule 1
chr19_-_7896974 0.407 NM_206833
CTXN1
cortexin 1
chr3_-_9570412 0.406 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr8_-_124613557 0.405 NM_148177
FBXO32
F-box protein 32
chr1_-_200946038 0.405 NM_177402
SYT2
synaptotagmin II
chr1_+_99502435 0.402 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr17_+_7846636 0.401 NM_000180
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chrX_-_107866262 0.401 NM_003604
IRS4
insulin receptor substrate 4
chr15_+_72315719 0.399 NM_025055
CCDC33
coiled-coil domain containing 33
chr7_-_135063461 0.399 NM_012450
SLC13A4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr2_+_220033777 0.399 NM_001173476
SPEG
SPEG complex locus
chr19_+_482737 0.398 CDC34
cell division cycle 34 homolog (S. cerevisiae)
chr15_-_40236061 0.398 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr16_+_30952382 0.396 NM_004604
STX4
syntaxin 4
chr9_-_139235595 0.395 NM_031297
RNF208
ring finger protein 208

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 4.29e-12 GO:0048856 anatomical structure development
1.40 7.74e-12 GO:0048731 system development
1.33 2.07e-11 GO:0032502 developmental process
1.33 1.92e-10 GO:0007275 multicellular organismal development
1.18 3.19e-08 GO:0050794 regulation of cellular process
1.50 3.88e-08 GO:0007399 nervous system development
1.41 4.42e-08 GO:0030154 cell differentiation
1.40 5.78e-08 GO:0048869 cellular developmental process
1.48 1.28e-07 GO:0009653 anatomical structure morphogenesis
1.16 2.75e-07 GO:0065007 biological regulation
1.21 8.61e-07 GO:0032501 multicellular organismal process
1.16 9.52e-07 GO:0050789 regulation of biological process
1.57 2.81e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.25 4.50e-06 GO:0023052 signaling
1.41 9.92e-06 GO:0023051 regulation of signaling
1.36 3.35e-05 GO:0048513 organ development
1.93 5.37e-05 GO:0045597 positive regulation of cell differentiation
1.42 6.37e-05 GO:0009966 regulation of signal transduction
1.74 9.14e-05 GO:0019226 transmission of nerve impulse
1.74 9.14e-05 GO:0035637 multicellular organismal signaling
1.62 9.77e-05 GO:0045595 regulation of cell differentiation
1.48 1.03e-04 GO:0010646 regulation of cell communication
1.55 1.27e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.52 1.29e-04 GO:0050793 regulation of developmental process
1.53 1.80e-04 GO:0048699 generation of neurons
1.57 1.98e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57 2.13e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 2.21e-04 GO:0009891 positive regulation of biosynthetic process
1.56 2.32e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.50 3.43e-04 GO:0022008 neurogenesis
1.58 3.67e-04 GO:0030182 neuron differentiation
1.85 3.68e-04 GO:0007389 pattern specification process
1.59 4.04e-04 GO:0010628 positive regulation of gene expression
1.55 5.84e-04 GO:2000026 regulation of multicellular organismal development
1.33 7.57e-04 GO:0048583 regulation of response to stimulus
1.42 9.37e-04 GO:0010604 positive regulation of macromolecule metabolic process
2.27 9.44e-04 GO:0043062 extracellular structure organization
1.60 1.03e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.85 1.08e-03 GO:0001501 skeletal system development
1.50 1.12e-03 GO:0009888 tissue development
1.48 1.15e-03 GO:0048468 cell development
1.71 1.19e-03 GO:0051094 positive regulation of developmental process
1.26 1.19e-03 GO:0048518 positive regulation of biological process
1.99 1.27e-03 GO:0003002 regionalization
1.60 1.54e-03 GO:0009887 organ morphogenesis
1.27 1.58e-03 GO:0048522 positive regulation of cellular process
1.55 2.34e-03 GO:0051254 positive regulation of RNA metabolic process
1.65 2.51e-03 GO:0000904 cell morphogenesis involved in differentiation
1.69 2.65e-03 GO:0007268 synaptic transmission
1.40 2.95e-03 GO:0031325 positive regulation of cellular metabolic process
1.65 3.71e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.38 4.93e-03 GO:0009893 positive regulation of metabolic process
2.13 5.33e-03 GO:0009952 anterior/posterior pattern formation
1.66 5.57e-03 GO:0010648 negative regulation of cell communication
1.21 6.07e-03 GO:0007165 signal transduction
1.49 6.56e-03 GO:0007267 cell-cell signaling
1.72 7.99e-03 GO:0048598 embryonic morphogenesis
2.16 9.20e-03 GO:0034330 cell junction organization
1.65 9.51e-03 GO:0023057 negative regulation of signaling
1.65 1.07e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.56 1.09e-02 GO:0048666 neuron development
1.42 1.11e-02 GO:0032879 regulation of localization
1.50 1.56e-02 GO:0009790 embryo development
1.65 1.72e-02 GO:0007409 axonogenesis
1.80 2.03e-02 GO:0061061 muscle structure development
1.72 2.07e-02 GO:0007411 axon guidance
1.62 2.16e-02 GO:0048812 neuron projection morphogenesis
1.46 2.33e-02 GO:0007155 cell adhesion
1.46 2.33e-02 GO:0022610 biological adhesion
1.39 2.37e-02 GO:0007154 cell communication
1.65 2.53e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.26 2.54e-02 GO:0048523 negative regulation of cellular process
1.86 2.62e-02 GO:0048568 embryonic organ development
1.95 3.03e-02 GO:0048732 gland development
1.51 3.04e-02 GO:0032989 cellular component morphogenesis
2.15 3.53e-02 GO:0034329 cell junction assembly
2.15 3.53e-02 GO:0042391 regulation of membrane potential
1.72 3.71e-02 GO:0060284 regulation of cell development
1.51 3.73e-02 GO:0000902 cell morphogenesis
1.19 3.79e-02 GO:0031323 regulation of cellular metabolic process
1.58 3.83e-02 GO:0072358 cardiovascular system development
1.58 3.83e-02 GO:0072359 circulatory system development
1.34 3.88e-02 GO:0051239 regulation of multicellular organismal process
1.62 4.09e-02 GO:0009968 negative regulation of signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 8.00e-09 GO:0044459 plasma membrane part
1.78 2.69e-05 GO:0045202 synapse
1.20 7.08e-05 GO:0005886 plasma membrane
1.20 8.06e-05 GO:0071944 cell periphery
1.71 7.23e-04 GO:0031012 extracellular matrix
1.54 1.41e-03 GO:0030054 cell junction
1.36 1.51e-03 GO:0031226 intrinsic to plasma membrane
1.73 2.40e-03 GO:0005578 proteinaceous extracellular matrix
1.76 2.40e-03 GO:0044456 synapse part
1.35 3.10e-03 GO:0005887 integral to plasma membrane
6.23 6.68e-03 GO:0043256 laminin complex
2.02 2.06e-02 GO:0034703 cation channel complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.74 1.15e-08 GO:0043565 sequence-specific DNA binding
1.55 4.66e-07 GO:0001071 nucleic acid binding transcription factor activity
1.55 4.66e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.48 2.97e-05 GO:0030528 transcription regulator activity
2.09 6.80e-03 GO:0022843 voltage-gated cation channel activity
1.68 1.33e-02 GO:0016563 transcription activator activity
1.73 1.78e-02 GO:0005261 cation channel activity